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  1. Article ; Online: Preoperative diagnostic criteria for scleroatrophic gallbladder: A systematic review protocol.

    Bessa-Melo, Renato / Fernandes, Cristina / Aguiar, Ana / Lopez-Ben, Santiago / Guimarães, Luís / Serralheiro, Pedro

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0300336

    Abstract: Background: Although scleroatrophic gallbladder is a rare condition, it presents significant clinical challenges in diagnosis and management. More agreement is needed on this disorder's diagnostic criteria and optimal management approach. We will ... ...

    Abstract Background: Although scleroatrophic gallbladder is a rare condition, it presents significant clinical challenges in diagnosis and management. More agreement is needed on this disorder's diagnostic criteria and optimal management approach. We will conduct a systematic review to summarise the scleroatrophic gallbladder's preoperative diagnostic criteria, including imaging modalities.
    Methods: A systematic review will be undertaken using the PRISMA guidelines. The protocol has been registered in PROSPERO (CRD42024503701). We will search in Medline (via PubMed), Embase, SCOPUS, the Cochrane Library, and Web of Science to find original studies reporting about scleroatrophic gallbladder or synonymous. Two reviewers will independently screen the titles and abstracts following the eligibility criteria. We will include all types of studies that describe any diagnostic criteria or tools. After retrieving the full text of the selected studies, we will conduct a standardised data extraction. Finally, a narrative synthesis will be performed. The quality of the identified studies will be assessed using the Quality Assessment of Diagnostic Accuracy Studies- 2 tool.
    Discussion: This systematic review will provide information on the preoperative diagnostic criteria of the scleroatrophic gallbladder and the value of imaging studies in its diagnosis. In addition, this work will aid doctors in the decision-making process for diagnosing scleroatrophic gallbladder and propose treatment approaches to this condition.
    Systematic review registration: The protocol has been registered in PROSPERO (CRD42024503701).
    MeSH term(s) Gallbladder/diagnostic imaging ; Gallbladder/surgery ; Systematic Reviews as Topic ; MEDLINE
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0300336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: [COVID-19 and the Invisible Damage].

    Melo, Renato Bessa / Tavares, Nuno Teixeira / Duarte, Raquel

    Acta medica portuguesa

    2020  Volume 33, Issue 5, Page(s) 293–294

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language Portuguese
    Publishing date 2020-04-13
    Publishing country Portugal
    Document type Editorial
    ZDB-ID 603078-6
    ISSN 1646-0758 ; 0870-399X
    ISSN (online) 1646-0758
    ISSN 0870-399X
    DOI 10.20344/amp.13911
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2343: Show issues Location:
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  3. Article ; Online: A framework model to integrate sources and pathways in the assessment of river water pollution.

    Bessa Santos, Regina Maria / Farias do Valle Junior, Renato / Abreu Pires de Melo Silva, Maytê Maria / Tarlé Pissarra, Teresa Cristina / Carvalho de Melo, Marília / Valera, Carlos Alberto / Leal Pacheco, Fernando António / Sanches Fernandes, Luís Filipe

    Environmental pollution (Barking, Essex : 1987)

    2024  Volume 347, Page(s) 123661

    Abstract: Metal and nutrient pollution, soil erosion, and alterations in climate and hydrology are prevalent issues that impact the water quality of riverine systems. However, integrated approaches to assess and isolate causes and paths of river water pollution ... ...

