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  1. Article ; Online: H

    Xu, Jun / Zhong, Yali / Wang, Weixin / Gao, Rui / Wang, Yini / Tong, Fei / Sun, Jiahui / Hong, Miaofang / Qiao, Lingyan / Qiao, Weiwei / Mei, Qibing / Wu, Jianming

    Nanoscale

    2024  Volume 16, Issue 3, Page(s) 1282–1290

    Abstract: As emerging nanosystems, nanomotors have been applied in the active treatment of many diseases. In this paper, Pt@chitosan-loaded melatonin asymmetrical nanomaterials embedded with L-serine (S, kidney injury molecule 1-targeting agent) were constructed ... ...

    Abstract As emerging nanosystems, nanomotors have been applied in the active treatment of many diseases. In this paper, Pt@chitosan-loaded melatonin asymmetrical nanomaterials embedded with L-serine (S, kidney injury molecule 1-targeting agent) were constructed to alleviate acute kidney injury (AKI). The Janus nanocarriers arrived at the renal injury site
    MeSH term(s) Humans ; Hydrogen Peroxide ; Melatonin ; Nanostructures ; Permeability ; Acute Kidney Injury/drug therapy
    Chemical Substances Hydrogen Peroxide (BBX060AN9V) ; Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d3nr04808j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: H

    Cai, Wanqian / Zhang, Chongbiao / Wu, Yourong / Wang, Wei / Lin, Mei / Lin, Tengfei / Lin, Cong / Gao, Min / Zhao, Chunlin / Wu, Xiao

    RSC advances

    2023  Volume 13, Issue 17, Page(s) 11720–11727

    Abstract: As emerging contaminants, antineoplastic drugs are widely used, but their residues in water may cause long-term genotoxicity to aquatic organisms and human beings. Here, waste moxa ash was selected as biomass raw material and modified by ball milling to ... ...

    Abstract As emerging contaminants, antineoplastic drugs are widely used, but their residues in water may cause long-term genotoxicity to aquatic organisms and human beings. Here, waste moxa ash was selected as biomass raw material and modified by ball milling to obtain carbon-based materials with excellent adsorption performance, which were used to remove the antineoplastic drug mitoxantrone (MTX) from water. The experimental results indicate that moxa ash modified by ball milling in hydrogen peroxide exhibits ultrafast removal of MTX (the removal efficiency reaches 97.66% in 1 min and 99.72% in 30 min). The pseudo-second-order kinetics and Freundlich isotherm models accurately describe the MTX adsorption process, and the mechanism of adsorption probably involves pore filling, hydrogen bond, π-π interaction and electrostatic attraction. Not only that, moxa ash also has the ability to remove dyes such as malachite green (97.81%) and methylene blue (99.97%). In this study, a simple and environmentally friendly process was used to convert waste moxa ash into an effective MTX adsorbent, providing a feasible solution for controlling MTX pollution and identifying a circular and economic way to reuse the waste.
    Language English
    Publishing date 2023-04-14
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra00988b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: H

    Liu, Xiang-Mei / Wang, Yu-Ling / Ren, Shu-Wei / Cao, Jun-Tao / Liu, Yan-Ming

    The Analyst

    2022  Volume 147, Issue 11, Page(s) 2508–2514

    Abstract: ... ratiometric sensor based on the bidirectional regulation of two independent co-reaction systems by H ...

    Abstract Potential-resolved electrochemiluminescence (ECL) ratiometric analysis has become a research hotspot in bioassays by virtue of its good accuracy, versatility and specificity. Current ECL ratiometry mainly focuses on the competition for the co-reactant or quantitative analysis using a variable signal and a changeless signal; the disorganized change or small difference between the two signals may affect the accuracy and sensitivity of detection. In this study, we have developed a novel ECL ratiometric sensor based on the bidirectional regulation of two independent co-reaction systems by H
    MeSH term(s) Biosensing Techniques ; Electrochemical Techniques ; Electrodes ; Humans ; Hydrogen Peroxide ; Limit of Detection ; Luminescent Measurements
    Chemical Substances Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2022-05-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d2an00601d
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2423: Show issues Location:
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  4. Article ; Online: H

    Chen, Jianqiang / Jin, Xiangxiang / Shen, Zhe / Mei, Yanan / Zhu, Jufan / Zhang, Xiaodan / Liang, Guang / Zheng, Xiaohui

    Medical oncology (Northwood, London, England)

    2021  Volume 38, Issue 6, Page(s) 59

    Abstract: ... we investigated the anticancer activity of TMPyP4 in A549 and PANC cells cultured in H ...

