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  1. Article: 17β-Estradiol Effects in Skeletal Muscle: A

    Ren, Jimin / Rodriguez, Luis / Johnson, Talon / Henning, Anke / Dhaher, Yasin Y

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 3

    Abstract: The natural variation in estrogen secretion throughout the female menstrual cycle impacts various organs, including estrogen receptor (ER)-expressed skeletal muscle. Many women commonly experience increased fatigue or reduced energy levels in the days ... ...

    Abstract The natural variation in estrogen secretion throughout the female menstrual cycle impacts various organs, including estrogen receptor (ER)-expressed skeletal muscle. Many women commonly experience increased fatigue or reduced energy levels in the days leading up to and during menstruation, when blood estrogen levels decline. Yet, it remains unclear whether endogenous 17β-estradiol, a major estrogen component, directly affects the energy metabolism in skeletal muscle due to the intricate and fluctuating nature of female hormones. In this study, we employed 2D
    Language English
    Publishing date 2024-01-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14030235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chikungunya in Zhejiang Province, Southeast China.

    Ren, Jiangping / Ling, Feng / Liu, Ying / Sun, Jimin

    Infectious medicine

    2023  Volume 2, Issue 4, Page(s) 315–323

    Abstract: Background: Chikungunya is emerging and reemerging word-widely in the past decades. It is non-endemic in Zhejiang Province, Southeast China. Aedes albopictus, one of major vectors of chikungunya, is widely-distribution in Zhejiang, and autochthonous ... ...

    Abstract Background: Chikungunya is emerging and reemerging word-widely in the past decades. It is non-endemic in Zhejiang Province, Southeast China. Aedes albopictus, one of major vectors of chikungunya, is widely-distribution in Zhejiang, and autochthonous transmission is possible after introducing chikungunya virus.
    Methods: Retrospectively collected the epidemiological, clinical and genetic data of chikungunya and conducted the descriptive analysis and gene sequence analysis.
    Results: From 2008 to 2022, 29 chikungunya cases, including 26 overseas imported and 3 local cases, were reported and no cases died of chikungunya. More than half of the imported cases (53.85%) were from Southeast Asia. Seasonal peak of the imported cases was noted between August and September, and 42.31% cases onset in those 2 months. Eight prefecture-level cities and 16 counties reported cases during the study period, with Jinghua (27.59%) and Hangzhou (24.14%) reporting the largest number of cases. The 3 local cases were all reported in Qujiang, Quzhou in 2017. For imported cases, the male-female gender ratio was 2.71:1, 20-30 years old cases (46.15%) and commercial service (42.31%) accounted for the highest proportion. Clinically, fever (100%), fatigue (94.44%), arthralgia (79.17%), headache (71.43%) and erythra (65.22%) were the most common reported symptoms. Eight whole-genome sequences were obtained and belonged to East/Central/South African (ECSA) or Asian genotype.
    Conclusions: With the change of immigration policy, the surveillance of chikungunya should be strengthened and the ability of the case discovery and diagnosis should be improved in Zhejiang in the post-COVID-19 era.
    Language English
    Publishing date 2023-11-17
    Publishing country China
    Document type Journal Article
    ISSN 2772-431X
    ISSN (online) 2772-431X
    DOI 10.1016/j.imj.2023.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Deglacial Subantarctic CO

    Dai, Yuhao / Yu, Jimin / Ren, Haojia / Ji, Xuan

    Nature communications

    2022  Volume 13, Issue 1, Page(s) 5193

    Abstract: The Subantarctic Southern Ocean has long been thought to be an important contributor to increases in atmospheric carbon dioxide partial pressure ( ... ...

