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  1. Article: [COVID-19: TOPICAL ISSUES OF CLINIC ACTIVITIES DURING A PANDEMIC].

    Fartushok, T

    Georgian medical news

    2020  , Issue 306, Page(s) 122–132

    Abstract: World Health Organization has declared coronavirus disease (COVID-19, SARS-CoV-2) a pandemic. There is little evidence regarding the negative impact of COVID-19 infection on women's reproductive health. Previous coronavirus outbreaks that occurred in ... ...

    Abstract World Health Organization has declared coronavirus disease (COVID-19, SARS-CoV-2) a pandemic. There is little evidence regarding the negative impact of COVID-19 infection on women's reproductive health. Previous coronavirus outbreaks that occurred in previous years are known to include severe acute respiratory syndrome (SARS) in 2002-2003 and Middle East respiratory syndrome (MERS), which was first reported in 2012. So far, there is no evidence that pregnant women are more susceptible to COVID-19 than the general population. This short review provides a review of the scientific literature, which highlights the classification of respiratory viruses, transmission routes, transmission factors, virus-related diseases, case determination of COVID-19, clinical symptoms of COVID-19, laboratory diagnostics of COVID-19, algorithm the doctor's actions to examine patients, the impact on pregnancy, the treatment of pregnant women, women in childbirth and puerperas, as well as tactics of managing newborns in a pandemic, measures to prevent spread in a medical institution are highlighted.
    MeSH term(s) Ambulatory Care Facilities ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/therapy ; Coronavirus Infections/transmission ; Female ; Humans ; Infant, Newborn ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/therapy ; Pneumonia, Viral/transmission ; Pregnancy ; Pregnancy Complications, Infectious/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language Russian
    Publishing date 2020-10-16
    Publishing country Georgia (Republic)
    Document type Journal Article ; Review
    ZDB-ID 2443648-3
    ISSN 1512-0112
    ISSN 1512-0112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: DIABETES MELLITUS AND COVID-19: TODAY'S CHALLENGES.

    Markin, L / Fartushok, T / Fartushok, N / Soyka, L / Fedevych, Yu

    Georgian medical news

    2023  , Issue 337, Page(s) 43–50

    Abstract: Рatients with diabetes have more complications and higher mortality from COVID-19. This is due to the fact that diabetes impairs the immune response. Hyperglycemia causes a violation of the immune response, which in turn cannot control the spread of ... ...

    Abstract Рatients with diabetes have more complications and higher mortality from COVID-19. This is due to the fact that diabetes impairs the immune response. Hyperglycemia causes a violation of the immune response, which in turn cannot control the spread of pathogenic microorganisms and therefore patients with diabetes are more susceptible to infections. The purpose of the work ₋₋ analysis of bibliometric databases of literature on new developments in diabetes and COVID-19 and focused on clinical recommendations for patients with diabetes infected with COVID-19. The search methods included a literature review of scientific articles that studied diabetes and COVID-19. According to the results of the analysis of the articles obtained as a result of the search in the PubMed, SCOPUS, Web of Science, MedScape databases, a combination of the terms "diabetes and SARS-CoV-2", "diabetes and COVID-19", "pathogenesis of diabetes in case of COVID-19", "pancreas", "clinical features", "diagnosis", "treatment", "clinical recommendations", we found 32 messages from 2020 to 2022. The main parameters of the study were outpatients and inpatients with diabetes and COVID-19 of middle and elderly age starting from 46 years and up to 82 years of age in France, China, the USA, Great Britain, in which a nationwide, retrospective, population-based study was conducted. The following concomitant diseases are included in the main studies: arterial hypertension, cardiovascular diseases, heart failure, chronic kidney disease, chronic obstructive pulmonary disease, myocardial infarction, cerebrovascular diseases. Issues of pathogenetic mechanisms in DM and COVID-19, as well as management of patients with DM and COVID-19 are highlighted.
    MeSH term(s) Aged ; Humans ; Middle Aged ; COVID-19 ; Diabetes Mellitus/epidemiology ; Hypertension ; Retrospective Studies ; SARS-CoV-2 ; Aged, 80 and over
    Language English
    Publishing date 2023-06-23
    Publishing country Georgia (Republic)
    Document type Review ; Journal Article
    ZDB-ID 2443648-3
    ISSN 1512-0112
    ISSN 1512-0112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [covid-19: Topical Issues of Clinic Activities during a Pandemic]

    Fartushok, T.

    Georgian Med News

    Abstract: World Health Organization has declared coronavirus disease (COVID-19, SARS-CoV-2) a pandemic There is little evidence regarding the negative impact of COVID-19 infection on women's reproductive health Previous coronavirus outbreaks that occurred in ... ...

    Abstract World Health Organization has declared coronavirus disease (COVID-19, SARS-CoV-2) a pandemic There is little evidence regarding the negative impact of COVID-19 infection on women's reproductive health Previous coronavirus outbreaks that occurred in previous years are known to include severe acute respiratory syndrome (SARS) in 2002-2003 and Middle East respiratory syndrome (MERS), which was first reported in 2012 So far, there is no evidence that pregnant women are more susceptible to COVID-19 than the general population This short review provides a review of the scientific literature, which highlights the classification of respiratory viruses, transmission routes, transmission factors, virus-related diseases, case determination of COVID-19, clinical symptoms of COVID-19, laboratory diagnostics of COVID-19, algorithm the doctor's actions to examine patients, the impact on pregnancy, the treatment of pregnant women, women in childbirth and puerperas, as well as tactics of managing newborns in a pandemic, measures to prevent spread in a medical institution are highlighted
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #896309
    Database COVID19

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  4. Article: MANAGEMENT OF PREGNANT WOMEN WITH COVID-19 - OWN EXPERIENCE.

