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  1. Article ; Online: Six New Compounds from the Herbaceous Stems of

    Fan, Xiling / Cao, Yangang / Zeng, Mengnan / Ren, Yingjie / Zheng, Xiaoke / Feng, Weisheng

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 2

    Abstract: Six new compounds, ( ... ...

    Abstract Six new compounds, (7
    MeSH term(s) Humans ; Lipopolysaccharides ; Chromans ; Ephedra ; Epithelial Cells
    Chemical Substances Lipopolysaccharides ; Chromans
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29020432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Unlocking the potential of Chinese herbal medicine residue-derived biochar as an efficient adsorbent for high-performance tetracycline removal.

    Zhao, Ziheng / Li, Pengwei / Zhang, Miaomiao / Feng, Weisheng / Tang, Hanxiao / Zhang, Zhijuan

    Environmental research

    2024  Volume 252, Issue Pt 1, Page(s) 118425

    Abstract: This study employed hydrothermal carbonization (HTC) in conjunction with ... ...

    Abstract This study employed hydrothermal carbonization (HTC) in conjunction with ZnCl
    Language English
    Publishing date 2024-02-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2024.118425
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Five new compounds from the stems of Ephedra equisetina.

    Tao, Siqi / Zhu, Denghui / Tie, Qimei / Wu, Yuanyuan / Zhang, Jingke / Zheng, Xiaoke / Feng, Weisheng

    Fitoterapia

    2024  Volume 175, Page(s) 105907

    Abstract: Five new compounds were identified from the stems of Ephedra equisetina Bunge. Their structures were elucidated by spectroscopic methods, involving UV, IR, NMR spectrum and HRESIMS analyses. The absolute configuration of compound 2 was proved by ... ...

    Abstract Five new compounds were identified from the stems of Ephedra equisetina Bunge. Their structures were elucidated by spectroscopic methods, involving UV, IR, NMR spectrum and HRESIMS analyses. The absolute configuration of compound 2 was proved by comparing their experimental and calculated ECD spectrum. The vitro bioactive assay of all compounds suggested that compound 1, 3, 4, 5 and 6 may have potential anti-asthmatic activities.
    Language English
    Publishing date 2024-03-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 412385-2
    ISSN 1873-6971 ; 0367-326X
    ISSN (online) 1873-6971
    ISSN 0367-326X
    DOI 10.1016/j.fitote.2024.105907
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Protective effects of

    Zhang, Jinying / Zhou, Ning / Wang, Yongxiang / Liu, Tong / Cao, Yumin / Feng, Weisheng / Zheng, Xiaoke

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1080962

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1080962
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Self-assembly of amphiphilic asymmetric comb-like copolymers with responsive rigid side chains.

    Li, Zhengyi / Feng, Weisheng / Zhang, Xing / Xu, Binbin / Wang, Liquan / Lin, Shaoliang

    Soft matter

    2024  Volume 20, Issue 12, Page(s) 2823–2830

    Abstract: Amphiphilic asymmetric comb-like copolymers (AACCs) exhibit distinct self-assembly behaviours due to their unique architecture. However, the synthetic difficulties of well-defined AACCs have prohibited a systematic understanding of the architecture- ... ...

