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Book: Xiao ke ji bing shi yu yong yao si lu tan xi

Yang, Shizhe / Zhang, Xianzhe

xian Qin zhi Jin Yuan shi qi = On the disease history and herbal medicine of xiao ke (diabetes) in the pre-Qin to Jin Yuan period

2008

Title variant	On the disease history and herbal medicine of xiao ke (diabetes) in the pre-Qin to Jin Yuan period
Author's details	Yang Shizhe, Zhang Xianzhe zhu
MeSH term(s)	Diabetes Mellitus/history ; Herbal Medicine/history ; Medicine, Chinese Traditional/history ; History, Ancient ; History, Medieval
Keywords	China
Language	Chinese
Size	x, 508 p. :, ill. ;, 26 cm.
Edition	Di 1 ban.
Publisher	Guo li Zhongguo yi yao yan jiu suo
Publishing place	Taibei Shi
Document type	Book
ISBN	9789860164107 ; 986016410X
Database	Catalogue of the US National Library of Medicine (NLM)

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Book: Guang dian ji ban dao ti gao ke ji chan ye lao gong shen pu lu jian kang wei hai ping gu yan jiu

Yang, Qixian

Health effect assessment of arsenic exposure for workers in electro-optics and semiconductor high-tech industries

(Lao gong an quan wei sheng yan jiu bao gao)

2013

Title variant	Health effect assessment of arsenic exposure for workers in electro-optics and semiconductor high-tech industries
Author's details	yan jiu zhu chi ren Yang Qixian, Mao Yifang
Series title	Lao gong an quan wei sheng yan jiu bao gao
MeSH term(s)	Arsenic/toxicity ; Occupational Exposure/adverse effects
Keywords	Taiwan
Language	Chinese ; English
Size	ix, 69 pages :, illustrations.
Edition	1 ban.
Document type	Book
Note	Abstract also in English.
ISBN	9789860366815 ; 9860366810
Database	Catalogue of the US National Library of Medicine (NLM)

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Article ; Online: Analysis of an environmental epidemic model based on voluntary vaccination policy.

Li, Ke-Lu / Yang, Jun-Yuan / Li, Xue-Zhi

Computer methods in biomechanics and biomedical engineering

2022 Volume 26, Issue 5, Page(s) 595–611

Abstract: With the worsening of the environment and the increasing international trade, indirect transmission from exposure to contaminants in the surrounding environment has become an overlooked mode of transmission. This paper proposes a new game-theoretic model ...

Abstract	With the worsening of the environment and the increasing international trade, indirect transmission from exposure to contaminants in the surrounding environment has become an overlooked mode of transmission. This paper proposes a new game-theoretic model considering voluntary vaccination against imperfection and the unique integration of human-to-human and virus-to-human transmission routes. Based on the individual-based risk assessment update rule (IB-RA), the strategy-based risk assessment update rule (SB-RA), and the direct commitment update rule (DC), the different effects of individuals' behaviors on disease prevalence are analyzed. To find the effect of indirect transmission on epidemic transmission, we compare our model with the traditional SVIR model. Finally, it can be seen that indirect transmission mechanisms will aggravate the spread of epidemics.
MeSH term(s)	Humans ; Commerce ; Game Theory ; Internationality ; Vaccination ; Epidemics/prevention & control
Language	English
Publishing date	2022-05-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2071764-7
ISSN	1476-8259 ; 1025-5842
ISSN (online)	1476-8259
ISSN	1025-5842
DOI	10.1080/10255842.2022.2079080
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Role of exosomes in the pathogenesis of inflammation in Parkinson's disease.

Li, Ke-Lu / Huang, Hong-Yan / Ren, Hui / Yang, Xing-Long

Neural regeneration research

2022 Volume 17, Issue 9, Page(s) 1898–1906

Abstract: Inflammatory responses, including glial cell activation and peripheral immune cell infiltration, are involved in the pathogenesis of Parkinson's disease (PD). These inflammatory responses appear to be closely related to the release of extracellular ... ...

