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  1. Article: 'I'm transparent and open'. Interview by Carolyn Ryan.

    Hakesley-Brown, R

    Nursing times

    2000  Volume 96, Issue 43, Page(s) 12–13

    MeSH term(s) Attitude of Health Personnel ; Humans ; Nurse Administrators/psychology ; Organizational Objectives ; Societies, Nursing/organization & administration ; United Kingdom
    Language English
    Publishing date 2000-10
    Publishing country England
    Document type Interview
    ZDB-ID 391202-4
    ISSN 0954-7762 ; 0029-6589
    ISSN 0954-7762 ; 0029-6589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 428: Show issues Location:
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  2. Article ; Online: US states want to buy cheap drugs from Canada-and the FDA says yes after three year delay.

    Brown, Carolyn

    BMJ (Clinical research ed.)

    2024  Volume 384, Page(s) 2983

    Language English
    Publishing date 2024-01-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.p2983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Canada tackles workforce shortages with international fast tracks and federal cash injections.

    Brown, Carolyn

    BMJ (Clinical research ed.)

    2023  Volume 382, Page(s) 1755

    MeSH term(s) Humans ; Workforce ; Canada
    Language English
    Publishing date 2023-08-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.p1755
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: High price and demand for semaglutide means lack of access for US patients.

    Brown, Carolyn

    BMJ (Clinical research ed.)

    2023  Volume 382, Page(s) 1863

    MeSH term(s) Humans ; Patients ; Glucagon-Like Peptides/therapeutic use
    Chemical Substances semaglutide (53AXN4NNHX) ; Glucagon-Like Peptides (62340-29-8)
    Language English
    Publishing date 2023-08-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.p1863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Sickle cell disease: current treatment and emerging therapies

    Neumayr, Lynne D. / Hoppe, Carolyn C. / Brown, Clark

    (The American journal of managed care ; vol. 25, no. 18, sup. (November 2019))

    2019  

    Author's details Atul A. Deodhar, MD
    Series title The American journal of managed care ; vol. 25, no. 18, sup. (November 2019)
    Collection
    Language English
    Size Seite S333-S344, Diagramme
    Publisher Managed Care & Healthcare Communications, LLC
    Publishing place Plainsboro, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT020360073
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs A 5353 -25,18,Suppl.- not available for loan Zeitschriften-Lesesaal

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  6. Article ; Online: Studying CaMKII: Tools and standards.

    Brown, Carolyn Nicole / Bayer, Karl Ulrich

    Cell reports

    2024  Volume 43, Issue 4, Page(s) 113982

    Abstract: ... The ... ...

    Abstract The Ca
    MeSH term(s) Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Humans ; Animals ; Calcium/metabolism
    Chemical Substances Calcium-Calmodulin-Dependent Protein Kinase Type 2 (EC 2.7.11.17) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2024.113982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Scientists are harnessing viruses to treat tumours.

    Brown, Carolyn

    Nature

    2020  Volume 587, Issue 7835, Page(s) S60–S62

    MeSH term(s) Animals ; Bortezomib/pharmacology ; Bortezomib/therapeutic use ; History, 19th Century ; History, 20th Century ; History, 21st Century ; Humans ; Immunotherapy ; Measles virus/immunology ; Multiple Myeloma/diagnosis ; Multiple Myeloma/immunology ; Multiple Myeloma/pathology ; Multiple Myeloma/therapy ; Myxoma virus/immunology ; Oncolytic Virotherapy/history ; Reoviridae/immunology
    Chemical Substances Bortezomib (69G8BD63PP)
    Language English
    Publishing date 2020-11-22
    Publishing country England
    Document type Historical Article ; News
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-020-03226-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 26: Show issues Location:
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    Zs.MG 9: Show issues
    Zs.MO 244: Show issues

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  8. Article ; Online: Stress of first postgraduate year leaves mark at cellular level for medical trainees.

    Brown, Carolyn

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2019  Volume 191, Issue 27, Page(s) E773–E774

    MeSH term(s) Canada ; Humans ; Internship and Residency ; Stress, Psychological/physiopathology ; Telomere Shortening
    Language English
    Publishing date 2019-07-08
    Publishing country Canada
    Document type News
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.109-5770
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.136: Show issues Location:
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  9. Article ; Online: Measles resurgence comes to Canada.

