LIVIVO - Search results -

Search results

Result 1 - 10 of total 589

Search options

Article ; Online: Xian-Ling-Gu-Bao protects osteoporosis through promoting osteoblast differentiation by targeting miR-100-5p/KDM6B/RUNX2 axis.

Ai, Liang / Yi, Weimin / Chen, Liudan / Wang, Haibin / Huang, Qihui

In vitro cellular & developmental biology. Animal

2021 Volume 57, Issue 1, Page(s) 3–9

MeSH term(s)	Animals ; Cell Differentiation/drug effects ; Cell Differentiation/genetics ; Cell Line ; Core Binding Factor Alpha 1 Subunit/metabolism ; Down-Regulation/drug effects ; Down-Regulation/genetics ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Jumonji Domain-Containing Histone Demethylases/genetics ; Jumonji Domain-Containing Histone Demethylases/metabolism ; Mice ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Osteoblasts/metabolism ; Osteoblasts/pathology ; Osteoporosis/drug therapy ; Osteoporosis/genetics ; Osteoporosis/pathology ; Signal Transduction ; Up-Regulation/drug effects ; Up-Regulation/genetics
Chemical Substances	Core Binding Factor Alpha 1 Subunit ; Drugs, Chinese Herbal ; MIRN100 microRNA, human ; MicroRNAs ; xian ling gu bao ; Jumonji Domain-Containing Histone Demethylases (EC 1.14.11.-) ; KDM6B protein, human (EC 1.14.11.-)
Language	English
Publishing date	2021-01-04
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1077810-x
ISSN	1543-706X ; 0883-8364 ; 1071-2690
ISSN (online)	1543-706X
ISSN	0883-8364 ; 1071-2690
DOI	10.1007/s11626-020-00530-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 851: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾

Article: Corrigendum: Beneficial Effects and Toxicity Studies of Xian-ling-gu-bao on Bone Metabolism in Ovariectomized Rats.

Wu, Hao / Zhong, Qingxiang / Wang, Jing / Wang, Man / Fang, Fang / Xia, Zhi / Zhong, Rongling / Huang, Houcai / Ke, Zhongcheng / Wei, Yingjie / Feng, Liang / Shi, Ziqi / Sun, E / Song, Jie / Jia, Xiaobin

Frontiers in pharmacology

2020 Volume 11, Page(s) 570876

Abstract: This corrects the article DOI: 10.3389/fphar.2017.00273.]. ...

Abstract	[This corrects the article DOI: 10.3389/fphar.2017.00273.].
Language	English
Publishing date	2020-11-09
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2020.570876
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Beneficial Effects and Toxicity Studies of Xian-ling-gu-bao on Bone Metabolism in Ovariectomized Rats.

Frontiers in pharmacology

2017 Volume 8, Page(s) 273

Abstract: Xian-ling-gu-bao (XLGB) is a well-known patented traditional Chinese prescription widely used ...

Abstract	Xian-ling-gu-bao (XLGB) is a well-known patented traditional Chinese prescription widely used to treat osteoporosis, osteoarthritis, aseptic bone necrosis, or climacteric syndrome. However, recent reports have suggested that XLGB may cause liver injury in humans. In the present study, we aimed to evaluate the efficacy of XLGB in the prevention of osteoporosis in the zebrafish and ovariectomized (OVX) rats, both of which have been used as osteoporosis models. The safety of XLGB after long-term administration to OVX rats was also assessed. OVX rats were administered by oral gavage 270 mg/kg (recommended daily dose), 1350 mg/kg, and 1800 mg/kg of XLGB for 26 weeks. Bone mineral density, relative bone surface to bone volume, relative bone volume to total volume, trabecular number, mean trabecular thickness, and mean trabecular spacing in OVX rats were examined at the end of the 26-week dosing period. Additionally, OPG and RANKL expression in the femur were determined by western blot and immunohistochemical staining. To evaluate the safety of XLGB, body weight, hematology, serum biochemistry markers related to toxicology, and organ histopathology were determined in each group of OVX rats. Conversely, the zebrafish was treated with prednisolone to induce osteoporosis in the embryo. Disodium etidronate was used as a treatment control. XLGB was shown to be effective in preventing osteoporosis in both the OVX rats and the prednisolone-treated zebrafish. Similarly, XLGB increased OPG protein and decreased RANKL protein in OVX rats. Interestingly, no obvious toxicity was observed in the heart, liver, kidney, small intestine, or stomach at dosages of up to 1800 mg/kg after treating the OVX rats for 26 weeks. XLGB was shown to be very effective in treating osteoporosis in OVX rats. No obvious toxicity or adverse effects developed in OVX rats at dosages up to 1800 mg/kg, which is equivalent to six times the daily-recommended dose. Therefore, XLGB should be considered a good option for the treatment of post-menopausal osteoporosis.
Language	English
Publishing date	2017-05-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2017.00273
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: [Discussion of novel mode of acupuncture and moxibustion based on identifying the acupoint sensitization].

