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  1. Article ; Online: Corrigendum to "Association between UGS patterns and residents' health status: A report on residents' health in China's old industrial areas" [Environ. Res. 239 (2023) 117199].

    Hou, Yunjing / Chen, Xiyu / Liu, Yiming / Xu, Dawei

    Environmental research

    2024  Volume 252, Issue Pt 1, Page(s) 117892

    Language English
    Publishing date 2024-04-04
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.117892
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    Zs.A 726: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Article ; Online: Cytokine expression patterns: A single-cell RNA sequencing and machine learning based roadmap for cancer classification.

    Ren, Zhixiang / Ren, Yiming / Liu, Pengfei / Xu, Huan

    Computational biology and chemistry

    2024  Volume 109, Page(s) 108025

    Abstract: Cytokines are small protein molecules that exhibit potent immunoregulatory properties, which are known as the essential components of the tumor immune microenvironment (TIME). While some cytokines are known to be universally upregulated in TIME, the ... ...

    Abstract Cytokines are small protein molecules that exhibit potent immunoregulatory properties, which are known as the essential components of the tumor immune microenvironment (TIME). While some cytokines are known to be universally upregulated in TIME, the unique cytokine expression patterns have not been fully resolved in specific types of cancers. To address this challenge, we develop a TIME single-cell RNA sequencing (scRNA-seq) dataset, which is designed to study cytokine expression patterns for precise cancer classification. The dataset, including 39 cancers, is constructed by integrating 684 tumor scRNA-seq samples from multiple public repositories. After screening and processing, the dataset retains only the expression data of immune cells. With a machine learning classification model, unique cytokine expression patterns are identified for various cancer categories and pioneering applied to cancer classification with an accuracy rate of 78.01%. Our method will not only boost the understanding of cancer-type-specific immune modulations in TIME but also serve as a crucial reference for future diagnostic and therapeutic research in cancer immunity.
    MeSH term(s) Humans ; Cytokines/genetics ; Neoplasms/diagnosis ; Neoplasms/genetics ; Sequence Analysis, RNA/methods ; Machine Learning ; Single-Cell Analysis/methods ; Tumor Microenvironment
    Chemical Substances Cytokines
    Language English
    Publishing date 2024-02-06
    Publishing country England
    Document type Journal Article
    ISSN 1476-928X
    ISSN (online) 1476-928X
    DOI 10.1016/j.compbiolchem.2024.108025
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  3. Article ; Online: The importance of interactions between snow, permafrost and vegetation dynamics in affecting terrestrial carbon balance in circumpolar regions

    Yiming Xu / Qianlai Zhuang

    Environmental Research Letters, Vol 18, Iss 4, p

    2023  Volume 044007

    Abstract: Permafrost dynamics can drastically affect vegetation and soil carbon dynamics in northern high latitudes. Vegetation has significant influences on the energy balance of soil surface by impacting the short-wave radiation, long-wave radiation and surface ... ...

    Abstract Permafrost dynamics can drastically affect vegetation and soil carbon dynamics in northern high latitudes. Vegetation has significant influences on the energy balance of soil surface by impacting the short-wave radiation, long-wave radiation and surface sensible heat flux, affecting soil thermal dynamics, in turn, inducing vegetation shift, affecting carbon cycling. During winter, snow can also significantly impact soil temperature due to its insulative effect. However, these processes have not been fully modeled to date. To quantify the interactions between vegetation, snow, and soil thermal dynamics and their impacts on carbon dynamics over the circumpolar region (45–90° N), we revise a sophisticated ecosystem model to improve simulations of soil temperature profile and their influences on vegetation, ecosystem carbon pools and fluxes. We find that, with warmer soil temperature in winter and cooler soil temperature in summer simulated with the revised model considering vegetation shift and snow effects, the region will release 1.54 Pg C/year to the atmosphere for present-day and 66.77–87.95 Pg C in 2022–2100. The canopy effects due to vegetation shift, however, will get more carbon sequestered into the ecosystem at 1.00 Pg C/year for present day and 36.09–44.32 Pg C/year in 2022–2100. This study highlights the importance to consider the interactions between snow, vegetation shift and soil thermal dynamics in simulating carbon dynamics in the region.
    Keywords permafrost ; carbon dynamics ; ecosystem modeling ; land surface process ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350 ; Science ; Q ; Physics ; QC1-999
    Subject code 550
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher IOP Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Rapid Ring-Opening Polymerization of γ-Butyrolactone toward High-Molecular-Weight Poly (γ-butyrolactone) by an Organophosphazene Base and Bisurea Binary Catalyst.

