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  1. Book ; Online: Exploring Task-oriented Communication in Multi-agent System

    He, Guojun

    A Deep Reinforcement Learning Approach

    2022  

    Abstract: The multi-agent system (MAS) enables the sharing of capabilities among agents, such that collaborative tasks can be accomplished with high scalability and efficiency. MAS is increasingly widely applied in various fields. Meanwhile, the large-scale and ... ...

    Abstract The multi-agent system (MAS) enables the sharing of capabilities among agents, such that collaborative tasks can be accomplished with high scalability and efficiency. MAS is increasingly widely applied in various fields. Meanwhile, the large-scale and time-sensitive data transmission between agents brings challenges to the communication system. The traditional wireless communication ignores the content of the data and its impact on the task execution at the receiver, which makes it difficult to guarantee the timeliness and relevance of the information. This limitation leads to that traditional wireless communication struggles to effectively support emerging multi-agent collaborative applications. Faced with this dilemma, task-oriented communication is a potential solution, which aims to transmit task-relevant information to improve task execution performance. However, multi-agent collaboration itself is a complex class of sequential decision problems. It is challenging to explore efficient information flow in this context. In this article, we use deep reinforcement learning (DRL) to explore task-oriented communication in MAS. We begin with a discussion on the application of DRL to task-oriented communication. We then envision a task-oriented communication architecture for MAS, and discuss the designs based on DRL. Finally, we discuss open problems for future research and conclude this article.
    Keywords Computer Science - Multiagent Systems
    Subject code 004
    Publishing date 2022-08-22
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article: Detection of copy number variations based on a local distance using next-generation sequencing data.

    Liu, Guojun / Yang, Hongzhi / He, Zongzhen

    Frontiers in genetics

    2023  Volume 14, Page(s) 1147761

    Abstract: As one of the main types of structural variation in the human genome, copy number variation (CNV) plays an important role in the occurrence and development of human cancers. Next-generation sequencing (NGS) technology can provide base-level resolution, ... ...

    Abstract As one of the main types of structural variation in the human genome, copy number variation (CNV) plays an important role in the occurrence and development of human cancers. Next-generation sequencing (NGS) technology can provide base-level resolution, which provides favorable conditions for the accurate detection of CNVs. However, it is still a very challenging task to accurately detect CNVs from cancer samples with different purity and low sequencing coverage. Local distance-based CNV detection (LDCNV), an innovative computational approach to predict CNVs using NGS data, is proposed in this work. LDCNV calculates the average distance between each read depth (RD) and its
    Language English
    Publishing date 2023-09-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1147761
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Associations of the triglyceride-glucose index and remnant cholesterol with coronary artery disease: a retrospective study.

    Wu, Xiaosheng / Qiu, Weiping / He, Houlin / Zhao, Guojun / Liu, Jianling

    Lipids in health and disease

    2024  Volume 23, Issue 1, Page(s) 45

    Abstract: Background: Remnant cholesterol (RC) represents a low-cost and readily measured lipid index that contributes significantly to residual cardiovascular disease risk. The triglyceride-glucose (TyG) index exhibits a significant correlation with ... ...

    Abstract Background: Remnant cholesterol (RC) represents a low-cost and readily measured lipid index that contributes significantly to residual cardiovascular disease risk. The triglyceride-glucose (TyG) index exhibits a significant correlation with cardiovascular disease occurrence. However, RC and the TyG index have rarely been examined for their potentials in predicting coronary artery disease (CAD). Accordingly, the study was designed to validate the correlations of these two biomarkers with CAD and to compare the forecasted values of these two biomarkers for newly diagnosed CAD.
    Methods: Totally 570 subjects firstly administered coronary angiography were enrolled, including 431 newly diagnosed CAD cases and 139 individuals without CAD. The individuals were classified into two groups according to CAD diagnosis. RC was derived as total cholesterol content (mmol/L) - (high density lipoprotein cholesterol content + low density lipoprotein cholesterol content; both in mmol/L). The TyG index was determined as ln (fasting triglyceride level [mg/dL] × fasting plasma glucose level [mg/dL])/2.
    Results: Baseline feature analysis revealed significant differences in RC and the TyG index between the CAD and non-CAD groups (both P < 0.001). RC and the TyG index were independent risk factors for CAD in accordance with logistic regression analysis (both P < 0.05). Moreover, spearman correlation analysis elucidated CAD had a more remarkable correlation with the TyG index compared with RC (both P < 0.001). Furthermore, according to receiver operating characteristic curve analysis, the TyG index was better than RC in predicting CAD.
    Conclusions: The TyG index and RC have significant associations with CAD. Compared with RC, the TyG index possesses a closer correlation with CAD and a higher predictive value for CAD.
    MeSH term(s) Humans ; Glucose ; Coronary Artery Disease ; Retrospective Studies ; Triglycerides ; Blood Glucose/analysis ; Cardiovascular Diseases/complications ; Risk Factors ; Biomarkers ; Cholesterol
    Chemical Substances Glucose (IY9XDZ35W2) ; Triglycerides ; Blood Glucose ; Biomarkers ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2024-02-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091381-3
    ISSN 1476-511X ; 1476-511X
    ISSN (online) 1476-511X
    ISSN 1476-511X
    DOI 10.1186/s12944-024-02036-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The