Abstract	Inflammatory responses, including glial cell activation and peripheral immune cell infiltration, are involved in the pathogenesis of Parkinson's disease (PD). These inflammatory responses appear to be closely related to the release of extracellular vesicles, such as exosomes. However, the relationships among different forms of glial cell activation, synuclein dysregulation, mitochondrial dysfunction, and exosomes are complicated. This review discusses the multiple roles played by exosomes in PD-associated inflammation and concludes that exosomes can transport toxic α-synuclein oligomers to immature neurons and into the extracellular environment, inducing the oligomerization of α-synuclein in normal neurons. Misfolded α-synuclein causes microglia and astrocytes to activate and secrete exosomes. Glial cell-derived exosomes participate in communications between glial cells and neurons, triggering anti-stress and anti-inflammatory responses, in addition to axon growth. The production and release of mitochondrial vesicles and exosomes establish a new mechanism for linking mitochondrial dysfunction to systemic inflammation associated with PD. Given the relevance of exosomes as mediators of neuron-glia communication in neuroinflammation and neuropathogenesis, new targeted treatment strategies are currently being developed that use these types of extracellular vesicles as drug carriers. Exosome-mediated inflammation may be a promising target for intervention in PD patients.
Language	English
Publishing date	2022-02-10
Publishing country	India
Document type	Journal Article ; Review
ZDB-ID	2388460-5
ISSN	1876-7958 ; 1673-5374
ISSN (online)	1876-7958
ISSN	1673-5374
DOI	10.4103/1673-5374.335143
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Preventive strategies for low anterior resection syndrome

Yang Li / Quan Wang / Xin-Yu Zhang / Ke-Lu Yang / Xiao-Nan Liu / Rui-Shu Li / Shi-Qi Wang

BMJ Open, Vol 13, Iss

a protocol for systematic review and evidence mapping

2023 Volume 12

Abstract: Introduction Rectal cancer is one of the top 10 cancers worldwide. Up to 80% of patients with rectal tumours have had sphincter-saving surgery, mainly due to the large expectation of anal preservation. However, patients tend to experience low anterior ... ...

Abstract	Introduction Rectal cancer is one of the top 10 cancers worldwide. Up to 80% of patients with rectal tumours have had sphincter-saving surgery, mainly due to the large expectation of anal preservation. However, patients tend to experience low anterior resection syndrome (LARS) after rectal resection, which is disordered bowel function that includes faecal incontinence, urgency, frequent defecation, constipation and evacuation difficulties. LARS, with an estimated prevalence of 41%, has been reported to substantially decrease the quality of life of patients. However, no comprehensive preventive strategies are currently available for LARS. This systematic review aims to synthesise evidence on the current LARS preventive strategies.Methods and analysis This protocol is reported according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) checklist. Literature in PubMed (via Medline), Embase and the Cochrane Library from inception to July 2023 will be searched to identify articles relevant to preventive effectiveness against LARS. The Cochrane Collaboration’s risk of bias tool for randomised controlled trials and the Newcastle-Ottawa Scale for clinical controlled trials, cohort studies and case–control studies will be used to assess the risk of bias. We will group the included studies by the type of LARS prevention strategy and present an overview of the main findings in the form of evidence mapping. A meta-analysis is planned if there is no substantial clinical heterogeneity between the included studies. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) will be used to evaluate the quality of the evidence.Ethics and dissemination Ethical approval is not needed for systematic review of published data. The findings will be published in a peer-reviewed journal and disseminated at scientific conferences.PROSPERO registration number CRD42023402886.
Keywords	Medicine ; R
Subject code	610
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	BMJ Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Consistency assessment and visualization of recommendations on gastroesophageal reflux disease: a scoping review of clinical practice guidelines.

Zhang, Xin-Yu / Yang, Ke-Lu / Wang, Shi-Qi / Li, Yang / Li, Rui-Shu / Jiang, Ke-Wei / Liu, Xiao-Nan / Wang, Quan

Polish archives of internal medicine

2023 Volume 133, Issue 11

Abstract: Introduction: Gastroesophageal reflux disease (GERD) is a highly prevalent gastrointestinal disorder that causes diverse esophageal and extraesophageal symptoms. Many clinical practice guidelines (CPGs) have been issued around the world to provide ... ...

