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  1. Article ; Online: Urticaria and mimickers of urticaria.

    Fok, Jie Shen / Katelaris, Constance H

    Frontiers in allergy

    2023  Volume 4, Page(s) 1274031

    Abstract: Urticaria is a common skin condition encountered across various specialties in medicine, especially in dermatology and allergy/immunology practice. It has a heterogeneous presentation hence it is unsurprising that many skin conditions may be confused ... ...

    Abstract Urticaria is a common skin condition encountered across various specialties in medicine, especially in dermatology and allergy/immunology practice. It has a heterogeneous presentation hence it is unsurprising that many skin conditions may be confused with urticaria. Urticaria may present as acute or chronic urticaria, the latter can be further categorised into chronic spontaneous and chronic inducible. In this article, we explore, explain, and summarise various skin lesions that are considered mimickers of urticaria, to promote understanding of each of the conditions highlighted, improve recognition, and reduce misdiagnosis.
    Language English
    Publishing date 2023-09-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-6101
    ISSN (online) 2673-6101
    DOI 10.3389/falgy.2023.1274031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Climate Change and Extreme Weather Events in Australia: Impact on Allergic Diseases.

    Katelaris, Constance H

    Immunology and allergy clinics of North America

    2020  Volume 41, Issue 1, Page(s) 53–62

    Abstract: Several climate change-related predictions and observations have been documented for the Australian continent. Extreme weather events such as cycles of severe drought and damaging flooding are occurring with greater frequency and have a severe impact on ... ...

    Abstract Several climate change-related predictions and observations have been documented for the Australian continent. Extreme weather events such as cycles of severe drought and damaging flooding are occurring with greater frequency and have a severe impact on human health. Two specific aspects of climate change affecting allergic and other respiratory disorders are outlined: firstly, the consequences of extreme weather events and secondly, the change in distribution of airborne allergens that results from various climate change factors.
    MeSH term(s) Allergens ; Australia/epidemiology ; Climate Change ; Extreme Weather ; Humans ; Hypersensitivity/epidemiology
    Chemical Substances Allergens
    Language English
    Publishing date 2020-11-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92606-1
    ISSN 1557-8607 ; 0889-8561
    ISSN (online) 1557-8607
    ISSN 0889-8561
    DOI 10.1016/j.iac.2020.09.003
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  3. Article: Self-Management Plans in Patients with Hereditary Angioedema: Strategies, Outcomes and Integration into Clinical Care.

    Katelaris, Constance H

    Journal of asthma and allergy

    2020  Volume 13, Page(s) 153–158

    Abstract: Chronic conditions, whether genetic or acquired, impose a significant burden on health care systems with high utilisation of hospital and emergency department resources. Self-management is increasingly recognised as one of the pillars in models of care ... ...

    Abstract Chronic conditions, whether genetic or acquired, impose a significant burden on health care systems with high utilisation of hospital and emergency department resources. Self-management is increasingly recognised as one of the pillars in models of care for those with long-term medical conditions. Hereditary angioedema (HAE) is a rare genetic disorder inherited in an autosomal dominant fashion. It is characterised by the occurrence of unpredictable attacks of swelling (angioedema) affecting many body parts including subcutaneous tissues, the gut mucosa and the upper airway. For those affected, it is associated with a high burden of illness and poor quality of life as a result of its unpredictability and the threat of asphyxiation from upper airway oedema or severe pain from abdominal involvement. Prompt recognition and appropriate treatment are necessary to avoid the pain and suffering associated with attacks and to manage life-threatening laryngeal swellings that around 50% of HAE patients will experience in their lifetime. Since the early 2000s, a number of very effective, albeit expensive, treatment options have become available, at least in some countries. Utilisation of these options within a written patient self-management plan provides the most satisfactory treatment outcomes and improves patient quality of life. Successful self-management depends on a productive partnership between patient and health care professional, with patient education the cornerstone of a successful outcome. This is a dynamic process, particularly in a condition such as HAE where frequency and severity of attacks may vary given different life circumstances.
    Language English
    Publishing date 2020-04-30
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2494877-9
    ISSN 1178-6965
    ISSN 1178-6965
    DOI 10.2147/JAA.S200900
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Angioedema With Normal Complement Studies: What Do We Know?

    Katelaris, Constance H / Grumach, Anete S / Bork, Konrad

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 8, Page(s) 2309–2314

    Abstract: Angioedema is generally readily recognizable clinically and is characterized by localized nonpitting edema involving subcutaneous, submucosal, or deep dermal tissue caused by increased vascular permeability and extravasation of intravascular fluid. It ... ...

