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Article ; Online: A Case of Coil Embolization with Crossing Y-Configuration Stenting for a Recurrent IC-PC Aneurysm after Clipping.

Sato, Shinji / Kokubo, Yasuaki / Kawanami, Kanako / Itagaki, Hiroshi / Matsumoto, Yasushi / Sonoda, Yukihiko

Journal of neuroendovascular therapy

2021 Volume 16, Issue 5, Page(s) 250–256

Abstract: Objective: We report a case in which coil embolization using crossing Y-configuration stenting was ... residual neck was required. Therefore, crossing Y-configuration stenting was deployed ... year later.: Conclusion: Coil embolization by crossing Y-configuration stenting is a viable ...

Abstract	Objective: We report a case in which coil embolization using crossing Y-configuration stenting was effective for an internal carotid-posterior communicating artery (IC-PC) aneurysm with repeated recurrence after clipping. Case presentation: The patient was a 57-year-old woman. Nine months after undergoing clipping for a ruptured right IC-PC aneurysm at 55 years of age, she developed a second subarachnoid hemorrhage (SAH) due to recurrence of the aneurysm and underwent clipping at the same site. A third SAH due to rupture of the left IC-PC aneurysm developed 1.5 years after the second clipping. Simultaneously, recurrence of a right IC-PC aneurysm was noted and she was referred to our department. The recurrent right IC-PC aneurysm was considered to have originated from the distal to the initial neck. It was 7 mm in size and had an irregularly shaped wide neck. As it was assumed that there would be marked adhesion due to repeated surgery, we decided to treat the aneurysm by coil embolization instead of direct surgery. Although the aneurysm neck partially involved the posterior communicating artery (Pcom), tight packing with a minimal residual neck was required. Therefore, crossing Y-configuration stenting was deployed on the internal carotid artery and Pcom using two Neuroform Atlas stents, and coil embolization was performed by the jail technique. The recurrent aneurysm was obliterated. There were no deficits or thrombotic complications after surgery. On DSA follow-up, no compaction or recurrence was observed, and the Pcom was well visualized one year later. Conclusion: Coil embolization by crossing Y-configuration stenting is a viable treatment option for a recurrent IC-PC wide neck aneurysm.
Language	English
Publishing date	2021-09-11
Publishing country	Japan
Document type	Case Reports
ISSN	2186-2494
ISSN (online)	2186-2494
DOI	10.5797/jnet.cr.2021-0065
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Article: Rapid Progression of Aortitis Caused by Methicillin-Sensitive Staphylococcus Aureus in a Patient With Pneumonia: A Case Report.

Itagaki, Hideya / Ooizumi, Tomoya / Sanada, Chiho / Abe, Yoshinobu / Endo, Tomoyuki

Cureus

2024 Volume 16, Issue 2, Page(s) e54674

Abstract: Infected aortic aneurysm is a rare but fatal disease that occurs through various mechanisms. In this report, we describe the case of a patient who was hospitalized for acute pneumonia and developed an infected aortic aneurysm in the descending aorta ... ...

Abstract	Infected aortic aneurysm is a rare but fatal disease that occurs through various mechanisms. In this report, we describe the case of a patient who was hospitalized for acute pneumonia and developed an infected aortic aneurysm in the descending aorta during the hospitalization. A 73-year-old Japanese man presented to the emergency department with a chief complaint of fever. He had a history of chronic renal failure due to nephrosclerosis and was on regular hemodialysis three times a week. The patient presented with an elevated inflammatory response, anemia, and low platelet counts after various tests. Computed tomography (CT) showed ground-glass opacity in the left lung with a small amount of pleural effusion, leading to a diagnosis of pneumonia. The patient was admitted to the hospital on the same day, and a course of antibiotics (ceftriaxone [CTRX]) was started. On the fourth day of hospitalization,
Language	English
Publishing date	2024-02-22
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.54674
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Article: Sexing of porcine embryo by in situ hybridization using chromosome Y- and 1-specific DNA probes.

