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  1. Article ; Online: Beyond the

    Chang, Kevin J / Yee, Judy

    AJR. American journal of roentgenology

    2023  Volume 221, Issue 2, Page(s) 279

    MeSH term(s) Humans ; Colonography, Computed Tomographic ; Early Detection of Cancer ; Colonoscopy ; Colorectal Neoplasms/diagnosis ; Occult Blood
    Language English
    Publishing date 2023-01-04
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.22.28821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Identifying a Biliary Origin of Acute Pancreatitis Using CT.

    Chang, Kevin J

    Radiology

    2021  Volume 302, Issue 1, Page(s) 127–128

    MeSH term(s) Acute Disease ; Cholangiopancreatography, Endoscopic Retrograde ; Gallstones ; Humans ; Pancreatitis/diagnostic imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-10-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.2021212066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reply.

    Chen, Jefferson C / LeBedis, Christina A / Chang, Kevin J

    Journal of the American College of Radiology : JACR

    2023  Volume 21, Issue 4, Page(s) 544

    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Letter
    ZDB-ID 2274861-1
    ISSN 1558-349X ; 1546-1440
    ISSN (online) 1558-349X
    ISSN 1546-1440
    DOI 10.1016/j.jacr.2023.09.008
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  4. Article ; Online: The Public Perception of CT Colonography Versus Colonoscopy via Sentiment Analysis of Social Media.

    Chen, Jefferson C / LeBedis, Christina A / Chang, Kevin J

    Journal of the American College of Radiology : JACR

    2023  Volume 20, Issue 6, Page(s) 531–536

    Abstract: Purpose: The purpose of this study was to understand the public perception of CT colonography (CTC) in comparison with optical colonoscopy as a colorectal cancer screening technique.: Methods: In this observational study, all English-language tweets ... ...

    Abstract Purpose: The purpose of this study was to understand the public perception of CT colonography (CTC) in comparison with optical colonoscopy as a colorectal cancer screening technique.
    Methods: In this observational study, all English-language tweets from January 1, 2015, until September 1, 2021, containing terms related to CTC and terms related to optical colonoscopy were collected. The tweets were given sentiment scores using Twitter-roBERTa-base, a natural language processing model. These scores were then used to classify tweets into positive, neutral, and negative categories. The numbers of negative, positive, and neutral tweets were tabulated.
    Results: A total of 4,709 tweets from 2,194 users relating to CTC were collected. Of these tweets, 9.81% were negative, 68.52% were neutral, and 21.63% were positive. In comparison, a total of 445,969 tweets from 261,209 users were collected relating to optical colonoscopy. Of these tweets, 31.8% were negative, 51.3% were neutral, and 16.9% were positive.
    Conclusions: The public awareness of CTC remains limited in comparison with optical colonoscopy, with Twitter volume relating to CTC being about 1% the volume for optical colonoscopy. There was a higher proportion of negative tweets regarding colonoscopy. The lower proportion of negative tweets regarding CTC may be helpful in encouraging its use as an alternative to optical colonoscopy, with the aim of increasing uptake of colorectal cancer screening.
    MeSH term(s) Humans ; Colonography, Computed Tomographic ; Social Media ; Public Opinion ; Sentiment Analysis ; Colonoscopy ; Colorectal Neoplasms/diagnostic imaging
    Language English
    Publishing date 2023-04-29
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 2274861-1
    ISSN 1558-349X ; 1546-1440
    ISSN (online) 1558-349X
    ISSN 1546-1440
    DOI 10.1016/j.jacr.2023.03.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Evaluating the Effectiveness of School Closure in COVID-19-Related Syndromes From Community-Based Syndromic Surveillance: Longitudinal Observational Study.

    Chung, Ping-Chen / Chen, Kevin J / Chang, Hui-Mei / Chan, Ta-Chien

    Interactive journal of medical research

    2023  Volume 12, Page(s) e44606

    Abstract: Background: During the COVID-19 pandemic, a school closure policy was adopted to prevent cluster transmission in schools and subsequent household transmission. However, the effectiveness of school closure is not consistent in studies conducted in ... ...

