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  1. Book ; Online: Towards Tokyo 2020: What Will Contribute to Optimal Olympic Athlete Performance?

    Mündel, Toby / Davison, Glen / Soya, Hideaki / Kondo, Narihiko / Barnes, Matthew J.

    2020  

    Keywords Science: general issues ; Physiology ; Exercise Science ; Performance ; Japan ; Olympics
    Size 1 electronic resource (316 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231541
    ISBN 9782889638857 ; 2889638855
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: A case of hyperlipoprotein(a)emia undergoing catheter interventions for coronary artery disease, aortic valve stenosis, and peripheral artery disease.

    Nakamura, Akihiro / Sato, Kenjiro / Kondo, Masateru / Endo, Hideaki

    SAGE open medical case reports

    2022  Volume 10, Page(s) 2050313X221074464

    Abstract: A 79-year-old woman was admitted to our hospital for ischemic necrosis of the right first toe. During having normal lipid profiles, such as low-density lipoprotein cholesterol and triglyceride, plasma levels of lipoprotein(a) (Lp(a)] were abnormally high ...

    Abstract A 79-year-old woman was admitted to our hospital for ischemic necrosis of the right first toe. During having normal lipid profiles, such as low-density lipoprotein cholesterol and triglyceride, plasma levels of lipoprotein(a) (Lp(a)] were abnormally high (141 mg/dL). She had a history of heart failure (HF) due to aortic valve stenosis (AS) and drug-eluting coronary stenting due to angina pectoris. To avoid worsening of HF and limb ischemia during minor amputation, she underwent balloon aortic valvuloplasty and endovascular therapy. She was also placed on proprotein convertase subtilisin/kexin type 9 inhibitors (140 mg of evolocumab) every 2 weeks, which decreased her plasma Lp(a) levels to 105 mg/dL (26% decrease) at discharge. Elevated plasma Lp(a) levels could strongly affect the development of AS and progression of systemic atherosclerosis. The screening and treatment of increased plasma Lp(a) are imperative for patients with AS having peripheral arterial disease.
    Language English
    Publishing date 2022-02-07
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X221074464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: SnO

    Yanagishita, Takashi / Takai, Hideaki / Kondo, Toshiaki / Masuda, Hideki

    Nanotechnology

    2020  Volume 32, Issue 14, Page(s) 145603

    Abstract: ... ...

    Abstract SnO
    Language English
    Publishing date 2020-12-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/abd50a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A case of hyperlipoprotein(a)emia undergoing catheter interventions for coronary artery disease, aortic valve stenosis, and peripheral artery disease

    Akihiro Nakamura / Kenjiro Sato / Masateru Kondo / Hideaki Endo

    SAGE Open Medical Case Reports, Vol

    2022  Volume 10

    Abstract: A 79-year-old woman was admitted to our hospital for ischemic necrosis of the right first toe. During having normal lipid profiles, such as low-density lipoprotein cholesterol and triglyceride, plasma levels of lipoprotein(a) (Lp(a)] were abnormally high ...

    Abstract A 79-year-old woman was admitted to our hospital for ischemic necrosis of the right first toe. During having normal lipid profiles, such as low-density lipoprotein cholesterol and triglyceride, plasma levels of lipoprotein(a) (Lp(a)] were abnormally high (141 mg/dL). She had a history of heart failure (HF) due to aortic valve stenosis (AS) and drug-eluting coronary stenting due to angina pectoris. To avoid worsening of HF and limb ischemia during minor amputation, she underwent balloon aortic valvuloplasty and endovascular therapy. She was also placed on proprotein convertase subtilisin/kexin type 9 inhibitors (140 mg of evolocumab) every 2 weeks, which decreased her plasma Lp(a) levels to 105 mg/dL (26% decrease) at discharge. Elevated plasma Lp(a) levels could strongly affect the development of AS and progression of systemic atherosclerosis. The screening and treatment of increased plasma Lp(a) are imperative for patients with AS having peripheral arterial disease.
    Keywords Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Efficacy and Safety of Pemafibrate Versus Bezafibrate to Treat Patients with Hypertriglyceridemia: A Randomized Crossover Study.

    Nakamura, Akihiro / Kagaya, Yuta / Saito, Hiroki / Kanazawa, Masanori / Sato, Kenjiro / Miura, Masanobu / Kondo, Masateru / Endo, Hideaki

    Journal of atherosclerosis and thrombosis

    2023  Volume 30, Issue 6, Page(s) 698–699

    Language English
    Publishing date 2023-05-02
    Publishing country Japan
    Document type Randomized Controlled Trial ; Journal Article ; Published Erratum
    ZDB-ID 2011474-6
    ISSN 1880-3873 ; 1340-3478
    ISSN (online) 1880-3873
    ISSN 1340-3478
    DOI 10.5551/jat.ER63659
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5192: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Insufficient adenosine-induced hyperemia is a major determinant of discordance between non-hyperemic pressure ratio and fractional flow reserve.

