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Article ; Online: Genetic Characterization of Two Human Cases Infected with the Avian Influenza A (H5N6) Viruses - Guangxi Zhuang Autonomous Region, China, 2021.

Bi, Fuyin / Jiang, Lili / Huang, Lihua / Wei, Jingguang / Pan, Xiaowen / Ju, Yu / Mo, Jianjun / Chen, Minmei / Kang, Ning / Tan, Yi / Li, Yonghong / Wang, Jing

China CDC weekly

2021 Volume 3, Issue 44, Page(s) 923–928

Abstract: What is known about this topic?: H5N6 has replaced H5N1 as a dominant avian influenza virus (AIV) subtype in southern China. The increasing genetic diversity and geographical distribution of H5N6 pose a serious threat to the poultry industry and human ... ...

Abstract	What is known about this topic?: H5N6 has replaced H5N1 as a dominant avian influenza virus (AIV) subtype in southern China. The increasing genetic diversity and geographical distribution of H5N6 pose a serious threat to the poultry industry and human health. What is added by this report?: A total of 2 cases of H5N6 that occurred from February 2021 to July 2021 in Guangxi, China were reported in this study. Phylogenetic analysis of gene was constructed, and some mutations of HA gene, PB2 gene, PA gene, M1 gene, NS1 gene, the receptor-binding site were detected. The evolutionary origins of the internal genes were different. What are the implications for public health practice?: As a multi-source reassortant virus, the H5N6 highly pathogenic AIV is continuously evolving. There is an urgent need to strengthen the surveillance of drug-resistant strains and novel variants.
Language	English
Publishing date	2021-10-28
Publishing country	China
Document type	Journal Article
ISSN	2096-7071
ISSN (online)	2096-7071
DOI	10.46234/ccdcw2021.199
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Zhuang Gu Guan Jie Wan

Bin Liu / Danping Fan / Wen Sun / Kang Zheng / Guoming Pang / Xiaojuan He / Cheng Xiao / Cheng Lu

Evidence-Based Complementary and Alternative Medicine, Vol

Reasonable Application Can Alleviate the Liver Injury for Osteoarthritis Treatment

2018 Volume 2018

Abstract: ... Chinese patent medicine, Zhuang Gu Guan Jie Wan (ZGGJW) has been brought into focus recently ...

Abstract	The potential toxicity of herbal drugs, particularly drug-induced liver injury (DILI), has received extensive attention as the use of Chinese herbal medicine has rapidly increased globally. As a classic Chinese patent medicine, Zhuang Gu Guan Jie Wan (ZGGJW) has been brought into focus recently because of its satisfactory therapeutic effects on osteoarthritis (OA) as well as its unanticipated side effects. This study aimed to decipher the puzzling phenomenon of liver injury developing in response to ZGGJW that varies by the subtype of OA. Normal, anterior cruciate ligament transaction (ACLT) and partial medial meniscectomy (MMx) induced OA and ovariectomy combined with ACLT and partial MMx induced rat models were used and treated orally with ZGGJW or distilled water for 30 days. The results from histopathology, biochemistry, and immunohistochemistry showed that ZGGJW induced liver injury, increased the level of malondialdehyde (MDA), and decreased the levels of total antioxidation capability (T-AOC), superoxide dismutase (SOD), interleukin-22 (IL-22), and signal transducer and activator of transcription factor 3 (STAT3) in the liver of normal rats, while liver injury was alleviated and showed different tendencies in the above markers for ACLT and partial MMx induction rats and ovariectomy combined with ACLT and partial MMx induction rats after ZGGJW treatment. In the OA disease states, hepatic injury induced by ZGGJW could be associated with an impairment in antioxidant capacity and the high levels of IL-22 and STAT3 after ZGGJW treatment may be responsible for the slight hepatic injury of ZGGJW based on the subtype of OA. This study provides a novel approach to better understanding of the risks and limitations when using potentially toxic Chinese patent medicine in clinical applications.
Keywords	Other systems of medicine ; RZ201-999
Subject code	610
Language	English
Publishing date	2018-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: [Epidemic situation and control strategy of malaria in Guangxi Zhuang Autonomous Region from 2011 to 2018].

Kang-Ming, Lin / Jun, Li / Shu-Jiao, Wei / Wei-Wei, Zhang / Xiang-Yang, Feng / Hui, Yan / Hai-Yan, Wei / Yi-Chao, Yang

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control

2019 Volume 31, Issue 3, Page(s) 315–318

Abstract: ... in Guangxi from 2011 to 2018.: Methods: The malaria surveillance data were collected in Guangxi Zhuang ... features of the malaria cases.: Results: A total of 2 944 malaria cases were reported in Guangxi Zhuang ...

