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  1. Book ; Online ; E-Book: Advanced polymers in medicine

    Puoci, Francesco

    2015  

    Author's details Francesco Puoci ed
    Keywords Polymers / therapeutic use ; Biomedical Engineering / methods ; Chemistry ; Polymers ; Pharmacy ; Biochemistry ; Biomaterials
    Subject code 541.2254
    Language English
    Size VIII, 537 S. : Ill.
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT018834718
    ISBN 978-3-319-12478-0 ; 978-3-319-12477-3 ; 3-319-12478-1 ; 3-319-12477-3
    DOI 10.1007/978-3-319-12478-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: "Monoclonal-Type" Plastic Antibodies for COVID-19 Treatment: What Is the Idea?

    Puoci, Francesco

    Journal of functional biomaterials

    2020  Volume 11, Issue 2

    Abstract: In late December 2019, an outbreak due to a novel coronavirus, initially called 2019-nCoV, was reported in Wuhan, China [ ... ]. ...

    Abstract In late December 2019, an outbreak due to a novel coronavirus, initially called 2019-nCoV, was reported in Wuhan, China [...].
    Keywords covid19
    Language English
    Publishing date 2020-06-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2648525-4
    ISSN 2079-4983
    ISSN 2079-4983
    DOI 10.3390/jfb11020043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of a Multi-Strain Probiotic Supplementation to Manage Stress during the COVID-19 Pandemic: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial.

    Nobile, Vincenzo / Puoci, Francesco

    Neuropsychobiology

    2023  Volume 82, Issue 2, Page(s) 61–71

    Abstract: Introduction: The COVID-19 pandemic strongly affected every aspect of the modern society, from health to socioeconomics, leading people to experience high levels of stress.: Methods: A double-blind, cross-over, placebo-controlled clinical study was ... ...

    Abstract Introduction: The COVID-19 pandemic strongly affected every aspect of the modern society, from health to socioeconomics, leading people to experience high levels of stress.
    Methods: A double-blind, cross-over, placebo-controlled clinical study was performed to investigate the ability of a food supplement containing two probiotic strains, Limosilactobacillus reuteri PBS072 and Bifidobacterium breve BB077, in supporting 33 healthy adults, working at a university, in stress management. The efficacy of the tested strains in influencing the stress response, in terms of mood and sleep behavior, was assessed using the following validated questionnaires: Profile of Mood State (POMS) and Pittsburgh Sleep Quality Index (PSQI).
    Results: Outcomes of the POMS and the PSQI demonstrated a significant reduction of the questionnaire's scores both versus baseline and placebo after 30 days of probiotic intake.
    Conclusions: According to the results, the probiotic food supplement investigated showed a remarkable effect on stress management by improving the quality of sleep and the mood.
    MeSH term(s) Adult ; Humans ; Pandemics ; COVID-19 ; Probiotics/therapeutic use ; Dietary Supplements ; Affect ; Double-Blind Method
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 442239-9
    ISSN 1423-0224 ; 0302-282X
    ISSN (online) 1423-0224
    ISSN 0302-282X
    DOI 10.1159/000527956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: “Monoclonal-Type” Plastic Antibodies for COVID-19 Treatment

    Francesco Puoci

    Journal of Functional Biomaterials, Vol 11, Iss 43, p

    What Is the Idea?

    2020  Volume 43

    Abstract: In late December 2019, an outbreak due to a novel coronavirus, initially called 2019-nCoV, was reported in Wuhan, China [.] ...

    Abstract In late December 2019, an outbreak due to a novel coronavirus, initially called 2019-nCoV, was reported in Wuhan, China [.]
    Keywords n/a ; Biotechnology ; TP248.13-248.65 ; Medicine (General) ; R5-920 ; covid19
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: "Monoclonal-Type" Plastic Antibodies for COVID-19 Treatment: What Is the Idea?

    Puoci, Francesco

    Abstract: In late December 2019, an outbreak due to a novel coronavirus, initially called 2019-nCoV, was reported in Wuhan, China [ ... ]. ...

