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  1. Article ; Online: [Alice in Wonderland and anti-vaccine misinformation].

    Briem, Haraldur

    Laeknabladid

    2022  Volume 108, Issue 2, Page(s) 67

    MeSH term(s) Communication ; Humans
    Language Icelandic
    Publishing date 2022-02-01
    Publishing country Iceland
    Document type Editorial
    ZDB-ID 806661-9
    ISSN 1670-4959 ; 0023-7213
    ISSN (online) 1670-4959
    ISSN 0023-7213
    DOI 10.17992/lbl.2022.02.673
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  2. Article ; Online: [COVID-19. The only certainty is the uncertainty].

    Briem, Haraldur

    Laeknabladid

    2020  Volume 106, Issue 3, Page(s) 119

    MeSH term(s) COVID-19 ; China/epidemiology ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Humans ; Iceland/epidemiology ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Uncertainty
    Keywords covid19
    Language Icelandic
    Publishing date 2020-03-12
    Publishing country Iceland
    Document type Editorial
    ZDB-ID 806661-9
    ISSN 1670-4959 ; 0023-7213
    ISSN (online) 1670-4959
    ISSN 0023-7213
    DOI 10.17992/lbl.2020.03.469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Boys demonstrate greater knee frontal moments than girls during the impact phase of cutting maneuvers, despite age-related increases in girls.

    Ghasemi, Mohammadhossein / Sigurðsson, Haraldur Björn / Sveinsson, Þórarinn / Briem, Kristín

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

    2023  Volume 31, Issue 5, Page(s) 1833–1839

    Abstract: Purpose: Anterior cruciate ligament (ACL) injury rate is low among children, but increases during adolescence, especially in girls. Increases in the knee valgus moment within 70 ms of contact with the ground (KFM: Methods: Kinematic and kinetic data ... ...

    Abstract Purpose: Anterior cruciate ligament (ACL) injury rate is low among children, but increases during adolescence, especially in girls. Increases in the knee valgus moment within 70 ms of contact with the ground (KFM
    Methods: Kinematic and kinetic data during the CM task, performed before and after physical exertion, were recorded using a motion capture system and a force plate. A total of 293 team handball and soccer players, aged 9-12 years, were recruited. A number of those who continued sports participation (n = 103) returned five years later to repeat the test procedure. Three mixed-model analysis of variance (ANOVA) for repeated measures tests were used to determine the effects of sex and age period on the KFM
    Results: Boys had significantly higher KFM
    Conclusion: Although the marked increase in KFM
    Level of evidence: II.
    MeSH term(s) Male ; Female ; Adolescent ; Child ; Humans ; Knee Joint ; Knee ; Lower Extremity ; Anterior Cruciate Ligament Injuries/etiology ; Knee Injuries/complications
    Language English
    Publishing date 2023-02-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1159064-6
    ISSN 1433-7347 ; 0942-2056
    ISSN (online) 1433-7347
    ISSN 0942-2056
    DOI 10.1007/s00167-023-07340-z
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  5. Article: Cluster analysis successfully identifies clinically meaningful knee valgus moment patterns: frequency of early peaks reflects sex-specific ACL injury incidence.

    Sigurðsson, Haraldur B / Briem, Kristín

    Journal of experimental orthopaedics

    2019  Volume 6, Issue 1, Page(s) 37

    Abstract: Background: Biomechanical studies of ACL injury risk factors frequently analyze only a fraction of the relevant data, and typically not in accordance with the injury mechanism. Extracting a peak value within a time series of relevance to ACL injuries is ...