    Abstract Amphiphilic asymmetric comb-like copolymers (AACCs) exhibit distinct self-assembly behaviours due to their unique architecture. However, the synthetic difficulties of well-defined AACCs have prohibited a systematic understanding of the architecture-morphology relationship. In this work, we conducted dissipative particle dynamics simulations to investigate the self-assembly behaviours of AACCs with responsive rigid side chains in selective solvents. The effects of side chain length, number of branches, and spacers on the morphology of aggregates were investigated by mapping out morphology diagrams. Besides, the numbers and surface areas of aggregates clearly depicted the morphological transitions during the self-assembly process. Moreover, the rod-to-coil conformation transitions were simulated to explore the stimuli-responsive behaviour of the AACCs with responsive rigid side chains by adjusting the bond angle parameter of the rigid chains. The results indicated that without the support of the rigid chains, the assembly structure collapsed, leading to the tube-to-channelized micelles and one-compartment-to-multicompartment vesicle morphology transformations. The simulation results are consistent with earlier experimental results, which can provide theoretical guidance for assembly toward desired nanostructures.
    Language English
    Publishing date 2024-03-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2191476-X
    ISSN 1744-6848 ; 1744-683X
    ISSN (online) 1744-6848
    ISSN 1744-683X
    DOI 10.1039/d4sm00076e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Flavonoids and phenols from the stems of Ephedra equisetina.

    Tao, Siqi / Zhang, Jingke / Zhu, Denghui / Wu, Yuanyuan / Zheng, Xiaoke / Feng, Weisheng

    Phytochemistry

    2024  Volume 220, Page(s) 114003

    Abstract: Twelve undescribed compounds, including five flavonoids and seven phenols, were isolated from the stems of Ephedra equisetina Bunge. Their structures were elucidated by spectroscopic methods, including NMR spectroscopy and HRESIMS analysis. Their ... ...

    Abstract Twelve undescribed compounds, including five flavonoids and seven phenols, were isolated from the stems of Ephedra equisetina Bunge. Their structures were elucidated by spectroscopic methods, including NMR spectroscopy and HRESIMS analysis. Their absolute configurations were elucidated by comparing their experimental and calculated ECD spectra. In the in vitro bioactive assay, all compounds were tested for their anti-asthmatic activities by releasing β-Hex in C48/80-induced RBL-2H3 cells. The β-Hex release rates of compounds 3, 8, 10, and 11 were 0.8502 ± 0.0231, 0.8802 ± 0.0805, 0.7850 ± 0.0593, and 0.8361 ± 0.0728, respectively, suggesting that compounds 3, 8, 10, and 11 have potential anti-asthmatic activities.
    MeSH term(s) Ephedra sinica/chemistry ; Ephedra/chemistry ; Flavonoids/pharmacology ; Phenols/pharmacology ; Anti-Asthmatic Agents
    Chemical Substances Flavonoids ; Phenols ; Anti-Asthmatic Agents
    Language English
    Publishing date 2024-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 208884-8
    ISSN 1873-3700 ; 0031-9422
    ISSN (online) 1873-3700
    ISSN 0031-9422
    DOI 10.1016/j.phytochem.2024.114003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Biochar Derived from Chinese Herb Medicine Residues for Rhodamine B Dye Adsorption.

    Li, Pengwei / Zhao, Ting / Zhao, Ziheng / Tang, Hanxiao / Feng, Weisheng / Zhang, Zhijuan

    ACS omega

    2023  Volume 8, Issue 5, Page(s) 4813–4825

    Abstract: In this study, one well-known CHM residue ( ...

    Abstract In this study, one well-known CHM residue (
    Language English
    Publishing date 2023-01-27
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c06968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Transcriptome Analysis Provides Insights into Catalpol Biosynthesis in the Medicinal Plant

    Li, Yuanjun / Zhai, Xiaoru / Ma, Ligang / Zhao, Le / An, Na / Feng, Weisheng / Huang, Longyu / Zheng, Xiaoke

    Genes

    2024  Volume 15, Issue 2

    Abstract: Rehmannia ... ...

    Abstract Rehmannia glutinosa
    MeSH term(s) Plants, Medicinal/genetics ; Rehmannia/genetics ; Rehmannia/metabolism ; Gene Expression Profiling ; Acyclic Monoterpenes ; Iridoid Glucosides
    Chemical Substances catalpol (2415-24-9) ; geraniol (L837108USY) ; Acyclic Monoterpenes ; Iridoid Glucosides
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes15020155
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Identification of volatile biomarkers for lung cancer from different histological sources: A comprehensive study.

