LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 9 of total 9

Search options

  1. Article ; Online: Tumor PD-L1 expression and molecular profiling are not associated with immune checkpoint inhibitor-induced thyroid dysfunction in advanced NSCLC patients.

    Horesh, Adi / Pollack, Rena / Nechushtan, Hovav / Dresner-Pollak, Rivka / Neuman, Tzahi

    Pathology oncology research : POR

    2023  Volume 29, Page(s) 1610951

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Immune Checkpoint Inhibitors/adverse effects ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Thyroid Gland/pathology ; B7-H1 Antigen ; Retrospective Studies ; Antineoplastic Agents, Immunological/adverse effects ; Programmed Cell Death 1 Receptor
    Chemical Substances Immune Checkpoint Inhibitors ; B7-H1 Antigen ; Antineoplastic Agents, Immunological ; Programmed Cell Death 1 Receptor
    Language English
    Publishing date 2023-04-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1375979-6
    ISSN 1532-2807 ; 1219-4956
    ISSN (online) 1532-2807
    ISSN 1219-4956
    DOI 10.3389/pore.2023.1610951
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Risk of colorectal advanced neoplasia in patients with acute diverticulitis with and without previous colonoscopy.

    Albshesh, Ahmad / Ukashi, Offir / Lahat, Adi / Kopylov, Uri / Horesh, Nir / Pflantzer, Barak / Laish, Ido

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2023  Volume 25, Issue 5, Page(s) 897–904

    Abstract: Background and aim: Guidelines recommend a colonoscopy after an episode of complicated diverticulitis and after a first episode of uncomplicated diverticulitis. The influence of a previous colonoscopy on postdiverticulitis colonoscopic findings has not ... ...

    Abstract Background and aim: Guidelines recommend a colonoscopy after an episode of complicated diverticulitis and after a first episode of uncomplicated diverticulitis. The influence of a previous colonoscopy on postdiverticulitis colonoscopic findings has not been studied. The aim of this work was to examine the incidence of adenoma detection rate (ADR), advanced adenoma (AA) and colorectal cancer (CRC) in patients with diverticulitis with and without previous colonoscopy.
    Method: This was a retrospective case-control study of subjects with acute diverticulitis. Subsequent and previous colonoscopies were abstracted for ADR, AA and CRC diagnoses. The incidence of neoplasia was compared between patients with and without previous colonoscopy and also with that of a screening population.
    Results: Compared with a healthy control group (n = 975), diverticulitis patients without prior colonoscopy (n = 325) had a significantly higher ADR (26.8% vs. 20.5%, p = 0.019) and invasive CRC rate (0.9% vs. 0%, p = 0.016). Risk factors for advanced neoplasia included age ≥ 70 years and complicated diverticulitis. Among subjects with diverticulitis and previous colonoscopy (n = 124), only one patient developed AA and there were no cancer cases.
    Conclusions: A previous normal colonoscopy within 5 years before diverticulitis probably overshadows other risk factors for findings of advanced neoplasia and should be considered in the decision to repeat a colonoscopy.
    MeSH term(s) Humans ; Aged ; Retrospective Studies ; Case-Control Studies ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/etiology ; Colonoscopy ; Diverticulitis ; Adenoma/complications ; Adenoma/diagnosis ; Adenoma/epidemiology ; Early Detection of Cancer
    Language English
    Publishing date 2023-02-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16481
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: [Clinical and epidemiological characteristics of SARS-CoV-2].

    Horesh, Adi / Glassberg, Elon / Bader, Tarif / Twig, Gilad

    Harefuah

    2020  Volume 159, Issue 4, Page(s) 226–228

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language Hebrew
    Publishing date 2020-08-14
    Publishing country Israel
    Document type News
    ZDB-ID 953872-0
    ISSN 0017-7768
    ISSN 0017-7768
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Adolescent and Childhood Obesity and Excess Morbidity and Mortality in Young Adulthood-a Systematic Review.

    Horesh, Adi / Tsur, Avishai M / Bardugo, Aya / Twig, Gilad

    Current obesity reports

    2021  Volume 10, Issue 3, Page(s) 301–310

    Abstract: Purpose of review: Rates of childhood obesity have been soaring in recent decades. The association between obesity in adulthood and excess morbidity and mortality has been readily established, whereas the association of childhood and adolescent obesity ... ...