    Brown, Carolyn

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2019  Volume 191, Issue 11, Page(s) E319

    MeSH term(s) Canada/epidemiology ; Disease Outbreaks ; Humans ; Measles/epidemiology ; Measles/prevention & control ; Measles Vaccine ; Vaccination/statistics & numerical data
    Chemical Substances Measles Vaccine
    Language English
    Publishing date 2019-02-27
    Publishing country Canada
    Document type News
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.109-5724
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Acoustically Evoked Compound Action Potentials Recorded From Cochlear Implant Users With Preserved Acoustic Hearing.

    Kim, Jeong-Seo / Brown, Carolyn J

    Ear and hearing

    2023  Volume 44, Issue 5, Page(s) 1061–1077

    Abstract: Objectives: Less traumatic intracochlear electrode design and the introduction of the soft surgery technique allow for the preservation of low-frequency acoustic hearing in many cochlear implant (CI) users. Recently, new electrophysiologic methods have ... ...

    Abstract Objectives: Less traumatic intracochlear electrode design and the introduction of the soft surgery technique allow for the preservation of low-frequency acoustic hearing in many cochlear implant (CI) users. Recently, new electrophysiologic methods have also been developed that allow acoustically evoked peripheral responses to be measured in vivo from an intracochlear electrode. These recordings provide clues to the status of peripheral auditory structures. Unfortunately, responses generated from the auditory nerve (auditory nerve neurophonic [ANN]) are somewhat difficult to record because they are smaller than the hair cell responses (cochlear microphonic). Additionally, it is difficult to completely segregate the ANN from the cochlear microphonic, complicating the interpretation and limiting clinical applications. The compound action potential (CAP) is a synchronous response of multiple auditory nerve fibers and may provide an alternative to ANN where the status of the auditory nerve is of primary interest. This study is a within-subject comparison of CAPs recorded using traditional stimuli (clicks and 500 Hz tone bursts) and a new stimulus (CAP chirp). We hypothesized that the chirp stimulus might result in a more robust CAP than that recorded using traditional stimuli, allowing for a more accurate assessment of the status of the auditory nerve.
    Design: Nineteen adult Nucleus L24 Hybrid CI users with residual low-frequency hearing participated in this study. CAP responses were recorded from the most apical intracochlear electrode using a 100 μs click, 500 Hz tone bursts, and chirp stimuli presented via the insert phone to the implanted ear. The chirp stimulus used in this study was CAP chirp generated using parameters from human-derived band CAPs ( Chertoff et al. 2010 ). Additionally, nine custom chirps were created by systematically varying the frequency sweep rate of the power function used to construct the standard CAP chirp stimulus. CAPs were recorded using all acoustic stimuli, allowing for within-subject comparisons of the CAP amplitude, threshold, percentage of measurable CAP responses, and waveform morphology.
    Results: Considerable variation in response morphology was apparent across stimuli and stimulation levels. Clicks and CAP chirp significantly evoked identifiable CAP response more compared to 500 Hz tone bursts. At relatively high stimulation levels, the chirp-evoked CAPs were significantly larger in amplitude and less ambiguous in morphology than the click-evoked CAPs. The status of residual acoustic hearing at high frequencies influenced the likelihood that a CAP could be reliably recorded. Subjects with better preserved hearing at high frequencies had significantly larger CAP amplitudes when CAP chirp was used. Customizing the chirp stimulus by varying the frequency sweep rates significantly affected the CAP amplitudes; however, pairwise comparisons did not show significant differences between chirps.
    Conclusions: CAPs can be measured more effectively using broadband acoustic stimuli than 500 Hz tone bursts in CI users with residual low-frequency acoustic hearing. The advantage of using CAP chirp stimulus relative to standard clicks is dependent on the extent of preserved acoustic hearing at high frequencies and the stimulus level. The chirp stimulus may present an attractive alternative to standard clicks or tone bursts for this CI population when the goal is to record robust CAP responses.
    MeSH term(s) Adult ; Humans ; Cochlear Implants ; Action Potentials/physiology ; Hearing ; Cochlear Implantation ; Acoustic Stimulation/methods ; Acoustics ; Evoked Potentials, Auditory, Brain Stem/physiology ; Auditory Threshold/physiology
    Language English
    Publishing date 2023-08-17
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 603093-2
    ISSN 1538-4667 ; 0196-0202
    ISSN (online) 1538-4667
    ISSN 0196-0202
    DOI 10.1097/AUD.0000000000001350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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