    Abstract Background: Biomechanical studies of ACL injury risk factors frequently analyze only a fraction of the relevant data, and typically not in accordance with the injury mechanism. Extracting a peak value within a time series of relevance to ACL injuries is challenging due to differences in the relative timing and size of the peak value of interest.
    Aims/hypotheses: The aim was to cluster analyze the knee valgus moment time series curve shape in the early stance phase. We hypothesized that 1a) There would be few discrete curve shapes, 1b) there would be a shape reflecting an early peak of the knee valgus moment, 2a) youth athletes of both sexes would show similar frequencies of early peaks, 2b) adolescent girls would have greater early peak frequencies.
    Methods: N = 213 (39% boys) youth soccer and team handball athletes (phase 1) and N = 35 (45% boys) with 5 year follow-up data (phase 2) were recorded performing a change of direction task with 3D motion analysis and a force plate. The time series of the first 30% of stance phase were cluster analyzed based on Euclidean distances in two steps; shape-based main clusters with a transformed time series, and magnitude based sub-clusters with body weight normalized time series. Group differences (sex, phase) in curve shape frequencies, and shape-magnitude frequencies were tested with chi-squared tests.
    Results: Six discrete shape-clusters and 14 magnitude based sub-clusters were formed. Phase 1 boys had greater frequency of early peaks than phase 1 girls (38% vs 25% respectively, P <  0.001 for full test). Phase 2 girls had greater frequency of early peaks than phase 2 boys (42% vs 21% respectively, P <  0.001 for full test).
    Conclusions: Cluster analysis can reveal different patterns of curve shapes in biomechanical data, which likely reflect different movement strategies. The early peak shape is relatable to the ACL injury mechanism as the timing of its peak moment is consistent with the timing of injury. Greater frequency of early peaks demonstrated by Phase 2 girls is consistent with their higher risk of ACL injury in sports.
    Language English
    Publishing date 2019-08-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2780021-0
    ISSN 2197-1153
    ISSN 2197-1153
    DOI 10.1186/s40634-019-0205-5
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  6. Article: Don't Peak Too Early: Evidence for an ACL Injury Prevention Mechanism of the 11+ Program.

    Sigurðsson, Haraldur B / Briem, Kristín / Grävare Silbernagel, Karin / Snyder-Mackler, Lynn

    International journal of sports physical therapy

    2022  Volume 17, Issue 5, Page(s) 823–831

    Abstract: Background: The 11+ program prevents anterior cruciate ligament (ACL) injuries in athletes through unknown mechanisms.: Purpose: The aim of the current study was to evaluate the effects of The 11+ intervention program, performed by female soccer ... ...

    Abstract Background: The 11+ program prevents anterior cruciate ligament (ACL) injuries in athletes through unknown mechanisms.
    Purpose: The aim of the current study was to evaluate the effects of The 11+ intervention program, performed by female soccer players during a single season, on the frequency of Early Peaks during athletic tasks.
    Methods: Three teams (69 players) of collegiate female soccer athletes (Divisions I and II) were recruited. Two teams (49 players) volunteered to perform The 11+ three times per week for one season (~22 weeks plus three weeks pre-season), and one team (20 players) served as controls. The athletes performed three repetitions of a cutting maneuver, side shuffle direction change, and forwards to backwards running direction change before and after the competitive season and were recorded using marker-based 3D motion capture. Knee valgus moment time series were calculated for each repetition with inverse kinematics and classified as either "Very Early Peak", "Early Peak" or "other" using cluster analysis. The classification was based timing of the peak relative to the timing of ACL injuries. The effect of the intervention on the frequency of Very Early Peaks and Early Peaks was evaluated with a mixed Poisson regression controlling for the movement task and pre-season frequency.
    Results: The 11+ intervention reduced the frequency of Early Peak knee valgus moment in one intervention team (coefficient = -1.16, p = 0.004), but not the other (coefficient = -0.01, p = 0.977). No effect was observed on the frequency of Very Early Peak knee valgus moment.
    Conclusions: Reduced frequency of knee valgus moment Early Peak during athletic tasks may explain the mechanism by which The 11+ program decreases risk of ACL injury. Prospective studies with a much larger sample size are required to establish a link between Early Peak knee valgus moments and risk of ACL injury.
    Level of evidence: 2b.
    Language English
    Publishing date 2022-08-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2628664-6
    ISSN 2159-2896
    ISSN 2159-2896
    DOI 10.26603/001c.36524
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Thesis: Cerebrospinal fluid in patients with meningitis and encephalitis

    BRIEM, HARALDUR

    diagnostic and prognostic significance of concentrations of lactate, total amino acids, and hypoxanthine and creatine kinase isoenzyme BB activity

    1982  

    Size getr. Zaehlung : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Stockholm, Univ., Diss., 1982
    HBZ-ID HT002663202
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    83 E 1178 order for loan Magazin

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  8. Article ; Online: Combined Effects of External Moments and Muscle Activations on ACL Loading during Numerical Simulations of a Female Model in OpenSim

    Oliver J. Daliet / Kristín Briem / Sigurður Brynjólfsson / Haraldur B. Sigurðsson

    Applied Sciences, Vol 11, Iss 11971, p

    2021  Volume 11971

    Abstract: Background: Anterior cruciate ligament (ACL) injuries have been studied using a variety of methods and tools. However, each is hindered by specific limitations with respect to its application. Aim: To assess the combined effects of external moments and ... ...