    Liu, Yiming / Xu, Jizhe / Zhang, Yiming / Shen, Yong / Li, Zhibo

    Chemistry, an Asian journal

    2023  Volume 18, Issue 3, Page(s) e202201107

    Abstract: The low temperature condition, long reaction time and associated high energy inputs involved in the polymerization process still hampered the scalable production of poly(γ-butyrolactone) (PγBL) via ring-opening polymerization (ROP) of low strained γBL ... ...

    Abstract The low temperature condition, long reaction time and associated high energy inputs involved in the polymerization process still hampered the scalable production of poly(γ-butyrolactone) (PγBL) via ring-opening polymerization (ROP) of low strained γBL due to its unfavorable thermodynamics. In this contribution, we presented the rapid ROP of γBL using a bisurea in combination with an organophosphazene base as the binary catalyst. Well-defined PγBL samples with various terminal groups were prepared by using different alcohol initiators. The bisurea as a co-catalyst exhibited much higher catalytic activity even compared to the most active monourea in previous report as supported by the kinetic experiments. A moderate monomer conversion of 61% was achieved within 10 mins, producing high-molecular-weight PγBL with M
    Language English
    Publishing date 2023-01-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202201107
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  5. Article: Editorial: Tumor microenvironment targeted nanomedicine: a feasible strategy for cancer imaging and theranostics.

    Xu, Yiming / Jiang, Dawei / Chen, Weiyu

    Frontiers in oncology

    2023  Volume 13, Page(s) 1228910

    Language English
    Publishing date 2023-06-07
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1228910
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  6. Article ; Online: Clinical outcome and survival rate of condylar constrained knee prosthesis in revision total knee arthroplasty: an average nine point six year follow-up.

    Yu, Muyang / Xu, Yiming / Weng, Xisheng / Feng, Bin

    International orthopaedics

    2024  Volume 48, Issue 5, Page(s) 1179–1187

    Abstract: Purpose: Condylar constrained knee prostheses (CCK) are increasingly used in revision total knee arthroplasty (rTKA), but the clinical effectiveness and long-term survival remain a debate. The purpose of this study is to report the long-term clinical ... ...

    Abstract Purpose: Condylar constrained knee prostheses (CCK) are increasingly used in revision total knee arthroplasty (rTKA), but the clinical effectiveness and long-term survival remain a debate. The purpose of this study is to report the long-term clinical and radiographic outcome, implant survival rate, and surgical safety of revision total knee arthroplasty with condylar constrained knee prosthesis.
    Methods: A retrospective cohort study was performed on patients undergoing rTKA with CCK. The cases who received rTKA with CCK from January 2005 to January 2022 were selected. The duration of operation, the estimated perioperative blood loss, and the intraoperative blood transfusion rate were recorded to evaluate surgical safety. The pain visual analog scale (VAS), range of motion (ROM), the Hospital for Special Surgery (HSS) score, the Knee Society Score (KSS), the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), and the Oxford knee score (OKS) was recorded to assess clinical outcome. Standard anteroposterior, lateral, skyline and long-standing AP radiographs of the lower limbs were conducted to assess radiographic outcome. Implant survival was analyzed by Kaplan-Meier survival estimates.
    Results: Fifty-five cases were followed up for an average of 9.6 years (1-18 years), including 16 males and 38 females, with an average age of 66 and an average BMI of 26.9 kg/m
    Conclusion: The use of CCK prosthesis for rTKA can achieve good long-term efficacy and prosthesis survival.
    MeSH term(s) Male ; Female ; Humans ; Aged ; Arthroplasty, Replacement, Knee/adverse effects ; Knee Prosthesis/adverse effects ; Follow-Up Studies ; Retrospective Studies ; Blood Loss, Surgical ; Survival Rate ; Prosthesis Failure ; Treatment Outcome ; Range of Motion, Articular ; Knee Joint/diagnostic imaging ; Knee Joint/surgery
    Language English
    Publishing date 2024-02-14
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80384-4
    ISSN 1432-5195 ; 0341-2695
    ISSN (online) 1432-5195
    ISSN 0341-2695
    DOI 10.1007/s00264-024-06096-6
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1324: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Unlocking access: Addressing the disparities in HPV vaccination for those with mental disorders.

