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  1. Article ; Online: S

    Sun, Junyi / Xie, Zhengshuo / Ye, Min / Xu, He / Dong, Yugang / Liu, Chen / Zhu, Wengen

    ESC heart failure

    2024  

    Abstract: Aims: This study investigated the S: Methods and results: Analysing 890 GUIDE-IT HFrEF trial ... participants, we stratified them by baseline S: Conclusions: The S ...

    Abstract Aims: This study investigated the S
    Methods and results: Analysing 890 GUIDE-IT HFrEF trial participants, we stratified them by baseline S
    Conclusions: The S
    Language English
    Publishing date 2024-02-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2814355-3
    ISSN 2055-5822 ; 2055-5822
    ISSN (online) 2055-5822
    ISSN 2055-5822
    DOI 10.1002/ehf2.14689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: S

    Fang, Wen / Luo, Zhi-Wen / Wang, Ye-Cheng / Zhou, Wei / Li, Lei / Chen, Yimin / Zhang, Xiangke / Dai, Mingji / Dai, Jian-Jun

    Angewandte Chemie (International ed. in English)

    2024  Volume 63, Issue 14, Page(s) e202317570

    Abstract: ... organic chemistry. Despite the substantial advances in bimolecular nucleophilic substitutions (S ...

    Abstract Nucleophilic substitutions are fundamentally important transformations in synthetic organic chemistry. Despite the substantial advances in bimolecular nucleophilic substitutions (S
    Language English
    Publishing date 2024-03-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202317570
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: s

    Chen, Tao / Xiao, Guangjun / Wang, Zhuo / Zou, Jian / Wang, Jian / Hu, Weibo / Liu, Yahu A / Yang, Hui / Wen, Ke

    ACS omega

    2022  Volume 7, Issue 13, Page(s) 11276–11284

    Abstract: Integrating fluorescent chromophores in aromatic frameworks could not only prevent aggregation-induced quenching caused by the π-π stacking interaction between the chromophore components but also confer new fluorescence properties. Herein, we report the ... ...

    Abstract Integrating fluorescent chromophores in aromatic frameworks could not only prevent aggregation-induced quenching caused by the π-π stacking interaction between the chromophore components but also confer new fluorescence properties. Herein, we report the fabrication of
    Language English
    Publishing date 2022-03-23
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c00278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: S

    Karimova, Natalia V / Chen, James / Gord, Joseph R / Staudt, Sean / Bertram, Timothy H / Nathanson, Gilbert M / Gerber, R Benny

    The journal of physical chemistry. A

    2020  Volume 124, Issue 4, Page(s) 711–720

    Abstract: Reactions of dinitrogen pentoxide ( ... ...

    Abstract Reactions of dinitrogen pentoxide (N
    Language English
    Publishing date 2020-01-22
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.9b09095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: S

    Yang, Jie / Zhang, Hong / Gong, Weibin / Liu, Zhenyan / Wu, Huiwen / Hu, Wanhui / Chen, Xinxin / Wang, Lei / Wu, Si / Chen, Chang / Perrett, Sarah

    The Journal of biological chemistry

    2020  Volume 295, Issue 24, Page(s) 8302–8324

    Abstract: Heat shock protein 70 (Hsp70) proteins are a family of ancient and conserved chaperones. Cysteine modifications have been widely detected among different Hsp70 family ... ...

    Abstract Heat shock protein 70 (Hsp70) proteins are a family of ancient and conserved chaperones. Cysteine modifications have been widely detected among different Hsp70 family members
    MeSH term(s) Binding Sites ; Biotin/metabolism ; Cysteine/metabolism ; Glutathione/metabolism ; HSP70 Heat-Shock Proteins/chemistry ; HSP70 Heat-Shock Proteins/genetics ; HSP70 Heat-Shock Proteins/metabolism ; HeLa Cells ; Humans ; Magnetic Resonance Spectroscopy ; Mutant Proteins/chemistry ; Mutant Proteins/metabolism ; Mutation/genetics ; Peptides/chemistry ; Peptides/metabolism ; Protein Stability ; Protein Structure, Secondary ; Protein Unfolding ; Structure-Activity Relationship ; Substrate Specificity
    Chemical Substances HSP70 Heat-Shock Proteins ; Mutant Proteins ; Peptides ; Biotin (6SO6U10H04) ; Glutathione (GAN16C9B8O) ; Cysteine (K848JZ4886)
    Language English
    Publishing date 2020-04-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1074/jbc.RA119.012372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.108: Show issues Location:
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  6. Article: S

