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  1. Article ; Online: A K

    Wang, Qiyue / Li, Fangyuan / Liang, Zeyu / Liao, Hongwei / Zhang, Bo / Lin, Peihua / Liu, Xun / Hu, Shen / Lee, Jiyoung / Ling, Daishun

    National science review

    2022  Volume 9, Issue 7, Page(s) nwac080

    Abstract: ... we demonstrate a potassium ion (K ...

    Abstract Although molecular imaging probes have the potential to non-invasively diagnose a tumor, imaging probes that can detect a tumor and simultaneously identify tumor malignancy remain elusive. Here, we demonstrate a potassium ion (K
    Language English
    Publishing date 2022-04-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 2745465-4
    ISSN 2053-714X ; 2053-714X
    ISSN (online) 2053-714X
    ISSN 2053-714X
    DOI 10.1093/nsr/nwac080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Differential contribution of THIK-1 K

    Rifat, Ali / Ossola, Bernardino / Bürli, Roland W / Dawson, Lee A / Brice, Nicola L / Rowland, Anna / Lizio, Marina / Xu, Xiao / Page, Keith / Fidzinski, Pawel / Onken, Julia / Holtkamp, Martin / Heppner, Frank L / Geiger, Jörg R P / Madry, Christian

    Journal of neuroinflammation

    2024  Volume 21, Issue 1, Page(s) 58

    Abstract: ... inflammasome and subsequent release of IL-1β. Extracellular ATP is a strong activator of NLRP3 by inducing K ...

    Abstract Neuroinflammation is highly influenced by microglia, particularly through activation of the NLRP3 inflammasome and subsequent release of IL-1β. Extracellular ATP is a strong activator of NLRP3 by inducing K
    MeSH term(s) Humans ; Microglia/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Neuroinflammatory Diseases ; Ion Channels/metabolism ; Adenosine Triphosphate/pharmacology ; Adenosine Triphosphate/metabolism ; Receptors, Purinergic P2X7/metabolism
    Chemical Substances NLR Family, Pyrin Domain-Containing 3 Protein ; Ion Channels ; Adenosine Triphosphate (8L70Q75FXE) ; Receptors, Purinergic P2X7
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2156455-3
    ISSN 1742-2094 ; 1742-2094
    ISSN (online) 1742-2094
    ISSN 1742-2094
    DOI 10.1186/s12974-024-03042-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: k

    MacDonald, Madolyn L / Polson, Shawn W / Lee, Kelvin H

    mSphere

    2021  Volume 6, Issue 2

    Abstract: Adventitious agent detection during the production of vaccines and biotechnology-based medicines is of critical importance to ensure the final product is free from any possible viral contamination. Increasing the speed and accuracy of viral detection is ... ...

    Abstract Adventitious agent detection during the production of vaccines and biotechnology-based medicines is of critical importance to ensure the final product is free from any possible viral contamination. Increasing the speed and accuracy of viral detection is beneficial as a means to accelerate development timelines and to ensure patient safety. Here, several rapid viral metagenomics approaches were tested on simulated next-generation sequencing (NGS) data sets and existing data sets from virus spike-in studies done in CHO-K1 and HeLa cell lines. It was observed that these rapid methods had comparable sensitivity to full-read alignment methods used for NGS viral detection for these data sets, but their specificity could be improved. A method that first filters host reads using KrakenUniq and then selects the virus classification tool based on the number of remaining reads is suggested as the preferred approach among those tested to detect nonlatent and nonendogenous viruses. Such an approach shows reasonable sensitivity and specificity for the data sets examined and requires less time and memory as full-read alignment methods.
    MeSH term(s) Cell Line ; Computational Biology/methods ; DNA, Viral/genetics ; Drug Contamination/prevention & control ; HeLa Cells ; High-Throughput Nucleotide Sequencing/methods ; Humans ; Metagenomics/methods ; RNA, Viral/genetics ; Vaccines/standards ; Viruses/genetics ; Viruses/isolation & purification
    Chemical Substances DNA, Viral ; RNA, Viral ; Vaccines
    Language English
    Publishing date 2021-04-21
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/mSphere.01336-20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Comparison of (K

    Fisher, John G / Sim, Su-Hyeon / Ðoàn, Trung Thành / Uwiragiye, Eugenie / Mok, Jungwi / Lee, Junseong

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 10

    Abstract: K ...

    Abstract (K
    Language English
    Publishing date 2023-05-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16103638
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  5. Article ; Online: Transformation of K

    Lee, Hyungseok / Yoo, Byeongjun / Kim, Dawoon / Cha, Joonil / Kang, Yeo Kyung / Cho, Sung-Pyo / Hyeon, Taeghwan / Kim, Myung-Gil / Kanatzidis, Mercouri G / Chung, In

    Journal of the American Chemical Society

    2023  Volume 145, Issue 29, Page(s) 15951–15962

    Abstract: ... by hard-soft acid-base (HSAB) chemistry. We show that the three-dimensional framework K ...