    Abstract The Subantarctic Southern Ocean has long been thought to be an important contributor to increases in atmospheric carbon dioxide partial pressure (pCO
    MeSH term(s) Atmosphere ; Carbon Dioxide/metabolism ; Membrane Transport Proteins ; Solubility ; Water
    Chemical Substances Membrane Transport Proteins ; Water (059QF0KO0R) ; Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2022-09-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-022-32895-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: ATP line splitting in association with reduced intracellular magnesium and pH: a brain

    Ren, Jimin / Yu, Fang / Greenberg, Benjamin M

    NMR in biomedicine

    2022  Volume 36, Issue 2, Page(s) e4836

    Abstract: Over the past four decades, ATP, the obligatory energy molecule for keeping all cells alive and functioning, has been thought to contribute only one set of signals in ... ...

    Abstract Over the past four decades, ATP, the obligatory energy molecule for keeping all cells alive and functioning, has been thought to contribute only one set of signals in brain
    MeSH term(s) Myelin-Oligodendrocyte Glycoprotein ; Magnesium ; Brain/diagnostic imaging ; Adenosine Triphosphate ; Hydrogen-Ion Concentration
    Chemical Substances Myelin-Oligodendrocyte Glycoprotein ; Magnesium (I38ZP9992A) ; Adenosine Triphosphate (8L70Q75FXE)
    Language English
    Publishing date 2022-10-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1000976-0
    ISSN 1099-1492 ; 0952-3480
    ISSN (online) 1099-1492
    ISSN 0952-3480
    DOI 10.1002/nbm.4836
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: 31

    Ren, Jimin / Sherry, A Dean

    NMR in biomedicine

    2021  Volume 34, Issue 10, Page(s) e4576

    Abstract: Guanosine diphosphate mannose (GDP-Man) is the donor substrate required for mannosylation in the synthesis of glycoproteins, glycolipids and the newly discovered glycoRNA. Normal GDP-Man biosynthesis plays a crucial role in support of a variety of ... ...

    Abstract Guanosine diphosphate mannose (GDP-Man) is the donor substrate required for mannosylation in the synthesis of glycoproteins, glycolipids and the newly discovered glycoRNA. Normal GDP-Man biosynthesis plays a crucial role in support of a variety of cellular functions, including cell recognition, cell communication and immune responses against viruses. Here, we report the detection of GDP-Man in human brain for the first time, using
    MeSH term(s) Adult ; Aged ; Brain/diagnostic imaging ; Female ; Guanosine Diphosphate Mannose/analysis ; Guanosine Diphosphate Mannose/chemistry ; Humans ; Magnetic Resonance Spectroscopy ; Male ; Middle Aged ; Phosphorus ; Reproducibility of Results ; Uridine Diphosphate/metabolism ; Young Adult
    Chemical Substances Phosphorus (27YLU75U4W) ; Guanosine Diphosphate Mannose (3123-67-9) ; Uridine Diphosphate (58-98-0)
    Language English
    Publishing date 2021-06-21
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1000976-0
    ISSN 1099-1492 ; 0952-3480
    ISSN (online) 1099-1492
    ISSN 0952-3480
    DOI 10.1002/nbm.4576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Deglacial Subantarctic CO2 outgassing driven by a weakened solubility pump

    Yuhao Dai / Jimin Yu / Haojia Ren / Xuan Ji

    Nature Communications, Vol 13, Iss 1, Pp 1-

    2022  Volume 9

    Abstract: Using paired reconstructions of seawater pCO2, temperature, and nutrient utilization, Dai et al. show underappreciated influences of the solubility pump on deglacial Subantarctic surface-water pCO2 variabilities compared to the biological pump. ...

    Abstract Using paired reconstructions of seawater pCO2, temperature, and nutrient utilization, Dai et al. show underappreciated influences of the solubility pump on deglacial Subantarctic surface-water pCO2 variabilities compared to the biological pump.
    Keywords Science ; Q
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: 1

    Chan, Kimberly L / Panatpur, Aparna / Messahel, Souad / Dahshi, Hamza / Johnson, Talon / Henning, Anke / Ren, Jimin / Minassian, Berge A

    Brain communications

    2024  Volume 6, Issue 2, Page(s) fcae104

    Abstract: Lafora disease is a fatal teenage-onset progressive myoclonus epilepsy and neurodegenerative disease associated with polyglucosan bodies. Polyglucosans are long-branched and as a result precipitation- and aggregation-prone glycogen. In mouse models, ... ...