    Abstract Metal and nutrient pollution, soil erosion, and alterations in climate and hydrology are prevalent issues that impact the water quality of riverine systems. However, integrated approaches to assess and isolate causes and paths of river water pollution are scarce, especially in the case of watersheds impacted by multiple hazardous activities. Therefore, a framework model for investigating the multiple sources of river water pollution was developed. The chosen study area was the Paraopeba River basin located in the Minas Gerais, Brazil. Besides multiple agriculture, industrial, and urban pollution sources, this region was profoundly affected by the rupture of the B1 tailings dam (in January 2019) at the Córrego do Feijão mine, resulting in the release of metal-rich waste. Considering this situation, thirty-nine physicochemical and hydromorphological parameters were examined in the Paraopeba River basin, in the 2019-2023 period. The analysis involved various statistical techniques, including bivariate and multivariate methods such as correlation analysis, principal component analysis, and clustering. The Paraopeba River was mainly impacted by metal contamination resulting from the dam collapse, whereas nutrient contamination, mainly from urban and industrial discharges, predominantly affected its tributaries. Additionally, the elevated concentrations of aluminum, iron, nitrate, and sulfate in both main river and tributaries can be attributed to diffuse and point source pollution. In terms of hydromorphology and soil type, the interaction between woody vegetation and erosion-resistant soils, especially latosols, contributes to the stability of riverbanks in the main river. Meanwhile, in the tributaries, the presence of neosols and sparse vegetation in urbanized areas promoted riverbank erosion potentially amplifying pollution. While the study was conducted in a particular watershed, the findings are based on a methodology that can be applied universally. Hence, the insights on surface water quality from this research can be a valuable resource for researchers studying watersheds with diverse pollution sources.
    MeSH term(s) Rivers ; Environmental Monitoring/methods ; Water Pollutants, Chemical/analysis ; Water Pollution/analysis ; Water Quality ; Soil
    Chemical Substances Water Pollutants, Chemical ; Soil
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2024.123661
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2599: Show issues Location:
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  4. Article ; Online: COVID-19 and the Invisible Damage

    Renato Bessa de Melo / Nuno Teixeira Tavares / Raquel Duarte

    Acta Médica Portuguesa, Vol 33, Iss 5, Pp 293-

    2020  Volume 294

    Abstract: N/a. ...

    Abstract N/a.
    Keywords coronavírus ; prestação de cuidados de saúde ; surtos de doença ; Medicine ; R ; Medicine (General) ; R5-920 ; covid19
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher Ordem dos Médicos
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article: Late Recurrence of Pancreatic Solid Pseudopapillary Neoplasm With Peritoneal Carcinomatosis Treated With Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): A Case Report.

    Nogueiro, Jorge / Gomes, Fábio / Pacheco, João / Santos-Sousa, Hugo / Meireles, Sara / Bessa Melo, Renato / Aral, Marisa / Barbosa, Elisabete

    Cureus

    2022  Volume 14, Issue 11, Page(s) e31189

    Abstract: Pancreatic solid pseudopapillary neoplasm (SPN) is a rare malignant tumour predominantly affecting young women. The occurrence of peritoneal carcinomatosis (PC) in this setting is an even rarer condition, usually related to perioperative tumour rupture. ... ...

    Abstract Pancreatic solid pseudopapillary neoplasm (SPN) is a rare malignant tumour predominantly affecting young women. The occurrence of peritoneal carcinomatosis (PC) in this setting is an even rarer condition, usually related to perioperative tumour rupture. We present a case of a 43-year-old woman who previously underwent distal splenopancreatectomy after the diagnosis of a pancreatic SPN. Thirteen years later, the patient underwent a radical hysterectomy due to a uterine myoma. Intraoperatively, a peritoneal mass was additionally found and resected. Histological examination revealed an implant with morphology compatible with pancreatic SPN. The patient was then referred to our institution. Staging MRI and CT revealed multiple nodular lesions adjacent to the left colon, suggestive of peritoneal implants. The patient was then submitted to cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) with oxaliplatin and irinotecan. Histological examination confirmed peritoneal involvement by a pancreatic SPN. The postoperative course was unremarkable. Two years after surgery, the patient remains asymptomatic with no evidence of relapse. Despite SPN being cancer with a relatively indolent evolution, one needs to be aware of a possible recurrence several years after the primary resection, mainly in patients with evidence of intraoperative tumour rupture.
    Language English
    Publishing date 2022-11-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.31189
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  7. Article: Impacts of Sociodemographic Factors, Screening, and Organization of Health Services on Breast Cancer Mortality in Brazil: An Ecological Study of 20 Years.

