Article ; Online: Predicting chronological age based on age-related osteophyte development in the superior and inferior vertebral centrum margins of T12-L5.
2023 Volume 69, Issue 1, Page(s) 18–27
Abstract: The purpose of this study was to determine the relationship between vertebral margins at individual vertebral levels between T12-L5 vertebra and chronological age and develop predictive models. Three hundred and nineteen CT scans from a medical imaging ... ...
Abstract | The purpose of this study was to determine the relationship between vertebral margins at individual vertebral levels between T12-L5 vertebra and chronological age and develop predictive models. Three hundred and nineteen CT scans from a medical imaging database in North America were randomly selected. Three superior and inferior vertebral margin sites were scored based on observable age-related changes. All individual vertebral margin site scores significantly correlated with age at death with Pearson r values ranging from 0.47 to 0.77. Totaling the individual vertebral margin site scores for L1-L5 improved Pearson r to 0.92. All resulting predictive models were significant, and the best models predicted age at death within 10 years 70%-76% of the time for males, females, and combined male and females. In conclusion, this study produced accurate and reliable models to predict age at death using age-related changes in the spine for a North American population. |
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MeSH term(s) | Female ; Male ; Humans ; Osteophyte/diagnostic imaging ; Vertebral Body ; Lumbar Vertebrae ; Thoracic Vertebrae ; Radiography |
Language | English |
Publishing date | 2023-10-18 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 219216-0 |
ISSN | 1556-4029 ; 0022-1198 |
ISSN (online) | 1556-4029 |
ISSN | 0022-1198 |
DOI | 10.1111/1556-4029.15406 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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