Abstract	Objective: To analyze the epidemic situation of malaria and explore the targeted control strategy in Guangxi from 2011 to 2018. Methods: The malaria surveillance data were collected in Guangxi Zhuang Autonomous Region from 2011 to 2018, and a descriptive method was employed to analyze the epidemiological features of the malaria cases. Results: A total of 2 944 malaria cases were reported in Guangxi Zhuang Autonomous Region from 2011 to 2018, including a case with local infection (0.03%) and 2 943 imported cases (99.97%). There were 2 933 cases (99.63%) positive for Conclusions: The epidemic situation of local malaria has been effectively controlled in Guangxi; however, there is a great challenge for the management of overseas imported malaria. Strengthening the monitoring and management of migrant labors is the key to consolidate the achievements of malaria elimination.
MeSH term(s)	Adult ; China/epidemiology ; Female ; Humans ; Malaria/drug therapy ; Malaria/epidemiology ; Malaria/parasitology ; Malaria/prevention & control ; Male ; Middle Aged ; Plasmodium ; Young Adult
Language	Chinese
Publishing date	2019-09-16
Publishing country	China
Document type	Journal Article
ISSN	1005-6661
ISSN	1005-6661
DOI	10.16250/j.32.1374.2019047
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Article: [Effect of electroacupuncture combined with Zhuang-medicine-thread moxibustion on silent information regulator-1/nuclear factor κB signaling pathway in gastric antrum of diabetic gastroparesis rats].

Mai, Wei / Fan, Yu-Shan / Miao, Fu-Rui / He, Cai / Huang, Li-Lin / Zhao, Xiao-Jun / Nie, Ying-Jie / Pang, Rui-Kang

Zhen ci yan jiu = Acupuncture research

2021 Volume 46, Issue 10, Page(s) 837–844

Abstract: Objective: To observe the effect of electroacupuncture (EA) combined with Zhuang-medicine-thread ... medication, EA, Zhuang-medicine-thread moxibustion (moxibustion) and EA+moxibustion groups (: Results: (1 ... with Zhuang-medicine-thread moxibustion can effectively reduce the level of serum inflammatory factors and ...

Abstract	Objective: To observe the effect of electroacupuncture (EA) combined with Zhuang-medicine-thread moxibustion on silent information regulator-1 (SIRT1)/nuclear factor kappa B (NF-κB) signal pathway and inflammatory factor expression in gastric antrum tissue of diabetic gastroparesis (DGP) rats, so as to explore its mechanism underlying improvement of DGP. Methods: Male SD rats were randomly divided into normal, model, medication, EA, Zhuang-medicine-thread moxibustion (moxibustion) and EA+moxibustion groups ( Results: (1) Compared with the normal group, the levels of blood glucose, serum IL-6, IL-8, TNF-α, and gastric pIκ-Bα and NF-κB p65 protein and mRNA expressions were significantly increased ( Conclusion: EA combined with Zhuang-medicine-thread moxibustion can effectively reduce the level of serum inflammatory factors and regulate SIRT1/NF-κB signal pathway in DGP rats, which may contribute to its function in improving gastrointestinal movement.
MeSH term(s)	Acupuncture Points ; Animals ; Diabetes Mellitus ; Electroacupuncture ; Gastroparesis/genetics ; Gastroparesis/therapy ; Male ; Moxibustion ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Pyloric Antrum/metabolism ; Rats ; Rats, Sprague-Dawley ; Signal Transduction
Chemical Substances	NF-kappa B
Language	Chinese
Publishing date	2021-10-26
Publishing country	China
Document type	Journal Article
ZDB-ID	1283179-7
ISSN	1000-0607
ISSN	1000-0607
DOI	10.13702/j.1000-0607.200942
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Detection of Variants of B.1.617 Lineage from Five Returning Chinese Nationals at a Guangxi-Vietnam Border Port - Guangxi Zhuang Autonomous Region, China, April 2021.

Kang, Ning / Liu, Yinpin / Bi, Fuyin / Wang, Jing / Chen, Huafeng / Liang, Zhenli / Chen, Min / Wei, Guangwu / Li, Aiming / Li, Yonghong / Lu, Bao / Jiang, Zhenling / Tan, Yi / Zhong, Ge / Lin, Mei / Ju, Yu

China CDC weekly

2021 Volume 3, Issue 30, Page(s) 653–655

Language	English
Publishing date	2021-09-14
Publishing country	China
Document type	Journal Article
ISSN	2096-7071
ISSN (online)	2096-7071
DOI	10.46234/ccdcw2021.147
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: [Analysis of malaria epidemiological characteristics in Hechi City, Guangxi Zhuang Autonomous Region from 2005 to 2015].

