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  1. Article ; Online: Recyclable Curcumin-Based Bioepoxy Resin with On-Demand Chemical Cleavability.

    Jeong, Jisu / Ju, Yeonha / Hong, Younggi / Oh, Dongki / Goh, Munju

    ACS omega

    2024  Volume 9, Issue 8, Page(s) 9585–9592

    Abstract: We synthesized a novel curcumin-based bioepoxy resin by introducing epichlorohydrin (ECH) into the hydroxyl groups of curcumin and analyzed it using Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR). The epoxy equivalent ...

    Abstract We synthesized a novel curcumin-based bioepoxy resin by introducing epichlorohydrin (ECH) into the hydroxyl groups of curcumin and analyzed it using Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance (NMR). The epoxy equivalent weight (EEW) was determined based on a reaction with sodium hydroxide (NaOH) through titration, and the actual curing process was conducted after exploring the optimal conditions using an amine-based curing agent through dynamic scanning in differential scanning calorimetry (DSC) and isotherm analysis. The cured epoxy resin had a tensile strength, Young's modulus, and glass transition temperature (
    Language English
    Publishing date 2024-02-17
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c09464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The effect of Tai Chi exercise intervention on sleep quality in community residing older adults: a systematic review and meta-analysis.

    Lyu, Linyu / Li, Yuelin / Fan, Xing / Seo, Jisu / Eunna, Oh

    European geriatric medicine

    2024  Volume 15, Issue 2, Page(s) 381–396

    Abstract: Purpose: While clinical research has shown that Tai Chi exercise may improve the sleep quality of older adults, there is a lack of robust evidence-based verification. Therefore, this study conducted a systematic review of published research on the ... ...

    Abstract Purpose: While clinical research has shown that Tai Chi exercise may improve the sleep quality of older adults, there is a lack of robust evidence-based verification. Therefore, this study conducted a systematic review of published research on the effect of Tai Chi exercise on the sleep quality of community-dwelling older adults, aiming to provide solid evidence-based medicine to enhance their sleep quality.
    Methods: A systematic search was conducted on PubMed, Embase, Cochrane Library, Web of Science, CNKI, WanFang, VIP, and SinoMed databases from their inception to December 9, 2022. The Cochrane risk of bias assessment tool 2.0 was used to assess the risk of bias in the included studies.
    Results: This systematic review included 12 original articles, involving a total of 1,058 community-dwelling older adults, with 553 in the Tai Chi group and 505 in the control group. The meta-analysis results revealed a significant improvement in the sleep quality of community-dwelling older adults who practiced Tai Chi compared to the control group [WMD =  - 1.96 (95% CI: - 3.02 to - 0.90, z = 3.62, P < 0.001)]. Subgroup analysis showed that Tai Chi had significantly beneficial effects regardless of age, country/region, intervention time, and Tai Chi type.
    Conclusions: Tai Chi exercise can serve as an effective non-medication approach for addressing sleep problems in this demographic. Among the various types of Tai Chi exercises, the 24-form Tai Chi exercise emerges as a preferred option. Moreover, Tai Chi exercise proves to be an excellent choice for older people in their later years, promoting their overall well-being and health.
    MeSH term(s) Humans ; Aged ; Tai Ji ; Sleep Quality ; Exercise ; Exercise Therapy
    Language English
    Publishing date 2024-01-16
    Publishing country Switzerland
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2556794-9
    ISSN 1878-7657 ; 1878-7649
    ISSN (online) 1878-7657
    ISSN 1878-7649
    DOI 10.1007/s41999-023-00923-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correction: Using Wake-Up Tasks for Morning Behavior Change: Development and Usability Study.

    Oh, Kyue Taek / Ko, Jisu / Shin, Jaemyung / Ko, Minsam

    JMIR formative research

    2022  Volume 6, Issue 10, Page(s) e42926

    Abstract: This corrects the article DOI: 10.2196/39497.]. ...

    Abstract [This corrects the article DOI: 10.2196/39497.].
    Language English
    Publishing date 2022-10-03
    Publishing country Canada
    Document type Published Erratum
    ISSN 2561-326X
    ISSN (online) 2561-326X
    DOI 10.2196/42926
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Correlation between Carboxyhemoglobin Levels Measured by Blood Gas Analysis and by Multiwave Pulse Oximetry.