    Abstract Angioedema is generally readily recognizable clinically and is characterized by localized nonpitting edema involving subcutaneous, submucosal, or deep dermal tissue caused by increased vascular permeability and extravasation of intravascular fluid. It can occur via a variety of mechanisms. A number of clinical conditions (masqueraders) are occasionally mistaken for angioedema. Clinical classification of the various angioedema forms begins with noting the presence or absence of concurrent urticaria or wheals. Pathogenesis can be considered through two broad categories: mast cell-mediated with release of vasoactive mediators causing angioedema usually associated with urticaria or in the context of an anaphylactic reaction; and bradykinin (BK)-driven, in which increased vascular permeability is mediated by BK. BK-mediated angioedema does not occur with urticaria, nor does it respond to antiallergic medications. The various forms of hereditary angioedema are included in this category, requiring specific tests of C4 and C1 inhibitor level and function to confirm the diagnosis. Angiotensin converting enzyme inhibitors, which impair the degradation of BK, account for up to a third of all patients with angioedema presenting to the emergency department. Finally, angioedema may occur by yet unknown mechanisms; under this circumstance, it is difficult to manage.
    MeSH term(s) Humans ; Angioedema/drug therapy ; Urticaria/diagnosis ; Urticaria/drug therapy ; Angioedemas, Hereditary/drug therapy ; Complement C1 Inhibitor Protein/therapeutic use ; Bradykinin/therapeutic use ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use
    Chemical Substances Complement C1 Inhibitor Protein ; Bradykinin (S8TIM42R2W) ; Angiotensin-Converting Enzyme Inhibitors
    Language English
    Publishing date 2023-06-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.06.022
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7086: Show issues Location:
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  5. Article ; Online: Acute Management of Hereditary Angioedema Attacks.

    Katelaris, Constance H

    Immunology and allergy clinics of North America

    2017  Volume 37, Issue 3, Page(s) 541–556

    Abstract: Several treatment modalities have become available for management of acute hereditary angioedema (HAE) attacks in the last 15 years. Most are now available to patients in North America, Europe, United Kingdom, and Australia, but few options exist in ... ...

    Abstract Several treatment modalities have become available for management of acute hereditary angioedema (HAE) attacks in the last 15 years. Most are now available to patients in North America, Europe, United Kingdom, and Australia, but few options exist in developing countries. Preferred contemporary use of the treatments to be discussed is "on demand," because control remains with the patient and delays in treatment access avoided. Four treatments-plasma-derived C1 inhibitor concentrate, recombinant C1 inhibitor concentrate, ecallantide, and icatibant-are reviewed in this article. All have been shown to be superior to placebo and effective in the management of all HAE attacks.
    MeSH term(s) Acute Disease ; Angioedemas, Hereditary/diagnosis ; Angioedemas, Hereditary/therapy ; Complement C1 Inhibitor Protein/administration & dosage ; Complement C1 Inhibitor Protein/adverse effects ; Complement C1 Inhibitor Protein/therapeutic use ; Disease Management ; Disease Progression ; Humans ; Recombinant Proteins/administration & dosage ; Recombinant Proteins/adverse effects ; Recombinant Proteins/therapeutic use ; Recurrence ; Treatment Outcome
    Chemical Substances Complement C1 Inhibitor Protein ; Recombinant Proteins ; SERPING1 protein, human ; conestat alfa (5QS67N4551)
    Language English
    Publishing date 2017-05-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92606-1
    ISSN 1557-8607 ; 0889-8561
    ISSN (online) 1557-8607
    ISSN 0889-8561
    DOI 10.1016/j.iac.2017.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: In this issue of Asia Pacific allergy.

    Katelaris, Constance H

    Asia Pacific allergy

    2015  Volume 5, Issue 2, Page(s) 57–58

    Language English
    Publishing date 2015-04-29
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2614800-6
    ISSN 2233-8268 ; 2233-8276
    ISSN (online) 2233-8268
    ISSN 2233-8276
    DOI 10.5415/apallergy.2015.5.2.57
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  7. Article ; Online: Should patients with pollen fruit syndrome be prescribed an automatic epinephrine injector?

    Katelaris, Constance H

    Current opinion in allergy and clinical immunology

    2016  Volume 16, Issue 4, Page(s) 370–374

    Abstract: Purpose of review: The review outlines recent insights into our understanding of the complex relationships between pollen and plant food sensitization patterns resulting in the pollen fruit syndrome and the possible risk, upon ingestion, of generalized ... ...