    da Luz Costa, Thalita / Dantas, Diego Bessa / de Campos Gomes, Fabiana / Soares, Cleuma Oliveira / Castelhano, Janielly Reis / Fonseca, Laryssa Corrêa / Neves, Laura Maria Tomazi / Figueiredo, Eric Renato Lima / de Melo Neto, João Simão

    International journal of breast cancer

    2023  Volume 2023, Page(s) 6665725

    Abstract: Background: Breast cancer mortality is increasing in Brazil. This study examines the impact of sociodemographic factors, screening procedures, and primary healthcare (PHC) on breast cancer mortality.: Methods: An ecological study analyzed secondary ... ...

    Abstract Background: Breast cancer mortality is increasing in Brazil. This study examines the impact of sociodemographic factors, screening procedures, and primary healthcare (PHC) on breast cancer mortality.
    Methods: An ecological study analyzed secondary data of women diagnosed with breast cancer who died between 2000 and 2019. Sociodemographic factors, screening procedures, and PHC were examined in relation to breast cancer mortality. Statistical analyses included normality tests, Kruskal-Wallis and one-way ANOVA tests with post hoc comparisons, Pearson and Spearman correlation tests, age-period-cohort analysis, Kaplan-Meier analysis, and Cox regression analysis. Significance was set at
    Results: Mortality rates were higher in the southeast (15.77) and south (15.97) regions compared to the north (5.07) (
    Conclusions: Sociodemographic factors, screening procedures, and PHC are specific predictors of breast cancer mortality in Brazil.
    Language English
    Publishing date 2023-10-30
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2603566-2
    ISSN 2090-3189 ; 2090-3170
    ISSN (online) 2090-3189
    ISSN 2090-3170
    DOI 10.1155/2023/6665725
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  8. Article ; Online: Radiation-induced liver disease secondary to adjuvant therapy for extra-hepatic cholangiocarcinoma.

    Peixoto, Armando / Pereira, Pedro / Bessa de Melo, Renato / Macedo, Guilherme

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2016  Volume 49, Issue 2, Page(s) 227

    MeSH term(s) Aged ; Anastomosis, Roux-en-Y ; Bile Duct Neoplasms/pathology ; Bile Duct Neoplasms/therapy ; Bile Ducts, Intrahepatic/pathology ; Cholangiocarcinoma/pathology ; Cholangiocarcinoma/therapy ; Drug Therapy/methods ; Humans ; Liver/radiation effects ; Liver Diseases/diagnostic imaging ; Liver Diseases/etiology ; Male ; Radiation Injuries/pathology ; Radiotherapy/adverse effects ; Tomography, X-Ray Computed
    Language English
    Publishing date 2016-12-21
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2016.12.018
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1134: Show issues Location:
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  9. Article ; Online: The open abdomen: analysis of risk factors for mortality and delayed fascial closure in 101 patients.

    Morais, Marina / Gonçalves, Diana / Bessa-Melo, Renato / Devesa, Vítor / Costa-Maia, José

    Porto biomedical journal

    2018  Volume 3, Issue 2, Page(s) e14

    Abstract: Introduction: The core concepts of damage control and open abdomen in trauma surgery have been expanding for emergent general surgery. Temporary closures allow ease of access to the abdominal cavity for source control.The aim of the current study was to ...