    Deng, Shuilin / Chen, Haohua / Ma, Xingxing / Zhou, Yao / Yang, Kai / Lan, Yu / Song, Qiuling

    Chemical science

    2019  Volume 10, Issue 28, Page(s) 6828–6833

    Abstract: An unprecedented S ...

    Abstract An unprecedented S
    Language English
    Publishing date 2019-06-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/c9sc01333d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: S

    Qi, Feilong / Zhang, Chen / Jiang, Shanshan / Wang, Qian / Kuerban, Kudelaidi / Luo, Man / Dong, Mengxue / Zhou, Xinguang / Wu, Laiming / Jiang, Biao / Ye, Li

    Bioscience reports

    2019  Volume 39, Issue 6

    Abstract: Allicin can be used as fumigant to protect food and cultural relics from fungal contamination because of its strong antifungal activity and the characteristics of high volatility and no residues. However, the obvious disadvantages such as high minimal ... ...

    Abstract Allicin can be used as fumigant to protect food and cultural relics from fungal contamination because of its strong antifungal activity and the characteristics of high volatility and no residues. However, the obvious disadvantages such as high minimal inhibitory concentration and instability prevent it from wide application. In this study, a stable derivative of allicin,
    MeSH term(s) Apoptosis/drug effects ; Oxidative Stress/drug effects ; Penicillium chrysogenum/metabolism ; Sulfinic Acids/pharmacology
    Chemical Substances Sulfinic Acids ; allicin (3C39BY17Y6)
    Language English
    Publishing date 2019-06-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 764946-0
    ISSN 1573-4935 ; 0144-8463
    ISSN (online) 1573-4935
    ISSN 0144-8463
    DOI 10.1042/BSR20190167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1676: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  8. Article ; Online: S

    Zhang, Jie / Ye, Zhi-Wei / Chen, Wei / Manevich, Yefim / Mehrotra, Shikhar / Ball, Lauren / Janssen-Heininger, Yvonne / Tew, Kenneth D / Townsend, Danyelle M

    The Journal of biological chemistry

    2018  Volume 293, Issue 12, Page(s) 4366–4380

    Abstract: ... ...

    Abstract Glutathione
    MeSH term(s) Animals ; Cell Proliferation ; Dendritic Cells/cytology ; Dendritic Cells/physiology ; Estrogen Receptor alpha/metabolism ; Glutathione/metabolism ; Glutathione S-Transferase pi/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Oxidative Stress ; Protein Processing, Post-Translational ; Reactive Oxygen Species/metabolism ; Signal Transduction
    Chemical Substances Estrogen Receptor alpha ; Gstp2 protein, mouse ; Reactive Oxygen Species ; Glutathione S-Transferase pi (EC 2.5.1.18) ; Gstp1 protein, mouse (EC 2.5.1.18) ; Glutathione (GAN16C9B8O)
    Language English
    Publishing date 2018-01-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1074/jbc.M117.814327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.108: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  9. Article ; Online: S

    Qian, Qingwen / Zhang, Zeyuan / Orwig, Allyson / Chen, Songhai / Ding, Wen-Xing / Xu, Yanji / Kunz, Ryan C / Lind, Nicholas R L / Stamler, Jonathan S / Yang, Ling

    Diabetes

    2017  Volume 67, Issue 2, Page(s) 193–207

    Abstract: Obesity is associated with elevated intracellular nitric oxide (NO) production, which promotes nitrosative stress in metabolic tissues such as liver and skeletal muscle, contributing to insulin resistance. The onset of obesity-associated insulin ... ...