    Abstract Cancer is one of the diseases that threatens human health and is a leading cause of mortality worldwide. High levels of reactive oxygen species (ROS) have been observed in cancer tissues compared with normal tissues in vivo, and it is not yet known how this influences chemotherapeutic drug action. Cationic porphyrin 5,10,15,20-tetra-(N-methyl-4-pyridyl) porphyrin (TMPyP4) is a photosensitizer used in photodynamic therapy (PDT) and a telomerase inhibitor used in the treatment of telomerase-positive cancer. Here, we investigated the anticancer activity of TMPyP4 in A549 and PANC cells cultured in H
    MeSH term(s) A549 Cells ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Cell Line, Tumor ; Comet Assay ; DNA Damage ; Hepatocytes/drug effects ; Humans ; Hydrogen Peroxide/administration & dosage ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/drug effects ; Mitochondria/genetics ; Mitochondria/metabolism ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; Porphyrins/administration & dosage ; Reactive Oxygen Species/metabolism ; Tumor Microenvironment/drug effects
    Chemical Substances Porphyrins ; Reactive Oxygen Species ; tetra(4-N-methylpyridyl)porphine (38673-65-3) ; Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2021-04-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1201189-7
    ISSN 1559-131X ; 0736-0118 ; 1357-0560
    ISSN (online) 1559-131X
    ISSN 0736-0118 ; 1357-0560
    DOI 10.1007/s12032-021-01505-x
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1899: Show issues Location:
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  5. Article: H

    Mei, Qiong / Yang, Yong / Ye, Shenhai / Liang, Weifang / Wang, Xuming / Zhou, Jie / Yu, Chulang / Yan, Chengqi / Chen, Jianping

    Plants (Basel, Switzerland)

    2019  Volume 8, Issue 9

    Abstract: Oryza meyeriana is a wild species of rice with high resistance to Xanthomonas oryzae pv. oryzae (Xoo), but the detailed resistance mechanism is unclear. Ribulose-1, 5-bisphosphate carboxylase/oxygenase (Rubisco) activase (RCA) is an important enzyme that ...

    Abstract Oryza meyeriana is a wild species of rice with high resistance to Xanthomonas oryzae pv. oryzae (Xoo), but the detailed resistance mechanism is unclear. Ribulose-1, 5-bisphosphate carboxylase/oxygenase (Rubisco) activase (RCA) is an important enzyme that regulates photosynthesis by activating Rubisco. We have previously reported that
    Language English
    Publishing date 2019-09-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants8090351
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  6. Article ; Online: H

    Chen, Mei-Kuang / Du, Yi / Sun, Linlin / Hsu, Jennifer L / Wang, Yu-Han / Gao, Yuan / Huang, Jiaxing / Hung, Mien-Chie

    The Journal of biological chemistry

    2019  Volume 294, Issue 21, Page(s) 8516–8528

    Abstract: ... anticancer agents, such as ionizing irradiation and chemotherapy drugs. The ROS H ...

    Abstract Reactive oxygen species (ROS) are cellular by-products produced from metabolism and also anticancer agents, such as ionizing irradiation and chemotherapy drugs. The ROS H
    MeSH term(s) Active Transport, Cell Nucleus/drug effects ; Breast Neoplasms/enzymology ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Membrane/enzymology ; Cell Membrane/genetics ; Cell Membrane/pathology ; Cell Nucleus/enzymology ; Cell Nucleus/genetics ; Cell Nucleus/pathology ; Coatomer Protein/genetics ; Coatomer Protein/metabolism ; DNA Damage ; DNA Repair ; Female ; Humans ; Hydrogen Peroxide/pharmacology ; Proto-Oncogene Proteins c-met/genetics ; Proto-Oncogene Proteins c-met/metabolism ; SEC Translocation Channels/genetics ; SEC Translocation Channels/metabolism ; Signal Transduction/drug effects
    Chemical Substances COPG1 protein, human ; Coatomer Protein ; SEC Translocation Channels ; SEC61B protein, human ; Hydrogen Peroxide (BBX060AN9V) ; MET protein, human (EC 2.7.10.1) ; Proto-Oncogene Proteins c-met (EC 2.7.10.1)
    Language English
    Publishing date 2019-04-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1074/jbc.RA118.005953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.108: Show issues Location:
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  7. Article ; Online: H

    Meng, Xiang-Min / Huang, Xu / Lu, Hong-Li / Zhang, Chun-Mei / Kim, Young-Chul / Chen, Jie / Xu, Wen-Xie

    Experimental physiology

    2017  Volume 102, Issue 7, Page(s) 779–790

    Abstract: ... the relationship between H ...