    Ruan, Pinglang / Dai, Pei / Mao, Yu / Tang, Zhongxiang / He, Hanlin / Wu, Guojun / Qin, Ling / Tan, Yurong

    Journal of biomolecular structure & dynamics

    2024  , Page(s) 1–12

    Abstract: The insulin-like growth factor 1 receptor (IGF1R) was recognized as a pivotal receptor that facilitated the cellular entry of RSV. Small molecule inhibitors designed to target IGF1R exhibited potential as potent antiviral agents. Through virtual ... ...

    Abstract The insulin-like growth factor 1 receptor (IGF1R) was recognized as a pivotal receptor that facilitated the cellular entry of RSV. Small molecule inhibitors designed to target IGF1R exhibited potential as potent antiviral agents. Through virtual screening, we conducted a screening process involving small molecule compounds derived from natural products, aiming to target the IGF1R protein against respiratory syncytial virus infection. The molecular dynamics simulation analysis showed that tannic acid and daptomycin interacted with the IGF1R. The experimental results
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2024.2309643
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effect of Particle Size and Constraint Conditions on Single Particle Strength of Carbonate Sand.

    He, Yong / Cai, Guojun / Gao, Lei / He, Huan

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 3

    Abstract: Carbonate sand is often encountered and utilized as construction material in offshore engineering projects. Carbonate sand particles, which are porous and angular, are found to be highly crushable under high stress conditions, whereas the mechanisms and ... ...

    Abstract Carbonate sand is often encountered and utilized as construction material in offshore engineering projects. Carbonate sand particles, which are porous and angular, are found to be highly crushable under high stress conditions, whereas the mechanisms and controlling factors for the crushing of carbonate sand particles are not well developed. The crushability and particle strength of around 400 particles from three fractions (5-10 mm, 2-5 mm, and 1-2 mm) of carbonate sand from the South China Sea were investigated via grain-scale single particle crushing tests. Special emphasis was placed on the effect of external constraint conditions (i.e., coordination number) and intrinsic particle morphology characteristics on the particle strength of carbonate soil. The particle strength of carbonate sand was found to be around half of quartz sand in terms of characteristic stress. Negative correlations, which could be depicted by an exponential equation, were found between the particle size and particle strength. Due to elongated particle shape and tensile stress concentration, a higher coordination number may lower the particle strength, which contradicts what was reported for quartz sands. A series of seven fundamental particle dimensions and five particle shape descriptors was characterized, and the aspect ratio was found to be one of the more influential shape descriptors for particle strength. The results enriched the database for the analysis of highly irregular geomaterial and provided insights into controlling factors of particle strength and crushing mechanisms of the carbonate sand.
    MeSH term(s) Carbonates ; Particle Size ; Porosity ; Quartz ; Sand
    Chemical Substances Carbonates ; Sand ; Quartz (14808-60-7)
    Language English
    Publishing date 2022-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22030765
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Feeding behavior of the notorious invasive Mealybug, Phenacoccus solenopsis to exotic weeds using EPG

    Wang, Qianjin / Qi, Guojun / He, Yurong / Lyu, Lihua

    Journal of Asia-Pacific Entomology. 2023 June, v. 26, no. 2 p.102065-

    2023  

    Abstract: The cotton mealybug, Phenacoccus solenopsis Tinsley (Hemiptera: Pseudococcidae) is notorious for causing severe economic losses to a wide range of crop species. It is noteworthy that this mealybug performed different host preference and fitness within ... ...