    Abstract Purpose of review: Rates of childhood obesity have been soaring in recent decades. The association between obesity in adulthood and excess morbidity and mortality has been readily established, whereas the association of childhood and adolescent obesity has not. The purpose of this review is to summarize existing data regarding the association of the presence of obesity in childhood/adolescence and early-onset adverse outcomes in adulthood, with specific focus on young adults under the age of 45 years.
    Recent findings: Diabetes, cancer, and cardiometabolic outcomes in midlife are closely linked to childhood and adolescent obesity. Childhood and adolescent obesity confer major risks of excess and premature morbidity and mortality, which may be evident before age 30 years in both sexes. The scientific literature is mixed regarding the independent risk of illness, which may be attributed to childhood BMI regardless of adult BMI, and additional data is required to establish causality between the two. Nonetheless, the increasing prevalence of childhood and adolescent obesity may impose an increase of disease burden in midlife, emphasizing the need for effective interventions to be implemented at a young age.
    MeSH term(s) Adolescent ; Adult ; Body Mass Index ; Child ; Diabetes Mellitus ; Female ; Humans ; Male ; Middle Aged ; Morbidity ; Pediatric Obesity/epidemiology ; Prevalence ; Risk Factors ; Young Adult
    Language English
    Publishing date 2021-05-05
    Publishing country United States
    Document type Journal Article ; Review ; Systematic Review
    ISSN 2162-4968
    ISSN (online) 2162-4968
    DOI 10.1007/s13679-021-00439-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: I feel you: Prepandemic physiological synchrony and emotional contagion during COVID-19.

    Mayo, Oded / Horesh, Danny / Korisky, Adi / Milstein, Nir / Zadok, Ester / Tomashin, Alon / Gordon, Ilanit

    Emotion (Washington, D.C.)

    2022  Volume 23, Issue 3, Page(s) 753–763

    Abstract: The COVID-19 pandemic has a major impact on mental well-being and interpersonal relationships. Nonetheless, little is known about the complex interactions between one's overall perceived interpersonal closeness and physiological or psychological aspects ... ...

    Abstract The COVID-19 pandemic has a major impact on mental well-being and interpersonal relationships. Nonetheless, little is known about the complex interactions between one's overall perceived interpersonal closeness and physiological or psychological aspects of interpersonal functioning. This study aimed to understand the interaction between perceived interpersonal closeness during COVID-19 and interpersonal mechanisms in predicting well-being. We focused on two interpersonal mechanisms, one physiological and the other psychological: (a) prepandemic physiological synchrony, a physiological measure of interpersonal coupling, and (b) peripandemic emotional contagion, one's tendency to "catch" others' emotions. One hundred fifty-five participants took part in the study. Cardiological interbeat interval synchrony was collected 1.5 to 3 years prior to the beginning of the COVID pandemic in two previous lab studies. Participants were recontacted during the pandemic, this time to complete several questionnaires tapping into perceived interpersonal closeness, tendency for emotional contagion, and psychological well-being during COVID. As hypothesized, overall perceived interpersonal closeness was positively related to well-being. Moreover, this effect was moderated by one's tendency for emotional contagion or by physiological synchrony. Thus, individuals with higher emotional contagion scores or higher physiological synchrony had higher well-being if their interpersonal closeness was perceived as greater. Conversely, their well-being was lower if they perceived their interpersonal closeness as weaker. These results emphasize that individuals may be differentially susceptible to the effects of their relationships on their well-being. Future mental health interventions should consider both the quality of one's perceived interpersonal closeness and the extent to which one is sensitive to others' emotional experiences. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
    MeSH term(s) Humans ; COVID-19 ; Pandemics ; Emotions/physiology ; Interpersonal Relations ; Surveys and Questionnaires
    Language English
    Publishing date 2022-08-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2102391-8
    ISSN 1931-1516 ; 1528-3542
    ISSN (online) 1931-1516
    ISSN 1528-3542
    DOI 10.1037/emo0001122
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Pre-pandemic autonomic nervous system activity predicts mood regulation expectancies during COVID-19 in Israel.

    Gordon, Ilanit / Horesh, Danny / Milstein, Nir / Tomashin, Alon / Mayo, Oded / Korisky, Adi

    Psychophysiology

    2021  Volume 58, Issue 11, Page(s) e13910

    Abstract: Despite the unfolding impact of the COVID-19 pandemic on psychological well-being, there is a lack of prospective studies that target physiological markers of distress. There is a need to examine physiological predictors from the pre-pandemic period to ... ...

    Abstract Despite the unfolding impact of the COVID-19 pandemic on psychological well-being, there is a lack of prospective studies that target physiological markers of distress. There is a need to examine physiological predictors from the pre-pandemic period to identify and treat individuals at-risk. In this study, our aim was to use pre-pandemic markers of autonomic nervous system (ANS) parasympathetic and sympathetic regulation to predict individuals' psychological well-being during the crisis. We also assessed the role of mood regulation expectancies as a mediator of the association between pre-pandemic physiological measures and COVID-related well-being. In May to June 2020, 185 Israeli adults completed online questionnaires assessing their mood regulation expectancies since COVID-19 began, and their current well-being. These individuals had participated in lab studies 1.5-3 years prior to this assessment, where their physiological measures were taken, including respiratory sinus arrhythmia (RSA) and skin conductance level (SCL). RSA was positively related to mood regulation expectancies during COVID-19 (b = 3.46, 95% CI [0.84, 6.05]). Mood regulation expectancies, in turn, positively predicted well-being during the crisis (b = 0.021, 95% CI [0.016, 0.027]). The mediation was significant and moderated by SCL (index = -0.09, 95% CI [-0.02, -0.0001]), such that it was strongest for individuals with low SCL. We point to pre-pandemic physiological mechanisms underlying individuals' mental well-being during the COVID-19 pandemic. These findings have theoretical, diagnostic, and clinical implications that may refine our understanding of the physiological basis of resilience to the COVID-19 pandemic and thus may be implemented to identify and assist individuals in these times.
    MeSH term(s) Adolescent ; Adult ; Affect ; Autonomic Nervous System/physiology ; Autonomic Nervous System/physiopathology ; COVID-19 ; Emotional Regulation ; Female ; Galvanic Skin Response ; Humans ; Israel ; Male ; Mental Health ; Motivation ; Respiratory Sinus Arrhythmia ; SARS-CoV-2 ; Young Adult
    Language English
    Publishing date 2021-07-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 209486-1
    ISSN 1540-5958 ; 0048-5772
    ISSN (online) 1540-5958
    ISSN 0048-5772
    DOI 10.1111/psyp.13910
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Agreement on Symptoms Between Children With Ulcerative Colitis and Their Caregivers: Towards Developing the TUMMY-UC.