Abstract	Introduction: Gastroesophageal reflux disease (GERD) is a highly prevalent gastrointestinal disorder that causes diverse esophageal and extraesophageal symptoms. Many clinical practice guidelines (CPGs) have been issued around the world to provide practical evidence regarding GERD management. However, some of the recommendations discussed in various CPGs are inconsistent across individual documents. Objectives: We aimed to summarize the evidence from CPGs on GERD and assess the consistency of the recommendations. Patients and methods: In this scoping review, we identified current CPGs on the clinical management of GERD, which were comprehensively searched for in electronic databases and on relevant scientific websites. The recommendations were extracted using the population‑intervention‑comparison framework and were subsequently categorized into tables. Results: Ultimately, 24 CPGs were identified. They included 86 recommendations, which were classified into 5 categories: definition, epidemiology, diagnosis, treatment, and complications. Among the identified recommendations, 68 were proposed in at least 2 CPGs, and they were assessed for the consistency of direction and strength. Overall, 32.4% of the recommendations (22/68) were consistent in direction and strength, whereas 60.3% (41/68) were consistent in direction but inconsistent in strength. Moreover, 7.4% (5/68) were inconsistent in direction. These referred to the relationship between GERD and tobacco consumption, Helicobacter pylori infection, diagnostic utility of the 2‑week proton pump inhibitor test, cessation of special food, and antireflux surgery for GERD with extraesophageal symptoms. Conclusions: Most CPG recommendations regarding GERD were consistent in direction, except for 5 discrepancies, for which further well‑designed, large‑scale research is required to explain the inconsistency.
MeSH term(s)	Humans ; Gastroesophageal Reflux/diagnosis ; Gastroesophageal Reflux/therapy ; Gastroesophageal Reflux/complications ; Helicobacter Infections/diagnosis ; Helicobacter Infections/drug therapy ; Helicobacter Infections/complications ; Helicobacter pylori ; Proton Pump Inhibitors ; Practice Guidelines as Topic
Chemical Substances	Proton Pump Inhibitors
Language	English
Publishing date	2023-05-04
Publishing country	Poland
Document type	Review ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	123500-x
ISSN	1897-9483 ; 0032-3772
ISSN (online)	1897-9483
ISSN	0032-3772
DOI	10.20452/pamw.16490
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Preventive strategies of cancer therapeutics-related cardiotoxicity in childhood cancer survivors: a protocol of systematic review.

Zhang, Xin-Yu / Wang, Quan / Yang, Ke-Lu / Wei, Dang / Liu, Xiao-Nan

BMJ open

2022 Volume 12, Issue 9, Page(s) e065776

Abstract: Introduction: Five-year survival in childhood cancer has been improved markedly in the past decades. Childhood cancer survivors are at high risk of cardiovascular diseases due to anticancer therapy-induced cardiotoxicity. The comprehensive evidence for ... ...

Abstract	Introduction: Five-year survival in childhood cancer has been improved markedly in the past decades. Childhood cancer survivors are at high risk of cardiovascular diseases due to anticancer therapy-induced cardiotoxicity. The comprehensive evidence for the prevention of anticancer therapy-induced cardiovascular disease is, however, sparse. The systematic review described in the protocol aims to summarise the effect of current prevention for anticancer therapy-induced cardiotoxicity among childhood cancer survivors. Methods and analysis: This protocol is reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols checklist. We will search PubMed (via Medline), Embase and the Cochrane Library and include the studies investigating the effect of prevention against anticancer therapy-induced cardiotoxicity of childhood cancer. To assess the risk of bias, we will use the Cochrane Collaboration's risk of bias tool for randomised control trials and the Newcastle-Ottawa Scale for cohort studies and case-control studies. Furthermore, we will conduct meta-analyses if there is no substantial clinical heterogeneity between included studies. The Grading of Recommendations, Assessment, Development and Evaluation will be used to evaluate the quality of evidence. Ethics and dissemination: Ethical approval is not needed for systematic review of published data. The findings will be published in a peer-reviewed journal and disseminated at scientific conferences. Prospero registration number: CRD42022333877.
MeSH term(s)	Cancer Survivors ; Cardiotoxicity/etiology ; Cardiotoxicity/prevention & control ; Cardiovascular Diseases ; Case-Control Studies ; Child ; Humans ; Neoplasms/drug therapy ; Research Design ; Systematic Reviews as Topic
Language	English
Publishing date	2022-09-20
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2022-065776
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effectiveness, Safety, and Tolerance of Scalp Cooling for Chemotherapy-Induced Alopecia.

