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  1. Article ; Online: 4 Cases of Aortic Thrombosis in Patients With COVID-19.

    Woehl, Bastien / Lawson, Bree / Jambert, Lucas / Tousch, Jonathan / Ghassani, Afif / Hamade, Amer

    JACC. Case reports

    2020  Volume 2, Issue 9, Page(s) 1397–1401

    Abstract: Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infection between ... ...

    Abstract Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infection between March 26 and April 12, 2020, in Mulhouse, France. (
    Keywords covid19
    Language English
    Publishing date 2020-06-08
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2020.06.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Antiphospholipid antibodies in patients with coronavirus disease 2019 infection hospitalized in conventional unit.

    Hamadé, Amer / Woehl, Bastien / Harzallah, Ines / Talbot, Marjolaine / Tousch, Jonathan / Jambert, Lucas

    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis

    2020  Volume 32, Issue 2, Page(s) 73–79

    Abstract: Antiphospholipid (aPL) antibodies can arise transiently at times of viral diseases. The objective of this work was to evaluate the incidence of aPL antibodies in patients hospitalized in conventional unit for coronavirus disease 2019 (COVID-19) infection ...

    Abstract Antiphospholipid (aPL) antibodies can arise transiently at times of viral diseases. The objective of this work was to evaluate the incidence of aPL antibodies in patients hospitalized in conventional unit for coronavirus disease 2019 (COVID-19) infection and confirmed venous thromboembolic events (VTE) associated with aPL antibodies. 41 patients infected with COVID-19 were tested for aPL antibodies. None had reported history of aPL syndrome. Arterial and venous duplex ultrasound of lower limbs was performed in all patients at Day 0 and Day 5. All patients had antithrombotic-prophylaxis upon admission using lower molecular weight heparin with Enoxaparin. Biological parameters were collected and analyzed. Nine patients (22%) developed VTE and seven (17%) were positive for aPL antibodies of which five had isolated positive lupus anticoagulant. The sixth patient was double aPL positive IgM anticardiolipin (147.8 U/ml) and anti-Beta2 Glyco protein 1 (97.3 U/ml) antibodies. The seventh was triple positive, IgM anticardiolipin 85.6 UI/ml, IgM anti-Beta2 Glyco protein 1 63.0 U/ml and positive lupus anticoagulant. Among the seven patients with aPL antibodies 2 (28.60%) had VTE. However, the incidence of VTE in patients negative for aPL antibodies was also significant as 20.6% (seven of 34). aPL antibodies were significantly associated with the transfer to ICUs of, P = 0.018. Not only the incidence of aPL antibodies was quite significant within our cohort, but also we observed 28.6% of VTE in aPL-positive patients. We strongly recommend routine testing for aPL antibodies in COVID-19 patients and systematic screening with duplex ultrasound search of vascular complications.
    MeSH term(s) Aged ; Aged, 80 and over ; Antibodies, Antiphospholipid/blood ; Anticoagulants/therapeutic use ; COVID-19/blood ; COVID-19/complications ; Enoxaparin/therapeutic use ; Humans ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2/isolation & purification ; Venous Thromboembolism/blood ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/etiology ; COVID-19 Drug Treatment
    Chemical Substances Antibodies, Antiphospholipid ; Anticoagulants ; Enoxaparin
    Language English
    Publishing date 2020-11-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1033551-1
    ISSN 1473-5733 ; 0957-5235
    ISSN (online) 1473-5733
    ISSN 0957-5235
    DOI 10.1097/MBC.0000000000000963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2920: Show issues Location:
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  3. Article ; Online: 4 Cases of Aortic Thrombosis in Patients With COVID-19

    Woehl, Bastien / Lawson, Bree / Jambert, Lucas / Tousch, Jonathan / Ghassani, Afif / Hamade, Amer

    JACC: Case Reports

    2020  Volume 2, Issue 9, Page(s) 1397–1401

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2666-0849
    DOI 10.1016/j.jaccas.2020.06.003
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: The Conundrum of Occult Cancer Screening in Venous Thromboembolism: Lessons from the REMOTEV Registry.

    Cordeanu, Elena-Mihaela / Jambert, Lucas / Tousch, Jonathan / Mirea, Corina / Delatte, Alexandre / Younes, Waël / Woehl, Bastien / Harter, Claire / Frantz, Anne-Sophie / Hamade, Amer / Schini-Kerth, Valérie / Ohlmann, Patrick / Andres, Emmanuel / Stephan, Dominique

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 7

    Abstract: 1) Background and Objectives: Venous thromboembolism (VTE) is strongly associated with cancer, and may be the first event revealing occult neoplasia. Nonetheless, the reasonable extent of the etiological assessment after an unprovoked VTE event remains ... ...