    Abstract Obesity is associated with elevated intracellular nitric oxide (NO) production, which promotes nitrosative stress in metabolic tissues such as liver and skeletal muscle, contributing to insulin resistance. The onset of obesity-associated insulin resistance is due, in part, to the compromise of hepatic autophagy, a process that leads to lysosomal degradation of cellular components. However, it is not known how NO bioactivity might impact autophagy in obesity. Here, we establish that
    MeSH term(s) Alcohol Dehydrogenase/chemistry ; Alcohol Dehydrogenase/genetics ; Alcohol Dehydrogenase/metabolism ; Aldehyde Oxidoreductases/chemistry ; Aldehyde Oxidoreductases/genetics ; Aldehyde Oxidoreductases/metabolism ; Animals ; Autophagy ; Cells, Cultured ; Cysteine/metabolism ; Diabetes Mellitus/enzymology ; Diabetes Mellitus/metabolism ; Diabetes Mellitus/pathology ; Diet, High-Fat/adverse effects ; Gene Expression Regulation, Enzymologic ; Green Fluorescent Proteins/chemistry ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Hepatocytes/enzymology ; Hepatocytes/metabolism ; Hepatocytes/pathology ; Humans ; Insulin Resistance ; Lysosomes/enzymology ; Lysosomes/metabolism ; Lysosomes/pathology ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Nitrosative Stress ; Non-alcoholic Fatty Liver Disease/enzymology ; Non-alcoholic Fatty Liver Disease/metabolism ; Non-alcoholic Fatty Liver Disease/pathology ; Obesity/etiology ; Obesity/metabolism ; Obesity/pathology ; Obesity/physiopathology ; Protein Processing, Post-Translational ; Recombinant Fusion Proteins
    Chemical Substances Recombinant Fusion Proteins ; enhanced green fluorescent protein ; Green Fluorescent Proteins (147336-22-9) ; Adh5 protein, mouse (EC 1.1.1.1) ; Alcohol Dehydrogenase (EC 1.1.1.1) ; Aldehyde Oxidoreductases (EC 1.2.-) ; formaldehyde dehydrogenase, glutathione-independent (EC 1.2.1.46) ; Cysteine (K848JZ4886)
    Language English
    Publishing date 2017-10-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80085-5
    ISSN 1939-327X ; 0012-1797
    ISSN (online) 1939-327X
    ISSN 0012-1797
    DOI 10.2337/db17-0223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.175: Show issues Location:
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  10. Article ; Online: S

    Duncan, Peter J / Bi, Danlei / McClafferty, Heather / Chen, Lie / Tian, Lijun / Shipston, Michael J

    The Journal of biological chemistry

    2019  Volume 294, Issue 32, Page(s) 12066–12076

    Abstract: The properties and physiological function of pore-forming α-subunits of large conductance calcium- and voltage-activated potassium (BK) channels are potently modified by their functional coupling with regulatory subunits in many tissues. However, ... ...

    Abstract The properties and physiological function of pore-forming α-subunits of large conductance calcium- and voltage-activated potassium (BK) channels are potently modified by their functional coupling with regulatory subunits in many tissues. However, mechanisms that might control functional coupling are very poorly understood. Here we show that
    MeSH term(s) Acylation ; Animals ; Cells, Cultured ; HEK293 Cells ; Humans ; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits/genetics ; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits/metabolism ; Large-Conductance Calcium-Activated Potassium Channel beta Subunits/genetics ; Large-Conductance Calcium-Activated Potassium Channel beta Subunits/metabolism ; Large-Conductance Calcium-Activated Potassium Channels/genetics ; Large-Conductance Calcium-Activated Potassium Channels/metabolism ; Male ; Membrane Proteins/deficiency ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/metabolism ; Patch-Clamp Techniques ; Sulfur/metabolism
    Chemical Substances GODZ protein, mouse ; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits ; Large-Conductance Calcium-Activated Potassium Channel beta Subunits ; Large-Conductance Calcium-Activated Potassium Channels ; Membrane Proteins ; Sulfur (70FD1KFU70)
    Language English
    Publishing date 2019-06-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2997-x
    ISSN 1083-351X ; 0021-9258
    ISSN (online) 1083-351X
    ISSN 0021-9258
    DOI 10.1074/jbc.RA119.009065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.108: Show issues Location:
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