    Matsumoto, Hidenari / Higuchi, Satoshi / Tanaka, Hideaki / Masaki, Ryota / Kondo, Seita / Tsujita, Hiroaki / Shinke, Toshiro

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 729

    Abstract: Adenosine occasionally overestimates fractional flow reserve (FFR) values (i.e., insufficient adenosine-induced hyperemia), leading to low non-hyperemic pressure ratios (NHPR)-high FFR discordance. We investigated the impact of insufficient adenosine- ... ...

    Abstract Adenosine occasionally overestimates fractional flow reserve (FFR) values (i.e., insufficient adenosine-induced hyperemia), leading to low non-hyperemic pressure ratios (NHPR)-high FFR discordance. We investigated the impact of insufficient adenosine-induced hyperemia on NHPR-FFR discordance and the reclassification of functional significance. We measured resting distal-to-aortic pressure ratio (Pd/Pa) and FFR by using adenosine (FFR
    MeSH term(s) Humans ; Adenosine ; Vasodilator Agents ; Fractional Flow Reserve, Myocardial/physiology ; Papaverine ; Coronary Stenosis ; Hyperemia ; Coronary Angiography ; Cardiac Catheterization ; Coronary Vessels ; Predictive Value of Tests ; Severity of Illness Index
    Chemical Substances Adenosine (K72T3FS567) ; Vasodilator Agents ; Papaverine (DAA13NKG2Q)
    Language English
    Publishing date 2023-01-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-27929-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Impact of pemafibrate on lipid profile and insulin resistance in hypertriglyceridemic patients with coronary artery disease and metabolic syndrome.

    Nakamura, Akihiro / Kagaya, Yuta / Saito, Hiroki / Kanazawa, Masanori / Sato, Kenjiro / Miura, Masanobu / Kondo, Masateru / Endo, Hideaki

    Heart and vessels

    2024  

    Abstract: This study examined the effects of pemafibrate, a selective peroxisome proliferator-activated receptor α agonist, on the serum biochemical parameters of male patients with coronary artery disease and metabolic syndrome (MetS). This was a post hoc ... ...

    Abstract This study examined the effects of pemafibrate, a selective peroxisome proliferator-activated receptor α agonist, on the serum biochemical parameters of male patients with coronary artery disease and metabolic syndrome (MetS). This was a post hoc analysis of a randomized, crossover study that treated hypertriglyceridemia with pemafibrate or bezafibrate for 24 weeks, followed by a crossover of another 24 weeks. Of the 60 patients enrolled in the study, 55 were male. Forty-one of 55 male patients were found to have MetS. In this sub-analysis, male patients with MetS (MetS group, n = 41) and those without MetS (non-MetS group, n = 14) were compared. The primary endpoint was a change in fasting serum triglyceride (TG) levels during pemafibrate therapy, and the secondary endpoints were changes in insulin resistance-related markers and liver function parameters. Serum TG levels significantly decreased (MetS group, from 266.6 to 148.0 mg/dL, p < 0.001; non-MetS group, from 203.9 to 97.6 mg/dL, p < 0.001); however, a percent change (%Change) was not significantly different between the groups (- 44.1% vs. - 51.6%, p = 0.084). Serum insulin levels and homeostasis model assessment of insulin resistance significantly decreased in the MetS group but not in the non-MetS group. %Change in liver enzyme levels was markedly decreased in the MetS group compared with that in the non-MetS group (alanine aminotransferase, - 25.1% vs. - 11.3%, p = 0.027; gamma-glutamyl transferase, - 45.8% vs. - 36.2%, p = 0.020). In conclusion, pemafibrate can effectively decrease TG levels in patients with MetS, and it may be a more efficient drug for improving insulin resistance and liver function in such patients.
    Language English
    Publishing date 2024-02-23
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 89678-0
    ISSN 1615-2573 ; 0910-8327 ; 0935-736X
    ISSN (online) 1615-2573
    ISSN 0910-8327 ; 0935-736X
    DOI 10.1007/s00380-024-02363-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2049: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Evaluation of a creatinine clearance correction equation based on body fat mass in older Japanese patients with diabetes.

    Utsumi, Sara / Kondo, Yuki / Harada, Yoshihiko / Yoshida, Akira / Nishimura, Hiroyuki / Narita, Yuki / Irie, Tetsumi / Jinnouchi, Hideaki / Ishitsuka, Yoichi / Hirata, Sumio

    Frontiers in medicine

    2024  Volume 11, Page(s) 1228383

    Abstract: Background: The estimation of creatinine clearance (CCr) in older adult patients with diabetes is subject to deviations from the results of actual measurements because of changes in body composition. In the present study, we aimed to create a correction ...