Chen, Ri-Xin / Huang, Xian-Bao / Xie, Ding-Yi / Li, Hai-Yan

Zhongguo zhen jiu = Chinese acupuncture & moxibustion

2022 Volume 42, Issue 6, Page(s) 665–668

Abstract: On the base of the paradigms of clinical studies on modern moxibustion by identifying the acupoint sensitization, the records of ancient literature in successive dynasties were collected on "identifying the sensitization" of acupoints in acupuncture. In ... ...

Abstract	On the base of the paradigms of clinical studies on modern moxibustion by identifying the acupoint sensitization, the records of ancient literature in successive dynasties were collected on "identifying the sensitization" of acupoints in acupuncture. In association with acupoint detection of acupuncture recorded in current textbooks, a novel concept, "exerting acupuncture by identifying the acupoint sensitization" is proposed. Acupoint sensitization is the common initial link of effect achieved by both acupuncture and moxibustion. Hence, on the basis of the routine acupoint selection by differentiating syndrome, the state of acupoint must be considerably emphasized in either acupuncture or moxibustion. The clinical curative effect may be improved by selecting the sensitized points and identifying sensitization. This novel mode of diagnosis and treatment focuses on identifying acupoint sensitization by unifying acupuncture with moxibustion and in coincidence with the modern clinical characteristics of either acupuncture or moxibustion.
MeSH term(s)	Acupuncture Points ; Acupuncture Therapy ; Moxibustion
Language	Chinese
Publishing date	2022-06-15
Publishing country	China
Document type	Journal Article
ISSN	0255-2930
ISSN	0255-2930
DOI	10.13703/j.0255-2930.20220121-k0001
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: The novel HLA-DQB1*02:01:44 allele, identified by Sanger dideoxy nucleotide sequencing in a Chinese individual.

Zhan, Wen-Qi / Zheng, Zhong-Zheng / Du, Ke-Ming / An, Lin / Huang, Xian-Bao

HLA

2022 Volume 101, Issue 3, Page(s) 301–302

Abstract: HLA-DQB1*02:01:44 differs from HLA-DQB1*02:01:01:01 by one nucleotide in exon 2. ...

Abstract	HLA-DQB102:01:44 differs from HLA-DQB102:01:01:01 by one nucleotide in exon 2.
MeSH term(s)	Humans ; Alleles ; Base Sequence ; East Asian People ; HLA-DQ beta-Chains/genetics ; Nucleotides
Chemical Substances	HLA-DQ beta-Chains ; HLA-DQB1 antigen ; Nucleotides
Language	English
Publishing date	2022-11-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2845111-9
ISSN	2059-2310 ; 2059-2302
ISSN (online)	2059-2310
ISSN	2059-2302
DOI	10.1111/tan.14883
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 661: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: [Application of professor

Huang, Xian-Bao / Chen, Yan-Qi / Xie, Ding-Yi / Chen, Ri-Xin

Zhongguo zhen jiu = Chinese acupuncture & moxibustion

2020 Volume 40, Issue 1, Page(s) 79–83

Abstract: ... ...

Abstract	Professor
MeSH term(s)	Hot Temperature ; Humans ; Medicine, Chinese Traditional ; Moxibustion ; Neoplasms/therapy ; Quality of Life
Language	Chinese
Publishing date	2020-01-12
Publishing country	China
Document type	Journal Article
ISSN	0255-2930
ISSN	0255-2930
DOI	10.13703/j.0255-2930.20190701-k0003
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Essential Trace Element Status in Systemic Lupus Erythematosus: a Meta-analysis Based on Case-Control Studies

Wang, Hua / Li, Xian-Bao / Huang, Rong-Gui / Cao, Nv-Wei / Wu, Hong / Li, Kai-Di / Wang, Yi-Yu / Li, Bao-Zhu

Biol Trace Elem Res. 2023 May, v. 201, no. 5 p.2170-2182

2023

Abstract: The homeostasis of trace elements is essential to regulate different aspects of the immune system and might play important roles in systemic lupus erythematosus (SLE). However, epidemiological evidences that compared the level of essential trace elements ...

