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  1. Book: Gout and calcium crystal related arthropathies

    Neogi, Tuhina

    (Rheumatic disease clinics of North America ; 40,2)

    2014  

    Author's details ed. Ruhina Neogi
    Series title Rheumatic disease clinics of North America ; 40,2
    Collection
    Language English
    Size XVI S., S. 156 - 399 : Ill., graph. Darst.
    Publisher Elsevier
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT018271628
    ISBN 978-0-323-26680-2 ; 0-323-26680-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Web Exclusive. Annals On Call - Low-Dose Colchicine and Incident Knee and Hip Replacements.

    Centor, Robert M / Neogi, Tuhina

    Annals of internal medicine

    2023  Volume 176, Issue 10, Page(s) eA220019

    Language English
    Publishing date 2023-10-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/A22-0019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Repurposing antidiabetic medications for gout: the potential of sodium glucose co-transporter 2 inhibitors.

    Neogi, Tuhina

    The Lancet. Rheumatology

    2019  Volume 1, Issue 4, Page(s) e197–e199

    Language English
    Publishing date 2019-08-28
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(19)30108-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Where are the women 'Heroes and Pillars of Rheumatology'?

    Dalbeth, Nicola / Neogi, Tuhina

    Annals of the rheumatic diseases

    2022  Volume 82, Issue 8, Page(s) e199

    MeSH term(s) Female ; Humans ; Rheumatology ; Arthritis, Rheumatoid ; Gout
    Language English
    Publishing date 2022-02-04
    Publishing country England
    Document type Letter
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2021-222047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A clinician's perspective on the role of imaging in knee osteoarthritis in clinical practice.

    Felson, David / Neogi, Tuhina

    Skeletal radiology

    2023  Volume 52, Issue 11, Page(s) 2007–2010

    Abstract: Knee osteoarthritis (OA) is a highly prevalent and disabling disease. Most persons age 45 and over with chronic knee pain have OA and with characteristic history and physical findings, diagnostic imaging is usually not necessary. Further, treatment of ... ...

    Abstract Knee osteoarthritis (OA) is a highly prevalent and disabling disease. Most persons age 45 and over with chronic knee pain have OA and with characteristic history and physical findings, diagnostic imaging is usually not necessary. Further, treatment of chronic knee pain with or without evidence of OA is similar, so imaging does not usually alter therapy. The exception is atypical presentations, such as sudden onset of pain perhaps after trauma or evidence of arthritis in atypical locations elsewhere in the body. Imaging is also unnecessary to follow patients. Given the absence of treatments that slow progression, there is little rationale for acquiring repeated imaging. However, ultrasound or other knee imaging may be helpful in locating the joint when carrying out intraarticular corticosteroid injections. There is controversy as to whether imaging should be acquired before these injections, but recent studies suggest no increased risk of disease progression for most persons receiving these injections. While guidelines currently discourage imaging in the diagnosis or management of most persons with OA, this may change for individuals with identifiable correctible lesions, when effective treatments that alter progression emerge or when imaging is used to identify subtypes of disease that may respond to specific treatments.
    MeSH term(s) Humans ; Middle Aged ; Osteoarthritis, Knee/diagnostic imaging ; Osteoarthritis, Knee/therapy ; Knee Joint ; Adrenal Cortex Hormones/therapeutic use ; Pain/drug therapy ; Ultrasonography ; Injections, Intra-Articular
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2023-02-02
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 527592-1
    ISSN 1432-2161 ; 0364-2348
    ISSN (online) 1432-2161
    ISSN 0364-2348
    DOI 10.1007/s00256-023-04285-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Placebo effects in osteoarthritis: implications for treatment and drug development.

    Neogi, Tuhina / Colloca, Luana

    Nature reviews. Rheumatology

    2023  Volume 19, Issue 10, Page(s) 613–626

    Abstract: Osteoarthritis (OA) is the most common form of arthritis worldwide, affecting ~500 million people, yet there are no effective treatments to halt its progression. Without any structure-modifying agents, management of OA focuses on ameliorating pain and ... ...