Zhang, Xin-Yu / Yang, Ke-Lu / Liu, Wen-Qing / Huang, Jie / Ning, Ning

Oncology nursing forum

2022 Volume 49, Issue 4, Page(s) 369–384

Abstract: Problem identification: There is a lack of guideline recommendations about the use of scalp cooling for preventing chemotherapy-induced alopecia (CIA). This overview was conducted to summarize effectiveness, safety, and tolerance of scalp cooling for ... ...

Abstract	Problem identification: There is a lack of guideline recommendations about the use of scalp cooling for preventing chemotherapy-induced alopecia (CIA). This overview was conducted to summarize effectiveness, safety, and tolerance of scalp cooling for CIA based on systematic reviews. Literature search: PubMed®, Embase®, Cochrane Library, and CNKI were searched from inception to May 15, 2021. Data evaluation: AMSTAR 2 was used to assess the methodologic quality. Qualitative and quantitative synthesis methods were used to identify the effectiveness, safety, and tolerance of scalp cooling. Synthesis: 14 systematic reviews were identified, and the quality assessment was poor. Scalp cooling has been considered to be effective for preventing chemotherapy-induced alopecia and has been confirmed in patients with breast cancer and other solid tumors. Most adverse effects were mild and moderate, and scalp cooling did not increase the risk of scalp metastases. Implications for research: This overview could guide nurses to provide access to scalp cooling to reduce the risk of severe or total chemotherapy-induced alopecia for patients undergoing chemotherapy. The large-scale application of scalp cooling may be promoted by establishing reimbursement mechanisms and increasing available devices in the future.
MeSH term(s)	Alopecia/chemically induced ; Alopecia/drug therapy ; Alopecia/prevention & control ; Antineoplastic Agents/adverse effects ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Female ; Humans ; Scalp/pathology
Chemical Substances	Antineoplastic Agents
Language	English
Publishing date	2022-07-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	604886-9
ISSN	1538-0688 ; 0190-535X ; 1538-0688
ISSN (online)	1538-0688 ; 0190-535X
ISSN	1538-0688
DOI	10.1188/22.ONF.369-384
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Preventive strategies for low anterior resection syndrome: a protocol for systematic review and evidence mapping.

Zhang, Xin-Yu / Yang, Ke-Lu / Li, Yang / Li, Rui-Shu / Wang, Shi-Qi / Liu, Xiao-Nan / Wang, Quan

BMJ open

2023 Volume 13, Issue 12, Page(s) e077279

Abstract: Introduction: Rectal cancer is one of the top 10 cancers worldwide. Up to 80% of patients with rectal tumours have had sphincter-saving surgery, mainly due to the large expectation of anal preservation. However, patients tend to experience low anterior ... ...

