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  1. Article ; Online: Antifungal susceptibility testing following the CLSI M27 document, along with the measurement of MFC/MIC ratio, could be the optimal approach to detect amphotericin B resistance in

    Sasoni, Natalia / Caracciolo, Beatriz / Cabeza, Matías S / Gamarra, Soledad / Carnovale, Susana / Garcia-Effron, Guillermo

    Antimicrobial agents and chemotherapy

    2023  Volume 68, Issue 1, Page(s) e0096823

    Abstract: Antifungal susceptibility testing (AST) is crucial in clinical settings to guide appropriate therapy. Nevertheless, discrepancies between treatment response and some results still persist, particularly in detecting resistance to amphotericin B (AMB) ... ...

    Abstract Antifungal susceptibility testing (AST) is crucial in clinical settings to guide appropriate therapy. Nevertheless, discrepancies between treatment response and some results still persist, particularly in detecting resistance to amphotericin B (AMB) in
    MeSH term(s) Amphotericin B/pharmacology ; Antifungal Agents/pharmacology ; Antifungal Agents/therapeutic use ; Candida ; Agar/pharmacology ; Echinocandins/pharmacology ; Microbial Sensitivity Tests
    Chemical Substances Amphotericin B (7XU7A7DROE) ; Antifungal Agents ; Agar (9002-18-0) ; Echinocandins
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/aac.00968-23
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 809: Show issues Location:
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  2. Article ; Online: Microscopic and virtual approaches to oral pathology: A case study from El Mirador Cave (Sierra de Atapuerca, Spain).

    Lozano, Marina / Gamarra, Beatriz / Hernando, Raquel / Ceperuelo, Dolors

    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft

    2021  Volume 239, Page(s) 151827

    Abstract: Background: The analysis and diagnosis of ancient oral pathologies have been improved with the application of new techniques such as microscopy and scanning methods over the past few decades. However, the enhancement of the diagnosis implies a prior ... ...

    Abstract Background: The analysis and diagnosis of ancient oral pathologies have been improved with the application of new techniques such as microscopy and scanning methods over the past few decades. However, the enhancement of the diagnosis implies a prior knowledge of the availability and suitability of such equipments.
    Methods: In this work we examined 3D digital and scanning electron microscopy and two computed tomography systems (CBCT and microCT) in order to assess dental and oral disease of the individuals of a Chalcolithic collective burial from El Mirador cave (Sierra de Atapuerca, Spain).
    Results and conclusions: 3D Digital microscopy and CBCT are excellent options to analyze dental pathologies as they are more frequently available, sample preparation is not required, easy to operate, offer excellent images and the possibility of measurements and 3D reconstructions.
    MeSH term(s) Humans ; Spain ; X-Ray Microtomography
    Language English
    Publishing date 2021-09-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1106738-x
    ISSN 1618-0402 ; 0940-9602
    ISSN (online) 1618-0402
    ISSN 0940-9602
    DOI 10.1016/j.aanat.2021.151827
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  3. Article: Relationship between Body Composition and Biochemical Parameters with Antioxidant Status in a Healthy Cohort of Postmenopausal Women.

    Vázquez-Lorente, Héctor / Herrera-Quintana, Lourdes / Molina-López, Jorge / Gamarra-Morales, Yenifer / López-González, Beatriz / Planells, Elena

    Metabolites

    2022  Volume 12, Issue 8

    Abstract: An adequate prooxidant-antioxidant balance-which may be influenced by body composition and biochemical status-is essential to maintain human health, especially in circumstances under which the antioxidant defense decreases, such as menopause. The present ...

    Abstract An adequate prooxidant-antioxidant balance-which may be influenced by body composition and biochemical status-is essential to maintain human health, especially in circumstances under which the antioxidant defense decreases, such as menopause. The present study aimed to examine the relationship between body composition and biochemical parameters with antioxidant status in a healthy cohort of postmenopausal women. This cross-sectional study was carried out in a cohort of 78 postmenopausal women aged 44-76 years. The body composition profile was assessed through bioelectrical impedance. The determination of the total antioxidant capacity and superoxide dismutase activity was conducted by the colorimetric method, and glutathione peroxidase activity was determined by the enzymatic immunological method. The vitamin D levels were measured by ultra-performance liquid chromatography-tandem mass spectrometry. The mineral status was assessed through flame atomic absorption spectrophotometry. The rest of the biochemical parameters were assessed through an immunoassay. The total antioxidant capacity and antioxidant gap were negatively influenced by body composition (all
    Language English
    Publishing date 2022-08-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662251-8
    ISSN 2218-1989
    ISSN 2218-1989
    DOI 10.3390/metabo12080746
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  4. Article ; Online: Erythrocyte Zn concentration and antioxidant response after supplementation with Zn in a postmenopausal population. A double-blind randomized trial.