    Abstract Osteoarthritis (OA) is the most common form of arthritis worldwide, affecting ~500 million people, yet there are no effective treatments to halt its progression. Without any structure-modifying agents, management of OA focuses on ameliorating pain and improving function. Treatment approaches typically have modest efficacy, and many patients have contraindications to recommended pharmacological treatments. Drug development for OA is hindered by the gradual and progressive nature of the disease and the targeting of established disease in clinical trials. Additionally, new medications for OA cannot receive regulatory approval without demonstrating improvements in both structure (pathological features of OA) and symptoms (reduced pain and/or improved function). In clinical trials, people with OA show high 'placebo responses', which hamper the ability to identify new effective treatments. Placebo responses refer to the individual variability in response to placebos given in the context of clinical trials and other settings. Placebo effects refer specifically to short-lasting improvements in symptoms that occur because of physiological changes. To mitigate the effects of the placebo phenomenon, we must first understand what it is, how it manifests, how to identify placebo responders in OA trials and how these insights can be used to improve clinical trials in OA. Leveraging placebo responses and effects in clinical practice might provide additional avenues to augment symptom management of OA.
    MeSH term(s) Humans ; Osteoarthritis, Knee/drug therapy ; Placebo Effect ; Pain/drug therapy ; Treatment Outcome ; Drug Development
    Language English
    Publishing date 2023-09-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2491532-4
    ISSN 1759-4804 ; 1759-4790
    ISSN (online) 1759-4804
    ISSN 1759-4790
    DOI 10.1038/s41584-023-01021-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Structural correlates of pain in osteoarthritis.

    Neogi, Tuhina

    Clinical and experimental rheumatology

    2017  Volume 35 Suppl 107, Issue 5, Page(s) 75–78

    Abstract: Osteoarthritis (OA) is the most common form of arthritis, with knee OA itself being among the most common conditions and a leading cause of disability among older adults worldwide. Pain is a key symptom in the decision to seek medical attention, yet ... ...

    Abstract Osteoarthritis (OA) is the most common form of arthritis, with knee OA itself being among the most common conditions and a leading cause of disability among older adults worldwide. Pain is a key symptom in the decision to seek medical attention, yet available therapies for managing OA are limited with only minimal or moderate efficacy. Current approaches to pain management in OA have been rather non-specific, limited to acetaminophen or NSAIDs primarily, without targeting underlying structural lesions that may be contributing to pain in OA. With the advent of MRI, a number of studies have noted the importance of bone marrow lesions and synovitis/effusion to the pain experience in OA. These pathologic features are therefore attractive treatment targets, with some proof-of-concept studies demonstrating the potential efficacy of targeting these lesions. Another increasingly recognised important contribution to pain in OA is sensitisation, which is associated with pain severity. Synovitis/effusion have been identified as potentially leading to development and worsening of sensitisation. Much work remains to be done in understanding the mechanisms by which structural pathology causes pain; such insights are urgently needed to develop new treatment approaches to help millions of people worldwide who are burdened by pain from OA.
    Language English
    Publishing date 2017-09
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
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  8. Article ; Online: Rising Global Burden of Gout: Time to Act.

    Danve, Abhijeet / Neogi, Tuhina

    Arthritis & rheumatology (Hoboken, N.J.)

    2020  Volume 72, Issue 11, Page(s) 1786–1788

    MeSH term(s) Global Burden of Disease ; Gout/epidemiology ; Humans ; Incidence ; Prevalence ; Risk Factors
    Language English
    Publishing date 2020-09-17
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.41453
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  9. Article ; Online: Gout.

    Neogi, Tuhina

    Annals of internal medicine

    2016  Volume 165, Issue 1, Page(s) ITC1–ITC16

    Abstract: This issue provides a clinical overview of gout, focusing on prevention and screening, diagnosis, and treatment. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), ... ...

    Abstract This issue provides a clinical overview of gout, focusing on prevention and screening, diagnosis, and treatment. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance of additional science writers and physician writers.
    MeSH term(s) Diagnosis, Differential ; Gout/diagnosis ; Gout/drug therapy ; Gout/prevention & control ; Humans ; Patient Education as Topic ; Risk Factors
    Language English
    Publishing date 2016-07-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/AITC201607050
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  10. Article ; Online: Osteoarthritis Flares.

    Thomas, Martin J / Guillemin, Francis / Neogi, Tuhina

    Clinics in geriatric medicine

    2022  Volume 38, Issue 2, Page(s) 239–257

    Abstract: The phenomenon of flares is a common feature in the daily life of people with osteoarthritis (OA). Characterized by episodes of sudden-onset increases in signs and symptoms, their impact can often be distressing and disabling. Despite their potential to ... ...

    Abstract The phenomenon of flares is a common feature in the daily life of people with osteoarthritis (OA). Characterized by episodes of sudden-onset increases in signs and symptoms, their impact can often be distressing and disabling. Despite their potential to have both short-term and long-term consequences for patients across the whole course of the condition, their occurrence and optimal management are not fully understood. This article provides a contemporary perspective on defining OA flares and their potential triggers, and offers suggestions for how health professionals might explore flare patterns with patients in clinical practice and frame timely best-practice treatment approaches.
    MeSH term(s) Humans ; Osteoarthritis, Knee
    Language English
    Publishing date 2022-04-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1064151-8
    ISSN 1879-8853 ; 0749-0690
    ISSN (online) 1879-8853
    ISSN 0749-0690
    DOI 10.1016/j.cger.2021.11.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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