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  1. Article: Cytomegalovirus Hepatitis in an Immunocompetent Adult.

    Choudhary, Narendra S / Deswal, Vikas / Nehra, Ritu / Gautam, Dheeraj

    Journal of clinical and experimental hepatology

    2022  Volume 13, Issue 1, Page(s) 187–188

    Language English
    Publishing date 2022-09-09
    Publishing country India
    Document type Journal Article
    ISSN 0973-6883
    ISSN 0973-6883
    DOI 10.1016/j.jceh.2022.08.008
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  2. Article: Consequences of Stress on Academic Fraternity: A Meta-analytical Review.

    Gautam, Ritu / Sharma, Manik

    Psychiatria Danubina

    2021  Volume 33, Issue Suppl 10, Page(s) 3–17

    Abstract: Introduction: The modern lifestyle and the dynamic environment are progressively inducing stress among a wide range of individuals like students, healthcare professionals, bankers, engineers, businessmen, administrators and teachers. This vitriolic ... ...

    Abstract Introduction: The modern lifestyle and the dynamic environment are progressively inducing stress among a wide range of individuals like students, healthcare professionals, bankers, engineers, businessmen, administrators and teachers. This vitriolic human psychiatric disorder has put the academic fraternity in a shabby state.
    Methods: The methodology adopted in this article is comprised of three phases such as review planning, review conducting, and review reporting.
    Results: The main emphasis of this extensive study is to highlight the major stressors and consequences of stress among the academic fraternity. Firstly, different categories of stress and their repercussions on the human body have been outlined. Additionally, the comprehensive publishing trend of the related manuscripts pertinent to stress among the academic fraternity has also been reported. The research implications and future directions have been also outlined.
    Conclusion: Finally, some major research breaches are analyzed and it is witnessed that there is prospective scope in the diagnosis of stress among students and teachers using emerging soft computing and deep learning techniques.
    MeSH term(s) Humans ; Mental Disorders ; Prospective Studies ; Stress, Psychological ; Students
    Language English
    Publishing date 2021-10-21
    Publishing country Croatia
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 1067580-2
    ISSN 0353-5053
    ISSN 0353-5053
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3158: Show issues Location:
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  3. Article ; Online: Unlocking β-cell restoration: The crucial role of PDX1 in diabetes therapy.

    Siwan, Deepali / Nandave, Mukesh / Gilhotra, Ritu / Almalki, Waleed Hassan / Gupta, Gaurav / Gautam, Rupesh K

    Pathology, research and practice

    2024  Volume 254, Page(s) 155131

    Abstract: Diabetes has been a significant healthcare problem worldwide for a considerable period. The primary objective of diabetic treatment plans is to control the symptoms associated with the pathology. To effectively combat diabetes, it is crucial to ... ...

    Abstract Diabetes has been a significant healthcare problem worldwide for a considerable period. The primary objective of diabetic treatment plans is to control the symptoms associated with the pathology. To effectively combat diabetes, it is crucial to comprehend the disease's etiology, essential factors, and the relevant processes involving β-cells. The development of the pancreas, maturation, and maintenance of β-cells, and their role in regular insulin function are all regulated by PDX1. Therefore, understanding the regulation of PDX1 and its interactions with signaling pathways involved in β-cell differentiation and proliferation are crucial elements of alternative diabetes treatment strategies. The present review aims to explore the protective role of PDX1 in β-cell proliferation through signaling pathways. The main keywords chosen for this review include "PDX1 for β-cell mass," "β-cell proliferation," "β-cell restoration via PDX1," and "mechanism of PDX1 in β-cells." A comprehensive literature search was conducted using various internet search engines, such as PubMed, Science Direct, and other publication databases. We summarize several approaches to generating β-cells from alternative cell sources, employing PDX1 under various modified growth conditions and different transcriptional factors. Our analysis highlights the unique potential of PDX1 as a promising target in molecular and cell-based therapies for diabetes.
    MeSH term(s) Humans ; Diabetes Mellitus/therapy ; Diabetes Mellitus/metabolism ; Homeodomain Proteins/metabolism ; Insulin-Secreting Cells/metabolism ; Trans-Activators/metabolism ; Transcription Factors/metabolism
    Chemical Substances Homeodomain Proteins ; Trans-Activators ; Transcription Factors ; pancreatic and duodenal homeobox 1 protein
    Language English
    Publishing date 2024-01-20
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 391889-0
    ISSN 1618-0631 ; 0344-0338
    ISSN (online) 1618-0631
    ISSN 0344-0338
    DOI 10.1016/j.prp.2024.155131
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  4. Article ; Online: 2019-nCoV pandemic: A disruptive and stressful atmosphere for Indian academic fraternity.