    Abstract In late December 2019, an outbreak due to a novel coronavirus, initially called 2019-nCoV, was reported in Wuhan, China [...].
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #601323
    Database COVID19

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  6. Article: Natural and Synthetic Polymeric Biomaterials for Application in Wound Management.

    Prete, Sabrina / Dattilo, Marco / Patitucci, Francesco / Pezzi, Giuseppe / Parisi, Ortensia Ilaria / Puoci, Francesco

    Journal of functional biomaterials

    2023  Volume 14, Issue 9

    Abstract: Biomaterials are at the forefront of the future, finding a variety of applications in the biomedical field, especially in wound healing, thanks to their biocompatible and biodegradable properties. Wounds spontaneously try to heal through a series of ... ...

    Abstract Biomaterials are at the forefront of the future, finding a variety of applications in the biomedical field, especially in wound healing, thanks to their biocompatible and biodegradable properties. Wounds spontaneously try to heal through a series of interconnected processes involving several initiators and mediators such as cytokines, macrophages, and fibroblasts. The combination of biopolymers with wound healing properties may provide opportunities to synthesize matrices that stimulate and trigger target cell responses crucial to the healing process. This review outlines the optimal management and care required for wound treatment with a special focus on biopolymers, drug-delivery systems, and nanotechnologies used for enhanced wound healing applications. Researchers have utilized a range of techniques to produce wound dressings, leading to products with different characteristics. Each method comes with its unique strengths and limitations, which are important to consider. The future trajectory in wound dressing advancement should prioritize economical and eco-friendly methodologies, along with improving the efficacy of constituent materials. The aim of this work is to give researchers the possibility to evaluate the proper materials for wound dressing preparation and to better understand the optimal synthesis conditions as well as the most effective bioactive molecules to load.
    Language English
    Publishing date 2023-09-03
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2648525-4
    ISSN 2079-4983
    ISSN 2079-4983
    DOI 10.3390/jfb14090455
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Polysaccharide-Based Hydrogels and Their Application as Drug Delivery Systems in Cancer Treatment: A Review.

    Dattilo, Marco / Patitucci, Francesco / Prete, Sabrina / Parisi, Ortensia Ilaria / Puoci, Francesco

    Journal of functional biomaterials

    2023  Volume 14, Issue 2

    Abstract: Hydrogels are three-dimensional crosslinked structures with physicochemical properties similar to the extracellular matrix (ECM). By changing the hydrogel's material type, crosslinking, molecular weight, chemical surface, and functionalization, it is ... ...

    Abstract Hydrogels are three-dimensional crosslinked structures with physicochemical properties similar to the extracellular matrix (ECM). By changing the hydrogel's material type, crosslinking, molecular weight, chemical surface, and functionalization, it is possible to mimic the mechanical properties of native tissues. Hydrogels are currently used in the biomedical and pharmaceutical fields for drug delivery systems, wound dressings, tissue engineering, and contact lenses. Lately, research has been focused on hydrogels from natural sources. Polysaccharides have drawn attention in recent years as a promising material for biological applications, due to their biocompatibility, biodegradability, non-toxicity, and excellent mechanical properties. Polysaccharide-based hydrogels can be used as drug delivery systems for the efficient release of various types of cancer therapeutics, enhancing the therapeutic efficacy and minimizing potential side effects. This review summarizes hydrogels' classification, properties, and synthesis methods. Furthermore, it also covers several important natural polysaccharides (chitosan, alginate, hyaluronic acid, cellulose, and carrageenan) widely used as hydrogels for drug delivery and, in particular, their application in cancer treatment.
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2648525-4
    ISSN 2079-4983
    ISSN 2079-4983
    DOI 10.3390/jfb14020055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: 3D-Printed Alginate/Pectin-Based Patches Loaded with Olive Leaf Extracts for Wound Healing Applications: Development, Characterization and In Vitro Evaluation of Biological Properties.

