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  1. Article ; Online: Resource recovery of high value-added products from wastewater: Current status and prospects.

    Wei, Zihan / Qin, Yan / Li, Xiang / Gao, Pin

    Bioresource technology

    2024  Volume 398, Page(s) 130521

    Abstract: Wastewater resource recovery not only allows the extraction of value-added products and offsets the operational costs of wastewater treatment, but it is also conducive to alleviating adverse environmental issues due to energy and chemical inputs and ... ...

    Abstract Wastewater resource recovery not only allows the extraction of value-added products and offsets the operational costs of wastewater treatment, but it is also conducive to alleviating adverse environmental issues due to energy and chemical inputs and associated emissions. A number of attractive compounds such as alginate-like polymers, struvite, polyhydroxyalkanoates, and sulfated polysaccharides, were found and successfully obtained from wastewater and have a wide range of application prospects. The aim of this work is to provide a comprehensive review of recent advances in recovery of these popular products from wastewater, and their physicochemical properties, main sources, and current recovery status are summarized. Various factors influencing the recovery performance of these materials are thoroughly discussed. Moreover, the research needs and future directions towards wastewater resource recovery are highlighted. This study can provide valuable insights for future research endeavors aiming to improve wastewater resource recovery through the retrieval of high value-added products.
    MeSH term(s) Wastewater ; Sewage ; Waste Disposal, Fluid ; Polyhydroxyalkanoates ; Polysaccharides
    Chemical Substances Wastewater ; Sewage ; Polyhydroxyalkanoates ; Polysaccharides
    Language English
    Publishing date 2024-03-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2024.130521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lycocasine A, a

    Jiang, Shuai / Li, Wen-Yan / Gao, Bei-Bei / Zhao, Qin-Shi

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 7

    Abstract: ... A ... ...

    Abstract A novel
    MeSH term(s) Acid Sensing Ion Channels ; Lycopodium ; Lycopodiaceae ; Alkaloids/pharmacology ; Azacitidine
    Chemical Substances Acid Sensing Ion Channels ; Alkaloids ; Azacitidine (M801H13NRU)
    Language English
    Publishing date 2024-04-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29071581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Development and validation of a risk prediction model for linezolid-induced thrombocytopenia in elderly patients.

    Qin, Yan / Chen, Zhe / Gao, Shuai / Shen, Yun / Ye, Yanrong

    European journal of hospital pharmacy : science and practice

    2024  Volume 31, Issue 2, Page(s) 94–100

    Abstract: Objectives: Linezolid is the first oxazolidinone antimicrobial agent developed for treating multi-drug-resistant gram-positive bacterial infections. The study aimed to investigate the risk factors of linezolid (LI)-induced thrombocytopenia (LI-TP) and ... ...

    Abstract Objectives: Linezolid is the first oxazolidinone antimicrobial agent developed for treating multi-drug-resistant gram-positive bacterial infections. The study aimed to investigate the risk factors of linezolid (LI)-induced thrombocytopenia (LI-TP) and to develop and validate a risk prediction model to identify elderly patients at high risk of developing LI-TP during linezolid therapy.
    Methods: A retrospective cohort study was performed at Zhongshan Hospital, FuDan University, China. The study involved elderly Chinese patients aged ≥65 years administered with linezolid (600 mg) twice a day between January 2015 and April 2021. We collected the patients' clinical characteristics and demographic data from electronic medical records, and compared the differences between LI-TP patients and those who had not developed thrombocytopenia (NO-TP) after linezolid treatment. The risk prediction model was developed based on the regression coefficient generated from logistic regression model.
    Results: A total of 343 inpatients were enrolled from January 2015 to August 2020 and were used as the training set. Among them, 67 (19.5%) developed LI-TP. Multivariate logistic regression analysis revealed that baseline platelet counts <150×10
    Conclusions: These findings indicate that duration of linezolid therapy, age, eGFR, ICU admittance, baseline platelet counts, concomitant piperacillin-tazobactam were significantly associated with LI-TP in elderly patients. A risk prediction model based on these risk factors showed a good discriminative performance and may be useful for clinicians to identify patients at high risk of developing LI-TP.
    MeSH term(s) Aged ; Humans ; Linezolid/adverse effects ; Retrospective Studies ; Thrombocytopenia/chemically induced ; Thrombocytopenia/diagnosis ; Thrombocytopenia/epidemiology ; Oxazolidinones/adverse effects ; Piperacillin, Tazobactam Drug Combination/adverse effects
    Chemical Substances Linezolid (ISQ9I6J12J) ; Oxazolidinones ; Piperacillin, Tazobactam Drug Combination (157044-21-8)
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2650179-X
    ISSN 2047-9964 ; 2047-9956
    ISSN (online) 2047-9964
    ISSN 2047-9956
    DOI 10.1136/ejhpharm-2022-003258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Letter to the editor: Epidemiology of heart failure hospitalization in patients with stable atherothrombotic disease: The contribution of previous heart failure to heart failure hospitalization may be overestimated.