    Abstract Background: Anterior cruciate ligament (ACL) injuries have been studied using a variety of methods and tools. However, each is hindered by specific limitations with respect to its application. Aim: To assess the combined effects of external moments and muscle activations on ACL loading using serial, forward dynamics (FD) simulations of single leg, hyperextension landings in OpenSim. Methods: The FD tool of OpenSim was iteratively run using different combinations of knee-spanning muscle activation levels, internal rotation and valgus knee moment magnitudes. A regression was conducted on the data in order to predict ACL loading under different conditions. Results: A purely abduction moment leads to greater mean ACL loading than a purely internal rotation moment or any combination of the two. Additionally, the generalized boosted regression model using both external moments and certain knee muscles identified the internal rotation moment as the most important variable in predicting the ACL load (R 2 = 0.9; p < 0.0001). Conclusion: This study demonstrated a novel and practical application of an OpenSim musculoskeletal model that supports the ACL injury mechanism of landing with low knee flexion angles, high muscle forces of the Quadriceps muscles and an external knee valgus moment, though further investigation is needed.
    Keywords knee joint ; biomechanics ; motion analysis ; computer simulations ; in silico ; injury mechanism ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 796
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Don’t Peak Too Early

    Haraldur B Sigurðsson / Kristín Briem / Karin Grävare Silbernagel / Lynn Snyder-Mackler

    International Journal of Sports Physical Therapy, Vol 17, Iss

    Evidence for an ACL Injury Prevention Mechanism of the 11+ Program

    2022  Volume 5

    Abstract: Background The 11+ program prevents anterior cruciate ligament (ACL) injuries in athletes through unknown mechanisms. # Purpose The aim of the current study was to evaluate the effects of The 11+ intervention program, performed by female soccer players ...

    Abstract # Background The 11+ program prevents anterior cruciate ligament (ACL) injuries in athletes through unknown mechanisms. # Purpose The aim of the current study was to evaluate the effects of The 11+ intervention program, performed by female soccer players during a single season, on the frequency of Early Peaks during athletic tasks. # Methods Three teams (69 players) of collegiate female soccer athletes (Divisions I and II) were recruited. Two teams (49 players) volunteered to perform The 11+ three times per week for one season (~22 weeks plus three weeks pre-season), and one team (20 players) served as controls. The athletes performed three repetitions of a cutting maneuver, side shuffle direction change, and forwards to backwards running direction change before and after the competitive season and were recorded using marker-based 3D motion capture. Knee valgus moment time series were calculated for each repetition with inverse kinematics and classified as either “Very Early Peak”, “Early Peak” or “other” using cluster analysis. The classification was based timing of the peak relative to the timing of ACL injuries. The effect of the intervention on the frequency of Very Early Peaks and Early Peaks was evaluated with a mixed Poisson regression controlling for the movement task and pre-season frequency. # Results The 11+ intervention reduced the frequency of Early Peak knee valgus moment in one intervention team (coefficient = -1.16, p = 0.004), but not the other (coefficient = -0.01, p = 0.977). No effect was observed on the frequency of Very Early Peak knee valgus moment. # Conclusions Reduced frequency of knee valgus moment Early Peak during athletic tasks may explain the mechanism by which The 11+ program decreases risk of ACL injury. Prospective studies with a much larger sample size are required to establish a link between Early Peak knee valgus moments and risk of ACL injury. # Level of evidence 2b
    Keywords Sports medicine ; RC1200-1245
    Subject code 796
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher North American Sports Medicine Institute
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Laerdómar dregnir af spaensku veikinni 1918.

    Briem, Haraldur

    Laeknabladid

    2008  Volume 94, Issue 11, Page(s) 721

    Title translation The Spanish flu in Iceland in 1918. Lessons learned.
    MeSH term(s) Disease Outbreaks/history ; History, 20th Century ; Humans ; Iceland ; Influenza, Human/history
    Language Icelandic
    Publishing date 2008-11
    Publishing country Iceland
    Document type Comment ; Editorial ; Historical Article
    ZDB-ID 806661-9
    ISSN 1670-4959 ; 0023-7213
    ISSN (online) 1670-4959
    ISSN 0023-7213
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