Article ; Online: Potential impact of the COVID-19 in HIV-infected individuals: a systematic review Impact of the COVID-19 in HIV-Infected Individuals.
Revista da Associacao Medica Brasileira (1992)
2021 Volume 67Suppl 1, Issue Suppl 1, Page(s) 127–156
Abstract: ... HIV infection could be used to prevent COVID-19 infection. ... published after 2019, were describing COVID-19 patients with HIV/AIDS.: Study appraisal: JBI Levels ... not show any relevance directly with the occurrence of COVID-19. Some studies suggest that HIV ...
| Abstract | Background: Although much has been studied about the SARS-Cov-2 virus, its effects, and the effectiveness of possible treatments, little is known about its interaction with other infectious diseases. Objective: The aim is to study its clinical features and morbidity, and mortality outcomes of COVID-19 patients with HIV/AIDS coinfection. Data sources: MEDLINE, Web of Science, Embase, CINAHL, LILACS, Scopus, ClinicalTrials.gov, and Cochrane. Study eligibility criteria: Atudies in any language, published after 2019, were describing COVID-19 patients with HIV/AIDS. Study appraisal: JBI Levels of Evidence, Joanna Briggs Institute. Synthesis methods: As shown in the PRISMA flow diagram, two authors separately screened the search results from the obtained titles and abstracts. Results: Chest CT was observed in patients with pneumonia by SARS-CoV-2 with findings of multiple ground-glass opacities (GGO) in the lungs, there is a need for supplemental oxygenation. One patient developed encephalopathy and complicated tonic-clonic seizures; four patients were transplanted (two, liver; two, kidneys), one patient developed severe SARS-CoV-2 pneumonia and 30 patients died (mortality rate, 11%). Conclusion: HIV did not show any relevance directly with the occurrence of COVID-19. Some studies suggest that HIV-1 infection through induction levels of IFN-I, may to some extent, stop the apparent SARS-CoV-2 infection, thus leading to undetectable RNA. Moreover, some authors suggest retroviral therapy routinely used to control HIV infection could be used to prevent COVID-19 infection. |
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| MeSH term(s) | COVID-19 ; Coinfection ; HIV Infections/complications ; Humans ; SARS-CoV-2 |
| Language | English |
| Publishing date | 2021-07-09 |
| Publishing country | Brazil |
| Document type | Journal Article ; Systematic Review |
| ZDB-ID | 731969-1 |
| ISSN | 1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X |
| ISSN (online) | 1806-9282 |
| ISSN | 0104-4230 ; 0004-5241 ; 0102-843X |
| DOI | 10.1590/1806-9282.67.Suppl1.20200754 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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