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Article ; Online: Long-term PM

Tsai, Yi-Giien / Chio, Chia-Pin / Yang, Kuender D / Lin, Ching-Hsiung / Yeh, Yen-Po / Chang, Yu-Jun / Chien, Jien-Wen / Wang, Shu-Li / Huang, Shau-Ku / Chan, Chang-Chuan

Pediatric research

2024

Abstract: ... Long-term exposures to PM: Impact: Annual exposure to PM ...

Abstract	Background: Exhaled nitric oxide concentration (FENO) is a marker of airway inflammation. This study aimed to evaluate the association of air pollution exposure with FENO levels and asthma prevalence with respiratory symptoms in school children. Methods: We analyzed 4736 school children who reside in six townships near industrial areas in central Taiwan. We evaluated asthmatic symptoms, FENO, and conducted the environmental questionnaire. The personal exposure of PM Results: Annual exposure to PM Conclusions: Long-term exposures to PM Impact: Annual exposure to PM
Language	English
Publishing date	2024-01-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	4411-8
ISSN	1530-0447 ; 0031-3998
ISSN (online)	1530-0447
ISSN	0031-3998
DOI	10.1038/s41390-023-02977-5
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Article: Short- and long-term results of open

Quan, Ji-Chuan / Zhou, Xin-Jun / Mei, Shi-Wen / Liu, Jun-Guang / Qiu, Wen-Long / Zhang, Jin-Zhu / Li, Bo / Li, Yue-Gang / Wang, Xi-Shan / Chang, Hu / Tang, Jian-Qiang

World journal of gastrointestinal surgery

2023 Volume 15, Issue 9, Page(s) 1969–1977

Abstract: ... term efficacy and long-term prognosis of OMRA as well as LMRA for SCRC located in separate segments ...

Abstract	Background: It remains unclear whether laparoscopic multisegmental resection and anastomosis (LMRA) is safe and advantageous over traditional open multisegmental resection and anastomosis (OMRA) for treating synchronous colorectal cancer (SCRC) located in separate segments. Aim: To compare the short-term efficacy and long-term prognosis of OMRA as well as LMRA for SCRC located in separate segments. Methods: Patients with SCRC who underwent surgery between January 2010 and December 2021 at the Cancer Hospital, Chinese Academy of Medical Sciences and the Peking University First Hospital were retrospectively recruited. In accordance with the inclusion and exclusion criteria, 109 patients who received right hemicolectomy together with anterior resection of the rectum or right hemicolectomy and sigmoid colectomy were finally included in the study. Patients were divided into the LMRA and OMRA groups ( Results: LMRA patients showed markedly less intraoperative blood loss than OMRA patients (100 Conclusion: LMRA is safe and feasible for patients with SCRC located in separate segments. Compared to OMRA, the LMRA approach has more advantages related to short-term efficacy.
Language	English
Publishing date	2023-10-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2573700-4
ISSN	1948-9366
ISSN	1948-9366
DOI	10.4240/wjgs.v15.i9.1969
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Article: Long COVID and rehabilitation.

Chuang, Hung-Jui / Lin, Chia-Wei / Hsiao, Ming-Yen / Wang, Tyng-Guey / Liang, Huey-Wen

Journal of the Formosan Medical Association = Taiwan yi zhi

2023 Volume 123 Suppl 1, Page(s) S61–S69

Abstract: ... known as long COVID. This review examines current knowledge of long COVID, regarding its epidemiology ... for long COVID patients. Dyspnea, chronic cough, and fatigue are the most commonly reported symptoms ... of management of long COVID, can be conducted with different modules, including telerehabilitation. Post ...