Abstract	Introduction: Rectal cancer is one of the top 10 cancers worldwide. Up to 80% of patients with rectal tumours have had sphincter-saving surgery, mainly due to the large expectation of anal preservation. However, patients tend to experience low anterior resection syndrome (LARS) after rectal resection, which is disordered bowel function that includes faecal incontinence, urgency, frequent defecation, constipation and evacuation difficulties. LARS, with an estimated prevalence of 41%, has been reported to substantially decrease the quality of life of patients. However, no comprehensive preventive strategies are currently available for LARS. This systematic review aims to synthesise evidence on the current LARS preventive strategies. Methods and analysis: This protocol is reported according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) checklist. Literature in PubMed (via Medline), Embase and the Cochrane Library from inception to July 2023 will be searched to identify articles relevant to preventive effectiveness against LARS. The Cochrane Collaboration's risk of bias tool for randomised controlled trials and the Newcastle-Ottawa Scale for clinical controlled trials, cohort studies and case-control studies will be used to assess the risk of bias. We will group the included studies by the type of LARS prevention strategy and present an overview of the main findings in the form of evidence mapping. A meta-analysis is planned if there is no substantial clinical heterogeneity between the included studies. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) will be used to evaluate the quality of the evidence. Ethics and dissemination: Ethical approval is not needed for systematic review of published data. The findings will be published in a peer-reviewed journal and disseminated at scientific conferences. Prospero registration number: CRD42023402886.
MeSH term(s)	Humans ; Low Anterior Resection Syndrome ; Rectal Neoplasms/surgery ; Postoperative Complications/prevention & control ; Quality of Life ; Systematic Reviews as Topic ; Meta-Analysis as Topic
Language	English
Publishing date	2023-12-01
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-077279
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Association between preoperative anxiety and postoperative delirium in older patients: a systematic review and meta-analysis.

Yang, Ke-Lu / Detroyer, Elke / Van Grootven, Bastiaan / Tuand, Krizia / Zhao, Dan-Ni / Rex, Steffen / Milisen, Koen

BMC geriatrics

2023 Volume 23, Issue 1, Page(s) 198

Abstract: Background: Postoperative delirium (POD) is a common postoperative complication associated with multiple adverse consequences on patient outcomes and higher medical expenses. Preoperative anxiety has been suggested as a possible precipitating factor for ...

Abstract	Background: Postoperative delirium (POD) is a common postoperative complication associated with multiple adverse consequences on patient outcomes and higher medical expenses. Preoperative anxiety has been suggested as a possible precipitating factor for the development of POD. As such, we aimed to explore the association between preoperative anxiety and POD in older surgical patients. Methods: Electronic databases including MEDLINE (via PubMed), EMBASE (via Embase.com), Web of Science Core Collection, Cumulative Index to Nursing and Allied Health Literature (CINAHL Complete; via EBSCOhost) and clinical trial registries were systematically searched to identify prospective studies examining preoperative anxiety as a risk factor for POD in older surgical patients. We used Joanna Briggs Institute Critical Appraisal Checklist for Cohort Studies to assess the quality of included studies. The association between preoperative anxiety and POD was summarized with odds ratios (ORs) and 95% confidence intervals (CIs) using DerSimonian-Laird random-effects meta-analysis. Results: Eleven studies were included (1691 participants; mean age ranging between 63.1-82.3 years). Five studies used a theoretical definition for preoperative anxiety, with the Anxiety subscale of Hospital Anxiety and Depression Scale (HADS-A) as the instrument being most often used. When using dichotomized measures and within the HADS-A subgroup analysis, preoperative anxiety was significantly associated with POD (OR = 2.17, 95%CI: 1.01-4.68, I Conclusions: An unclear association between preoperative anxiety and POD in older surgical patients was found in our study. Given the ambiguity in conceptualization and measurement instruments used for preoperative anxiety, more research is warranted in which a greater emphasis should be placed on how preoperative anxiety is operationalized and measured.
MeSH term(s)	Humans ; Aged ; Aged, 80 and over ; Emergence Delirium ; Delirium/diagnosis ; Delirium/epidemiology ; Delirium/etiology ; Prospective Studies ; Anxiety/diagnosis ; Postoperative Complications/diagnosis ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Risk Factors
Language	English
Publishing date	2023-03-30
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2059865-8
ISSN	1471-2318 ; 1471-2318
ISSN (online)	1471-2318
ISSN	1471-2318
DOI	10.1186/s12877-023-03923-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

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