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Article ; Online: Usefulness of positron emission tomography with

Cabrera Villegas, Antonio / Rosel Rioja, Luis Felipe / Ramírez Lasanta, Rafael

2017 Volume 148, Issue 3, Page(s) 140–141

Title translation	Utilidad de la tomografía por emisión de positrones con
Language	Spanish
Publishing date	2017--09
Publishing country	Spain
Document type	Letter
ZDB-ID	411607-0
ISSN	1578-8989 ; 0025-7753
ISSN (online)	1578-8989
ISSN	0025-7753
DOI	10.1016/j.medcli.2016.10.029
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Article: Unusual Uptake of [

Cañete Sánchez, Francisco Manuel / Romero Robles, Leonardo Gabriel / Boulvard Chollet, Xavier Louis / Mangas Losada, María / Garrastachu, Puy / Cabrera Villegas, Antonio / Ramírez Lasanta, Rafael / Delgado Bolton, Roberto

Molecular imaging and radionuclide therapy

2022 Volume 31, Issue 2, Page(s) 145–147

Abstract: A 77-year-old woman with follicular thyroid cancer underwent total thyroidectomy and subsequent Iodine-131 remnant ablation. She had a history of a wide tenosynovial giant cell tumor (TGCT) of the right wrist and hand that had been resected thirteen ... ...

Abstract	A 77-year-old woman with follicular thyroid cancer underwent total thyroidectomy and subsequent Iodine-131 remnant ablation. She had a history of a wide tenosynovial giant cell tumor (TGCT) of the right wrist and hand that had been resected thirteen years ago. Post-therapeutic scintigraphy and single photon emission computed tomography showed mild uptake on the distal right forearm, wrist and hand. Magnetic resonance imaging and posterior histopathology confirmed a relapse of TGCT. No radioiodine adverse effects were reported after a one-year follow-up. As far as we know, this report is the first in the literature to a TGCT visualized on post-therapy radioiodine scan.
Language	English
Publishing date	2022-06-30
Publishing country	Turkey
Document type	Journal Article
ISSN	2146-1414
ISSN	2146-1414
DOI	10.4274/mirt.galenos.2021.40326
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Article ; Online: Impact of COVID-19 on the Health of the General and More Vulnerable Population and Its Determinants: Health Care and Social Survey-ESSOC, Study Protocol.

Sánchez-Cantalejo, Carmen / Rueda, María Del Mar / Saez, Marc / Enrique, Iria / Ferri, Ramón / Fuente, Miguel de La / Villegas, Román / Castro, Luis / Barceló, Maria Antònia / Daponte-Codina, Antonio / Lorusso, Nicola / Cabrera-León, Andrés

International journal of environmental research and public health

2021 Volume 18, Issue 15

Abstract: This manuscript describes the rationale and protocol of a real-world data (RWD) study entitled Health Care and Social Survey (ESSOC, Encuesta Sanitaria y Social). The study's objective is to determine the magnitude, characteristics, and evolution of the ... ...

Abstract	This manuscript describes the rationale and protocol of a real-world data (RWD) study entitled Health Care and Social Survey (ESSOC, Encuesta Sanitaria y Social). The study's objective is to determine the magnitude, characteristics, and evolution of the COVID-19 impact on overall health as well as the socioeconomic, psychosocial, behavioural, occupational, environmental, and clinical determinants of both the general and more vulnerable population. The study integrates observational data collected through a survey using a probabilistic, overlapping panel design, and data from clinical, epidemiological, demographic, and environmental registries. The data will be analysed using advanced statistical, sampling, and machine learning techniques. The study is based on several measurements obtained from three random samples of the Andalusian (Spain) population: general population aged 16 years and over, residents in disadvantaged areas, and people over the age of 55. Given the current characteristics of this pandemic and its future repercussions, this project will generate relevant information on a regular basis, commencing from the beginning of the State of Alarm. It will also establish institutional alliances of great social value, explore and apply powerful and novel methodologies, and produce large, integrated, high-quality and open-access databases. The information described here will be vital for health systems in order to design tailor-made interventions aimed at improving the health care, health, and quality of life of the populations most affected by the COVID-19 pandemic.
MeSH term(s)	COVID-19 ; Delivery of Health Care ; Humans ; Pandemics ; Quality of Life ; SARS-CoV-2 ; Vulnerable Populations
Language	English
Publishing date	2021-07-31
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph18158120
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Article: Commercial and nutraceutical quality of grafted melon cultivated under hydric stress