    Gautam, Ritu / Sharma, Manik

    Brain, behavior, and immunity

    2020  Volume 88, Page(s) 948–949

    MeSH term(s) Betacoronavirus ; Biomedical Research ; COVID-19 ; Coronavirus Infections/epidemiology ; Education, Distance ; Faculty/psychology ; Humans ; India/epidemiology ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Stress, Psychological/psychology ; Students/psychology ; Universities
    Keywords covid19
    Language English
    Publishing date 2020-04-11
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 639219-2
    ISSN 1090-2139 ; 0889-1591
    ISSN (online) 1090-2139
    ISSN 0889-1591
    DOI 10.1016/j.bbi.2020.04.025
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    Zs.A 2276: Show issues Location:
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    Zs.MO 327: Show issues

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  5. Article ; Online: Efflux pump inhibitory potential of indole derivatives as an arsenal against

    Chandal, Nishtha / Tambat, Rushikesh / Kalia, Ritu / Kumar, Gautam / Mahey, Nisha / Jachak, Sanjay / Nandanwar, Hemraj

    Microbiology spectrum

    2023  , Page(s) e0487622

    Abstract: NorA, an extensively studied efflux pump ... ...

    Abstract NorA, an extensively studied efflux pump in
    Language English
    Publishing date 2023-09-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.04876-22
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  6. Article ; Online: Prevalence and Diagnosis of Neurological Disorders Using Different Deep Learning Techniques: A Meta-Analysis.

    Gautam, Ritu / Sharma, Manik

    Journal of medical systems

    2020  Volume 44, Issue 2, Page(s) 49

    Abstract: This paper dispenses an exhaustive review on deep learning techniques used in the prognosis of eight different neuropsychiatric and neurological disorders such as stroke, alzheimer, parkinson's, epilepsy, autism, migraine, cerebral palsy, and multiple ... ...

    Abstract This paper dispenses an exhaustive review on deep learning techniques used in the prognosis of eight different neuropsychiatric and neurological disorders such as stroke, alzheimer, parkinson's, epilepsy, autism, migraine, cerebral palsy, and multiple sclerosis. These diseases are critical, life-threatening and in most of the cases may lead to other precarious human disorders. Deep learning techniques are emerging soft computing technique which has been lucratively used to unravel different real-life problems such as pattern recognition (Face, Emotion, and Speech), traffic management, drug discovery, disease diagnosis, and network intrusion detection. This study confers the discipline, frameworks, and methodologies used by different deep learning techniques to diagnose different human neurological disorders. Here, one hundred and thirty-six different articles related to neurological and neuropsychiatric disorders diagnosed using different deep learning techniques are studied. The morbidity and mortality rate of major neuropsychiatric and neurological disorders has also been delineated. The performance and publication trend of different deep learning techniques employed in the investigation of these diseases has been examined and analyzed. Different performance metrics like accuracy, specificity, and sensitivity have also been examined. The research implication, challenges and the future directions related to the study have also been highlighted. Eventually, the research breaches are identified and it is witnessed that there is more scope in the diagnosis of migraine, cerebral palsy and stroke using different deep learning models. Likewise, there is a potential opportunity to use and explore the performance of Restricted Boltzmann Machine, Deep Boltzmann Machine and Deep Belief Network for diagnosis of different human neuropsychiatric and neurological disorders.
    MeSH term(s) Deep Learning ; Humans ; Image Processing, Computer-Assisted ; Nervous System Diseases/diagnosis ; Nervous System Diseases/epidemiology ; Nervous System Diseases/mortality ; Neural Networks, Computer ; Prevalence ; Sensitivity and Specificity
    Language English
    Publishing date 2020-01-04
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 423488-1
    ISSN 1573-689X ; 0148-5598
    ISSN (online) 1573-689X
    ISSN 0148-5598
    DOI 10.1007/s10916-019-1519-7
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    Zs.A 1426: Show issues Location:
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  7. Article ; Online: Metal organic frameworks for electrochemical sensor applications: A review.

    Kajal, Navdeep / Singh, Vishavjeet / Gupta, Ritu / Gautam, Sanjeev

    Environmental research

    2021  Volume 204, Issue Pt C, Page(s) 112320

    Abstract: Metal-organic frameworks (MOFs) are broadly known as porous coordination polymers, synthesized by metal-based nodes and organic linkers. MOFs are used in various fields like catalysis, energy storage, sensors, drug delivery etc., due to their versatile ... ...

