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Article ; Online: Distal-triangular flap design for impacted mandibular third molars: a randomized controlled trial.

Liu, Ji-Yuan / Liu, Chang / Pan, Jian / Qu, Tao / Hua, Cheng-Ge

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

2021 Volume 39, Issue 5, Page(s) 598–604

Abstract: Objectives: This prospective study was performed to evaluate whether the distal-triangular flap was a practical alternative surgical approach for extracting mandibular third molars.: Methods: Sixty participants with impacted mandibular third molars ... ...

Abstract	Objectives: This prospective study was performed to evaluate whether the distal-triangular flap was a practical alternative surgical approach for extracting mandibular third molars. Methods: Sixty participants with impacted mandibular third molars were randomly divided into three groups: group A, distal-triangular flap; group B, Szmyd flap; and group C, envelope flap. The impacted third molars were extracted by the corresponding flapping method. During a three-month follow-up observation after the extraction, the postoperative pain, swelling, mouth opening, and periodontal status were recorded and analyzed by ANOVA and chi-square tests. Results: The 60 participants had successful extraction and 3-month follow-up observation. No participant suffered from postoperative infections, lower lip disorder, or tongue sensory disorders. No statistical differences were found in the postoperative symptoms and signs of the three flap designs, such as postoperative pain, swelling, mouth opening, and periodontal status ( Conclusions: The distal-triangular flap was as safe and reliable as the Szmyd and envelope flaps but more advantageous because of its convenient operative field exposure and low requirement for the patient's mouth opening. Thus, the distal-triangular flap is one of the alternative flap options for extracting impacted mandibular third molars.
MeSH term(s)	Humans ; Mandible/surgery ; Molar, Third/surgery ; Prospective Studies ; Tooth Extraction ; Tooth, Impacted/surgery
Language	Chinese
Publishing date	2021-10-12
Publishing country	China
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	1202342-5
ISSN	2618-0456 ; 1000-1182
ISSN (online)	2618-0456
ISSN	1000-1182
DOI	10.7518/hxkq.2021.05.016
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Article ; Online: [Strategy of dental clinics to cope with the epidemic period of infectious diseases based on the experience of corona virus disease outbreak].

Hua, Cheng-Ge / Liu, Zhi-Qing / Wang, Qing / Yang, Zheng / Xu, Qing-Hong / Zhang, Jing

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

2020 Volume 38, Issue 2, Page(s) 117–121

Abstract: The outbreak of corona virus disease (COVID-19) has raised concerns among dentists to develop strategies to prevent infection of dental equipment, materials, and patients during an epidemic period. Strategies following the National Laws and Standards of ... ...

Abstract	The outbreak of corona virus disease (COVID-19) has raised concerns among dentists to develop strategies to prevent infection of dental equipment, materials, and patients during an epidemic period. Strategies following the National Laws and Standards of China and local standards of several provinces for controlling cross-infection and instituting protective measures for medical staff in dental clinics during an epidemic period are discussed. A proposal is put forth for dental clinics that will face similar situations in the future. Further research is warranted to address potential problems that will be encountered under such dire circumstances.
MeSH term(s)	Betacoronavirus ; COVID-19 ; China ; Coronavirus ; Coronavirus Infections ; Dental Clinics ; Dental Equipment ; Disease Outbreaks ; Humans ; Infection Control ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	Chinese
Publishing date	2020-04-21
Publishing country	China
Document type	Journal Article
ZDB-ID	1202342-5
ISSN	2618-0456 ; 1000-1182
ISSN (online)	2618-0456
ISSN	1000-1182
DOI	10.7518/hxkq.2020.02.001
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Article ; Online: [Research progress on the modification of guided bone regeneration membranes].

Cao, Yu-Bin / Liu, Chang / Pan, Wei-Lin / Tu, Yuan / Li, Chun-Jie / Hua, Cheng-Ge

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

2019 Volume 37, Issue 3, Page(s) 325–329

Abstract: Guided bone regeneration (GBR) is an important technique to solve bone defect problems. In this technique, GBR barrier membranes play an irreplaceable role. GBR membranes can act as a barrier protecting fibroblasts from bone defects and promote ... ...