Abstract	Coronavirus disease 2019 (COVID-19) has caused tremendous morbidity and mortality worldwide. The large number of post-COVID survivors has drawn attention to the management of post-COVID condition, known as long COVID. This review examines current knowledge of long COVID, regarding its epidemiology, mechanism, and clinical presentations in both adults and children. We also review the rehabilitation principles, modules, and effects, and share Taiwan's efforts to provide a top-down, nationwide care framework for long COVID patients. Dyspnea, chronic cough, and fatigue are the most commonly reported symptoms in the first 6 months after infection, but cognitive impairment and psychological symptoms may persist beyond this time. Several possible mechanisms behind these symptoms were proposed, but remained unconfirmed. These symptoms negatively impact individuals' function, activities, participation and quality of life. Rehabilitation is a key element of management to achieve functional improvement. Early management should start with comprehensive evaluation and identification of red flags. Exercise-based therapy, an essential part of management of long COVID, can be conducted with different modules, including telerehabilitation. Post-exertional symptom exacerbation and orthostatic hypotension should be carefully monitored during exercise. Randomized control trials with a large sample size are needed to determine the optimal timing, dosage, and modules.
MeSH term(s)	Adult ; Child ; Humans ; Post-Acute COVID-19 Syndrome ; COVID-19 ; Quality of Life ; Exercise Therapy ; Dyspnea
Language	English
Publishing date	2023-04-13
Publishing country	Singapore
Document type	Journal Article ; Review
ZDB-ID	2096659-3
ISSN	1876-0821 ; 0929-6646
ISSN (online)	1876-0821
ISSN	0929-6646
DOI	10.1016/j.jfma.2023.03.022
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Article ; Online: New Glycerolipids from the Traditional Chinese Medicine of Syngnathus acus (Hai-Long).

Gao, Zhen / Wang, Meng-Xue / Gao, Cheng-Long / Chen, Sha / Li, Xu-Wen

Chemistry & biodiversity

2023 Volume 20, Issue 6, Page(s) e202300616

Abstract: ... Long). Their structures were elucidated by comprehensive spectral analyses involving UV, IR, MS, 1D and ...

Abstract	Two new glycerolipids, syngaculipids A and B (1 and 2), one first naturally occurring metabolite (8), together with five known compounds (3-7) were isolated from the AcOEt fraction of Syngnathus acus L. (Hai-Long). Their structures were elucidated by comprehensive spectral analyses involving UV, IR, MS, 1D and 2D NMR spectra and ECD calculations. All the isolated compounds were evaluated for their cytotoxicity against A549 and HCT-116 cell lines. Compound 8 exhibited moderate cytotoxicity with IC
MeSH term(s)	Humans ; Medicine, Chinese Traditional ; Molecular Structure ; HCT116 Cells
Language	English
Publishing date	2023-06-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2139001-0
ISSN	1612-1880 ; 1612-1872
ISSN (online)	1612-1880
ISSN	1612-1872
DOI	10.1002/cbdv.202300616
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Article: Clinical characteristics and long

Wei, Qinglin / Li, Wen / Jin, Peng / Sheng, Jianqiu / Li, Shirong / Jia, Yan

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences

2023 Volume 48, Issue 6, Page(s) 852–858

Abstract: Objectives: With the increase in aging population in China, elderly Crohn's disease (CD) patients need to receive more attention. This study aims to explore the clinical characteristics and disease process of elderly onset CD (EOCD) patients in a single ...

Title translation	老年起病克罗恩病的临床特点及远期预后.
Abstract	Objectives: With the increase in aging population in China, elderly Crohn's disease (CD) patients need to receive more attention. This study aims to explore the clinical characteristics and disease process of elderly onset CD (EOCD) patients in a single center. Methods: From January 2002 to January 2022, a total of 221 patients with CD from the Seventh Medical Center of Chinese PLA General Hospital were enrolled. According to the Montreal CD classification standard, the patients were further divided into 4 groups: an EOCD group (≥60 years old, Results: Females were predominant in the EOCD group (15/25, 60%). The number of people without smoking in the EOCD group (80%) was lower than that in COCD group (100%), higher than that in the YOCD group (70.2%) and the MOCD group (69.6%) (all Conclusions: In EOCD patients, females were predominant, smoking was less common, and they were prone to comorbidity. At the initial stage of diagnosis, it is easy to be misdiagnosed as tumor, and the disease behavior mainly showed stricture type, less complicated with perianal diseases. During the follow-up, all-cause mortality and CD-related mortality of EOCD patients were significantly higher than those of the non-elderly onset CD patients.
MeSH term(s)	Female ; Middle Aged ; Humans ; Aged ; Child ; Adult ; Adolescent ; Young Adult ; Crohn Disease/diagnosis ; Crohn Disease/epidemiology ; Prognosis ; Constriction, Pathologic ; Aging ; Hospitals, General
Language	Chinese
Publishing date	2023-08-14
Publishing country	China
Document type	Journal Article
ZDB-ID	2168533-2
ISSN	1672-7347
ISSN	1672-7347
DOI	10.11817/j.issn.1672-7347.2023.230027
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Article ; Online: Long-range photon-efficient 3D imaging without range ambiguity.