    Abstract The ability to manipulate crystal structures using kinetic control is of broad interest because it enables the design of materials with structures, compositions, and morphologies that may otherwise be unattainable. Herein, we report the low-temperature structural transformation of bulk inorganic crystals driven by hard-soft acid-base (HSAB) chemistry. We show that the three-dimensional framework K
    Language English
    Publishing date 2023-07-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c03925
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
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  6. Article ; Online: Repurposing the K

    Lee, Ruth D / Chen, Yi-Je / Nguyen, Hai M / Singh, Latika / Dietrich, Connor J / Pyles, Benjamin R / Cui, Yanjun / Weinstein, Jonathan R / Wulff, Heike

    Translational stroke research

    2023  

    Abstract: Senicapoc, a small molecule inhibitor of the calcium-activated potassium channel KCa3.1, was safe and well-tolerated in clinical trials for sickle cell anemia. We previously reported proof-of-concept data suggesting that both pharmacological inhibition ... ...

    Abstract Senicapoc, a small molecule inhibitor of the calcium-activated potassium channel KCa3.1, was safe and well-tolerated in clinical trials for sickle cell anemia. We previously reported proof-of-concept data suggesting that both pharmacological inhibition and genetic deletion of KCa3.1 reduces infarction and improves neurologic recovery in rodents by attenuating neuroinflammation. Here we evaluated the potential of repurposing senicapoc for ischemic stroke. In cultured microglia, senicapoc inhibited KCa3.1 currents with an IC
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2541897-X
    ISSN 1868-601X ; 1868-4483
    ISSN (online) 1868-601X
    ISSN 1868-4483
    DOI 10.1007/s12975-023-01152-6
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  7. Article ; Online: K

    Lee, Chongmin / Kim, Sun Kyung / Chang, Hankwon / Jang, Hee Dong

    Nano-micro letters

    2019  Volume 12, Issue 1, Page(s) 10

    Abstract: ... as efficient electrode materials for supercapacitors. Potassium hexa-titanate (K ...

    Abstract One-dimensional alkali metal titanates containing potassium, sodium, and lithium are of great concern owing to their high ion mobility and high specific surface area. When those titanates are combined with conductive materials such as graphene, carbon nanotube, and carbon nanofiber, they are able to be employed as efficient electrode materials for supercapacitors. Potassium hexa-titanate (K
    Language English
    Publishing date 2019-12-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2642093-4
    ISSN 2150-5551 ; 2311-6706
    ISSN (online) 2150-5551
    ISSN 2311-6706
    DOI 10.1007/s40820-019-0344-3
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  8. Book ; Online: K-Hairstyle

    Kim, Taewoo / Chung, Chaeyeon / Park, Sunghyun / Gu, Gyojung / Nam, Keonmin / Choe, Wonzo / Lee, Jaesung / Choo, Jaegul

    A Large-scale Korean Hairstyle Dataset for Virtual Hair Editing and Hairstyle Classification

    2021  

    Abstract: ... we introduce a novel large-scale Korean hairstyle dataset, K-hairstyle, containing 500,000 high-resolution ... images. In addition, K-hairstyle includes various hair attributes annotated by Korean expert hairstylists ... such as hair dyeing, hairstyle transfer, and hairstyle classification. K-hairstyle is publicly available ...

    Abstract The hair and beauty industry is a fast-growing industry. This led to the development of various applications, such as virtual hair dyeing or hairstyle transfer, to satisfy the customer's needs. Although several hairstyle datasets are available for these applications, they often consist of a relatively small number of images with low resolution, thus limiting their performance on high-quality hair editing. In response, we introduce a novel large-scale Korean hairstyle dataset, K-hairstyle, containing 500,000 high-resolution images. In addition, K-hairstyle includes various hair attributes annotated by Korean expert hairstylists as well as hair segmentation masks. We validate the effectiveness of our dataset via several applications, such as hair dyeing, hairstyle transfer, and hairstyle classification. K-hairstyle is publicly available at https://psh01087.github.io/K-Hairstyle/.

    Comment: ICIP 2021 final version
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Publishing date 2021-02-11
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Recent Developments in (K, Na)NbO

    Lee, Geun-Soo / Kim, Jung-Soo / Kim, Seung-Hyun / Kwak, San / Kim, Bumjoo / Kim, In-Su / Nahm, Sahn

    Micromachines

    2024  Volume 15, Issue 3

    Abstract: K ...

    Abstract (K
    Language English
    Publishing date 2024-02-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi15030325
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  10. Article ; Online: Role of K

    Lee, Ken / Isogai, Ayu / Antoh, Minori / Kajioka, Shunichi / Eto, Masatoshi / Hashitani, Hikaru

    European journal of pharmacology

    2018  Volume 818, Page(s) 30–37

    Abstract: To explore the roles of various K ...

    Abstract To explore the roles of various K
    MeSH term(s) Action Potentials/drug effects ; Animals ; Guinea Pigs ; Indoles/pharmacology ; Muscle Contraction/drug effects ; Muscle, Smooth/drug effects ; Muscle, Smooth/metabolism ; Muscle, Smooth/physiology ; Nifedipine/pharmacology ; Oximes/pharmacology ; Potassium Channels/metabolism ; Urinary Bladder/drug effects ; Urinary Bladder/metabolism ; Urinary Bladder/physiology
    Chemical Substances 6,7-dichloro-1H-indole-2,3-dione 3-oxime ; Indoles ; Oximes ; Potassium Channels ; Nifedipine (I9ZF7L6G2L)
    Language English
    Publishing date 2018-01-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 80121-5
    ISSN 1879-0712 ; 0014-2999
    ISSN (online) 1879-0712
    ISSN 0014-2999
    DOI 10.1016/j.ejphar.2017.10.024
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 522: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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