Abstract	Guided bone regeneration (GBR) is an important technique to solve bone defect problems. In this technique, GBR barrier membranes play an irreplaceable role. GBR membranes can act as a barrier protecting fibroblasts from bone defects and promote osteoblast adhesion and proliferation, leading to bone regeneration. GBR barrier membranes should be enhanced because of the disadvantages of collagen membranes, which are extensively applied to the field of GBR. Therefore, various efforts have been devoted to modifying the antibacterial and osteogenic properties of GBR barrier membranes and developing novel materials. This article reviews the research advancements on the modification of GBR barrier membranes and discover future directions for the development of GBR barrier membranes to provide a reference for bone tissue engi-neering and repair.
MeSH term(s)	Bone Regeneration ; Collagen ; Membranes, Artificial ; Osteoblasts ; Osteogenesis
Chemical Substances	Membranes, Artificial ; Collagen (9007-34-5)
Language	Chinese
Publishing date	2019-06-20
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	1202342-5
ISSN	2618-0456 ; 1000-1182
ISSN (online)	2618-0456
ISSN	1000-1182
DOI	10.7518/hxkq.2019.03.019
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Article ; Online: [Prognosis of teeth with external root resorption caused by adjacent impacted teeth].

Lai, Ying / Pan, Wei-Lin / Liu, Chang / Huang, Jing-Yuan / Hua, Cheng-Ge

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

2019 Volume 37, Issue 3, Page(s) 280–284

Abstract: Objective: This study aimed to investigate the prognosis of permanent teeth with external root resorption (ERR) caused by adjacent impacted teeth.: Methods: A total of 75 ERR teeth (permanent teeth) caused by adjacent impacted teeth of 63 patients ... ...

Abstract	Objective: This study aimed to investigate the prognosis of permanent teeth with external root resorption (ERR) caused by adjacent impacted teeth. Methods: A total of 75 ERR teeth (permanent teeth) caused by adjacent impacted teeth of 63 patients were included. The prognosis of ERR teeth was analyzed followed by minimally invasive extraction of the adjacent impacted teeth. The time of follow-up was six months. The relationship between prognosis of ERR teeth and patients' age, gender, root number, type of root resorption and degree of root resorption were analyzed. Results: In the 75 ERR teeth, 67 teeth (89.3%) did not show pulpitis symptoms. The clinical outcome was found to be related with age (r=0.330, P<0.05), whereas no relationships with gender, root number, as well as type and degree of root resorption were observed (P>0.05). Pulpitis symptom was not found in ERR teeth of patients under 30 years old. Conclusions: For ERR teeth caused by adjacent impacted teeth, keeping the pulp vital after surgical removal of impacted teeth is highly probable. Post-operative follow-up instead of preventive root canal therapy of ERR teeth is recommended.
MeSH term(s)	Adult ; Humans ; Prognosis ; Pulpitis ; Root Canal Therapy ; Root Resorption ; Tooth, Impacted
Language	Chinese
Publishing date	2019-06-20
Publishing country	China
Document type	Journal Article
ZDB-ID	1202342-5
ISSN	2618-0456 ; 1000-1182
ISSN (online)	2618-0456
ISSN	1000-1182
DOI	10.7518/hxkq.2019.03.010
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Article ; Online: Development and validation of the screening tool for age-related hearing loss in the community based on the information platform.

Ge, Jianli / Yan, Yunyun / Zhu, Yinqian / Cheng, Xin / Li, Huazhang / Sun, Xiaoming / Jiang, Hua

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

2024 Volume 281, Issue 6, Page(s) 2893–2903

Abstract: Introduction: Currently, age-related hearing loss has become prevalent, awareness and screening rates remain dismally low. Duing to several barriers, as time, personnel training and equipment costs, available hearing screening tools do not adequately ... ...