Villegas Olguín, Marco Antonio / Cabrera De la Fuente, Marcelino / Benavides Mendoza, Adalberto / Juárez Maldonado, Antonio / Sandoval Rangel, Alberto / Fernández Cusimamani, Eloy

Zahradnictví. , v. 47, no. 3

2020

Abstract: Water stress decreases the quality of fruit by generating reactive oxygen species. Grafting is a technique that can improve the efficiency of crop water usage. This work was performed in order to assess the effect of different water stresses on the ... ...

Abstract	Water stress decreases the quality of fruit by generating reactive oxygen species. Grafting is a technique that can improve the efficiency of crop water usage. This work was performed in order to assess the effect of different water stresses on the commercial and nutraceutical quality of a melon fruit. Cantaloupe melon plants, grown under shade houses were grafted onto a creole pumpkin rootstock and grown with different water stresses (20, 30, and 40 kPa). The grafted melon plants under 30-kPa water stress (G30) showed greater fruit firmness and increased catalase activity. The G30 fruits showed an increase in GPX activity of up to 80% over the non-grafted plants. The GSH was higher in fruits subjected to the 40-kPa water tension. The superoxide dismutase showed a 15% greater inhibition in the fruits from the non-grafted plants. At higher water tensions, the DPPH antioxidant activity decreased, while the vitamin C content increased.
Keywords	antioxidant activity ; ascorbic acid ; cantaloupes ; catalase ; dietary supplements ; fruit quality ; fruits ; pumpkins ; reactive oxygen species ; rootstocks ; superoxide dismutase ; water stress ; water utilization
Language	English
Dates of publication	2020-0930
Size	p. 139-149.
Publishing place	Czech Academy of Agricultural Sciences
Document type	Article
ZDB-ID	2054054-1
ISSN	0862-867X
ISSN	0862-867X
DOI	10.17221/139/2019-hortsci
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Pathogen reduction with methylene blue does not have an impact on the clinical effectiveness of COVID-19 convalescent plasma.

Romera Martínez, Irene / Bueno Cabrera, José Luis / Domingo-Morera, José María / López Aguilar, Juan Carlos / Villegas Da Ros, Carolina / García Erce, José Antonio / Sáez Serrano, Isabel / Flores Ballester, Elena / Maglio, Laura Analía / Arbona Castaño, Cristina / Sola Lapeña, Carlos / Guerra Domínguez, Luisa / Berberana Fernández, Margarita / Madrigal Sánchez, María Elena / Rubio Batllés, Martín / Pérez-Olmeda, Mayte / Ramos-Martínez, Antonio / Velasco-Iglesias, Ana / Avendaño-Solá, Cristina /

Duarte, Rafael F

Vox sanguinis

2023 Volume 118, Issue 4, Page(s) 296–300

Abstract: Background and objectives: There is a concern about a possible deleterious effect of pathogen reduction (PR) with methylene blue (MB) on the function of immunoglobulins of COVID-19 convalescent plasma (CCP). We have evaluated whether MB-treated CCP is ... ...