    Yu, Jisu / Lee, Juncheol / Cho, Yongil / Oh, Jaehoon / Kang, Hyunggoo / Lim, Tae Ho / Ko, Byuk Sung

    Journal of personalized medicine

    2024  Volume 14, Issue 2

    Abstract: Carbon monoxide (CO) poisoning is difficult to diagnose owing to its nonspecific symptoms. Multiwave pulse oximetry can be used to quickly screen patients for CO poisoning. However, few studies have analyzed patients with CO poisoning who presented to ... ...

    Abstract Carbon monoxide (CO) poisoning is difficult to diagnose owing to its nonspecific symptoms. Multiwave pulse oximetry can be used to quickly screen patients for CO poisoning. However, few studies have analyzed patients with CO poisoning who presented to the emergency department (ED). The primary aim of our study was to determine the correlation between COHb levels measured in blood gas analysis and COHb levels measured in multiwave pulse oximetry. Secondary aims were the sensitivity and specificity of the COHb level cutoff value using multiwave pulse oximetry to predict a 25% COHb level in blood gas analysis. This single-center retrospective observational study included patients with CO poisoning who visited the ED of a university-affiliated hospital in Seoul, Korea between July 2021 and June 2023. COHb poisoning was determined using blood gas analysis and multiwave pulse oximetry. The correlation of COHb levels between the two tests was evaluated using correlation analysis. The area under the receiver operating characteristic curve (AUC) of multiwave pulse oximetry was calculated to predict COHb levels from the blood gas analysis. The optimal cutoff values, sensitivity, and specificity of COHb were determined. A total of 224 patients who had COHb levels measured using both multiwave pulse oximetry and blood gas analysis were included in the analysis. In the correlation analysis, COHb showed a high positive correlation with COHb measured using blood gas analysis (Spearman correlation coefficient = 0.86,
    Language English
    Publishing date 2024-01-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm14020168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Intramedullary Stabilization Technique Using Headless Compression Screws for Distal Ulnar Fractures.

    Oh, Jin Rok / Park, Jisu

    Clinics in orthopedic surgery

    2020  Volume 12, Issue 1, Page(s) 130–134

    Abstract: Distal ulnar fractures are commonly accompanied by distal radial fractures, and several treatment options such as plate osteosynthesis and pinning with Kirschner's wires are used. In this study, we present a technique using headless compression screws to ...

    Abstract Distal ulnar fractures are commonly accompanied by distal radial fractures, and several treatment options such as plate osteosynthesis and pinning with Kirschner's wires are used. In this study, we present a technique using headless compression screws to achieve bony union of distal ulnar fractures. From November 2016 to November 2018, we treated 11 patients with distal ulnar fractures combined with distal radial fractures with headless compression screws (DePuy Synthes). Patients were instructed to maintain a short-arm splint for less than two weeks after the treatment. The mean time to bony union was 6.5 weeks, mean Quick Disabilities of the Arm, Shoulder, and Hand score was 14.6 points, and mean visual analog scale score was 1.09 points. Full range of motion was possible in all directions after surgery and no specific complications were observed. The suggested technique allows minimal incision and minimally invasive intramedullary fixation and can promote bony union in a simple way without specific complications.
    MeSH term(s) Aged, 80 and over ; Bone Screws ; Female ; Fracture Fixation, Intramedullary/instrumentation ; Fracture Fixation, Intramedullary/methods ; Humans ; Middle Aged ; Radius Fractures/surgery ; Ulna Fractures/surgery
    Language English
    Publishing date 2020-02-13
    Publishing country Korea (South)
    Document type Case Reports ; Journal Article
    ZDB-ID 2485469-4
    ISSN 2005-4408 ; 2005-291X
    ISSN (online) 2005-4408
    ISSN 2005-291X
    DOI 10.4055/cios.2020.12.1.130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Combination of [

    Kim, Jisu / Lee, Seunghwan / Kim, Dongwoo / Kim, Hyun Jeong / Oh, Kyeong Taek / Kim, Sun Jung / Choi, Young Deuk / Giesel, Frederik L / Kopka, Klaus / Hoepping, Alexander / Lee, Misu / Yun, Mijin

    European journal of nuclear medicine and molecular imaging

    2024  Volume 51, Issue 6, Page(s) 1763–1772

    Abstract: Purpose: [: Method: This prospective study included 42 index tumours (27 acinar and 15 ductal-dominant) in 42 patients who underwent [: Results: All 42 index tumours were detected on [: Conclusions: [ ...