Dai, Chen / Ye, Wen-Long / Yu, Chao / Huang, Xin / Li, Zheng-Ping / Xu, Feihu

Optics letters

2023 Volume 48, Issue 6, Page(s) 1542–1545

Abstract: ... which permits the operation of high laser pulse repetition rates for long-range depth imaging without range ...

Abstract	Single-photon light detection and ranging (LiDAR) has broad applications ranging from remote sensing to target recognition. In most cases, however, the repetition period of the pulsed laser limits the maximum distance that can be unambiguously determined. The relative distances are normally obtained using a depth map. Here, we propose and demonstrate a photon-efficient three-dimensional (3D) imaging framework which permits the operation of high laser pulse repetition rates for long-range depth imaging without range ambiguity. Our approach uses only one laser period per pixel and borrows the information from neighboring pixels to reconstruct the absolute depth map of the scene. We demonstrate the absolute depth map recovery at ranges between 2.2 km and 13.8 km using ∼1.41 signal photons per pixel. We also show the capability to image the absolute distances of moving targets in real time.
Language	English
Publishing date	2023-03-22
Publishing country	United States
Document type	Journal Article
ISSN	1539-4794
ISSN (online)	1539-4794
DOI	10.1364/OL.485127
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Article ; Online: Long-range order and quantum criticality in antiferromagnetic chains with long-range staggered interactions.

Ren, Jie / Wang, Zhao / Chen, Weixia / You, Wen-Long

Physical review. E

2022 Volume 105, Issue 3-1, Page(s) 34128

Abstract: ... law decaying long-range interactions. Employing the density-matrix renormalization group (DMRG ... and DMRG in literatures. The deviation is especially evident for strong long-range interactions ... We extend isotropic long-range interactions to the anisotropic cases and find that kaleidoscope of quantum ...

Abstract	We study quantum phase transitions in Heisenberg antiferromagnetic chains with a staggered power-law decaying long-range interactions. Employing the density-matrix renormalization group (DMRG) algorithm and the fidelity susceptibility as the criticality measure, we establish more accurate values of quantum critical points than the results obtained from the spin-wave approximation, quantum Monte Carlo, and DMRG in literatures. The deviation is especially evident for strong long-range interactions. We extend isotropic long-range interactions to the anisotropic cases and find that kaleidoscope of quantum phases emerge from the interplay of anisotropy of the long-range exchange interaction and symmetry breaking. We demonstrate nonfrustrating long-range interactions induce the true long-range order in Heisenberg antiferromagnetic chains with a continuous symmetry breaking, lifting the restrictions imposed by the Mermin-Wagner theorem.
Language	English
Publishing date	2022-04-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2844562-4
ISSN	2470-0053 ; 2470-0045
ISSN (online)	2470-0053
ISSN	2470-0045
DOI	10.1103/PhysRevE.105.034128
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Article ; Online: Establishing chronic models of age-related macular degeneration via long-term iron ion overload.

Huang, Hao / Zeng, Jingshu / Yu, Xinyue / Du, Han / Wen, Chaojuan / Mao, Yan / Tang, Han / Kuang, Xielan / Liu, Wei / Yu, Huan / Liu, Huijun / Li, Bowen / Long, Chongde / Yan, Jianhua / Shen, Huangxuan

American journal of physiology. Cell physiology

2024

Abstract: ... molecular biology were performed. It was demonstrated that long-term treatment of excessive iron ions induced ...