Abstract	Background and objectives: There is a concern about a possible deleterious effect of pathogen reduction (PR) with methylene blue (MB) on the function of immunoglobulins of COVID-19 convalescent plasma (CCP). We have evaluated whether MB-treated CCP is associated with a poorer clinical response compared to other inactivation systems at the ConPlas-19 clinical trial. Materials and methods: This was an ad hoc sub-study of the ConPlas-19 clinical trial comparing the proportion of patients transfused with MB-treated CCP who had a worsening of respiration versus those treated with amotosalen (AM) or riboflavin (RB). Results: One-hundred and seventy-five inpatients with SARS-CoV-2 pneumonia were transfused with a single CCP unit. The inactivation system of the CCP units transfused was MB in 90 patients (51.4%), RB in 60 (34.3%) and AM in 25 (14.3%). Five out of 90 patients (5.6%) transfused with MB-treated CCP had worsening respiration compared to 9 out of 85 patients (10.6%) treated with alternative PR methods (p = 0.220). Of note, MB showed a trend towards a lower rate of respiratory progressions at 28 days (risk ratio, 0.52; 95% confidence interval, 0.18-1.50). Conclusion: Our data suggest that MB-treated CCP does not provide a worse clinical outcome compared to the other PR methods for the treatment of COVID-19.
MeSH term(s)	Humans ; COVID-19/therapy ; COVID-19 Serotherapy ; Immunization, Passive/methods ; Methylene Blue/pharmacology ; Methylene Blue/therapeutic use ; SARS-CoV-2 ; Treatment Outcome
Chemical Substances	Methylene Blue (T42P99266K)
Language	English
Publishing date	2023-02-03
Publishing country	England
Document type	Clinical Trial ; Journal Article
ZDB-ID	80313-3
ISSN	1423-0410 ; 0042-9007
ISSN (online)	1423-0410
ISSN	0042-9007
DOI	10.1111/vox.13406
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Article: Grupo PET de la SEMN: la continuidad del camino.

Cabrera Villegas, Antonio

Revista espanola de medicina nuclear

2006 Volume 25, Issue 3, Page(s) 157–158

Title translation	PET Group of the SEMN (Spanish Society of Nuclear Medicine): continuity of the pathway.
MeSH term(s)	Attitude of Health Personnel ; Diagnostic Equipment/supply & distribution ; Diffusion of Innovation ; Health Services Needs and Demand/statistics & numerical data ; Interdisciplinary Communication ; Medical Oncology ; Nuclear Medicine/organization & administration ; Nuclear Medicine/trends ; Positron-Emission Tomography/instrumentation ; Radiology ; Societies, Medical/organization & administration ; Societies, Medical/trends ; Spain ; Technology, High-Cost ; Tomography, X-Ray Computed/instrumentation
Language	Spanish
Publishing date	2006-05-25
Publishing country	Spain
Document type	Editorial
ZDB-ID	639249-0
ISSN	1578-200X ; 0212-6982
ISSN (online)	1578-200X
ISSN	0212-6982
DOI	10.1157/13088409
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Article ; Online: Factors related to the development of high antibody titres against SARS-CoV-2 in convalescent plasma donors from the ConPlas-19 trial.

Romera Martínez, Irene / Avendaño-Solá, Cristina / Villegas Da Ros, Carolina / Bosch Llobet, Alba / García Erce, José Antonio / González Fraile, María Isabel / Guerra Domínguez, Luisa / Vicuña Andrés, Isabel / Anguita Velasco, Javier / González Rodríguez, Victoria Paz / Contreras, Enric / Urcelay Uranga, Sabin / Pajares Herraiz, Ángel Luis / Jimenez-Marco, Teresa / Ojea Pérez, Ana María / Arroyo Rodríguez, José Luis / Pérez-Olmeda, Mayte / Ramos-Martínez, Antonio / Velasco-Iglesias, Ana /

Bueno Cabrera, José Luis / Duarte, Rafael F

Vox sanguinis

2023 Volume 119, Issue 1, Page(s) 27–33

Abstract: Background and objectives: The efficacy of COVID-19 convalescent plasma (CP) associates with high titres of antibodies. ConPlas-19 clinical trial showed that CP reduces the risk of progression to severe COVID-19 at 28 days. Here, we aim to study ConPlas- ...