    Abstract Metal-organic frameworks (MOFs) are broadly known as porous coordination polymers, synthesized by metal-based nodes and organic linkers. MOFs are used in various fields like catalysis, energy storage, sensors, drug delivery etc., due to their versatile properties (tailorable pore size, high surface area, and exposed active sites). This review presents a detailed discussion of MOFs as an electrochemical sensor and their enhancement in the selectivity and sensitivity of the sensor. These sensors are used for the detection of heavy metal ions like Cd
    MeSH term(s) Catalysis ; Environmental Pollutants ; Ions ; Metal-Organic Frameworks ; Metals, Heavy/chemistry
    Chemical Substances Environmental Pollutants ; Ions ; Metal-Organic Frameworks ; Metals, Heavy
    Language English
    Publishing date 2021-11-02
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2021.112320
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    Zs.A 726: Show issues Location:
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  9. Article: Metal organic frameworks for electrochemical sensor applications: A review

    Kajal, Navdeep / Singh, Vishavjeet / Gupta, Ritu / Gautam, Sanjeev

    Environmental research. 2022 Mar., v. 204

    2022  

    Abstract: Metal-organic frameworks (MOFs) are broadly known as porous coordination polymers, synthesized by metal-based nodes and organic linkers. MOFs are used in various fields like catalysis, energy storage, sensors, drug delivery etc., due to their versatile ... ...

    Abstract Metal-organic frameworks (MOFs) are broadly known as porous coordination polymers, synthesized by metal-based nodes and organic linkers. MOFs are used in various fields like catalysis, energy storage, sensors, drug delivery etc., due to their versatile properties (tailorable pore size, high surface area, and exposed active sites). This review presents a detailed discussion of MOFs as an electrochemical sensor and their enhancement in the selectivity and sensitivity of the sensor. These sensors are used for the detection of heavy metal ions like Cd²⁺, Pb²⁺, Hg²⁺, and Cu²⁺ from groundwater. Various types of organic pollutants are also detected from the water bodies using MOFs. Furthermore, electrochemical sensing of antibiotics, phenolic compounds, and pesticides has been explored. In addition to this, there is also a detailed discussion of metal nano-particles and metal-oxide based composites which can sense various compounds like glucose, amino acids, uric acid etc. The review will be helpful for young researchers, and an inspiration to future research as challenges and future opportunities of MOF-based electrochemical sensors are also reported.
    Keywords catalytic activity ; drugs ; electrochemistry ; energy ; glucose ; groundwater ; heavy metals ; porosity ; research ; sensors (equipment) ; surface area ; uric acid
    Language English
    Dates of publication 2022-03
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2021.112320
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  10. Article ; Online: Synergistic Effect of Plasticizer and Cross‐Linking Agent on the Properties of Finger Millet Starch‐Based Film

    Sharma, Ritu / Gautam, Naina / Giribabu, Giribabu / Kumar, Raj / Yadav, Shashikant

    Starch ‐ Stärke. 2023 Sept., v. 75, no. 9-10 p.e2200251-

    2023  

    Abstract: Edible films can be used for food packaging to extend the shelf life of foods and protect them from exposure to moisture, microorganisms, pathogens, and bacteria. In the present study, the effect of plasticization and cross‐linking, which are ... ...

    Abstract Edible films can be used for food packaging to extend the shelf life of foods and protect them from exposure to moisture, microorganisms, pathogens, and bacteria. In the present study, the effect of plasticization and cross‐linking, which are modification approaches for upgrading the properties of starch, are investigated. Glycerol and sorbitol are used as plasticizing agents, and succinic acid is used as a cross‐linking agent. The results demonstrate that the addition of glycerol and sorbitol to the film‐forming solutions reduces brittleness and increases peeling ability and flexibility upon drying. Furthermore, the film matrix supports improvements in water vapor permeability (WVP), swelling index (SI), and mechanical properties. The glycerol‐based finger millet starch (FMS) films exhibits better thermal stability than the sorbitol‐based FMS film. The microscopic images of the films show that the use of glycerol in the film improves compactness and homogeneity compared to sorbitol‐based FMS films.
    Keywords Eleusine coracana ; brittleness ; cross-linking reagents ; crosslinking ; glycerol ; permeability ; plasticizers ; shelf life ; sorbitol ; starch ; succinic acid ; synergism ; thermal stability ; water vapor
    Language English
    Dates of publication 2023-09
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 241168-4
    ISSN 0038-9056
    ISSN 0038-9056
    DOI 10.1002/star.202200251
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