    Abstract The cotton mealybug, Phenacoccus solenopsis Tinsley (Hemiptera: Pseudococcidae) is notorious for causing severe economic losses to a wide range of crop species. It is noteworthy that this mealybug performed different host preference and fitness within their host range. In order to determine the preference of P. solenopsis between economic plants and weeds, the feeding behavior of cotton mealybug on three widespread exotic weeds belong to Asteraceae family (Bidens pilosa L., Wedelia trilobata and Ambrosia artemisiifolia.) were determined and compared with cotton Gossypium hirsutum L. using electrical penetration graph (EPG). Compared with G. hirsutum, cotton mealybug took the shortest time for trying/detecting on leaf surface and spend the longest duration times for ingestion from phloem bundle tissues feeding on A. artemisiifolia. Results showed that A. artemisiifolia was the most adaptable host for cotton mealybug, B. pilosa and W. trilobata were less suitable ones, implying these plants vulnerable to damage by this mealybug. This consequence gave more evidence for the feeding harm of P. solenopsis and might provide a scientific basis for explain if exotic weeds play an important role in the regional dispersal, and exist as transfer host for pest divert to farmland during uncultivated season.
    Keywords Ambrosia artemisiifolia ; Bidens pilosa ; Gossypium hirsutum ; Phenacoccus solenopsis ; Sphagneticola trilobata ; agricultural land ; cotton ; crops ; entomology ; host preferences ; host range ; ingestion ; leaves ; pests ; phloem ; Phenacoccus solenopsis Tinsley ; Exotic weeds ; Host preference ; EPG
    Language English
    Dates of publication 2023-06
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Pre-press version
    ISSN 1226-8615
    DOI 10.1016/j.aspen.2023.102065
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Insight into the formation of polychlorinated dibenzo-p-dioxins and dibenzofurans in hazardous waste incineration and incinerators: Formation process and reduction strategy.

    He, Fengyu / Wang, Fei / Peng, Yaqi / Cui, Haibin / Lv, Guojun

    Journal of environmental management

    2023  Volume 345, Page(s) 118669

    Abstract: Incineration technology has been widely adopted to safely dispose of hazardous waste (HW). While the incineration process causes the formation of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs). Due to its extreme toxicity, many scholars ... ...

    Abstract Incineration technology has been widely adopted to safely dispose of hazardous waste (HW). While the incineration process causes the formation of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs). Due to its extreme toxicity, many scholars have been committed to determining the PCDD/F formation process and reducing emissions in incinerators. Previous studies ignored the impact of incineration and fluctuation of feeding materials on PCDD/F formation in hazardous waste incinerators (HWIs). In this study, differences in PCDD/F formation between HWIs and municipal solid waste incinerators (MSWIs) were pointed out. The incineration section in HWIs should be carefully considered. Laboratory experiments, conventional analysis and thermogravimetry experiments were conducted. An obvious disparity of PCDD/F formation between 12 kinds of HWs was found. Distillation residue was found with remarkably higher PCDD/F concentrations (11.57 ng/g). Except for the Cl content, aromatic rings and C-O bond organics were also found with high correlation coefficients with PCDD/F concentrations (>0.92). And PCDD/Fs were formed through a chlorination process and structure formation process. All of these are helpful to further understand the PCDD/F formation process during HW incineration, optimize the operation conditions in HWIs and reduce the emission pressure of PCDD/Fs in the future.
    MeSH term(s) Dibenzofurans/analysis ; Incineration ; Polychlorinated Dibenzodioxins/analysis ; Polychlorinated Dibenzodioxins/chemistry ; Dibenzofurans, Polychlorinated/analysis ; Dibenzofurans, Polychlorinated/chemistry ; Hazardous Waste/analysis ; Air Pollutants/analysis ; Environmental Monitoring ; Solid Waste/analysis
    Chemical Substances Dibenzofurans ; Polychlorinated Dibenzodioxins ; Dibenzofurans, Polychlorinated ; Hazardous Waste ; Air Pollutants ; Solid Waste
    Language English
    Publishing date 2023-07-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2023.118669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Using Food Delivery Data to Identify Urban -Rural Areas

    Chunshan Zhou / Xiong He / Runnan Wu / Guojun Zhang

    Frontiers in Earth Science, Vol

    A Case Study of Guangzhou, China

    2022  Volume 10

    Abstract: It is an important task for planners and decision makers to determine whether a certain region is urban or rural since the accurate identification of these areas is of considerable significance to further study differences in urbanization development and ...