    Lv, Wei / Shi, Wenmin / Zhang, Zhijuan / Ru, Lihua / Feng, Weisheng / Tang, Hanxiao / Wang, Xiangqi

    Analytical biochemistry

    2024  Volume 690, Page(s) 115527

    Abstract: The identification of noninvasive volatile biomarkers for lung cancer is a significant clinical challenge. Through in vitro studies, the recognition of altered metabolism in cell volatile organic compound (VOC) emitting profile, along with the occurrence ...

    Abstract The identification of noninvasive volatile biomarkers for lung cancer is a significant clinical challenge. Through in vitro studies, the recognition of altered metabolism in cell volatile organic compound (VOC) emitting profile, along with the occurrence of oncogenesis, provides insight into the biochemical pathways involved in the production and metabolism of lung cancer volatile biomarkers. In this research, for the first time, a comprehensive comparative analysis of the volatile metabolites in NSCLS cells (A549), SCLC cells (H446), lung normal cells (BEAS-2B), as well as metabolites in both the oxidative stress (OS) group and control group. Specifically, the combination of eleven VOCs, including n-dodecane, acetaldehyde, isopropylbenzene, p-ethyltoluene and cis-1,3-dichloropropene, exhibited potential as volatile biomarkers for lung cancer originating from two different histological sources. Furthermore, the screening process in A549 cell lines resulted in the identification of three exclusive biomarkers, isopropylbenzene, formaldehyde and bromoform. Similarly, the exclusive biomarkers 1,2,4-trimethylbenzene, p-ethyltoluene, and cis-1,3-dichloropropene were present in the H446 cell line. Additionally, significant changes in trans-2-pentene, acetaldehyde, 1,2,4-trimethylbenzene, and bromoform were observed, indicating a strong association with OS. These findings highlight the potential of volatile biomarkers profiling as a means of noninvasive identification for lung cancer diagnosis.
    Language English
    Publishing date 2024-03-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1110-1
    ISSN 1096-0309 ; 0003-2697
    ISSN (online) 1096-0309
    ISSN 0003-2697
    DOI 10.1016/j.ab.2024.115527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Self-assembly of ABC-type patchy nanoparticles formed by crosslinking triblock copolymer micelles

    Weisheng Feng / Liquan Wang / Xuepei Xu / Xing Zhang / Shaoliang Lin

    Giant, Vol 15, Iss , Pp 100174- (2023)

    2023  

    Abstract: Hierarchical self-assembly is efficient in transferring functionality from small to large scales. Polymer nanoparticles with regularity are highly desirable because they are ideal units of hierarchical self-assembly. Herein, we proposed a crosslinking ... ...

    Abstract Hierarchical self-assembly is efficient in transferring functionality from small to large scales. Polymer nanoparticles with regularity are highly desirable because they are ideal units of hierarchical self-assembly. Herein, we proposed a crosslinking strategy for generating nanoparticles from ABC linear triblock copolymers and conducted a computational study on the self-assembly of the nanoparticles. The effect of nanoparticle symmetry on aggregation behaviors was examined. We found that the symmetric patchy nanoparticles can form various low-curvature aggregates tuned by the crosslinking numbers and A/C block lengths. Increasing the asymmetry of patchy nanoparticles causes the increased curvature of assemblies, forming well-defined structures such as loops, vesicles, and wavy ribbons. Furthermore, the self-assembly kinetics reveals a step-growth nature, resembling the step polymerization for one-dimensional growth. The work demonstrates that ABC-type polymeric nanoparticles are versatile units for building hierarchical assemblies, considerably enriching the self-assembly strategies.
    Keywords Self-assembly ; Patchy nanoparticles ; Copolymer ; Hierarchical assemblies ; Dissipative particle dynamics ; Science (General) ; Q1-390
    Subject code 000
    Language English
    Publishing date 2023-08-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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