Kawarasaki, T / Matsumoto, K / Chikyu, M / Itagaki, Y / Horiuchi, A

Theriogenology

2000 Volume 53, Issue 7, Page(s) 1501–1509

Abstract: ... Y- and 1-bearing boar spermatozoa was applicable for sexing embryos. Porcine embryos were recovered ... of Y-bearing spermatozoa. Hybridization was performed using digoxigenin (dig)-labeled chromosome Y ...

Abstract	This study was carried out to determine if a rapid, simultaneous detection system using chromosome Y- and 1-bearing boar spermatozoa was applicable for sexing embryos. Porcine embryos were recovered from gilts and sows 4 to 6 d after mating, and whole embryos or biopsy cells were mounted on a glass slide with a small amount of fixative (methanol: acetic acid: distilled water = 9:1:4). The samples were then stained by means of a fluorescence in situ hybridization (FISH) procedure developed specifically for the detection of Y-bearing spermatozoa. Hybridization was performed using digoxigenin (dig)-labeled chromosome Y- specific DNA, and biotin-labeled chromosome 1-specific DNA sequences were detected as a signal of FITC and Texas Red on nucleus visualized DAPI-stain. Proportions of whole embryos labeled with chromosome 1-probe were 17 and 97% at the 3 to 16 and > or = 32 cell stage, respectively. Of the 93 biopsied embryos analyzed by FISH, 85 embryos (91%) could be accurately classified as male or female. Of the 65 biopsied embryos, 60 embryos (92%) had a clear blastocoele and a inner cell mass after 48 h of culture in vitro, and these embryos were evaluated as available embryos. One out of 4 recipient gilts which received sexed embryos at transfer farrowed 12 piglets of the expected sex. The results of this study demonstrated that porcine embryos at the > or = 32 cell stage can be sexed within 2 h using the FISH method. Moreover further development of the FISH technique could make it an effective tool for the study of early porcine embryos and for the control of porcine sex.
MeSH term(s)	Animals ; Culture Techniques ; DNA Probes ; Embryo Transfer/veterinary ; Female ; In Situ Hybridization, Fluorescence/veterinary ; Male ; Sequence Analysis, DNA ; Sex Determination Analysis/methods ; Sex Determination Analysis/veterinary ; Swine/embryology ; Y Chromosome
Chemical Substances	DNA Probes
Language	English
Publishing date	2000-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	189232-0
ISSN	1879-3231 ; 0093-691X
ISSN (online)	1879-3231
ISSN	0093-691X
DOI	10.1016/s0093-691x(00)00292-2
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Zs.A 3929: Show issues

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Article: Overwhelming Post-splenectomy Infection Caused by Escherichia coli 20 Years After Splenectomy: A Case Report.

Abe, Yoshinobu / Itagaki, Hideya / Endo, Tomoyuki

Cureus

2023 Volume 15, Issue 7, Page(s) e42184

Abstract: Post-splenectomy patients are at increased risk of infection. This complication is called overwhelming post-splenectomy infection (OPSI), which is uncommon but has high mortality. We describe a case of a man in his 80s who presented with septic shock ... ...

Abstract	Post-splenectomy patients are at increased risk of infection. This complication is called overwhelming post-splenectomy infection (OPSI), which is uncommon but has high mortality. We describe a case of a man in his 80s who presented with septic shock with purpura fulminans caused by pyelonephritis. He had undergone a splenectomy in his 50s and had been taking prednisolone for the past six months for suspected immunoglobulin G4 (IgG4)-related disease. He was admitted to the intensive care unit but died the day after admission. OPSI is generally caused by encapsulated bacteria. However, in the present case, the causative agent was
Language	English
Publishing date	2023-07-20
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.42184
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Article ; Online: Coexistence of thought types as an attentional state during a sustained attention task.

Shinagawa, Kazushi / Itagaki, Yu / Umeda, Satoshi

Scientific reports

2023 Volume 13, Issue 1, Page(s) 1581

Abstract: Some studies have asked participants about attentional state on a scale from on-task to off-task, which set the middle option as attention focused on both, including the possibility of the coexistence of thoughts. In addition, studies using ... ...