    Abstract Purpose: [
    Method: This prospective study included 42 index tumours (27 acinar and 15 ductal-dominant) in 42 patients who underwent [
    Results: All 42 index tumours were detected on [
    Conclusions: [
    MeSH term(s) Humans ; Male ; Positron Emission Tomography Computed Tomography ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/surgery ; Prostatic Neoplasms/pathology ; Aged ; Middle Aged ; Fluorodeoxyglucose F18 ; Neoplasm Staging ; Oligopeptides/chemistry ; Niacinamide/analogs & derivatives ; Prospective Studies ; Radiopharmaceuticals ; Postoperative Period
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; PSMA-1007 ; Oligopeptides ; Niacinamide (25X51I8RD4) ; Radiopharmaceuticals
    Language English
    Publishing date 2024-01-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 8236-3
    ISSN 1619-7089 ; 0340-6997 ; 1619-7070
    ISSN (online) 1619-7089
    ISSN 0340-6997 ; 1619-7070
    DOI 10.1007/s00259-023-06585-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Using Wake-Up Tasks for Morning Behavior Change: Development and Usability Study.

    Oh, Kyue Taek / Ko, Jisu / Shin, Jaemyung / Ko, Minsam

    JMIR formative research

    2022  Volume 6, Issue 9, Page(s) e39497

    Abstract: Background: Early morning behaviors between waking up and beginning daily work can develop into productive habits. However, sleep inertia limits the level of human ability immediately after waking, lowering a person's motivation and available time for ... ...

    Abstract Background: Early morning behaviors between waking up and beginning daily work can develop into productive habits. However, sleep inertia limits the level of human ability immediately after waking, lowering a person's motivation and available time for productive morning behavior.
    Objective: This study explores a design for morning behavior change using a wake-up task, a simple assignment the user needs to finish before alarm dismissal. Specifically, we set two research objectives: (1) exploring key factors that relate to morning behavior performance, including the use of wake-up tasks in an alarm app and (2) understanding the general practice of affecting morning behavior change by implementing wake-up tasks.
    Methods: We designed and implemented an apparatus that provides wake-up task alarms and facilities for squat exercises. We recruited 36 participants to perform squat exercises in the early morning using the wake-up tasks for 2 weeks. First, we conducted a generalized estimating equation (GEE) analysis for the first research objective. Next, we conducted a thematic analysis of the postsurvey answers to identify key themes about morning behavior change with the wake-up tasks for the second objective.
    Results: The use of wake-up tasks was significantly associated with both the completion of the target behavior (math task: P=.005; picture task: P<.001) and the elapsed time (picture task: P=.08); the time to alarm dismissal was significantly related to the elapsed time to completion (P<.001). Moreover, the theory of planned behavior (TPB) variables, common factors for behavior change, were significant, but their magnitudes and directions differed slightly from the other domains. Furthermore, the survey results reveal how the participants used the wake-up tasks and why they were effective for morning behavior performance.
    Conclusions: The results reveal the effectiveness of wake-up tasks in accomplishing the target morning behavior and address key factors for morning behavior change, such as (1) waking up on time, (2) escaping from sleep inertia, and (3) quickly starting the desired target behavior.
    Language English
    Publishing date 2022-09-21
    Publishing country Canada
    Document type Journal Article
    ISSN 2561-326X
    ISSN (online) 2561-326X
    DOI 10.2196/39497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: Practical and Matching Gradient Variance Bounds for Black-Box Variational Bayesian Inference

    Kim, Kyurae / Wu, Kaiwen / Oh, Jisu / Gardner, Jacob R.

    2023  

    Abstract: Understanding the gradient variance of black-box variational inference (BBVI) is a crucial step for establishing its convergence and developing algorithmic improvements. However, existing studies have yet to show that the gradient variance of BBVI ... ...

    Abstract Understanding the gradient variance of black-box variational inference (BBVI) is a crucial step for establishing its convergence and developing algorithmic improvements. However, existing studies have yet to show that the gradient variance of BBVI satisfies the conditions used to study the convergence of stochastic gradient descent (SGD), the workhorse of BBVI. In this work, we show that BBVI satisfies a matching bound corresponding to the $ABC$ condition used in the SGD literature when applied to smooth and quadratically-growing log-likelihoods. Our results generalize to nonlinear covariance parameterizations widely used in the practice of BBVI. Furthermore, we show that the variance of the mean-field parameterization has provably superior dimensional dependence.

    Comment: Accepted to ICML'23 for live oral presentation
    Keywords Computer Science - Machine Learning ; Mathematics - Optimization and Control ; Statistics - Computation ; Statistics - Machine Learning
    Subject code 510
    Publishing date 2023-03-18
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: miR-4284 Functions as a Tumor Suppressor in Renal Cell Carcinoma Cells by Targeting Glutamate Decarboxylase 1.