    Abstract Lafora disease is a fatal teenage-onset progressive myoclonus epilepsy and neurodegenerative disease associated with polyglucosan bodies. Polyglucosans are long-branched and as a result precipitation- and aggregation-prone glycogen. In mouse models, downregulation of glycogen synthase, the enzyme that elongates glycogen branches, prevents polyglucosan formation and rescues Lafora disease. Mouse work, however, has not yet revealed the mechanisms of polyglucosan generation, and few
    Language English
    Publishing date 2024-03-26
    Publishing country England
    Document type Journal Article
    ISSN 2632-1297
    ISSN (online) 2632-1297
    DOI 10.1093/braincomms/fcae104
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: High-Resolution Swin Transformer for Automatic Medical Image Segmentation.

    Wei, Chen / Ren, Shenghan / Guo, Kaitai / Hu, Haihong / Liang, Jimin

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 7

    Abstract: The resolution of feature maps is a critical factor for accurate medical image segmentation. Most of the existing Transformer-based networks for medical image segmentation adopt a U-Net-like architecture, which contains an encoder that converts the high- ... ...

    Abstract The resolution of feature maps is a critical factor for accurate medical image segmentation. Most of the existing Transformer-based networks for medical image segmentation adopt a U-Net-like architecture, which contains an encoder that converts the high-resolution input image into low-resolution feature maps using a sequence of Transformer blocks and a decoder that gradually generates high-resolution representations from low-resolution feature maps. However, the procedure of recovering high-resolution representations from low-resolution representations may harm the spatial precision of the generated segmentation masks. Unlike previous studies, in this study, we utilized the high-resolution network (HRNet) design style by replacing the convolutional layers with Transformer blocks, continuously exchanging feature map information with different resolutions generated by the Transformer blocks. The proposed Transformer-based network is named the high-resolution Swin Transformer network (HRSTNet). Extensive experiments demonstrated that the HRSTNet can achieve performance comparable with that of the state-of-the-art Transformer-based U-Net-like architecture on the 2021 Brain Tumor Segmentation dataset, the Medical Segmentation Decathlon's liver dataset, and the BTCV multi-organ segmentation dataset.
    MeSH term(s) Humans ; Brain Neoplasms ; Electric Power Supplies ; Liver ; Masks ; Image Processing, Computer-Assisted
    Language English
    Publishing date 2023-03-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23073420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Investigation of

    Xing, Xiu-Shuang / Zhou, Zhongyuan / Song, Peilin / Song, Xin / Ren, Xiaofei / Zhang, Daojun / Zeng, Xuyang / Guo, Yao / Du, Jimin

    Dalton transactions (Cambridge, England : 2003)

    2023  Volume 52, Issue 35, Page(s) 12308–12317

    Abstract: Surface catalyst engineering can effectively improve the photoelectrochemical water splitting (PEC-WS) performance of semiconductor photoelectrodes. ...

    Abstract Surface catalyst engineering can effectively improve the photoelectrochemical water splitting (PEC-WS) performance of semiconductor photoelectrodes.
    Language English
    Publishing date 2023-09-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt02197a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Correction: Evidence of brain target engagement in Parkinson's disease and multiple sclerosis by the investigational nanomedicine, CNM- Au8, in the REPAIR phase 2 clinical trials.

    Ren, Jimin / Dewey, Richard B / Rynders, Austin / Evan, Jacob / Evan, Jeremy / Ligozio, Shelia / Ho, Karen S / Sguigna, Peter V / Glanzman, Robert / Hotchkin, Michael T / Greenberg, Benjamin M

    Journal of nanobiotechnology

    2024  Volume 22, Issue 1, Page(s) 16

    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2100022-0
    ISSN 1477-3155 ; 1477-3155
    ISSN (online) 1477-3155
    ISSN 1477-3155
    DOI 10.1186/s12951-023-02269-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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