Zhi-Qun, Meng / Jiang-Rong, Huang / Shao-Yi, Huang / Guang-Teng, Long / Kang-Ming, Lin / Ya-Ming, Huang

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control

2018 Volume 29, Issue 1, Page(s) 83–86

Abstract: Objective: To analyze the epidemiological characteristics of malaria in Hechi City, Guangxi Zhuang ...

Abstract	Objective: To analyze the epidemiological characteristics of malaria in Hechi City, Guangxi Zhuang Autonomous Region from 2005 to 2015, so as to provide the evidence for formulating and adjusting measures of malaria elimination. Methods: The data of malaria cases in 11 counties of Hechi City from 2005 to 2015 were collected and analyzed by using Micro-soft Office Excel 2003 and SPSS 17.0. Results: A total of 160 malaria cases were reported in Hechi City from 2005 to 2015, and the annual average malaria incidence was 3.6 per million. There were 10 local recurrence cases (accounting for 6.25％, 10/160) and 150 imported cases (accounting for 93.75％, 150/160). For the etiology, Conclusions: Malaria is still an important public health problem in Hechi City, and the appropriate control measures and effective tools should be strengthened for malaria elimination. The key to consolidate the achievements of malaria control is strengthening the malaria monitoring management of the floating population.
MeSH term(s)	China/epidemiology ; Cities ; Female ; Humans ; Incidence ; Malaria/epidemiology ; Malaria, Falciparum/epidemiology ; Malaria, Vivax/epidemiology ; Male
Language	Chinese
Publishing date	2018-02-22
Publishing country	China
Document type	Journal Article
ISSN	1005-6661
ISSN	1005-6661
DOI	10.16250/j.32.1374.2016063
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Article: [Malaria epidemiological situation in Wuzhou City, Guangxi Zhuang Autonomous Region from 1950 to 2015].

Qi-Ming, Li / Lian, Lian / Gui-Qiu, Pan / Chi-Sen, Li / Mu-Chang, Lin / Jia-Jie, Xu / Kang-Ming, Lin / Jun, Li / Ya-Ming, Huang

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control

2018 Volume 29, Issue 1, Page(s) 33–37

Abstract: Objective: To review and investigate the malaria control history of Wuzhou City, Guangxi Zhuang ...

Abstract	Objective: To review and investigate the malaria control history of Wuzhou City, Guangxi Zhuang Autonomous Region from 1950 to 2015, so as to provide the evidence for future malaria control and surveillance. Methods: The data of malaria control in Wuzhou City from 1950 to 2015 were collected and analyzed. Results: In 1950 decade, the malaria incidence in Wuzhou City was 1 435.55/100 000, higher than the average level in Guangxi, and the mortality of malaria was 0.95/100 000. The malaria incidence of local residents was reduced to 3.61/100 000 in 1979 and no local malaria case was found since. The imported malaria cases were found in Wuzhou City since 1980, and were more than local cases since 1981. In recent five years, 87.50% (7/8) of imported malaria cases were from south-east Asia. Conclusions: Wuzhou City has reached the national criterion of malaria elimination, but the imported malaria is the recent threat. The surveillance and control work of malaria should be strengthened.
MeSH term(s)	China/epidemiology ; Cities ; Humans ; Incidence ; Malaria/epidemiology
Language	Chinese
Publishing date	2018-02-22
Publishing country	China
Document type	Journal Article
ISSN	1005-6661
ISSN	1005-6661
DOI	10.16250/j.32.1374.2016124
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Zhuang Gu Guan Jie Wan: Reasonable Application Can Alleviate the Liver Injury for Osteoarthritis Treatment.

Liu, Bin / Fan, Danping / Sun, Wen / Zheng, Kang / Pang, Guoming / He, Xiaojuan / Xiao, Cheng / Lu, Cheng

Evidence-based complementary and alternative medicine : eCAM

2018 Volume 2018, Page(s) 6716529

Abstract: ... Chinese patent medicine, Zhuang Gu Guan Jie Wan (ZGGJW) has been brought into focus recently ...