    Abstract New findings: What is the central question of this study? The present study investigated the relationship between H
    Language English
    Publishing date 2017-07-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1016295-1
    ISSN 1469-445X ; 0958-0670
    ISSN (online) 1469-445X
    ISSN 0958-0670
    DOI 10.1113/EP086288
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    Uc I Zs.102: Show issues Location:
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  8. Article ; Online: H

    Liang, Xin / Chen, Yu-Lin / Jiang, Xiao-Jing / Wang, Sheng-Mei / Zhang, Ji-Wen / Gui, Shuang-Ying

    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

    2017  Volume 100, Page(s) 155–162

    Abstract: The main objective of this study was to develop reversed hexagonal (H ...

    Abstract The main objective of this study was to develop reversed hexagonal (H
    MeSH term(s) Administration, Cutaneous ; Analgesics/administration & dosage ; Analgesics/blood ; Analgesics/pharmacokinetics ; Analgesics/therapeutic use ; Animals ; Anti-Inflammatory Agents/administration & dosage ; Anti-Inflammatory Agents/blood ; Anti-Inflammatory Agents/pharmacokinetics ; Anti-Inflammatory Agents/therapeutic use ; Biological Availability ; Drug Delivery Systems ; Edema/drug therapy ; Fatty Alcohols/chemistry ; Female ; Liquid Crystals/chemistry ; Male ; Mice ; Pain/drug therapy ; Rats, Wistar ; Salicylates/administration & dosage ; Salicylates/blood ; Salicylates/pharmacokinetics ; Salicylates/therapeutic use ; Skin/drug effects ; Skin/metabolism ; Skin Absorption ; Skin Irritancy Tests
    Chemical Substances Analgesics ; Anti-Inflammatory Agents ; Fatty Alcohols ; Salicylates ; 3,7,11,15-tetramethyl-1,2,3-hexadecanetriol (8LVI07A72W) ; methyl salicylate (LAV5U5022Y)
    Language English
    Publishing date 2017-03-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1154366-8
    ISSN 1879-0720 ; 0928-0987
    ISSN (online) 1879-0720
    ISSN 0928-0987
    DOI 10.1016/j.ejps.2016.12.033
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    Zs.A 3705: Show issues Location:
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  9. Article ; Online: Methane-H

    Wang, Yong / Zhao, Wenru / Chen, Xiaofeng / Ji, Yinjie / Zhu, Xilei / Chen, Xiaomai / Mei, Donghai / Shi, Hui / Lercher, Johannes A

    Journal of the American Chemical Society

    2024  Volume 146, Issue 12, Page(s) 8630–8640

    Abstract: H ...

    Abstract H
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.4c00738
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    In stock of ZB MED Bonn / Germany

    Z 4' 55/32: Show issues
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  10. Article ; Online: Rh proteins and H

    Zhao, Xue Fei / Huang, Jing / Li, Wen / Wang, Shuang Yi / Liang, Li Qun / Zhang, Li Min / Liew, Hon Jung / Chang, Yu Mei

    Ecotoxicology and environmental safety

    2024  Volume 273, Page(s) 116160

    Abstract: High alkaline environment can lead to respiratory alkalosis and ammonia toxification to freshwater fish. However, the Amur ide (Leuciscus waleckii), which inhabits an extremely alkaline lake in China with titratable alkalinity up to 53.57 mM (pH 9.6) has ...

    Abstract High alkaline environment can lead to respiratory alkalosis and ammonia toxification to freshwater fish. However, the Amur ide (Leuciscus waleckii), which inhabits an extremely alkaline lake in China with titratable alkalinity up to 53.57 mM (pH 9.6) has developed special physiological and molecular mechanisms to adapt to such an environment. Nevertheless, how the Amur ide can maintain acid-base balance and perform ammonia detoxification effectively remains unclear. Therefore, this study was designed to study the ammonia excretion rate (T
    MeSH term(s) Animals ; Ammonia/toxicity ; Ammonia/metabolism ; Lakes ; Cypriniformes ; Membrane Transport Proteins/metabolism ; Alkalies ; Gills/metabolism
    Chemical Substances Ammonia (7664-41-7) ; Membrane Transport Proteins ; Alkalies
    Language English
    Publishing date 2024-03-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 436536-7
    ISSN 1090-2414 ; 0147-6513
    ISSN (online) 1090-2414
    ISSN 0147-6513
    DOI 10.1016/j.ecoenv.2024.116160
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