Abstract	Background and objectives: The efficacy of COVID-19 convalescent plasma (CP) associates with high titres of antibodies. ConPlas-19 clinical trial showed that CP reduces the risk of progression to severe COVID-19 at 28 days. Here, we aim to study ConPlas-19 donors and characteristics that associate with high anti-SARS-CoV-2 antibody levels. Materials and methods: Four-hundred donors were enrolled in ConPlas-19. The presence and titres of anti-SARS-CoV-2 antibodies were evaluated by EUROIMMUN anti-SARS-CoV-2 S1 IgG ELISA. Results: A majority of 80.3% of ConPlas-19 donor candidates had positive EUROIMMUN test results (ratio ≥1.1), and of these, 51.4% had high antibody titres (ratio ≥3.5). Antibody levels decline over time, but nevertheless, out of 37 donors tested for an intended second CP donation, over 90% were still EUROIMMUN positive, and nearly 75% of those with high titres maintained high titres in the second sample. Donors with a greater probability of developing high titres of anti-SARS-CoV-2 antibodies include those older than 40 years of age (RR 2.06; 95% CI 1.24-3.42), with more than 7 days of COVID-19 symptoms (RR 1.89; 95% CI 1.05-3.43) and collected within 4 months from infection (RR 2.61; 95% CI 1.16-5.90). Male donors had a trend towards higher titres compared with women (RR 1.67; 95% CI 0.91-3.06). Conclusion: SARS-CoV-2 CP candidate donors' age, duration of COVID-19 symptoms and time from infection to donation associate with the collection of CP with high antibody levels. Beyond COVID-19, these data are relevant to inform decisions to optimize the CP donor selection process in potential future outbreaks.
MeSH term(s)	Female ; Humans ; Male ; Antibodies, Neutralizing ; Antibodies, Viral ; Blood Donors ; COVID-19/therapy ; COVID-19 Serotherapy ; Immunization, Passive/methods ; Immunoglobulin G ; SARS-CoV-2 ; Clinical Trials as Topic
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral ; Immunoglobulin G
Language	English
Publishing date	2023-11-20
Publishing country	England
Document type	Journal Article
ZDB-ID	80313-3
ISSN	1423-0410 ; 0042-9007
ISSN (online)	1423-0410
ISSN	0042-9007
DOI	10.1111/vox.13561
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Article ; Online: [

Cabrera Villegas, Antonio / Romero Robles, Leonardo G / Boulvard Chollet, Xavier L E / Albornoz Almada, M Clara / Mangas Losada, María / Garrastachu, Puy / Cañete Sánchez, Francisco M / Ramírez Lasanta, Rafael / Delgado Bolton, Roberto C

European journal of nuclear medicine and molecular imaging

2020 Volume 48, Issue 3, Page(s) 786–793

Abstract: Purpose: Spain has been one of the most affected countries by the COVID-19 pandemic, being among the countries with worse numbers, including the death rate. However, most patients are asymptomatic, although they are very contagious. The objective of ... ...

