Article ; Online: Contemporary and Emerging MRI Strategies for Assessing Kidney Allograft Complications: Arterial Stenosis and Parenchymal Injury, From the
AJR. American journal of roentgenology
2023 Volume 222, Issue 3, Page(s) e2329418
Abstract: MRI plays an important role in the evaluation of kidney allografts for vascular complications as well as parenchymal insults. Transplant renal artery stenosis, the most common vascular complication of kidney transplant, can be evaluated by MRA using ... ...
Abstract | MRI plays an important role in the evaluation of kidney allografts for vascular complications as well as parenchymal insults. Transplant renal artery stenosis, the most common vascular complication of kidney transplant, can be evaluated by MRA using gadolinium and nongadolinium contrast agents as well as by unenhanced MRA techniques. Parenchymal injury occurs through a variety of pathways, including graft rejection, acute tubular injury, BK polyomavirus infection, drug-induced interstitial nephritis, and pyelonephritis. Investigational MRI techniques have sought to differentiate among these causes of dysfunction as well as to assess the degree of interstitial fibrosis or tubular atrophy (IFTA)-the common end pathway for all of these processes-which is currently evaluated by invasively obtained core biopsies. Some of these MRI sequences have shown promise in not only assessing the cause of parenchymal injury but also assessing IFTA noninvasively. This review describes current clinically used MRI techniques and previews promising investigational MRI techniques for assessing complications of kidney grafts. |
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MeSH term(s) | Humans ; Constriction, Pathologic ; Kidney/pathology ; Fibrosis ; Kidney Diseases/etiology ; Graft Rejection/diagnostic imaging ; Allografts/pathology ; Magnetic Resonance Imaging/adverse effects |
Language | English |
Publishing date | 2023-06-14 |
Publishing country | United States |
Document type | Journal Article ; Review |
ZDB-ID | 82076-3 |
ISSN | 1546-3141 ; 0361-803X ; 0092-5381 |
ISSN (online) | 1546-3141 |
ISSN | 0361-803X ; 0092-5381 |
DOI | 10.2214/AJR.23.29418 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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