    Abstract Background: During the COVID-19 pandemic, a school closure policy was adopted to prevent cluster transmission in schools and subsequent household transmission. However, the effectiveness of school closure is not consistent in studies conducted in different countries.
    Objective: This study aimed to explore the association between school closure and the daily standardized incidence of COVID-19-related syndromes in an outpatient syndromic surveillance system.
    Methods: We calculated the incidence of COVID-19-related syndromes derived from a community-based syndromic surveillance system between the first week of January and the second or fourth weeks after school closure in 2021 and 2022 in Taipei City, Taiwan. The effect of school closure on the standardized incidence of COVID-19-related syndromes was evaluated by interrupted time series analysis using an autoregressive integrated moving average with a distributed lag function. The exogenous variables were changes in human mobility measured by Google COVID-19 community mobility reports. Furthermore, the models quantified the influence of different age groups and the hierarchy of medical facilities, such as clinics or community hospitals.
    Results: School closure was only negatively and significantly associated with the overall standardized incidence of COVID-19-related syndromes in 2021 for 2 weeks after the intervention (coefficient -1.24, 95% CI -2.40 to -0.08). However, in different age groups, school closure had a significantly negative association with the standardized incidence among people aged 13-18 years and ≥65 years for 2 weeks after the intervention in clinics in 2021. In community hospitals, school closure was significantly positively associated with the standardized incidence among people aged 19-24 years in 2021. In 2022, 2 weeks after the intervention, school closure had a significantly negative association with the standardized incidence among people aged 0-6, 7-12, and 19-24 years in community hospitals and aged >45 years in clinics. Furthermore, the standardized incidence was positively associated with movement change toward grocery and pharmacy stores in all age groups in 2022. In addition, movement changes toward residences were significantly positively associated with the standardized incidence among all age groups.
    Conclusions: Overall, school closure effectively suppresses COVID-19-related syndromes in students owing to the reduction of physical contact. In addition, school closure has a spillover effect on elderly people who stay at home.
    Language English
    Publishing date 2023-12-15
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2697014-4
    ISSN 1929-073X
    ISSN 1929-073X
    DOI 10.2196/44606
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Therapeutic synthetic and natural materials for immunoengineering.

    Slezak, Anna / Chang, Kevin / Hossainy, Samir / Mansurov, Aslan / Rowan, Stuart J / Hubbell, Jeffrey A / Guler, Mustafa O

    Chemical Society reviews

    2024  Volume 53, Issue 4, Page(s) 1789–1822

    Abstract: Immunoengineering is a rapidly evolving field that has been driving innovations in manipulating immune system for new treatment tools and methods. The need for materials for immunoengineering applications has gained significant attention in recent years ... ...

    Abstract Immunoengineering is a rapidly evolving field that has been driving innovations in manipulating immune system for new treatment tools and methods. The need for materials for immunoengineering applications has gained significant attention in recent years due to the growing demand for effective therapies that can target and regulate the immune system. Biologics and biomaterials are emerging as promising tools for controlling immune responses, and a wide variety of materials, including proteins, polymers, nanoparticles, and hydrogels, are being developed for this purpose. In this review article, we explore the different types of materials used in immunoengineering applications, their properties and design principles, and highlight the latest therapeutic materials advancements. Recent works in adjuvants, vaccines, immune tolerance, immunotherapy, and tissue models for immunoengineering studies are discussed.
    MeSH term(s) Immunotherapy ; Vaccines ; Biocompatible Materials/therapeutic use ; Proteins
    Chemical Substances Vaccines ; Biocompatible Materials ; Proteins
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1472875-8
    ISSN 1460-4744 ; 0306-0012
    ISSN (online) 1460-4744
    ISSN 0306-0012
    DOI 10.1039/d3cs00805c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Bouveret Syndrome: A Rare Case of Instance and Treatment in a Younger Patient.

    Yang, Kevin J / Chang, C K

    Case reports in gastrointestinal medicine

    2020  Volume 2020, Page(s) 1837387

    Abstract: Bouveret syndrome, a specific form of gallstone ileus, is the obstruction of the gastric outlet by a gallstone, which can enter the duodenum through a fistula. While the average age of individuals with Bouveret syndrome is 74 years, our patient was 42 ... ...