Abstract	Age-related macular degeneration (AMD) is characterized by the degenerative senescence in the retinal pigment epithelium (RPE) and photoreceptors, which is accompanied by the accumulation of iron ions in the aging retina. However, current models of acute oxidative stress are still insufficient to simulate the gradual progression of AMD. To address this, we established chronic injury models by exposing the aRPE-19 cells, 661W cells, and mouse retina to iron ion overload over time. Investigations at the levels of cell biology and molecular biology were performed. It was demonstrated that long-term treatment of excessive iron ions induced senescence-like morphological changes, decreased cell proliferation, and impaired mitochondrial function, contributing to apoptosis. Activation of the mitogen-activated protein kinase (MAPK) pathway and the downstream molecules were confirmed both in the aRPE-19 and 661W cells. Furthermore, iron ion overload resulted in dry AMD-like lesions and decreased visual function in the mouse retina. These findings suggest that chronic exposure to overloading iron ions plays a significant role in the pathogenesis of retinopathy and provide a potential model for future studies on AMD.
Language	English
Publishing date	2024-02-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	392098-7
ISSN	1522-1563 ; 0363-6143
ISSN (online)	1522-1563
ISSN	0363-6143
DOI	10.1152/ajpcell.00532.2023
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Article: Correlation Analysis of the Therapy Adherence to Long-Acting Inhalers Among Patients with Stable COPD.

Tan, Xin / Liu, Shanling / Huang, Li / Wu, Ying / Wen, Long / Liu, Jiheng / Tang, Yuling / Liu, Xiaohui

Patient preference and adherence

2023 Volume 17, Page(s) 1467–1475

Abstract: Purpose: Long-acting inhalers are the mainstay maintenance therapy for stable chronic ... A cross-sectional study was conducted among 246 adult patients with COPD using long-acting inhalers to explore different ...

Abstract	Purpose: Long-acting inhalers are the mainstay maintenance therapy for stable chronic obstructive pulmonary disease (COPD) management. The aim of this study was to assess adherence to inhalers among adults with COPD in China and to develop strategies to improve adherence for the next step. Patients and methods: A cross-sectional study was conducted among 246 adult patients with COPD using long-acting inhalers to explore different demographic characteristics, disease characteristics and medication regimens. Adherence to inhalers was assessed using the Medication Adherence Report Scale (MARS). Results: Among the 246 patients included in the present study, 93 (37.80%) had good adherence, while 153 (62.20%) had poor adherence. From the comparison of patients with good and poor adherence, we found that the course of disease and education background had a significant effect on adherence (p < 0.05). Among the LAMA therapy group, inhaled tiotropium bromide spray (Ingelheim am Rhein, Germany) with active release technology had better adherence than inhaled tiotropium bromide powder (Ingelheim am Rhein, Germany) (p < 0.05). Moreover, COPD patients with good adherence had better pulmonary function and fewer moderate or severe exacerbations in the past year (p < 0.05). Conclusion: The factors affecting the use of inhalers in patients with stable COPD are complicated. Medical staff should select appropriate inhalers according to the patient's disease status and duration and provide medication education to improve adherence.
Language	English
Publishing date	2023-06-17
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2455848-5
ISSN	1177-889X
ISSN	1177-889X
DOI	10.2147/PPA.S413948
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Article ; Online: Long COVID and rehabilitation

Hung-Jui Chuang / Chia-Wei Lin / Ming-Yen Hsiao / Tyng-Guey Wang / Huey-Wen Liang

Journal of the Formosan Medical Association, Vol 123, Iss , Pp S61-S

2024 Volume 69

Abstract	Coronavirus disease 2019 (COVID-19) has caused tremendous morbidity and mortality worldwide. The large number of post-COVID survivors has drawn attention to the management of post-COVID condition, known as long COVID. This review examines current knowledge of long COVID, regarding its epidemiology, mechanism, and clinical presentations in both adults and children. We also review the rehabilitation principles, modules, and effects, and share Taiwan's efforts to provide a top-down, nationwide care framework for long COVID patients. Dyspnea, chronic cough, and fatigue are the most commonly reported symptoms in the first 6 months after infection, but cognitive impairment and psychological symptoms may persist beyond this time. Several possible mechanisms behind these symptoms were proposed, but remained unconfirmed. These symptoms negatively impact individuals' function, activities, participation and quality of life. Rehabilitation is a key element of management to achieve functional improvement. Early management should start with comprehensive evaluation and identification of red flags. Exercise-based therapy, an essential part of management of long COVID, can be conducted with different modules, including telerehabilitation. Post-exertional symptom exacerbation and orthostatic hypotension should be carefully monitored during exercise. Randomized control trials with a large sample size are needed to determine the optimal timing, dosage, and modules.
Keywords	Activities of daily living ; COVID-19 ; Long COVID ; Rehabilitation ; Medicine (General) ; R5-920
Subject code	150
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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