    Abstract Purpose of review: The review outlines recent insights into our understanding of the complex relationships between pollen and plant food sensitization patterns resulting in the pollen fruit syndrome and the possible risk, upon ingestion, of generalized symptoms rather than localized oropharyngeal reactions. Appreciation of this risk will inform management strategies, which include epinephrine prescription.
    Recent findings: In recent times, the ability to examine molecular components of foods and pollen has allowed further delineation of reactivity patterns. These reveal complex patterns of IgE reactivity and sensitization pathways. More precise definition of these patterns will allow a more accurate analysis of risk of severe food reactions following ingestion.
    Summary: Despite improvement in diagnostic tests, there remains no completely reliable way to determine whether an individual with pollen fruit syndrome is at risk of a systemic reaction. The decision to prescribe an epinephrine autoinjector must be based on a risk assessment for the individual patient.
    MeSH term(s) Allergens/immunology ; Animals ; Disease Management ; Drug Prescriptions ; Epinephrine/therapeutic use ; Fruit/immunology ; Humans ; Hypersensitivity/drug therapy ; Hypersensitivity/epidemiology ; Hypersensitivity/immunology ; Immunoglobulin E/metabolism ; Pollen/immunology ; Risk Assessment ; Syndrome
    Chemical Substances Allergens ; Immunoglobulin E (37341-29-0) ; Epinephrine (YKH834O4BH)
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2088710-3
    ISSN 1473-6322 ; 1528-4050
    ISSN (online) 1473-6322
    ISSN 1528-4050
    DOI 10.1097/ACI.0000000000000278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5666: Show issues Location:
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  8. Article: Rare diseases and expensive drugs.

    Katelaris, Constance H

    Asia Pacific allergy

    2014  Volume 4, Issue 2, Page(s) 73–74

    Language English
    Publishing date 2014-04-29
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2614800-6
    ISSN 2233-8268 ; 2233-8276
    ISSN (online) 2233-8268
    ISSN 2233-8276
    DOI 10.5415/apallergy.2014.4.2.73
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  9. Article ; Online: Angioedema Masqueraders.

    Fok, Jie Shen / Katelaris, Constance H

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

    2019  Volume 49, Issue 10, Page(s) 1274–1282

    Abstract: Angioedema is a common reason for referral to immunology and allergy specialists. Not all cases are in fact angioedema. There are many conditions that may mimic its appearance, resulting in misdiagnosis. This may happen when a clinician is unfamiliar ... ...

    Abstract Angioedema is a common reason for referral to immunology and allergy specialists. Not all cases are in fact angioedema. There are many conditions that may mimic its appearance, resulting in misdiagnosis. This may happen when a clinician is unfamiliar with conditions resembling angioedema or when there is a low index of clinical suspicion. In this article, we explore a list of differential diagnoses based on body parts, including the lips, the limbs, periorbital tissues, the face, epiglottis and uvula, as well as the genitalia, that may pose as a masquerader even to an experienced eye.
    MeSH term(s) Angioedema/diagnosis ; Angioedema/immunology ; Angioedema/pathology ; Diagnosis, Differential ; Humans
    Language English
    Publishing date 2019-08-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 645204-8
    ISSN 1365-2222 ; 0954-7894 ; 0960-2178
    ISSN (online) 1365-2222
    ISSN 0954-7894 ; 0960-2178
    DOI 10.1111/cea.13463
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  10. Article ; Online: Current perspectives on peanut allergy.

    Frith, Katie / Katelaris, Constance H

    Internal medicine journal

    2019  Volume 49, Issue 12, Page(s) 1480–1487

    Abstract: Peanut allergy is increasingly prevalent and for most patients is a life-long condition, with the potential to cause life-threatening reactions. Accurate diagnosis and appropriate management are essential to minimise risks due to accidental peanut ... ...

    Abstract Peanut allergy is increasingly prevalent and for most patients is a life-long condition, with the potential to cause life-threatening reactions. Accurate diagnosis and appropriate management are essential to minimise risks due to accidental peanut exposure. Current management strategies focus on strict allergen avoidance and access to emergency medicines to treat potential reactions; however, active approaches are an area of intense research. Promising new methods of food allergen immunotherapy are set to change the approach to managing peanut allergic patients in the near future.
    MeSH term(s) Anaphylaxis/drug therapy ; Anaphylaxis/etiology ; Anaphylaxis/prevention & control ; Desensitization, Immunologic/methods ; Disease Management ; Humans ; Peanut Hypersensitivity/complications ; Peanut Hypersensitivity/diagnosis ; Peanut Hypersensitivity/therapy
    Language English
    Publishing date 2019-12-20
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 2045436-3
    ISSN 1445-5994 ; 1444-0903
    ISSN (online) 1445-5994
    ISSN 1444-0903
    DOI 10.1111/imj.14658
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    Zs.MO 424: Show issues

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