Abstract	Introduction: Currently, age-related hearing loss has become prevalent, awareness and screening rates remain dismally low. Duing to several barriers, as time, personnel training and equipment costs, available hearing screening tools do not adequately meet the need for large-scale hearing detection in community-dwelling older adults. Therefore, an accurate, convenient, and inexpensive hearing screening tool is needed to detect hearing loss, intervene early and reduce the negative consequences and burden of untreated hearing loss on individuals, families and society. Objectives: The study harnessed "medical big data" and "intelligent medical management" to develop a multi-dimensional screening tool of age-related hearing loss based on WeChat platform. Methods: The assessment of risk factors was carried out by cross-sectional survey, logistic regression model and receiver operating characteristic (ROC) curve analysis. Combining risk factor assessment, Hearing handicap inventory for the elderly screening version and analog audiometry, the screening software was been developed by JavaScript language and been evaluated and verified. Results: A total of 401 older adults were included in the cross-sectional study. Logistic regression model (univariate, multivariate) and reference to literature mention rate of risk factors, 18 variables (male, overweight/obesity, living alone, widowed/divorced, history of noise, family history of deafness, non-light diet, no exercising habit, smoking, drinking, headset wearer habit, hypertension, diabetes, hyperlipidemia, cardiovascular and cerebrovascular diseases, hyperuricemia, hypothyroidism, history of ototoxic drug use) were defined as risk factors. The area under the ROC curve (AUC) of the cumulative score of risk factors for early prediction of age-related hearing loss was 0.777 [95% CI (0.721, 0.833)]. The cumulative score threshold of risk factors was defined as 4, to classify the older adults into low-risk (< 4) and high-risk (≥ 4) hearing loss groups. The sensitivity, specificity, positive predictive value, and negative predictive value of the screen tool were 100%, 65.5%, 71.8%, and 100.0%, respectively. The Kappa index was 0.6. Conclusions: The screening software enabled the closed loop management of real-time data transmission, early warning, management, whole process supervision of the hearing loss and improve self-health belief in it. The software has huge prospects for application as a screening approach for age-related hearing loss.
MeSH term(s)	Humans ; Male ; Female ; Aged ; Cross-Sectional Studies ; Mass Screening/methods ; Risk Factors ; Middle Aged ; Hearing Loss/diagnosis ; Hearing Loss/epidemiology ; ROC Curve ; Aged, 80 and over ; Presbycusis/diagnosis ; Presbycusis/epidemiology ; Risk Assessment/methods ; Logistic Models ; Independent Living
Language	English
Publishing date	2024-01-11
Publishing country	Germany
Document type	Journal Article ; Validation Study
ZDB-ID	1017359-6
ISSN	1434-4726 ; 0937-4477
ISSN (online)	1434-4726
ISSN	0937-4477
DOI	10.1007/s00405-023-08389-9
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Article ; Online: [Clinical study of age-related sensory innervation of the anterior hard palate].

Li, Xiu-Fen / Liu, Chang / Liu, Ji-Yuan / Qu, Tao / Pan, Wei-Lin / Pan, Jian / Hua, Cheng-Ge

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

2020 Volume 39, Issue 2, Page(s) 170–174

Abstract: Objectives: The present study aimed to explore the innervation of the anterior hard palatine and its relationship with individual development stage. Specifically, the effects of anesthesia on patients of different ages were observed, and ... ...