    Mei, Kaibo / Ling, Qin / Gao, Yan / Liu, Xiao / Yan, Zhiwei

    Clinical cardiology

    2023  Volume 46, Issue 3, Page(s) 346–347

    MeSH term(s) Humans ; Heart Failure/epidemiology ; Heart Failure/therapy ; Hospitalization
    Language English
    Publishing date 2023-01-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 391935-3
    ISSN 1932-8737 ; 0160-9289
    ISSN (online) 1932-8737
    ISSN 0160-9289
    DOI 10.1002/clc.23973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Our experience diagnosing 225 patients with cervical glandular lesions: current technologies, lessons learned, and areas for improvement.

    Qin, Yan / Deng, Junyi / Ling, Yuexian / Chen, Tao / Gao, Hongyi

    Diagnostic pathology

    2024  Volume 19, Issue 1, Page(s) 22

    Abstract: Objective: To explore the relative sensitivity of different methods for detecting cervical glandular lesions.: Methods: A total of 225 patients with cervical glandular lesions diagnosed from January 2018 to February 2023 were retrieved from the ... ...

    Abstract Objective: To explore the relative sensitivity of different methods for detecting cervical glandular lesions.
    Methods: A total of 225 patients with cervical glandular lesions diagnosed from January 2018 to February 2023 were retrieved from the pathology database of Guangdong Maternal and Child Health Hospital, and their clinicopathological features were reviewed.
    Results: Four human papillomavirus (HPV) genotypes: HPV18, 16, 45, and 52, dominated all glandular lesions, and accounting for 74.10% of HPV-positive tumors. Furthermore, 36.89% of abnormal squamous cells were diagnosed as abnormal based on cytological examinations leading to the detection of cervical glandular lesions; only 16.89% were diagnosed based on the initial detection of abnormal glandular cytology. The most common abnormal cervical screening result was ASC-US on cytology (14.22%), followed by HSIL (11.56%). Only few number of patients were diagnosed with or suspected of having cervical adenopathy via a Pap test (18.22%). Nearly one-third of cervical glandular lesions cases were not detected on the Pap test; but were diagnosed upon cervical biopsy or based on the histological examination of ECC, LEEP, or CKC specimens. The LEEP or CKC biopsy specimens had negative margins in 49 cases (40.83%), while the margins were positive in the other 71 cases (59.17%). Five cases (10.20%) with negative margins still had residual lesions following total hysterectomy, and 19 (26.76%) with positive margins had no residual lesions after total hysterectomy.
    Conclusion: The ability to detect cervical glandular lesions varies for routine HPV genotyping, Pap test, or biopsy/ECC, with different sensitivities and advantages and disadvantages for each method.
    MeSH term(s) Female ; Child ; Humans ; Uterine Cervical Neoplasms/pathology ; Papillomavirus Infections/complications ; Papillomavirus Infections/diagnosis ; Papillomavirus Infections/pathology ; Early Detection of Cancer/methods ; Papanicolaou Test ; Cervix Uteri/pathology ; Uterine Cervical Dysplasia/pathology ; Papillomaviridae/genetics ; Vaginal Smears/methods
    Language English
    Publishing date 2024-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2210518-9
    ISSN 1746-1596 ; 1746-1596
    ISSN (online) 1746-1596
    ISSN 1746-1596
    DOI 10.1186/s13000-023-01428-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Sunlight-Activated Hour-Long Afterglow from Transparent and Flexible Polymers.

    Zhou, Yusheng / Zhang, Peng / Liu, Zhen / Yan, Wenqing / Gao, Haiyang / Liang, Guodong / Qin, Wei

    Advanced materials (Deerfield Beach, Fla.)

    2024  Volume 36, Issue 16, Page(s) e2312439

    Abstract: Afterglow materials featuring long emission durations ranging from milliseconds to hours have garnered increasing interest owing to their potential applications in sensing, bioimaging, and anti-counterfeiting. Unfortunately, polymeric materials rarely ... ...

    Abstract Afterglow materials featuring long emission durations ranging from milliseconds to hours have garnered increasing interest owing to their potential applications in sensing, bioimaging, and anti-counterfeiting. Unfortunately, polymeric materials rarely exhibit afterglow properties under ambient conditions because of the rapid nonradiative decay rate of triplet excitons. In this study, hour-long afterglow (HLA) polymer films are fabricated using a facile molecular doping strategy. Flexible and transparent polymer films emitted a bright afterglow lasting over 11 h at room temperature in air, which is one of the best performances among the organic afterglow materials reported to date. Intriguingly, HLA polymer films can be activated by sunlight, and their cyan afterglow in air can be readily observed by the naked eye. Moreover, the HLA color of the polymer films could be tuned from cyan to red through the Förster resonance energy transfer mechanism. Their application in flexible displays and information storage has also been demonstrated. With remarkable advantages, including an hour-long and bright afterglow, tunable afterglow colors, superior flexibility and transparency, and ease of fabrication, the HLA polymer paves the way for the practical application of afterglow materials in the engineering sector.
    Language English
    Publishing date 2024-02-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202312439
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Case report: Ewing sarcoma with EWSR-ERG fusion elevates procalcitonin extremely in the long term without infection.