Abstract	Purpose: Spain has been one of the most affected countries by the COVID-19 pandemic, being among the countries with worse numbers, including the death rate. However, most patients are asymptomatic, although they are very contagious. The objective of this study was to investigate the incidence in oncological patients infected with SARS-CoV-2 that are asymptomatic for COVID-19 and at home and that undergo PET/CT for oncologic indications, nonrelated to COVID-19, finding in the PET/CT lung alterations that are suggestive of SARS-CoV-2 infection. Methods: During the period of maximum incidence of the global pandemic in one of the most affected regions of Spain, there were 145 patients that met inclusion and exclusion criteria and were included in the study. Imaging findings previously described such as ground-glass opacities with low [ Results: Suspicious lung imaging findings were present in 7 of 145 patients (4.8%). Five of these 7 patients were confirmed as presenting SARS-CoV-2 infection, this is, COVID-19. In the remaining two, it was not possible to confirm the presence of COVID-19 with RT-PCR, although in one of them, PET/CT allowed an early diagnosis of a lung infection related to a bacterial pneumonic infection that was promptly and adequately treated with antibiotics. Conclusion: These results confirm that the prevalence of SARS-CoV-2 infection is higher than suspected and that there are asymptomatic patients that are attending imaging departments to be explored for their baseline oncologic processes. In these patients, PET/CT allows an early diagnosis of COVID-19.
MeSH term(s)	Asymptomatic Infections ; COVID-19 ; Female ; Fluorodeoxyglucose F18/administration & dosage ; Humans ; Male ; Neoplasms/diagnostic imaging ; Neoplasms/epidemiology ; Pandemics ; Positron Emission Tomography Computed Tomography/methods ; SARS-CoV-2 ; Spain/epidemiology
Chemical Substances	Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Keywords	covid19
Language	English
Publishing date	2020-09-16
Publishing country	Germany
Document type	Journal Article
ZDB-ID	8236-3
ISSN	1619-7089 ; 0340-6997 ; 1619-7070
ISSN (online)	1619-7089
ISSN	0340-6997 ; 1619-7070
DOI	10.1007/s00259-020-04979-5
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Article ; Online: 18F-FDG PET/CT in Hodgkin Lymphoma With Unsuspected COVID-19.

Boulvard Chollet, Xavier L E / Romero Robles, Leonardo G / Garrastachu, Puy / Cabrera Villegas, Antonio / Albornoz Almada, M Clara / Colletti, Patrick M / Rubello, Domenico / Ramírez Lasanta, Rafael / Delgado Bolton, Roberto C

Clinical nuclear medicine

2020 Volume 45, Issue 8, Page(s) 652–653

Abstract: We present an asymptomatic 70-year-old man referred for an F-FDG PET/CT for initial staging of a Hodgkin lymphoma. F-FDG PET/CT showed bilateral cervical lymphadenopathy (stage II). Incidentally, the CT demonstrated bilateral ground-glass opacities with ... ...

Abstract	We present an asymptomatic 70-year-old man referred for an F-FDG PET/CT for initial staging of a Hodgkin lymphoma. F-FDG PET/CT showed bilateral cervical lymphadenopathy (stage II). Incidentally, the CT demonstrated bilateral ground-glass opacities with low-grade F-FDG activity. CT findings were suspicious for COVID-19 pneumonitis. The COVID-19 reverse transcriptase polymerase chain reaction (RT-PCR) examination result was negative. Given the high clinical suspicion for COVID-19, the patient was isolated and repeat RT-PCR was positive at 72 hours. RT-PCR may be falsely negative in early COVID-19 disease, even with positive CT findings.
MeSH term(s)	Aged ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/diagnostic imaging ; Fluorodeoxyglucose F18 ; Hodgkin Disease/complications ; Humans ; Male ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnostic imaging ; Positron Emission Tomography Computed Tomography ; SARS-CoV-2
Chemical Substances	Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Keywords	covid19
Language	English
Publishing date	2020-06-09
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	197628-x
ISSN	1536-0229 ; 0363-9762
ISSN (online)	1536-0229
ISSN	0363-9762
DOI	10.1097/RLU.0000000000003143
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Article ; Online: 18F-FDG PET/CT in Hodgkin Lymphoma With Unsuspected COVID-19

Boulvard Chollet, Xavier L.E. / Romero Robles, Leonardo G. / Garrastachu, Puy / Cabrera Villegas, Antonio / Albornoz Almada, M. Clara / Colletti, Patrick M. / Rubello, Domenico / Ramírez Lasanta, Rafael / Delgado Bolton, Roberto C.

Clinical Nuclear Medicine

2020 Volume 45, Issue 8, Page(s) 652–653

Keywords	Radiology Nuclear Medicine and imaging ; General Medicine ; covid19
Language	English
Publisher	Ovid Technologies (Wolters Kluwer Health)
Publishing country	us
Document type	Article ; Online
ZDB-ID	197628-x
ISSN	1536-0229 ; 0363-9762
ISSN (online)	1536-0229
ISSN	0363-9762
DOI	10.1097/rlu.0000000000003143
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