Abstract	Objectives: The present study aimed to explore the innervation of the anterior hard palatine and its relationship with individual development stage. Specifically, the effects of anesthesia on patients of different ages were observed, and neurodevelopment in the maxillofacial region was invesitgated. References that are helpful in selecting local anesthesia were provided. Methods: A total of 182 patients with mixed dentition were randomly divided into the nasopalatine nerve block and greater palatine nerve block groups. Then, 219 patients with permanent dentition were divided into an adolescent group (13-18 years old) and adult group (over 19 years old), all of whom underwent bilateral greater palatine nerve block. Palatal mucosal pain sensation was tested pre- and post-anesthesia with Von Frey hairs. Results: Among the children with mixed dentition, bilateral greater palatine nerve block tended to result in better anesthetic effects than nasopalatine nerve block ( Conclusions: The sensation of the anterior hard palatine seems mainly dominated by the greater palatine nerve until mixed dentition and gradually shifted to the nasopalatine nerve in conjunction with maxillary development and tooth replacement. Hence, the innervation of the anterior hard palatine induce a secondary development during the development of the maxilla.
MeSH term(s)	Adolescent ; Adult ; Child ; Dentition, Mixed ; Humans ; Maxilla ; Maxillary Nerve ; Nerve Block ; Palate ; Palate, Hard ; Young Adult
Language	Chinese
Publishing date	2020-04-21
Publishing country	China
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	1202342-5
ISSN	2618-0456 ; 1000-1182
ISSN (online)	2618-0456
ISSN	1000-1182
DOI	10.7518/hxkq.2021.02.007
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Article: [Effectiveness of adjunctive photodynamic therapy in the treatment of stage Ⅲ and Ⅳ periodontitis].

Fan, Ya-Dan / Shu, Rong / Cheng, Lan / Ge, Lin-Hua

Shanghai kou qiang yi xue = Shanghai journal of stomatology

2023 Volume 31, Issue 5, Page(s) 501–506

Abstract: Purpose: To explore the clinical effect of subgingival scaling and root planning (SRP) with adjunctive photodynamic therapy (PDT) in the treatment of stage Ⅲ and Ⅳ periodontitis.: Methods: According to 2018 Classification of Periodontitis, patients ... ...

Abstract	Purpose: To explore the clinical effect of subgingival scaling and root planning (SRP) with adjunctive photodynamic therapy (PDT) in the treatment of stage Ⅲ and Ⅳ periodontitis. Methods: According to 2018 Classification of Periodontitis, patients diagnosed as stage Ⅲ and Ⅳ periodontitis were recruited. One week after supragingival scaling, probing depth (PD), bleeding on probing (BOP) and gingival index (GI) were recorded as the baseline. All patients were divided into 3 groups, SRP group received whole mouth SRP treatment; PDT1 group: PDT at all sites with PD≥5 mm immediately after SRP; PDT2 group received another PDT at the test sites 6 weeks after full mouth SRP+PDT. PD, GI and the positive rates of BOP were compared 3 months and 6 months after treatment. SPSS 22.0 software package was used for data analysis. Results: Thirty patients and 1 289 test sites were included in this trial. There were 10 patients in group SRP, PDT1 and PDT2, and the number of tests sites were 476, 36.9%, 384, 29.8% and 429 33.3%, respectively. The PD, GI and the positive rates of BOP in the three groups were reduced at 3-months and 6-months of follow-up (P<0.05), there was no significant difference between 3-months and 6-months of follow-up. At the site of PD≥5 mm, group PDT1 and PDT2 could significantly reduce GI and the positive rates of BOP at the test sites(P<0.05). When PD≥7 mm, significant PD reduction was observed in group PDT2(P<0.05). Conclusions: In the treatment of stage Ⅲ and Ⅳ periodontitis, PDT assisted with SRP therapy can achieve better clinical effect than SRP alone.
MeSH term(s)	Humans ; Chronic Periodontitis/therapy ; Dental Care ; Dental Scaling ; Periodontitis/drug therapy ; Photochemotherapy/adverse effects ; Root Planing
Language	Chinese
Publishing date	2023-02-08
Publishing country	China
Document type	Clinical Trial ; English Abstract ; Journal Article
ZDB-ID	2269714-7
ISSN	1006-7248
ISSN	1006-7248
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Zs.A 6471: Show issues

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Article: [Strategy of dental clinics to cope with the epidemic period of infectious diseases based on the experience of corona virus disease outbreak]

Hua, Cheng-Ge / Liu, Zhi-Qing / Wang, Qing / Yang, Zheng / Xu, Qing-Hong / Zhang, Jing