Abstract	The potential toxicity of herbal drugs, particularly drug-induced liver injury (DILI), has received extensive attention as the use of Chinese herbal medicine has rapidly increased globally. As a classic Chinese patent medicine, Zhuang Gu Guan Jie Wan (ZGGJW) has been brought into focus recently because of its satisfactory therapeutic effects on osteoarthritis (OA) as well as its unanticipated side effects. This study aimed to decipher the puzzling phenomenon of liver injury developing in response to ZGGJW that varies by the subtype of OA. Normal, anterior cruciate ligament transaction (ACLT) and partial medial meniscectomy (MMx) induced OA and ovariectomy combined with ACLT and partial MMx induced rat models were used and treated orally with ZGGJW or distilled water for 30 days. The results from histopathology, biochemistry, and immunohistochemistry showed that ZGGJW induced liver injury, increased the level of malondialdehyde (MDA), and decreased the levels of total antioxidation capability (T-AOC), superoxide dismutase (SOD), interleukin-22 (IL-22), and signal transducer and activator of transcription factor 3 (STAT3) in the liver of normal rats, while liver injury was alleviated and showed different tendencies in the above markers for ACLT and partial MMx induction rats and ovariectomy combined with ACLT and partial MMx induction rats after ZGGJW treatment. In the OA disease states, hepatic injury induced by ZGGJW could be associated with an impairment in antioxidant capacity and the high levels of IL-22 and STAT3 after ZGGJW treatment may be responsible for the slight hepatic injury of ZGGJW based on the subtype of OA. This study provides a novel approach to better understanding of the risks and limitations when using potentially toxic Chinese patent medicine in clinical applications.
Language	English
Publishing date	2018-11-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2018/6716529
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Zs.A 5995: Show issues

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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article: [Effect of malaria surveillance and control of Guangxi Zhuang Autonomous Region in 2013].

Li, Jin-hui / Lin, Kang-ming / Wei, Shu-jiao / Wei, Hai-yan / Li, Jun / Yang, Yi-chao

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control

2015 Volume 27, Issue 1, Page(s) 41–44

Abstract: Objective: To evaluate the effect of malaria surveillance and control of Guangxi Zhuang Autonomous ...

Abstract	Objective: To evaluate the effect of malaria surveillance and control of Guangxi Zhuang Autonomous Region in 2013, and explore the suited surveillance and management of imported malaria cases, so as to provide the evidence for formulating the scientific control measures of imported malaria. Methods: The endemic data and control measures of malaria in Guangxi in 2013 were collected and analyzed statistically. Results: A total of 1 251 malaria cases were found in Guangxi in 2013, with 88.25% (1,104 cases) of falciparum malaria, 8.63% (108 cases) of vivax malaria, 0.64% (8 cases) of quartan malaria, 1.52% (19 cases) of ovale malaria, and 0.96% (12 cases) of mixed infection; 93.21% (1 166 cases) were off-farm workers; 96.56% (1,208 cases) were imported from Africa and mainly consisted of falciparum malaria cases; 3.44% (43 cases) were imported from southeast Asia and mainly consisted of vivax malaria cases. The cases of imported malaria were increasing and the infection rate in 2013 was increased by 464% compared with that in 2012. Conclusion: The imported malaria cases in Guangxi mainly come from Africa at present. Promoting the health education and professional skill of malaria control and treatment, as well as the diagnosis and treatment of the patients in early time are important measures to control the imported malaria.
MeSH term(s)	Adolescent ; Adult ; Africa ; Aged ; China/epidemiology ; Female ; Humans ; Malaria/epidemiology ; Malaria/prevention & control ; Male ; Middle Aged ; Rural Population ; Sentinel Surveillance ; Travel ; Young Adult
Language	Chinese
Publishing date	2015-02
Publishing country	China
Document type	English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1005-6661
ISSN	1005-6661
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: [Umbilical ring acupoints and its clinical application in Zhuang medicine].

Huang, Jin-Ming / Huang, Gui-Hua / Su, Qu-Zhi / Song, Ning / Li, Mei-Kang / Huang, Kai

Zhongguo zhen jiu = Chinese acupuncture & moxibustion

2013 Volume 33, Issue 6, Page(s) 561–564

Abstract: ... principle and manipulation of Umbilical Ring acupoints in Zhuang medicine are explained in this paper ... According to Zhuang medicine, umbilicus is an epitome of the body and all the zang-fu and organs in the body ...

Abstract	The theoretical basis, location, belonging of zang-fu, treatment function and indications, applying principle and manipulation of Umbilical Ring acupoints in Zhuang medicine are explained in this paper. According to Zhuang medicine, umbilicus is an epitome of the body and all the zang-fu and organs in the body have corresponding epitomes like a fetus in front-standing position. The umbilicus is not only a micro-diagnosis system, but also a window for illness treatment that could be divided into superficial, middle and deep layer to respectively communicate different zang-fu and organs. The umbilical inner ring and outer ring are collectively called Umbilical Ring acupoints, they could dredge paths, regulate the balance of qi and blood to regulate qi, expel poison, tonify deficiency and remove stasis to treat many types of diseases in the whole body.
MeSH term(s)	Acupuncture Points ; Acupuncture Therapy ; Humans ; Medicine, Chinese Traditional ; Umbilicus/anatomy & histology
Language	Chinese
Publishing date	2013-06
Publishing country	China
Document type	English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	0255-2930
ISSN	0255-2930
Database	MEDical Literature Analysis and Retrieval System OnLINE

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