    Abstract It is an important task for planners and decision makers to determine whether a certain region is urban or rural since the accurate identification of these areas is of considerable significance to further study differences in urbanization development and balance contradictions between them. However, at present, there are problems of low efficiency and considerable subjectivity in the identification of urban and rural areas based on nighttime light data. Therefore, this study proposes a new method to identify urban and rural areas based on the differences between them. Taking Guangzhou as an example, this study simulated food delivery scenarios to identify urban and rural areas in Guangzhou. The findings indicated that using food delivery data to identify urban and rural areas is highly precise, with an accuracy rate of 92.4% and Kappa value of 0.79. This study provides a new method to identify urban and rural areas accurately and objectively, contributes to the study of urban-rural differences in urbanization and providing a feasible method for subsequent urban and rural planning.
    Keywords spatial planning ; nighttime light data (NTL) ; food delivery ; rrban-rural boundary ; urban expansion ; Science ; Q
    Subject code 910
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Exploring the anti-atherosclerosis mechanism of ginsenoside Rb1 by integrating network pharmacology and experimental verification.

    Hou, Lianjie / Zou, Zhiming / Wang, Yu / Pi, Hui / Yuan, Zeyue / He, Qin / Kuang, Yongfang / Zhao, Guojun

    Aging

    2024  Volume 16, Issue 8, Page(s) 6745–6756

    Abstract: Ginsenoside Rb1 is the major active constituent of ginseng, which is widely used in traditional Chinese medicine for the atherosclerosis treatment by anti-inflammatory, anti-oxidant and reducing lipid accumulation. We explored cellular target and ... ...

    Abstract Ginsenoside Rb1 is the major active constituent of ginseng, which is widely used in traditional Chinese medicine for the atherosclerosis treatment by anti-inflammatory, anti-oxidant and reducing lipid accumulation. We explored cellular target and molecular mechanisms of ginsenoside Rb1 based on network pharmacology and
    MeSH term(s) Ginsenosides/pharmacology ; Atherosclerosis/drug therapy ; Atherosclerosis/metabolism ; Cell Proliferation/drug effects ; Humans ; Protein Interaction Maps ; Molecular Docking Simulation ; Network Pharmacology ; Animals ; Cyclin D1/metabolism ; Cyclin D1/genetics ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Muscle, Smooth, Vascular/cytology ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Mice ; Cyclin-Dependent Kinase 4/metabolism ; Cyclin-Dependent Kinase 4/genetics
    Chemical Substances Ginsenosides ; ginsenoside Rb1 (7413S0WMH6) ; Cyclin D1 (136601-57-5) ; Cyclin-Dependent Kinase 4 (EC 2.7.11.22)
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.205680
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Pleural cryptococcosis diagnosed by pleural biopsy in an immunocompromised patient: a case report.

    Jia, Hongxia / Liu, Hongping / Tu, Meng / Wang, Yan / He, Xudong / Zhang, Guojun

    Frontiers in cellular and infection microbiology

    2023  Volume 13, Page(s) 1258021

    Abstract: Objective: The aim of this study is to report an isolated pleural cryptococcosis with pleural effusion as the only manifestation, confirmed by pleural biopsy in a patient with thymoma combined with myasthenia gravis, who developed pleural effusion of ... ...

    Abstract Objective: The aim of this study is to report an isolated pleural cryptococcosis with pleural effusion as the only manifestation, confirmed by pleural biopsy in a patient with thymoma combined with myasthenia gravis, who developed pleural effusion of unknown origin after long-term glucocorticoids and tacrolimus therapy.
    Methods: Pathological examination of the right pleural biopsy tissue from a patient with unexplained recurrent pleural effusion was implemented. Morphological analysis of the fungal component and metagenomic next-generation sequencing (mNGS) on the pleural tissue were performed.
    Results: A biopsy specimen of the right pleura revealed numerous yeast-like organisms surrounded by mucous capsules and
    Conclusion: Cryptococcosis, manifested by simple pleural effusion, is extremely rare, but when repeated pleural effusion occurs in immunocompromised patients or in patients with malignant tumors, the possibility of cryptococcosis should be treated with high vigilance and pleural biopsy is recommended if necessary in order to confirm the diagnosis.
    MeSH term(s) Humans ; Pleura ; Cryptococcosis/microbiology ; Pleural Effusion ; Biopsy/adverse effects ; Immunocompromised Host
    Language English
    Publishing date 2023-10-25
    Publishing country Switzerland
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2023.1258021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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