Abstract	Some studies have asked participants about attentional state on a scale from on-task to off-task, which set the middle option as attention focused on both, including the possibility of the coexistence of thoughts. In addition, studies using multidimensional probes explicitly assumed coexistence within spontaneous thoughts and task-focus dimensions. Although several studies have assumed the coexistence of some thought dimensions, none has explored whether these are different types of thoughts (task-focus, mind-wandering, task-related, external stimuli-related). To examine whether this coexistence of thought types occurred, we used thought probes to determine the degree of immersion in each. The participants responded to probes presented at random during a sustained attention task. The results revealed a mixture of thought types in many self-reports. In addition, the state of attentional allocation behind self-reports was estimated using the hidden Markov model. We observed the following attentional states: task-focused, task-unrelated, task-related, external stimuli-focused, and task-focused-but also focused on other thoughts. These results suggest that individuals can simultaneously allocate attention to thought types and discriminate between reporting. In some cases, probe options should also be considered for this coexistence. We also examined the relationship between self-reports and behavioral indexes, and discussed the necessity of separately measuring the degree of immersion for each thought type.
MeSH term(s)	Humans ; Self Report ; Attention ; Thinking
Language	English
Publishing date	2023-01-28
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-28690-1
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Article ; Online: Persistent weekly paclitaxel-induced peripheral neuropathy in early breast cancer patients enrolled in a randomized trial of cryotherapy.

Shigematsu, Hideo / Kimura, Yuri / Itagaki, Tomoko / Yasui, Daisuke

Medicine

2023 Volume 102, Issue 16, Page(s) e33580

Abstract: Chemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect of weekly paclitaxel-based chemotherapy for breast cancer, that can persist for years. Cryotherapy therapy is effective for preventing early CIPN, but its protective effect on ... ...

Abstract	Chemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect of weekly paclitaxel-based chemotherapy for breast cancer, that can persist for years. Cryotherapy therapy is effective for preventing early CIPN, but its protective effect on persistent CIPN is uncertain. This is a cross-sectional study conducted as an ancillary analysis of a randomized trial investigating the preventive effect of cryotherapy on CIPN in breast cancer patients receiving weekly paclitaxel-based chemotherapy (UMIN000034966). Eligible patients were evaluated for CIPN at more than a year after completion of the chemotherapy (persistent CIPN). CIPN was defined as a 6 or more points reduction from baseline in the Functional Assessment of Cancer Therapy-Neurotoxicity (FACT-NTX) score. The incidence of early and persistent CIPN was compared between cryotherapy and control groups. Thirty-eight patients were examined for both early and persistent CIPN. The median time from completion of the weekly paclitaxel-based chemotherapy to the questionnaire for persistent CIPN was 2.3 (1.3-3.1) years. In all 38 patients, persistent CIPN was demonstrated in 10 (26.3%), respectively. There was a numerical, however not significant, reduction in the incidence of persistent CIPN (15.8% vs 36.8%, P = .1) in the cryotherapy group compared with the control group, respectively. In multivariate logistic regression analysis, age ≥ 65 was a substantial risk factor for persistent CIPN (HR: 14.7, 95%CI: 1.7-130.7, P = .01). In breast cancer patients receiving adjuvant weekly paclitaxel-based chemotherapy, cryotherapy resulted in a numerical, however not significant, reduction in the incidence of persistent CIPN and age>=65 was a risk factor for persistent CIPN.
MeSH term(s)	Humans ; Aged ; Female ; Paclitaxel/adverse effects ; Breast Neoplasms/therapy ; Cross-Sectional Studies ; Peripheral Nervous System Diseases/chemically induced ; Peripheral Nervous System Diseases/epidemiology ; Peripheral Nervous System Diseases/therapy ; Cryotherapy/methods ; Antineoplastic Agents/therapeutic use
Chemical Substances	Paclitaxel (P88XT4IS4D) ; Antineoplastic Agents
Language	English
Publishing date	2023-04-21
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000033580
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Ua VI Zs.171: Show issues

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Article ; Online: Spontaneous Improvement of Aortitis Associated with Severe COVID-19 Infection-A Case Report.

Shimada, Takashi / Itagaki, Hideya / Shirota, Yuko / Endo, Tomoyuki

Medicina (Kaunas, Lithuania)

2023 Volume 59, Issue 5

Abstract: Aortitis is a rare complication of the coronavirus disease 2019 (COVID-19) and is often treated empirically with steroids. We present a case of spontaneous resolution of aortitis without treatment. A 65-year-old man was admitted to our intensive care ... ...

