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  1. Article ; Online: Stigma, Bias, and the Shortfalls of Body Mass Index: A Reflection on the State of Weight Management.

    Papademetriou, Marianna / Riehl, Megan / Schulman, Allison R

    The American journal of gastroenterology

    2024  

    Abstract: Obesity is a complex, multifactorial chronic disease. With the development of novel endoscopic techniques and devices for the treatment of obesity, combined with expanding indications for medications, gastroenterologists are more involved in weight ... ...

    Abstract Obesity is a complex, multifactorial chronic disease. With the development of novel endoscopic techniques and devices for the treatment of obesity, combined with expanding indications for medications, gastroenterologists are more involved in weight management than ever before. Despite the modern definition of obesity as a disease, weight bias and stigma are pervasive in the medical community and beyond. These sentiments contribute to worse outcomes for patients. Furthermore, body mass index (BMI), which is the primary metric to define obesity, does not always approximate visceral adiposity in all populations. A weight-centric model of health, which relies on BMI, misclassifies individuals who may be metabolically healthy at elevated weights. This review will summarize the history of BMI, highlight the problems that arise with a weight-centric model of health, and propose alternative weight-inclusive frameworks for assessment and intervention.
    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000002769
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: The face of queenship

    Riehl, Anna

    early modern representations of Elizabeth I

    (Queenship and power)

    2010  

    Abstract: Anna Riehl investigates the aesthetic, political, and gender-related meanings inscribed in Queen ...

    Institution ebrary, Inc
    Author's details Anna Riehl
    Series title Queenship and power
    Abstract Anna Riehl investigates the aesthetic, political, and gender-related meanings inscribed in Queen Elizabeth I's face by her contemporaries
    Keywords Facial expression/Political aspects ; Facial expression/Social aspects ; Monarchy/Public opinion ; Queens/Public opinion ; Great Britain
    Language English
    Size Online-Ressource (xv, 248 p), ill
    Publisher Palgrave Macmillan
    Publishing place New York
    Document type Book ; Online
    Note Includes bibliographical references (p. [209]-238) and index
    ISBN 9780230614956 ; 0230614957
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Article ; Online: Discovery of widely available abyssal rock patches reveals overlooked habitat type and prompts rethinking deep-sea biodiversity.

    Riehl, Torben / Wölfl, Anne-Cathrin / Augustin, Nico / Devey, Colin W / Brandt, Angelika

    Proceedings of the National Academy of Sciences of the United States of America

    2020  Volume 117, Issue 27, Page(s) 15450–15459

    Abstract: Habitat heterogeneity and species diversity are often linked. On the deep seafloor, sediment variability and hard-substrate availability influence geographic patterns of species richness and turnover. The assumption of a generally homogeneous, sedimented ...

    Abstract Habitat heterogeneity and species diversity are often linked. On the deep seafloor, sediment variability and hard-substrate availability influence geographic patterns of species richness and turnover. The assumption of a generally homogeneous, sedimented abyssal seafloor is at odds with the fact that the faunal diversity in some abyssal regions exceeds that of shallow-water environments. Here we show, using a ground-truthed analysis of multibeam sonar data, that the deep seafloor may be much rockier than previously assumed. A combination of bathymetry data, ruggedness, and backscatter from a trans-Atlantic corridor along the Vema Fracture Zone, covering crustal ages from 0 to 100 Ma, show rock exposures occurring at all crustal ages. Extrapolating to the whole Atlantic, over 260,000 km
    MeSH term(s) Acoustics ; Animals ; Aquatic Organisms/physiology ; Atlantic Ocean ; Biodiversity ; Biological Evolution ; Ecological Parameter Monitoring/methods ; Environmental Restoration and Remediation ; Remote Sensing Technology
    Language English
    Publishing date 2020-06-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.1920706117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Single-stranded DNA library preparation from highly degraded DNA using T4 DNA ligase.

    Gansauge, Marie-Theres / Gerber, Tobias / Glocke, Isabelle / Korlevic, Petra / Lippik, Laurin / Nagel, Sarah / Riehl, Lara Maria / Schmidt, Anna / Meyer, Matthias

    Nucleic acids research

    2017  Volume 45, Issue 10, Page(s) e79

    Abstract: DNA library preparation for high-throughput sequencing of genomic DNA usually involves ligation of adapters to double-stranded DNA fragments. However, for highly degraded DNA, especially ancient DNA, library preparation has been found to be more ... ...

    Abstract DNA library preparation for high-throughput sequencing of genomic DNA usually involves ligation of adapters to double-stranded DNA fragments. However, for highly degraded DNA, especially ancient DNA, library preparation has been found to be more efficient if each of the two DNA strands are converted into library molecules separately. We present a new method for single-stranded library preparation, ssDNA2.0, which is based on single-stranded DNA ligation with T4 DNA ligase utilizing a splinter oligonucleotide with a stretch of random bases hybridized to a 3΄ biotinylated donor oligonucleotide. A thorough evaluation of this ligation scheme shows that single-stranded DNA can be ligated to adapter oligonucleotides in higher concentration than with CircLigase (an RNA ligase that was previously chosen for end-to-end ligation in single-stranded library preparation) and that biases in ligation can be minimized when choosing splinters with 7 or 8 random nucleotides. We show that ssDNA2.0 tolerates higher quantities of input DNA than CircLigase-based library preparation, is less costly and better compatible with automation. We also provide an in-depth comparison of library preparation methods on degraded DNA from various sources. Most strikingly, we find that single-stranded library preparation increases library yields from tissues stored in formalin for many years by several orders of magnitude.
    MeSH term(s) Animals ; Bone and Bones/chemistry ; DNA/genetics ; DNA/metabolism ; DNA Ligases/genetics ; DNA Ligases/metabolism ; DNA Primers/chemistry ; DNA Primers/metabolism ; DNA, Single-Stranded/genetics ; DNA, Single-Stranded/metabolism ; Fossils ; Gene Library ; High-Throughput Nucleotide Sequencing ; Horses ; Humans ; Liver/chemistry ; Nucleic Acid Hybridization ; Oligonucleotides/genetics ; Oligonucleotides/metabolism ; Polymerase Chain Reaction ; Sequence Analysis, DNA ; Swine
    Chemical Substances DNA Primers ; DNA, Single-Stranded ; Oligonucleotides ; DNA (9007-49-2) ; DNA Ligases (EC 6.5.1.-)
    Language English
    Publishing date 2017-06-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 186809-3
    ISSN 1362-4962 ; 1362-4954 ; 0301-5610 ; 0305-1048
    ISSN (online) 1362-4962 ; 1362-4954
    ISSN 0301-5610 ; 0305-1048
    DOI 10.1093/nar/gkx033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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