    Chen, Ying / Qin, Tao / Chen, Yan / Gao, Ming

    Frontiers in oncology

    2023  Volume 12, Page(s) 1047738

    Abstract: Background: Ewing sarcoma (ES) represents a rare, aggressive bone and soft-tissue cancer. Unlike breast, liver, pancreatic, and prostate cancers, Ewing sarcoma has had no representative tumor marker until now. The use of procalcitonin (PCT) as a tumor ... ...

    Abstract Background: Ewing sarcoma (ES) represents a rare, aggressive bone and soft-tissue cancer. Unlike breast, liver, pancreatic, and prostate cancers, Ewing sarcoma has had no representative tumor marker until now. The use of procalcitonin (PCT) as a tumor marker is also rarely reported. PCT is a clinically recognized and widely used inflammatory marker in recent years. In rare cases, PCT may also be falsely positive due to non-infectious factors. In the few previously reported papers regarding the correlation between tumors and PCT, we learned that abnormalities of PCT level can also be impacted by individual cancers.
    Case presentation: Here, we first reported a case of Ewing sarcoma with markedly elevated PCT without infection and carried out some literature review. The patient was a middle-aged man with extraskeletal Ewing sarcoma whose lesion was located in the distal abdominal ileum. He had a sudden and unprovoked onset of high fever during chemotherapy before surgery. After multiple examinations, the patient's blood routine, C-reactive protein, blood culture, and CT examination showed no signs of infection, and even the culture from the end of the central venous catheter showed no pathogen growth. Only PCT increased dramatically to more than 200 ng/ml. PCT remained at this level for several months until a single abdominal lumpectomy was performed before it dropped to near-normal levels.
    Conclusion: In our report, PCT is significantly elevated in Ewing sarcoma in the absence of infection. Not only that, but we particularly highlighted the precipitous drop in PCT following tumor resection.
    Language English
    Publishing date 2023-01-13
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.1047738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Transesterification Induced Multifunctional Additives Enable High-Performance Lithium Metal Batteries.

    Gao, Yuanhang / Wu, Gang / Fang, Wenqiang / Qin, Zuosu / Zhang, Tao / Yan, Jiaxing / Zhong, Yunpeng / Zhang, Ning / Chen, Gen

    Angewandte Chemie (International ed. in English)

    2024  , Page(s) e202403668

    Abstract: The electrolyte chemistry is crucially important for promoting the practical application of lithium metal batteries (LMBs). Here, we demonstrate for the first time that 1,3-dimethylimidazolium dimethyl phosphate (DIDP) and trimethylsilyl trifluoroacetate ...

    Abstract The electrolyte chemistry is crucially important for promoting the practical application of lithium metal batteries (LMBs). Here, we demonstrate for the first time that 1,3-dimethylimidazolium dimethyl phosphate (DIDP) and trimethylsilyl trifluoroacetate (TMSF) can undergo in situ transesterification in carbonate electrolyte to generate dimethyl trimethylsilyl phosphate (DTMSP) and 1,3-dimethylimidazolium trifluoroacetate (DITFA) as multifunctional additives for LMBs. H
    Language English
    Publishing date 2024-03-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202403668
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  9. Article ; Online: Generic and accurate prediction of retention times in liquid chromatography by post-projection calibration.

    Zhang, Yan / Liu, Fei / Li, Xiu Qin / Gao, Yan / Li, Kang Cong / Zhang, Qing He

    Communications chemistry

    2024  Volume 7, Issue 1, Page(s) 54

    Abstract: Retention time predictions from molecule structures in liquid chromatography (LC) are increasingly used in MS-based targeted and untargeted analyses, providing supplementary evidence for molecule annotation and reducing experimental measurements. ... ...

    Abstract Retention time predictions from molecule structures in liquid chromatography (LC) are increasingly used in MS-based targeted and untargeted analyses, providing supplementary evidence for molecule annotation and reducing experimental measurements. Nevertheless, different LC setups (e.g., differences in gradient, column, and/or mobile phase) give rise to many prediction models that can only accurately predict retention times for a specific chromatographic method (CM). Here, a generic and accurate method is present to predict retention times across different CMs, by introducing the concept of post-projection calibration. This concept builds on the direct projections of retention times between different CMs and uses 35 external calibrants to eliminate the impact of LC setups on projection accuracy. Results showed that post-projection calibration consistently achieved a median projection error below 3.2% of the elution time. The ranking results of putative candidates reached similar levels among different CMs. This work opens up broad possibilities for coordinating retention times between different laboratories and developing extensive retention databases.
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2929562-2
    ISSN 2399-3669 ; 2399-3669
    ISSN (online) 2399-3669
    ISSN 2399-3669
    DOI 10.1038/s42004-024-01135-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A case report of sepsis and death caused by

    Jiang, Yuhang / Qin, Weichao / Li, Jian / Gao, Yuan / Zeng, Yan

    Frontiers in public health

    2022  Volume 10, Page(s) 994279

    Abstract: Parvimonas ... ...

    Abstract Parvimonas micra
    MeSH term(s) Female ; Firmicutes ; Humans ; Sepsis/diagnosis
    Language English
    Publishing date 2022-09-20
    Publishing country Switzerland
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.994279
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