Abstract	Aortitis is a rare complication of the coronavirus disease 2019 (COVID-19) and is often treated empirically with steroids. We present a case of spontaneous resolution of aortitis without treatment. A 65-year-old man was admitted to our intensive care unit for severe COVID-19 pneumonia and underwent rehabilitation in the general ward. On day 12, he developed fever, and on day 13, he developed right cervical pain and increased inflammatory markers. On day 16, a cervical echocardiogram showed vasculitis in the right common carotid artery, and on day 17, computed tomography (CT) of the neck showed thickening of the arterial wall of the right common to the internal carotid arteries. A retrospective assessment of the CT scan on day 12 showed wall thickening from the thoracic aorta to the abdominal aorta, and a diagnosis of aortitis was made. Autoantibody analysis, culture, and magnetic resonance imaging (MRI) of the head and neck showed no abnormalities. During the investigation of the cause of aortitis, the fever and inflammatory reaction spontaneously resolved and the right cervical pain gradually improved. Therefore, the patient was diagnosed with transient COVID-19-related aortitis. To our knowledge, this is the first report describing the spontaneous resolution of COVID-19-related aortitis.
MeSH term(s)	Male ; Humans ; Aged ; Aortitis/complications ; Aortitis/diagnostic imaging ; Retrospective Studies ; Neck Pain/complications ; COVID-19/complications ; Aorta, Thoracic ; Fever/complications
Language	English
Publishing date	2023-04-22
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina59050816
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Article ; Online: Do aspermic (parthenogenetic)

Ohari, Y / Hayashi, K / Takashima, Y / Itagaki, T

Journal of helminthology

2021 Volume 95, Page(s) e36

Abstract: Across Far East Asia, aspermic Fasciola forms are found endemically. They have abnormal spermatogenesis and oogenesis, and it is presumed that their progeny are produced parthenogenetically and clonally. Because of this, they are also termed ... ...

Abstract	Across Far East Asia, aspermic Fasciola forms are found endemically. They have abnormal spermatogenesis and oogenesis, and it is presumed that their progeny are produced parthenogenetically and clonally. Because of this, they are also termed parthenogenic Fasciola forms. Currently, there is no evidence that they do indeed reproduce parthenogenetically and clonally. In this study, the multilocus genetic type (MLG) in 12 microsatellite markers of adult flukes and their subsequent progeny larvae were analysed using two laboratory aspermic Fasciola triploid strains. The MLGs of adults and their larvae were identical for all markers evaluated, suggesting that these strains reproduce their progeny clonally. The deviation between theoretical and actual frequency within the larvae genotype of the Fh_6 locus resulted in the inability for self-fertilization within individual adult flukes. These findings strongly suggested that aspermic Fasciola forms reproduce their progeny by means of parthenogenesis, possibly gynogenesis.
MeSH term(s)	Animals ; Asia ; Far East ; Fasciola ; Haplotypes ; Male ; NADH Dehydrogenase/genetics ; Parthenogenesis
Chemical Substances	NADH Dehydrogenase (EC 1.6.99.3)
Language	English
Publishing date	2021-07-21
Publishing country	England
Document type	Journal Article
ZDB-ID	390188-9
ISSN	1475-2697 ; 0022-149X
ISSN (online)	1475-2697
ISSN	0022-149X
DOI	10.1017/S0022149X21000328
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Article ; Online: Emergency administration of fibrinogen concentrate for haemorrhage: systematic review and meta-analysis.

Itagaki, Yuki / Hayakawa, Mineji / Takahashi, Yuki / Hirano, Satoshi / Yamakawa, Kazuma

World journal of emergency surgery : WJES

2023 Volume 18, Issue 1, Page(s) 27

Abstract: Introduction: The occurrence of massive haemorrhages in various emergency situations increases the need for blood transfusions and increases the risk of mortality. Fibrinogen concentrate (FC) use may increase plasma fibrinogen levels more rapidly than ... ...