Abstract	The homeostasis of trace elements is essential to regulate different aspects of the immune system and might play important roles in systemic lupus erythematosus (SLE). However, epidemiological evidences that compared the level of essential trace elements in SLE patients and healthy controls (HCs) did not reach a consensus. This was the first meta-analysis to comprehensively assess the level of zinc (Zn), copper (Cu), iron (Fe), and selenium (Se) in SLE and HCs. PubMed, Embase, and Web of Science were systematically searched until April 2022 to find relevant literatures. The PRISMA statement 2020 was followed to make sure the quality of reporting a meta-analysis. The outcomes were assessed by pooled standardized mean difference (SMD) and 95% confidence intervals (CIs). Finally, eleven articles with 1262 subjects were included in the meta-analysis. Significantly lower levels of Zn (SMD = −0.709; 95% CI: −1.173, −0.245; P = 0.003) and Fe (SMD = −1.783; 95% CI: −2.756, −0.809; P = 0.000) were found in SLE compared with HCs. Higher levels of Cu (SMD = 0.808; 95% CI: 0.234, 1.382; P = 0.006) were found in SLE patients. In addition, compared with HCs, Fe and Zn were lower in SLE patients in Asia and Cu was higher in SLE patients in Europe. However, no significant difference was observed in the level of Se (SMD = −0.251; 95% CI: −1.087, 0.586; P = 0.557). Above all, SLE patients exhibited lower Zn and Fe and increased Cu concentrations compared with HCs. Further studies are warranted to investigate the mechanism of Zn, Cu, and Fe in SLE patients.
Keywords	copper ; homeostasis ; immune system ; iron ; lupus erythematosus ; meta-analysis ; selenium ; zinc ; Asia ; Europe
Language	English
Dates of publication	2023-05
Size	p. 2170-2182.
Publishing place	Springer US
Document type	Article ; Online
ZDB-ID	445336-0
ISSN	1559-0720 ; 0163-4984
ISSN (online)	1559-0720
ISSN	0163-4984
DOI	10.1007/s12011-022-03335-y
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.B 2323: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Ambient air pollutants increase the risk of immunoglobulin E-mediated allergic diseases: a systematic review and meta-analysis.

Wang, Hua / Li, Xian-Bao / Chu, Xiu-Jie / Cao, Nv-Wei / Wu, Hong / Huang, Rong-Gui / Li, Bao-Zhu / Ye, Dong-Qing

Environmental science and pollution research international

2022 Volume 29, Issue 33, Page(s) 49534–49552

Abstract: Immunoglobulin E (IgE)-mediated allergic diseases, including eczema, atopic dermatitis (AD), and allergic rhinitis (AR), have increased prevalence in recent decades. Recent studies have proved that environmental pollution might have correlations with IgE- ...

Abstract	Immunoglobulin E (IgE)-mediated allergic diseases, including eczema, atopic dermatitis (AD), and allergic rhinitis (AR), have increased prevalence in recent decades. Recent studies have proved that environmental pollution might have correlations with IgE-mediated allergic diseases, but existing research findings were controversial. Thus, we performed a comprehensive meta-analysis from published observational studies to evaluate the risk of long-term and short-term exposure to air pollutants on eczema, AD, and AR in the population (per 10-μg/m
MeSH term(s)	Air Pollutants/analysis ; Air Pollution/analysis ; Eczema/epidemiology ; Environmental Exposure/analysis ; Environmental Pollutants ; Humans ; Immunoglobulin E ; Nitrogen Dioxide/analysis ; Particulate Matter/analysis ; Rhinitis, Allergic/epidemiology
Chemical Substances	Air Pollutants ; Environmental Pollutants ; Particulate Matter ; Immunoglobulin E (37341-29-0) ; Nitrogen Dioxide (S7G510RUBH)
Language	English
Publishing date	2022-05-20
Publishing country	Germany
Document type	Journal Article ; Meta-Analysis ; Review ; Systematic Review
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-20447-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 5915: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Developing a clinical-radiomic prediction model for 3-year cancer-specific survival in lung cancer patients treated with stereotactic body radiation therapy.