    Abstract Bouveret syndrome, a specific form of gallstone ileus, is the obstruction of the gastric outlet by a gallstone, which can enter the duodenum through a fistula. While the average age of individuals with Bouveret syndrome is 74 years, our patient was 42 years of age at the time of operation, significantly younger than the average patient afflicted with this condition. In the treatment of our patient's condition, the operation conducted entailed a partial duodenectomy, gastrojejunostomy, cholecystectomy, common bile duct exploration, extraction of bile duct stones, and insertion of a t-tube in the bile duct. The patient was found to be in healthy condition upon check-up six months after the operation. The outcome of our case suggests that younger Bouveret patients can safely undergo multiple surgical procedures in the treatment of Bouveret syndrome. Our case also suggests that a cholecystectomy and the removal of the obstructing gallstone can both be carried out within one operation, although coupling these two procedures in one operation might be riskier for patients within the normal age range of Bouveret syndrome. We also suggest that fistula repair be carried out for younger Bouveret patients in particular and that the patient be subjected to a CT scan in the diagnosis of Bouveret syndrome when this condition is suspected.
    Language English
    Publishing date 2020-03-16
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627636-7
    ISSN 2090-6536 ; 2090-6528
    ISSN (online) 2090-6536
    ISSN 2090-6528
    DOI 10.1155/2020/1837387
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  8. Article ; Online: Imaging of colon and rectal cancer.

    Lee, Sonia / Surabhi, Venkateswar R / Kassam, Zahra / Chang, Kevin J / Kaur, Harmeet

    Current problems in cancer

    2023  Volume 47, Issue 2, Page(s) 100970

    Abstract: Colon and rectal cancer imaging has traditionally been performed to assess for distant disease (typically lung and liver metastases) and to assess the resectability of the primary tumor. With technological and scientific advances in imaging and the ... ...

    Abstract Colon and rectal cancer imaging has traditionally been performed to assess for distant disease (typically lung and liver metastases) and to assess the resectability of the primary tumor. With technological and scientific advances in imaging and the evolution of treatment options, the role of imaging has expanded. Radiologists are now expected to provide a precise description of primary tumor invasion extent, including adjacent organ invasion, involvement of the surgical resection plane, extramural vascular invasion, lymphadenopathy, and response to neoadjuvant treatment, and to monitor for recurrence after clinical complete response.
    MeSH term(s) Humans ; Neoplasm Staging ; Rectal Neoplasms/diagnostic imaging ; Rectal Neoplasms/therapy ; Rectal Neoplasms/pathology ; Magnetic Resonance Imaging ; Tomography, X-Ray Computed ; Neoadjuvant Therapy/methods ; Colon/pathology
    Language English
    Publishing date 2023-06-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 441816-5
    ISSN 1535-6345 ; 0147-0272
    ISSN (online) 1535-6345
    ISSN 0147-0272
    DOI 10.1016/j.currproblcancer.2023.100970
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  9. Article ; Online: Re: Titan AL, Chang J, Megerle K, Murray P, Hammert W. State of the art review: The management of chronic vascular disorders in the hand and upper limb. J Hand Surg Eur. 2023: 48: 295-302.

    Goodman, Daire / Kennedy, Sharon / Cronin, Kevin / Dolan, Roisin / Titan, Ashley L / Chang, James / Megerle, Kai / Murray, Peter / Hammert, Warren

    The Journal of hand surgery, European volume

    2023  Volume 48, Issue 11, Page(s) 1246–1248

    MeSH term(s) Humans ; Upper Extremity ; Hand
    Language English
    Publishing date 2023-07-03
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2272801-6
    ISSN 2043-6289 ; 1753-1934
    ISSN (online) 2043-6289
    ISSN 1753-1934
    DOI 10.1177/17531934231185094
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  10. Article ; Online: Sociodemographic Factors and Screening CT Colonography Use Among Medicare Beneficiaries.

    Christensen, Eric W / Sanelli, Pina C / Rula, Elizabeth Y / Chang, Kevin J / Moreno, Courtney C / Bruining, David H / Yee, Judy

    AJR. American journal of roentgenology

    2023  Volume 222, Issue 1, Page(s) e2329703

    Abstract: BACKGROUND. ...

    Abstract BACKGROUND.
    MeSH term(s) Humans ; Male ; Female ; Aged ; United States ; Middle Aged ; Aged, 80 and over ; Colonography, Computed Tomographic ; Retrospective Studies ; Sociodemographic Factors ; Medicare ; Colonoscopy ; Mass Screening/methods ; Colorectal Neoplasms/diagnostic imaging ; Early Detection of Cancer/methods
    Language English
    Publishing date 2023-07-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.23.29703
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