    Marcovitch, Liron / Focht, Gili / Horesh, Anat / Shosberger, Adi / Hyams, Jeffrey / Bousvaros, Athos / Hale, Amy E / Baldassano, Robert / Otley, Anthony / Mack, David R / Kappelman, Michael D / Griffiths, Anne M / Turner, Dan

    Journal of pediatric gastroenterology and nutrition

    2021  Volume 73, Issue 2, Page(s) e35–e38

    Abstract: Abstract: As part of the development of the TUMMY-UC, a patient-reported outcome (PRO) measure for pediatric ulcerative colitis (UC), we aimed to explore agreement on UC symptoms between children and their caregivers. We conducted 44 interviews with ... ...

    Abstract Abstract: As part of the development of the TUMMY-UC, a patient-reported outcome (PRO) measure for pediatric ulcerative colitis (UC), we aimed to explore agreement on UC symptoms between children and their caregivers. We conducted 44 interviews with children ages 8-12 years, who completed the PRO version of the TUMMY-UC, and their caregivers, who completed the observer-reported outcome (obsRO) version. There was excellent agreement between the total TUMMY-UC PRO and obsRO scores (intra-class correlation coefficient = 0.92 [95% confidence interval 0.74-0.98]). The obsRO scores were always within the same disease-activity category as the corresponding PRO score (ie, remission, mild and moderate-severe disease). There was a strong correlation of the TUMMY-UC PRO and obsRO scores with physician global assessment of disease activity (r = 0.94 and r = 0.90, respectively, P < 0.001) and the pediatric UC activity index (r = 0.95 and r = 0.96; P < 0.001). These data support conceptual equivalence between the PRO and obsRO TUMMY-UC versions, and provide support for their incorporation into one score.
    MeSH term(s) Caregivers ; Child ; Colitis, Ulcerative/diagnosis ; Colitis, Ulcerative/therapy ; Humans ; Patient Reported Outcome Measures ; Physicians ; Severity of Illness Index
    Language English
    Publishing date 2021-01-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1097/MPG.0000000000003120
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Implicit death primes increase alcohol consumption.

    Ein-Dor, Tsachi / Hirschberger, Gilad / Perry, Adi / Levin, Noga / Cohen, Roi / Horesh, Hadar / Rothschild, Elad

    Health psychology : official journal of the Division of Health Psychology, American Psychological Association

    2014  Volume 33, Issue 7, Page(s) 748–751

    Abstract: Objective: The authors examined whether priming thoughts of death are associated with increases in alcohol consumption.: Method: Research assistants handed out fliers that were stacked in a random order to pedestrians walking through campus (N = 377). ...

    Abstract Objective: The authors examined whether priming thoughts of death are associated with increases in alcohol consumption.
    Method: Research assistants handed out fliers that were stacked in a random order to pedestrians walking through campus (N = 377). These fliers served to remind them of either their death or of an aversive condition unrelated to death (severe back pain), which served as the control. Then they were solicited to purchase an alcoholic or nonalcoholic beverage.
    Results: The authors used a 2 × 2 log-linear analysis, with type of prime (death-pain) and beverage type (alcoholic-nonalcoholic) as the independent variables and consumption (yes-no) as the outcome measure (11.9% of the total sample consumed a beverage). RESULTS revealed that a greater percentage of students who received the death prime consumed alcohol (36.59%) versus students in the pain prime condition (8.94%), G²(4, N = 377) = 64.8, p < .001, W = .41. The type of prime (death-pain) did not influence the consumption of nonalcoholic beverages.
    Conclusion: The current research indicates that death-related concerns may play a role in increasing the consumption of alcoholic beverages.
    MeSH term(s) Adult ; Alcohol Drinking/epidemiology ; Alcohol Drinking/psychology ; Alcoholic Beverages/statistics & numerical data ; Attitude to Death ; Beverages/statistics & numerical data ; Commerce/statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Students/psychology ; Students/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2014-07
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 226369-5
    ISSN 1930-7810 ; 0278-6133
    ISSN (online) 1930-7810
    ISSN 0278-6133
    DOI 10.1037/a0033880
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top