    Choi, Sujin / Kim, Kyeongmi / Yeo, Hyunjeong / Lee, Gyurim / Kim, Isaac / Oh, Jisu / An, Hyun-Ju / Lee, Soonchul

    Cancers

    2023  Volume 15, Issue 15

    Abstract: MicroRNAs (miRNAs) play a crucial role as oncogenic or tumor suppressors in the pathogenesis and progression of tumors. However, few studies have investigated the exact role of miR-4284 in renal cell carcinoma (RCC). We aimed to investigate the role of ... ...

    Abstract MicroRNAs (miRNAs) play a crucial role as oncogenic or tumor suppressors in the pathogenesis and progression of tumors. However, few studies have investigated the exact role of miR-4284 in renal cell carcinoma (RCC). We aimed to investigate the role of miR-4284 as a tumor suppressor in renal cancer cell lines. A498 and Caki-1 were transfected with miR-4284. The Cell Counting Kit-8, colony formation, apoptosis assays, and quantitative reverse transcription-polymerase chain reaction were used to evaluate tumor growth-inhibiting functions. The wound-healing, transwell, and sphere-formation assays were conducted to investigate tumorigenic characteristics. The potential target genes of miR-4284 were predicted and experimentally verified. A xenograft experiment was performed to estimate the tumor-growth-suppressive function of miR-4284. miR-4284 overexpression suppressed proliferation, induced apoptosis, and suppressed tumorigenic features of renal cancer cells. Glutamate decarboxylase 1 (GAD1) was directly targeted by miR-4284. A xenograft mouse model injected with Caki-1 cells transfected with miR-4284 showed significantly decreased tumor growth rate and volume. miR-4284 affected tumor growth, metastasis, and apoptosis of renal cancer cells in vitro and in vivo. These findings highlight the potential of miR-4284 as a target for anticancer miRNA therapeutics in RCC.
    Language English
    Publishing date 2023-07-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15153888
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: High-Volume Hospital Had Lower Mortality of Severe Intracerebral Hemorrhage Patients.

    Park, Sang-Won / Han, James Jisu / Heo, Nam Hun / Lee, Eun Chae / Lee, Dong-Hun / Lee, Ji Young / Lee, Boung Chul / Lim, Young Wha / Kim, Gui Ok / Oh, Jae Sang

    Journal of Korean Neurosurgical Society

    2024  

    Abstract: Objective: Intracerebral hemorrhage (ICH) accompanies higher mortality rates than other type of stroke. This study aimed to investigate the association between hospital volume and mortality for cases of ICH.: Methods: We used nationwide data from ... ...

    Abstract Objective: Intracerebral hemorrhage (ICH) accompanies higher mortality rates than other type of stroke. This study aimed to investigate the association between hospital volume and mortality for cases of ICH.
    Methods: We used nationwide data from 2013 to 2018 to compare high-volume hospitals (≥32 admissions/year) and low-volume hospitals (<32 admissions/year). We tracked patients' survival at 3-month, 1-year, 2-year, and 4-year endpoints. The survival of ICH patients was analyzed at 3-month, 1-year, 2-year, and 4-year endpoints using Kaplan-Meier survival analysis. Multivariable logistic regression analysis and Cox regression analysis were performed to determine predictive factors of poor outcomes at discharge and death.
    Results: Among 9,086 ICH patients who admitted to hospital during 18-month period, 6,756 (74.4%) and 2,330 (25.6%) patients were admitted to high-volume and low-volume hospitals. The mortality of total ICH patients was 18.25%, 23.87%, 27.88%, and 35.74% at the 3-month, 1-year, 2-year, and 4-year, respectively. In multivariate logistic analysis, high-volume hospitals had lower poor functional outcome at discharge than low-volume hospitals (odds ratio, 0.80; 95% confidence interval, 0.72-0.91; p < 0.001). In the Cox analysis, high-volume hospitals had significantly lower 3-month, 1-year, 2-year, and 4-year mortality than low-volume hospitals (p < 0.05).
    Conclusion: The poor outcome at discharge, short- and long-term mortality in ICH patients differed according to hospital volume. High-volume hospitals showed lower rates of mortality for ICH patients, particularly those with severe clinical status.
    Language English
    Publishing date 2024-03-04
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2253817-3
    ISSN 1598-7876 ; 2005-3711 ; 1225-8245
    ISSN (online) 1598-7876
    ISSN 2005-3711 ; 1225-8245
    DOI 10.3340/jkns.2023.0205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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