Hua Xi Kou Qiang Yi Xue Za Zhi

Abstract	The outbreak of corona virus disease (COVID-19) has raised concerns among dentists to develop strategies to prevent infection of dental equipment, materials, and patients during an epidemic period. Strategies following the National Laws and Standards of China and local standards of several provinces for controlling cross-infection and instituting protective measures for medical staff in dental clinics during an epidemic period are discussed. A proposal is put forth for dental clinics that will face similar situations in the future. Further research is warranted to address potential problems that will be encountered under such dire circumstances.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #154376
Database	COVID19

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Article ; Online: [Relationship between initial archwire materials and pain at the initial stage of orthodontic treatment: a systematic review and network Meta-analysis].

Liu, Chang / Wang, Yan / Pan, Wei-Lin / Yu, Chang-Hao / Huang, Jing-Yuan / Hua, Cheng-Ge

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

2018 Volume 36, Issue 3, Page(s) 296–300

Abstract: Objective: This review aims to assess the relationship between initial archwire materials and pain at the initial stage of orthodontic treatment.: Methods: On October 1, 2017, seven databases were searched electronically for studies oninitial ... ...

Abstract	Objective: This review aims to assess the relationship between initial archwire materials and pain at the initial stage of orthodontic treatment. Methods: On October 1, 2017, seven databases were searched electronically for studies oninitial archwire materials and pain at the initial stage of orthodontic treatment. Quality assessment was performed with bias risk assessment tools suggested by Cochrane's handbook. Data extraction of included studies was also carried out. Network Meta- analysis was conducted using R 3.4.2 (with JAGS 4.3.0), GeMTC 0.14.3, and STATA 11.0. Results: Five studies with 330 participants were included, comparing four different materials: multi-stranded stainless steel, conventional nickel-titanium, super-elastic nickel-titanium, and thermal heat-activated nickel-titanium. Two studies were at low risk of bias, one was at high risk of bias, and the remaining two were at unclear risk of bias. Network Meta-analysis results showed no statistical differences of pain among the four initial archwire materials at day 1 and day 7. However, the most painless material was most likely to be thermal heat-activated nickel-titanium on rank probability. Conclusions: On statistical probability, thermal heat-activated nickel-titanium initial arch wires is most likely to cause the least pain at the initial stage of orthodontic treatment, compared with other materials.
MeSH term(s)	Dental Alloys ; Humans ; Materials Testing ; Network Meta-Analysis ; Nickel ; Orthodontic Appliance Design ; Orthodontic Brackets ; Orthodontic Wires/adverse effects ; Pain ; Stainless Steel ; Surface Properties ; Titanium
Chemical Substances	Dental Alloys ; Stainless Steel (12597-68-1) ; Nickel (7OV03QG267) ; Titanium (D1JT611TNE)
Language	Chinese
Publishing date	2018-07-07
Publishing country	China
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	1202342-5
ISSN	2618-0456 ; 1000-1182
ISSN (online)	2618-0456
ISSN	1000-1182
DOI	10.7518/hxkq.2018.03.013
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Article: Mycobacterium tuberculosis inhibits METTL14-mediated m

Ma, Mingtong / Duan, Yongjia / Peng, Cheng / Wu, You / Zhang, Xinning / Chang, Boran / Wang, Fei / Yang, Hua / Zheng, Ruijuan / Cheng, Hongyu / Cheng, Yuanna / He, Yifan / Huang, Jingping / Lei, Jinming / Ma, Hanyu / Li, Liru / Wang, Jie / Huang, Xiaochen / Tang, Fen /

Liu, Jun / Li, Jinsong / Ying, Ruoyan / Wang, Peng / Sha, Wei / Gao, Yawei / Wang, Lin / Ge, Baoxue

Cell discovery

2024 Volume 10, Issue 1, Page(s) 36

Abstract: ... Internal ... ...

Abstract	Internal N
Language	English
Publishing date	2024-03-29
Publishing country	England
Document type	Journal Article
ISSN	2056-5968
ISSN	2056-5968
DOI	10.1038/s41421-024-00653-4
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