    Patitucci, Francesco / Motta, Marisa Francesca / Dattilo, Marco / Malivindi, Rocco / Leonetti, Adele Elisabetta / Pezzi, Giuseppe / Prete, Sabrina / Mileti, Olga / Gabriele, Domenico / Parisi, Ortensia Ilaria / Puoci, Francesco

    Pharmaceutics

    2024  Volume 16, Issue 1

    Abstract: Traditional wound dressings may lack suitability for diverse wound types and individual patient requirements. In this context, this study aimed to innovate wound care by developing a 3D-printed patch using alginate and pectin and incorporating Olive Leaf ...

    Abstract Traditional wound dressings may lack suitability for diverse wound types and individual patient requirements. In this context, this study aimed to innovate wound care by developing a 3D-printed patch using alginate and pectin and incorporating Olive Leaf Extract (OLE) as an active ingredient. Different polymer-to-plasticizer ratios were systematically examined to formulate a printable ink with optimal viscosity. The resultant film, enriched with OLE, exhibited a substantial polyphenolic content of 13.15 ± 0.41 mg CAE/g, showcasing significant antioxidant and anti-inflammatory properties. Notably, the film demonstrated potent scavenging abilities against DPPH, ABTS, and NO radicals, with IC
    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics16010099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A Randomized, Double-Blind, Placebo-Controlled Trial: Efficacy of

    Mellai, Marta / Allesina, Marta / Edoardo, Benedetto / Cascella, Federica / Nobile, Vincenzo / Spina, Amelia / Amone, Fabio / Zaccaria, Vincenzo / Insolia, Violetta / Perri, Anna / Lofaro, Danilo / Puoci, Francesco

    Nutrients

    2024  Volume 16, Issue 5

    Abstract: Gut dysbiosis refers to an imbalance in gut microbiota composition and function. ...

    Abstract Gut dysbiosis refers to an imbalance in gut microbiota composition and function.
    MeSH term(s) Adult ; Humans ; Prebiotics ; Opuntia ; Dysbiosis/microbiology ; Feces/microbiology ; Bacteria ; Double-Blind Method
    Chemical Substances Prebiotics
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16050586
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Natural and Synthetic Polymeric Biomaterials for Application in Wound Management

    Sabrina Prete / Marco Dattilo / Francesco Patitucci / Giuseppe Pezzi / Ortensia Ilaria Parisi / Francesco Puoci

    Journal of Functional Biomaterials, Vol 14, Iss 455, p

    2023  Volume 455

    Abstract: Biomaterials are at the forefront of the future, finding a variety of applications in the biomedical field, especially in wound healing, thanks to their biocompatible and biodegradable properties. Wounds spontaneously try to heal through a series of ... ...

    Abstract Biomaterials are at the forefront of the future, finding a variety of applications in the biomedical field, especially in wound healing, thanks to their biocompatible and biodegradable properties. Wounds spontaneously try to heal through a series of interconnected processes involving several initiators and mediators such as cytokines, macrophages, and fibroblasts. The combination of biopolymers with wound healing properties may provide opportunities to synthesize matrices that stimulate and trigger target cell responses crucial to the healing process. This review outlines the optimal management and care required for wound treatment with a special focus on biopolymers, drug-delivery systems, and nanotechnologies used for enhanced wound healing applications. Researchers have utilized a range of techniques to produce wound dressings, leading to products with different characteristics. Each method comes with its unique strengths and limitations, which are important to consider. The future trajectory in wound dressing advancement should prioritize economical and eco-friendly methodologies, along with improving the efficacy of constituent materials. The aim of this work is to give researchers the possibility to evaluate the proper materials for wound dressing preparation and to better understand the optimal synthesis conditions as well as the most effective bioactive molecules to load.
    Keywords wound healing ; wound management ; dressings ; biopolymers ; natural polymers ; synthetic polymers ; Biotechnology ; TP248.13-248.65 ; Medicine (General) ; R5-920
    Subject code 540
    Language English
    Publishing date 2023-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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