    Yan, Yiming / Xu, Yifeng / Chen, Jianhua

    Asian journal of psychiatry

    2023  Volume 85, Page(s) 103599

    MeSH term(s) Humans ; Papillomavirus Infections ; Patient Acceptance of Health Care ; Vaccination ; Papillomavirus Vaccines ; Health Knowledge, Attitudes, Practice
    Chemical Substances Papillomavirus Vaccines
    Language English
    Publishing date 2023-04-25
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2023.103599
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  8. Article ; Online: Gig worker’s perceived algorithmic management, stress appraisal, and destructive deviant behavior

    Linzi Zhang / Jie Yang / Yiming Zhang / Guohu Xu

    PLoS ONE, Vol 18, Iss

    2023  Volume 11

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: A General Framework for Identifying Hierarchical Interactions and Its Application to Genomics Data.

    Xiao, Zhang / Xingjie, Shi / Yiming, Liu / Xu, Liu / Ma, Shuangge

    Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America

    2023  Volume 32, Issue 3, Page(s) 873–883

    Abstract: The analysis of hierarchical interactions has long been a challenging problem due to the large number of candidate main effects and interaction effects, and the need for accommodating the "main effects, interactions" hierarchy. The two-stage analysis ... ...

    Abstract The analysis of hierarchical interactions has long been a challenging problem due to the large number of candidate main effects and interaction effects, and the need for accommodating the "main effects, interactions" hierarchy. The two-stage analysis methods enjoy simplicity and low computational cost, but contradict the fact that the outcome of interest is attributable to the joint effects of multiple main factors and their interactions. The existing joint analysis methods can accurately describe the underlying data generating process, but suffer from prohibitively high computational cost. And it is not straightforward to extend their optimization algorithms to general loss functions. To address this need, we develop a new computational method that is much faster than the existing joint analysis methods and rivals the runtimes of two-stage analysis. The proposed method, HierFabs, adopts the framework of the forward and backward stagewise algorithm and enjoys computational efficiency and broad applicability. To accommodate hierarchy without imposing additional constraints, it has newly developed forward and backward steps. It naturally accommodates the strong and weak hierarchy, and makes optimization much simpler and faster than in the existing studies. Optimality of HierFabs sequences is investigated theoretically. Simulations show that it outperforms the existing methods. The analysis of TCGA data on melanoma demonstrates its competitive practical performance.
    Language English
    Publishing date 2023-02-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2014382-5
    ISSN 1537-2715 ; 1061-8600
    ISSN (online) 1537-2715
    ISSN 1061-8600
    DOI 10.1080/10618600.2022.2152034
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  10. Article ; Online: Response of soil erosion to climate change and vegetation restoration in the Ganjiang River Basin, China

    Xu He / Zimei Miao / Yiming Wang / Liu Yang / Zenxing Zhang

    Ecological Indicators, Vol 158, Iss , Pp 111429- (2024)

    1481  

    Abstract: In the context of global warming it remains challenging to evaluate declining of soil erosion due to ecological engineering measures, and to isolate and quantify the contributions of various factors involved in soil erosion. For this study, soil erosion ... ...

    Abstract In the context of global warming it remains challenging to evaluate declining of soil erosion due to ecological engineering measures, and to isolate and quantify the contributions of various factors involved in soil erosion. For this study, soil erosion and soil conservation dynamics in the Ganjiang River Basin (GRB) in southeast China were quantitatively assessed based on the Integrated Ecosystem Services and Tradeoff Assessment (InVEST) model. Based on the analysis of the attribution factors of precipitation and Fractional Vegetation Cover (FVC), the dominant factors involved in soil erosion were determined by scenario comparison, where the areas with high sensitivity to erosion were quantitatively identified. The results revealed that both simulated value of soil erosion and sediment export initially decreased and then increased from 2000 to 2020; however, the total increases over the last 20 years were 14 % and 18.18 %, respectively. Moreover, the erosion intensity and sediment delivery ratio (SDR) decreased due to the influence of engineering measures such as reservoirs. Precipitation was the dominant factor that affected GRB soil erosion, with its contribution ratio (40 %-60 %) being as high as 94.74 %. In other words, in the GRB, precipitation inhibited the mitigation effect of high vegetation cover on soil erosion, and the contributions of FVC and precipitation showed a vertical trend. The extremely sensitive area caused by FVC is situated in the economically developed cities along the river system in the middle portion of the basin, while the extremely sensitive area caused by precipitation resides in the middle and upper reaches of the western portion of the basin. Based on this, prioritized protection areas can be determined.
    Keywords Soil erosion ; InVEST model ; Fractional Vegetation Cover(FVC) ; Ganjiang River Basin ; China ; Ecology ; QH540-549.5
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
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