    Abstract (1) Background and Objectives: Venous thromboembolism (VTE) is strongly associated with cancer, and may be the first event revealing occult neoplasia. Nonetheless, the reasonable extent of the etiological assessment after an unprovoked VTE event remains debated. The main objective of this study was to evaluate the incidence of occult neoplasia one year after an episode of VTE, in consecutively hospitalized patients for VTE from the REMOTEV registry. The secondary objectives were to assess the performance of the various tests used for occult cancer screening in a real-life setting and analyze the risk factors associated with the discovery of cancer and the 1-year prognosis. (2) Methods: REMOTEV is a prospective, non-interventional cohort study of patients with acute VTE. Patients included in the registry from 23 October 2013 to 28 July 2018 were analyzed after a follow-up of 12 months. Cancer detection was performed according to local practices and consisted of a limited strategy to which an abdominal ultrasound was added. In the presence of suggestive clinical manifestations, further examinations were performed on an individual basis. (3) Results: A total of 993 patients were included in the study. At 1 year, the incidence of newly diagnosed cancer was low (5.3%). Half of the detected cancers were metastatic at discovery (51%) and had a poor global prognosis (32% of mortality at 1 year). Admission pulmonary CT scans as well as (thoracic)-abdomino-pelvic CT scans (when performed) were responsible for the majority of detected cancers. Age over 65 years and the concomitant presence of an unusual site and lower-limb deep vein thrombosis were the only factors associated with occult neoplasia in this cohort. After 1-year FU, mortality was higher in cancer patients (HR 6.0 (CI 95% 3.5−10.3, p < 0.0001)), and cancer evolution was the leading cause of death in the cancer group. (4) Conclusions: In REMOTEV, VTE-revealed occult cancer prevalence was low, but similar to recent reports and associated with higher age, multiple thrombotic sites and worse prognosis.
    MeSH term(s) Aged ; Cohort Studies ; Early Detection of Cancer ; Humans ; Neoplasms/complications ; Neoplasms/diagnosis ; Neoplasms/epidemiology ; Prospective Studies ; Registries ; Risk Factors ; Venous Thromboembolism/diagnosis ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/etiology
    Language English
    Publishing date 2022-07-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58070913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6270: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Reply to :Aminotransferases disorders associated with venous thromboembolic events in patients infected with COVID-19.

    Hamadé, Amer / Woehl, Bastien / Talbot, Marjolaine / Bensalah, Naouel / Michel, Pierre / Obringer, Golnaz / Lehn-Hogg, Michèle / Buschenrieder, Nathalie / Issa, Mahdi / Tousch, Jonathan / Stephan, Dominique / Jambert, Lucas

    Annals of hepatology

    2021  Volume 23, Page(s) 100334

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Transaminases ; Venous Thromboembolism/diagnosis ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/etiology ; Venous Thrombosis/diagnosis ; Venous Thrombosis/etiology
    Chemical Substances Transaminases (EC 2.6.1.-)
    Language English
    Publishing date 2021-02-20
    Publishing country Mexico
    Document type Letter ; Comment
    ZDB-ID 2188733-0
    ISSN 1665-2681
    ISSN 1665-2681
    DOI 10.1016/j.aohep.2021.100334
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    Zs.A 6221: Show issues Location:
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  6. Article ; Online: Four cases of aortic thrombosis in patients with COVID-19

    Woehl, Bastien / Lawson, Bree / Jambert, Lucas / Tousch, Jonathan / Ghassani, Afif / Hamade, Amer

    JACC Case Rep

    Abstract: Abstract Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. We describe four cases of aortic thrombosis in patients admitted for COVID-19, between the ... ...

    Abstract Abstract Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. We describe four cases of aortic thrombosis in patients admitted for COVID-19, between the 26th of March and the 12th of April 2020, in Mulhouse (France).
    Keywords covid19
    Publisher Elsevier; PMC; WHO
    Document type Article ; Online
    Note WHO #Covidence: #574772
    DOI 10.1016/j.jaccas.2020.06.003
    Database COVID19

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  7. Article: 4 Cases of Aortic Thrombosis in Patients With COVID-19

    Woehl, Bastien / Lawson, Bree / Jambert, Lucas / Tousch, Jonathan / Ghassani, Afif / Hamade, Amer

    JACC: Case Reports

    Abstract: Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infection between ... ...