    Abstract Background: The estimation of creatinine clearance (CCr) in older adult patients with diabetes is subject to deviations from the results of actual measurements because of changes in body composition. In the present study, we aimed to create a correction for the equation used for the estimation of CCr in older adult Asian patients with diabetes using body composition parameters.
    Methods: We enrolled 50 older Japanese patients with diabetes in whom the measured values of CCr were compared with values estimated using the Cockcroft-Gault equation. The relationships between the error in the estimated CCr and body composition parameters were investigated, and the Cockcroft-Gault equation was corrected using the appropriate parameters. To evaluate the generalizability of the corrected equation, the utility of the Cockcroft-Gault equation, which was corrected on the basis of body composition measured using a household body composition meter, was also investigated.
    Results: Body fat mass (BFM) was closely correlated with the error in the estimated CCr. The BFM-corrected Cockcroft-Gault equation was more accurate than the original equation. Similarly, the error became smaller using BFM measured with a household body composition meter.
    Conclusion: The BFM-corrected Cockcroft-Gault equation may provide an accurate method of estimating CCr that can be used in general practice.
    Language English
    Publishing date 2024-02-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2024.1228383
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Fatal case of

    Kondo, Natsuki / Matsumura, Yosuke / Sugiyama, Takuya / Miyahara, Masaya / Imamura, Ai / Kasahara, Yuki / Nagashima, Hideaki / Hanaoka, Noriyuki / Fujiyoshi, Naohiko / Inaba, Shin

    Acute medicine & surgery

    2023  Volume 10, Issue 1, Page(s) e849

    Abstract: Background: Capnocytophaga canimorsus: Case presentation: A healthy 49-year-old man was admitted to the intensive care unit (ICU) for septic shock and AIPF 4 days after a dog bite to his mouth. Computed tomography revealed a small spleen measuring 53  ...

    Abstract Background: Capnocytophaga canimorsus
    Case presentation: A healthy 49-year-old man was admitted to the intensive care unit (ICU) for septic shock and AIPF 4 days after a dog bite to his mouth. Computed tomography revealed a small spleen measuring 53 cm
    Conclusion: Capnocytophaga canimorsus
    Language English
    Publishing date 2023-05-30
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2751184-4
    ISSN 2052-8817 ; 2052-8817
    ISSN (online) 2052-8817
    ISSN 2052-8817
    DOI 10.1002/ams2.849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The impact of sleep-wake problems on health-related quality of life among Japanese nursing college students: a cross sectional survey.

    Adachi, Mai / Nagaura, Yuki / Eto, Hiromi / Kondo, Hideaki / Kato, Chiho

    Health and quality of life outcomes

    2022  Volume 20, Issue 1, Page(s) 150

    Abstract: Aim: This study was conducted to examine the impact of sleep-wake problems on health-related quality of life of Japanese nursing college students.  METHODS: This cross-sectional study was conducted in 2019 on 150 third and fourth-year nursing college ... ...

    Abstract Aim: This study was conducted to examine the impact of sleep-wake problems on health-related quality of life of Japanese nursing college students.  METHODS: This cross-sectional study was conducted in 2019 on 150 third and fourth-year nursing college students from two locations in Japan. Insomnia severity was assessed using the Insomnia Severity Index (ISI) and health-related quality of life using the SF-8 questionnaire. The total sleep time (TST) was divided into 3 groups: < 6 h, 6-7 h (reference), and ≥ 7 h. The total ISI score was divided into 2 groups: ≥ 8 points and < 8 points (reference). Logistic regression analysis was performed to evaluate sleep-wake problems related to decline in mental health.
    Results: The median mental health indicated in the SF-8 questionnaire was divided into two groups, and the factors causing decline in mental health were investigated. The odds ratios (95% confidence interval) for adjusted ISI ≥ 8 and TST on weekdays < 6 h was 6.51 (2.96-14.30) and 3.38 (1.40-8.17), respectively. Mental health status was significantly lower when ISI ≥ 8 and even lower when TST < 6 h.
    Conclusion: Insomnia and short sleep duration are associated with decreased mental health status in nursing college students. Many tended to lack sleep on weekdays. Sleep-wake problems identified while in university should be comprehensively dealt with.
    MeSH term(s) Humans ; Cross-Sectional Studies ; Quality of Life ; Universities ; Sleep Initiation and Maintenance Disorders/epidemiology ; Japan/epidemiology ; Sleep ; Students, Nursing/psychology
    Language English
    Publishing date 2022-11-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2098765-1
    ISSN 1477-7525 ; 1477-7525
    ISSN (online) 1477-7525
    ISSN 1477-7525
    DOI 10.1186/s12955-022-02063-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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