    Abstract Introduction: The core concepts of damage control and open abdomen in trauma surgery have been expanding for emergent general surgery. Temporary closures allow ease of access to the abdominal cavity for source control.The aim of the current study was to assess the outcomes of patients who underwent open abdomen management for acute abdominal conditions and evaluate risk factors for worse outcomes and inability of fascial closure during the initial hospitalization.
    Methods: We conducted a retrospective analysis of 101 patients submitted to laparostomy in a single institution from January 2009 to March 2017. The evaluated outcomes were mortality, local morbidity, and rate of primary fascial closure.
    Results: The most common indications for open abdomen were bowel perforation, bowel ischemia, and necrotizing pancreatitis. Global in-hospital mortality rate was 62.4%. For the 37 patients discharged from the hospital, a definitive abdominal closure was attained in 28.Multivariable logistic regression analysis revealed that people older than 60 years of age and with Acute Physiology and Chronic Health Evaluation (APACHE II) scores over 18.5 had higher in-hospital mortality rates. Definitive fascial closure was statistically associated with a lower number of re-interventions and ICU stay.
    Conclusions: Open abdomen management may be appropriate in these critically ill patients; however, it continues to be associated with significantly high mortality, especially in elder patients and with higher APACHE II scores. Recognition of risk factors for fascia closure failure should promote the investigation for a tailored surgical approach in these patients.
    Language English
    Publishing date 2018-07-03
    Publishing country United States
    Document type Journal Article
    ISSN 2444-8672
    ISSN (online) 2444-8672
    DOI 10.1016/j.pbj.0000000000000014
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  10. Article ; Online: Genomic Surveillance of SARS-CoV-2 in Healthcare Workers: A Critical Sentinel Group for Monitoring the SARS-CoV-2 Variant Shift.

    Padilha, Dayane Azevedo / Souza, Doris Sobral Marques / Kawagoe, Eric Kazuo / Filho, Vilmar Benetti / Amorim, Ariane Nicaretta / Barazzetti, Fernando Hartmann / Schörner, Marcos André / Fernandes, Sandra Bianchini / Coelho, Bruna Kellet / Rovaris, Darcita Buerger / Dos Anjos, Marlei Pickler Debiase / Moser, Juliana Righetto / Melo, Fernanda Rosene / De Souza, Bianca Bittencourt / Bessa, Dimitri da Costa / Mendes, Fernando Henrique de Paula E Silva / Boing, Alexandra Crispim / Boing, Antonio Fernando / Lacerda, Josimari Telino de /
    Moura, Guilherme Valle / Bastiani, Daniela Carolina De / Moraes, Milene Höehr de / De Oliveira, Luiz Felipe Valter / Moreira, Renato Simões / Stoco, Patricia Hermes / Bazzo, Maria Luiza / Fongaro, Gislaine / Wagner, Glauber

    Viruses

    2023  Volume 15, Issue 4

    Abstract: SARS-CoV-2 genome surveillance is important for monitoring risk groups and health workers as well as data on new cases and mortality rate due to COVID-19. We characterized the circulation of SARS-CoV-2 variants from May 2021 to April 2022 in the state of ...

    Abstract SARS-CoV-2 genome surveillance is important for monitoring risk groups and health workers as well as data on new cases and mortality rate due to COVID-19. We characterized the circulation of SARS-CoV-2 variants from May 2021 to April 2022 in the state of Santa Catarina, southern Brazil, and evaluated the similarity between variants present in the population and healthcare workers (HCW). A total of 5291 sequenced genomes demonstrated the circulation of 55 strains and four variants of concern (Alpha, Delta, Gamma and Omicron-sublineages BA.1 and BA.2). The number of cases was relatively low in May 2021, but the number of deaths was higher with the Gamma variant. There was a significant increase in both numbers between December 2021 and February 2022, peaking in mid-January 2022, when the Omicron variant dominated. After May 2021, two distinct variant groups (Delta and Omicron) were observed, equally distributed among the five Santa Catarina mesoregions. Moreover, from November 2021 to February 2022, similar variant profiles between HCW and the general population were observed, and a quicker shift from Delta to Omicron in HCW than in the general population. This demonstrates the importance of HCW as a sentinel group for monitoring disease trends in the general population.
    MeSH term(s) Humans ; SARS-CoV-2/genetics ; COVID-19/epidemiology ; Genomics ; Health Personnel
    Language English
    Publishing date 2023-04-17
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15040984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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