    Abstract Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infection between March 26 and April 12, 2020, in Mulhouse, France. (Level of Difficulty: Intermediate.)Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications…
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #574772
    Database COVID19

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    Inter-library loan at ZB MED

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  8. Article ; Online: The Conundrum of Occult Cancer Screening in Venous Thromboembolism

    Elena-Mihaela Cordeanu / Lucas Jambert / Jonathan Tousch / Corina Mirea / Alexandre Delatte / Waël Younes / Bastien Woehl / Claire Harter / Anne-Sophie Frantz / Amer Hamade / Valérie Schini-Kerth / Patrick Ohlmann / Emmanuel Andres / Dominique Stephan

    Medicina, Vol 58, Iss 7, p

    Lessons from the REMOTEV Registry

    2022  Volume 913

    Abstract: 1) Background and Objectives : Venous thromboembolism (VTE) is strongly associated with cancer, and may be the first event revealing occult neoplasia. Nonetheless, the reasonable extent of the etiological assessment after an unprovoked VTE event remains ...

    Abstract (1) Background and Objectives : Venous thromboembolism (VTE) is strongly associated with cancer, and may be the first event revealing occult neoplasia. Nonetheless, the reasonable extent of the etiological assessment after an unprovoked VTE event remains debated. The main objective of this study was to evaluate the incidence of occult neoplasia one year after an episode of VTE, in consecutively hospitalized patients for VTE from the REMOTEV registry. The secondary objectives were to assess the performance of the various tests used for occult cancer screening in a real-life setting and analyze the risk factors associated with the discovery of cancer and the 1-year prognosis. (2) Methods : REMOTEV is a prospective, non-interventional cohort study of patients with acute VTE. Patients included in the registry from 23 October 2013 to 28 July 2018 were analyzed after a follow-up of 12 months. Cancer detection was performed according to local practices and consisted of a limited strategy to which an abdominal ultrasound was added. In the presence of suggestive clinical manifestations, further examinations were performed on an individual basis. (3) Results : A total of 993 patients were included in the study. At 1 year, the incidence of newly diagnosed cancer was low (5.3%). Half of the detected cancers were metastatic at discovery (51%) and had a poor global prognosis (32% of mortality at 1 year). Admission pulmonary CT scans as well as (thoracic)-abdomino-pelvic CT scans (when performed) were responsible for the majority of detected cancers. Age over 65 years and the concomitant presence of an unusual site and lower-limb deep vein thrombosis were the only factors associated with occult neoplasia in this cohort. After 1-year FU, mortality was higher in cancer patients (HR 6.0 (CI 95% 3.5–10.3, p < 0.0001)), and cancer evolution was the leading cause of death in the cancer group. (4) Conclusions : In REMOTEV, VTE-revealed occult cancer prevalence was low, but similar to recent reports and associated with higher age, ...
    Keywords occult cancer ; venous thromboembolism ; pulmonary embolism ; screening ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2022-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Withdrawal Notice: Is There a Link between Lung Parenchyma Lesions, BMI, CRP and D-dimer in COVID-19 Patients Who Had Acute Pulmonary Embolism?

    Hamadé, Amer / Jambert, Lucas / Tousch, Jonathan / Feuerstein, Philippe / Hammas, Karima / Degoul, Samuel / Bensalah, Naouel / Michel, Pierre / Lehn-Hogg, Michèle / Obringer, Golnaz / Buschenrieder, Nathalie / Nusbaum, Philippe / Barakat, Nayrouz / Talbot, Marjolaine / Stephan, Dominique / Woehl, Bastien

    Cardiovascular & hematological disorders drug targets

    2021  

    Language English
    Publishing date 2021-08-11
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2244164-5
    ISSN 2212-4063 ; 1871-529X
    ISSN (online) 2212-4063
    ISSN 1871-529X
    DOI 10.2174/1871529X21666210812102024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5610: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  10. Article ; Online: Reply to :Aminotransferases disorders associated with venous thromboembolic events in patients infected with COVID-19

    Amer Hamadé / Bastien Woehl / Marjolaine Talbot / Naouel Bensalah / Pierre Michel / Golnaz Obringer / Michèle Lehn-Hogg / Nathalie Buschenrieder / Mahdi Issa / Jonathan Tousch / Dominique Stephan / Lucas Jambert

    Annals of Hepatology, Vol 23, Iss , Pp 100334- (2021)

    2021  

    Keywords Specialties of internal medicine ; RC581-951
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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