Huang, Bao-Tian / Wang, Ying / Lin, Pei-Xian

Journal of cancer research and clinical oncology

2024 Volume 150, Issue 2, Page(s) 34

Abstract: Purpose: The study aims to develop and validate a combined model for predicting 3-year cancer-specific survival (CSS) in lung cancer patients treated with stereotactic body radiation therapy (SBRT) by integrating clinical and radiomic parameters.: ... ...

Abstract	Purpose: The study aims to develop and validate a combined model for predicting 3-year cancer-specific survival (CSS) in lung cancer patients treated with stereotactic body radiation therapy (SBRT) by integrating clinical and radiomic parameters. Methods: Clinical data and pre-treatment CT images were collected from 102 patients treated with lung SBRT. Multivariate logistic regression and the least absolute shrinkage and selection operator were used to determine the clinical and radiomic factors associated with 3-year CSS. Three prediction models were developed using clinical factors, radiomic factors, and a combination of both. The performance of the models was assessed using receiver operating characteristic curve and calibration curve. A nomogram was also created to visualize the 3-year CSS prediction. Results: With a 36-month follow-up, 40 patients (39.2%) died of lung cancer and 62 patients (60.8%) survived. Three clinical factors, including gender, clinical stage, and lymphocyte ratio, along with three radiomic features, were found to be independent factors correlated with 3-year CSS. The area under the curve values for the clinical, radiomic, and combined model were 0.839 (95% CI 0.735-0.914), 0.886 (95% CI 0.790-0.948), and 0.914 (95% CI 0.825-0.966) in the training cohort, and 0.757 (95% CI 0.580-0.887), 0.818 (95% CI 0.648-0.929), and 0.843 (95% CI 0.677-0.944) in the validation cohort, respectively. Additionally, the calibration curve demonstrated good calibration performance and the nomogram created from the combined model showed potential for clinical utility. Conclusion: A clinical-radiomic model was developed to predict the 3-year CSS for lung cancer patients treated with SBRT.
MeSH term(s)	Humans ; Lung Neoplasms/radiotherapy ; Radiomics ; Radiosurgery ; Calibration ; Death
Language	English
Publishing date	2024-01-26
Publishing country	Germany
Document type	Journal Article
ZDB-ID	134792-5
ISSN	1432-1335 ; 0171-5216 ; 0084-5353 ; 0943-9382
ISSN (online)	1432-1335
ISSN	0171-5216 ; 0084-5353 ; 0943-9382
DOI	10.1007/s00432-023-05536-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh III Zs.10: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Endocrine-disrupting chemicals and autoimmune diseases.

Huang, Rong-Gui / Li, Xian-Bao / Wang, Yi-Yu / Wu, Hong / Li, Kai-Di / Jin, Xue / Du, Yu-Jie / Wang, Hua / Qian, Fang-Yi / Li, Bao-Zhu

Environmental research

2023 Volume 231, Issue Pt 2, Page(s) 116222

Abstract: Endocrine-disrupting chemicals (EDCs) widely exist in people's production and life which have great potential to damage human and animal health. Over the past few decades, growing attention has been paid to the impact of EDCs on human health, as well as ... ...

Abstract	Endocrine-disrupting chemicals (EDCs) widely exist in people's production and life which have great potential to damage human and animal health. Over the past few decades, growing attention has been paid to the impact of EDCs on human health, as well as immune system. So far, researchers have proved that EDCs (such as bisphenol A (BPA), phthalate, tetrachlorodibenzodioxin (TCDD), etc.) affect human immune function and promotes the occurrence and development of autoimmune diseases (ADs). Therefore, in order to better understand how EDCs affect ADs, we summarized the current knowledge about the impact of EDCs on ADs, and elaborated the potential mechanism of the impact of EDCs on ADs in this review.
MeSH term(s)	Animals ; Humans ; Endocrine Disruptors/toxicity ; Autoimmune Diseases/chemically induced ; Autoimmune Diseases/epidemiology ; Immune System ; Polychlorinated Dibenzodioxins
Chemical Substances	Endocrine Disruptors ; Polychlorinated Dibenzodioxins
Language	English
Publishing date	2023-05-22
Publishing country	Netherlands
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2023.116222
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 726: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito