Article ; Online: K
Fundamental & clinical pharmacology
2023 Volume 37, Issue 6, Page(s) 1020–1049
Abstract: ... sensitive K: Results: KCOs prevent irreversible ischemia and reperfusion injury of the heart. K ... Conclusion: The cardioprotective effect of KCOs is mediated by the opening of mitochondrial K ...
Abstract | Background: The use of percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) is associated with a mortality rate of 5%-7%. It is clear that there is an urgent need to develop new drugs that can effectively prevent cardiac reperfusion injury. ATP-sensitive K Results: KCOs prevent irreversible ischemia and reperfusion injury of the heart. K Conclusion: The cardioprotective effect of KCOs is mediated by the opening of mitochondrial K |
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MeSH term(s) | Humans ; Animals ; No-Reflow Phenomenon ; Percutaneous Coronary Intervention ; Myocardial Reperfusion Injury/drug therapy ; Myocardial Reperfusion Injury/prevention & control ; Apoptosis ; Reperfusion ; Adenosine Triphosphate ; KATP Channels |
Chemical Substances | Adenosine Triphosphate (8L70Q75FXE) ; KATP Channels |
Language | English |
Publishing date | 2023-06-26 |
Publishing country | England |
Document type | Journal Article ; Review |
ZDB-ID | 639134-5 |
ISSN | 1472-8206 ; 0767-3981 |
ISSN (online) | 1472-8206 |
ISSN | 0767-3981 |
DOI | 10.1111/fcp.12924 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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