Article ; Online: Organizing pneumonia: A late phase complication of COVID-19 responding dramatically to corticosteroids.
2021 Volume 25, Issue 1, Page(s) 101541
Abstract: Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard ... would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered ... therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids ...
| Abstract | Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered. Herein we report a series of three patients, one male and two females, mean age 58.3 years old, admitted for COVID-19 with severe pulmonary disease requiring ventilatory support. The patients underwent chest computed tomography scans due to maintained hypoxemia, which showed a pattern compatible with organizing pneumonia. The patients were treated with a high dose of corticosteroids (prednisone 1 mg/kg PO), showing marked clinical improvement, and decreasing oxygen flow ratio demand. They were discharged after a mean period of 6.3 days of hospitalization. Our report suggests that patients with COVID-19 with organizing pneumonia might benefit from high dose corticosteroids as an adjuvant therapy. |
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| MeSH term(s) | Adrenal Cortex Hormones/adverse effects ; COVID-19 ; Female ; Humans ; Lung ; Male ; Middle Aged ; Pneumonia/drug therapy ; SARS-CoV-2 | |||||
| Chemical Substances | Adrenal Cortex Hormones | |||||
| Language | English | |||||
| Publishing date | 2021-02-06 | |||||
| Publishing country | Brazil | |||||
| Document type | Case Reports | |||||
| ZDB-ID | 2041400-6 | |||||
| ISSN | 1678-4391 ; 1413-8670 | |||||
| ISSN (online) | 1678-4391 | |||||
| ISSN | 1413-8670 | |||||
| DOI | 10.1016/j.bjid.2021.101541 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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