    Markin, L / Fartushok, T / Mrochko, Yu / Pidhirnyj, Ya

    Georgian medical news

    2022  , Issue 323, Page(s) 38–47

    Abstract: The purpose of the study is to analyze the results of managing pregnant women and newborns with COVID-19. Under observation were 208 pregnant women who were admitted to the municipal non-profit enterprise "Maternity Hospital №1 in Lviv». The department ... ...

    Abstract The purpose of the study is to analyze the results of managing pregnant women and newborns with COVID-19. Under observation were 208 pregnant women who were admitted to the municipal non-profit enterprise "Maternity Hospital №1 in Lviv». The department of extragenital pathology was specially equipped for patients. Based on clinical examination, epidemiological history and laboratory tests, a diagnosis of COVID-19 was made. COVID-19 was diagnosed in 179 (86.1%) pregnant women. 29 (16.2%) women were admitted to the intensive care unit and 1 (0.6%) woman required non-invasive mechanical ventilation. 74 women gave birth, of which 35 (47.3%) women - by caesarean section, the rest of the pregnant women after COVID-19 treatment were discharged under the supervision of a antenatal clinic doctor with the progression of pregnancy. The most common indication for caesarean section was fetal distress - 19 (54.2%) women. In 14 (18.9%) cases, the delivery was premature. The epidemic of severe acute respiratory syndrome (SARS - severe acute respiratory syndrome) caused by SARS-CoV showed that coronaviruses can cause not only mild and moderate respiratory diseases, but also severe, and even fatal, primary viral pneumonias, mortality from which, according to the WHO, worldwide was 17.6%. The risk of severe illness in pregnant women with SARS-CoV-2 does not increase compared with the general population, according to our observations was 15.1%, which corresponds to the data of international experts. There is currently no evidence of miscarriage, fetal malformations, spontaneous preterm birth, and vertical transmission of the virus. Thromboprophylaxis is carried out for hospitalized women who have had a symptomatic course of COVID-19. In the treatment, cephalosporins II-III generation and macrolides are used. Corticosteroids are used to treat COVID-19 in women requiring oxygen support.
    MeSH term(s) Abortion, Spontaneous ; Anticoagulants ; COVID-19/drug therapy ; Cesarean Section ; Female ; Humans ; Infant, Newborn ; Pregnancy ; Pregnancy Complications, Infectious/drug therapy ; Pregnancy Complications, Infectious/epidemiology ; Pregnant Women ; Premature Birth/epidemiology ; SARS-CoV-2 ; Venous Thromboembolism
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-03-10
    Publishing country Georgia (Republic)
    Document type Journal Article
    ZDB-ID 2443648-3
    ISSN 1512-0112
    ISSN 1512-0112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Disorders in lipid composition and properties of plasma membrane in epithelial cells of the placental villous chorion in chlamydial infection].

    Iablons'ka, S V / Fartushok, T V / Vesel's'kyĭ, S P / Kondratiuk, O A / Besedin, V M / Rybal'chenko, V K

    Ukrains'kyi biokhimichnyi zhurnal (1999 )

    2008  Volume 80, Issue 2, Page(s) 135–140

    Abstract: Lipid composition of plasma membranes of placental epithelial cells of villous chorion of healthy women and those with chlamydiosis has been studied. Lipid composition of plasma membranes of ill women differs from that of healthy women by reduction of ... ...

    Abstract Lipid composition of plasma membranes of placental epithelial cells of villous chorion of healthy women and those with chlamydiosis has been studied. Lipid composition of plasma membranes of ill women differs from that of healthy women by reduction of total phospholipids quantity, by the increase of the level of free cholesterol and free fatty acids. A disturbance in the ratio between certain lipid fractions and increasing quantity of lysophospholipids is observed. Two-fold oppression of plasma membranes Na+, K+ -ATPase activity of placental epithelial cells of villous chorion in ill women has been detected but Mg2+, Ca2+ -ATPase activity has not changed. Thus chlamydial infection causes significant disorders in lipid composition and functioning of epithelial cells membranes of chorion.
    MeSH term(s) Ca(2+) Mg(2+)-ATPase/metabolism ; Cell Membrane/enzymology ; Cell Membrane/metabolism ; Chlamydia Infections/metabolism ; Chorionic Villi/metabolism ; Epithelial Cells/enzymology ; Epithelial Cells/metabolism ; Female ; Humans ; Membrane Lipids/metabolism ; Phospholipids/metabolism ; Pregnancy ; Pregnancy Complications, Infectious/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism
    Chemical Substances Membrane Lipids ; Phospholipids ; Ca(2+) Mg(2+)-ATPase (EC 3.6.1.-) ; Sodium-Potassium-Exchanging ATPase (EC 3.6.3.9)
    Language Ukrainian
    Publishing date 2008-03
    Publishing country Ukraine
    Document type English Abstract ; Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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