Abstract	Introduction: The occurrence of massive haemorrhages in various emergency situations increases the need for blood transfusions and increases the risk of mortality. Fibrinogen concentrate (FC) use may increase plasma fibrinogen levels more rapidly than fresh-frozen product or cryoprecipitate use. Previous several systematic reviews and meta-analyses have not effectively demonstrated FC efficacy in significantly improving the risk of mortality and reducing transfusion requirements. In this study, we investigated the use of FC for haemorrhages in emergency situations. Methods and analysis: In this systematic review and meta-analysis, we included controlled trials, but excluded randomized controlled trials (RCTs) in elective surgeries. The study population consisted of patients with haemorrhages in emergency situations, and the intervention was emergency supplementation of FC. The control group was administered with ordinal transfusion or placebo. The primary and secondary outcomes were in-hospital mortality and the amount of transfusion and thrombotic events, respectively. The electronic databases searched included MEDLINE (PubMed), Web of Science, and the Cochrane Central Register of Controlled Trials. Results: Nine RCTs in the qualitative synthesis with a total of 701 patients were included. Results showed a slight increase in in-hospital mortality with FC treatment (RR 1.24, 95% CI 0.64-2.39, p = 0.52) with very low certainty of the evidence. There was no reduction in the use of red blood cells (RBC) transfusion in the first 24 h after admission with FC treatment (mean difference [MD] 0.0 Unit in the FC group, 95% CI - 0.99-0.98, p = 0.99) with very low certainty of the evidence. However, the use of fresh-frozen plasma (FFP) transfusion significantly increased in the first 24 h after admission with FC treatment (MD 2.61 Unit higher in the FC group, 95% CI 0.07-5.16, p = 0.04). The occurrence of thrombotic events did not significantly differ with FC treatment. Conclusions: The present study indicates that the use of FC may result in a slight increase in in-hospital mortality. While FC did not appear to reduce the use of RBC transfusion, it likely increased the use of FFP transfusion and may result in a large increase in platelet concentrate transfusion. However, the results should be interpreted cautiously due to the unbalanced severity in the patient population, high heterogeneity, and risk of bias.
MeSH term(s)	Humans ; Fibrinogen/therapeutic use ; Hemorrhage/drug therapy ; Hemostatics/therapeutic use ; Blood Transfusion ; Elective Surgical Procedures
Chemical Substances	Fibrinogen (9001-32-5) ; Hemostatics
Language	English
Publishing date	2023-03-30
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article
ZDB-ID	2233734-9
ISSN	1749-7922 ; 1749-7922
ISSN (online)	1749-7922
ISSN	1749-7922
DOI	10.1186/s13017-023-00497-5
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Article ; Online: Comparison of metabolic parameters between oral and total parenteral nutrition in children with severe eating disorders.

Suzuki, Yuichi / Itagaki, Shuntaro / Nodera, Maki / Suyama, Kazuhide / Yabe, Hirooki / Hosoya, Mitsuaki

Fukushima journal of medical science

2024

Abstract: Background: This study investigated changes of lipid parameters in children with severe eating disorders during refeeding in order to explore the optimal timing for lipid preparation administration.: Methods: We prospectively assessed the physical ... ...

Abstract	Background: This study investigated changes of lipid parameters in children with severe eating disorders during refeeding in order to explore the optimal timing for lipid preparation administration. Methods: We prospectively assessed the physical conditions of patients with eating disorders after the start of nutrition therapy. The assessments were performed at admission and at 2 and 4 weeks. Lipid metabolism was assessed based on triglyceride (TG), total cholesterol (TC), and free carnitine (FC) levels, as well as acylcarnitine/free carnitine (AC/FC) ratio. Results: A total of 18 patients were included. Of these, 12 and 6 received an oral diet (OD group) and total parenteral nutrition (TPN group), respectively. The mean body mass indexes at hospital admission were 12.8 kg/m Conclusions: Fat-free glucose-based nutrition promoted lipid metabolism over a 2-week period after the start of refeeding, suggesting that balanced energy and lipid intake are essential, even in TPN.
Language	English
Publishing date	2024-03-22
Publishing country	Japan
Document type	Journal Article
ZDB-ID	958255-1
ISSN	2185-4610 ; 0016-2590
ISSN (online)	2185-4610
ISSN	0016-2590
DOI	10.5387/fms.2023_02
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