    Vázquez-Lorente, Héctor / Molina-López, Jorge / Herrera-Quintana, Lourdes / Gamarra-Morales, Yenifer / Quintero-Osso, Bartolomé / López-González, Beatriz / Planells, Elena

    Experimental gerontology

    2022  Volume 162, Page(s) 111766

    Abstract: Background & aims: Menopausal hormonal changes increase the risk of deficiencies of minerals such as zinc (Zn), which could further worsen the decreased antioxidant defense of postmenopausal women. This study assesses the effect of 8 weeks of Zn ... ...

    Abstract Background & aims: Menopausal hormonal changes increase the risk of deficiencies of minerals such as zinc (Zn), which could further worsen the decreased antioxidant defense of postmenopausal women. This study assesses the effect of 8 weeks of Zn supplementation upon the antioxidant status and clinical nutritional parameters of a postmenopausal population.
    Methods: Fifty-one postmenopausal women were divided into two groups: placebo (PbG) and zinc supplementation (ZnG). Mineral status was determined by Flame Atomic Absorption Spectrophotometry (FAAS). Total Antioxidant Capacity (TAC) and Superoxide Dismutase (SOD) were analyzed by kinetic colorimetric methods. Glutathione Peroxidase (GPx) was assessed by an enzymatic immunological method.
    Results: Poor Zn status was initially observed in erythrocyte samples. Total antioxidant capacity showed a significant correlation (r = 0.730; p < 0.05) to erythrocyte Zn after the intervention (ZnG: r = 0.96; p < 0.001). Moreover, erythrocyte Zn concentration in ZnG was positively correlated to GPx activity after the intervention (r = 0.61; p < 0.01).
    Conclusions: The postmenopausal women initially presented Zn deficiency, and the status of this mineral improved after the intervention. Zinc supplementation may be an effective approach for correcting the observed deficiencies, enhancing antioxidant defense in this risk population.
    Clinical trial registration: The present study is registered at the US National Institutes of Health (ClinicalTrials.gov), NCT03672513.
    MeSH term(s) Antioxidants ; Dietary Supplements ; Double-Blind Method ; Erythrocytes ; Female ; Glutathione Peroxidase ; Humans ; Postmenopause ; Superoxide Dismutase ; Zinc
    Chemical Substances Antioxidants ; Glutathione Peroxidase (EC 1.11.1.9) ; Superoxide Dismutase (EC 1.15.1.1) ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2022-03-09
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 390992-x
    ISSN 1873-6815 ; 0531-5565
    ISSN (online) 1873-6815
    ISSN 0531-5565
    DOI 10.1016/j.exger.2022.111766
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 579: Show issues Location:
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  5. Article ; Online: Antibacterial Films Made of Ionic Complexes of Poly(γ-glutamic acid) and Ethyl Lauroyl Arginate.

    Gamarra-Montes, Ana / Missagia, Beatriz / Morató, Jordi / Muñoz-Guerra, Sebastián

    Polymers

    2017  Volume 10, Issue 1

    Abstract: The biocide agent LAE ( ... ...

    Abstract The biocide agent LAE (ethyl
    Language English
    Publishing date 2017-12-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym10010021
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  6. Article ; Online: Effectiveness of eight-week zinc supplementation on vitamin D

    Vázquez-Lorente, Héctor / Molina-López, Jorge / Herrera-Quintana, Lourdes / Gamarra-Morales, Yenifer / López-González, Beatriz / Planells, Elena

    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

    2021  Volume 65, Page(s) 126730

    Abstract: Background: The menopausal period is characterized by hormonal imbalance related to the alteration of parameters involved in lipid metabolism. In addition, menopause increases the risk of deficiencies of key vitamins and minerals such as vitamin D and ... ...

    Abstract Background: The menopausal period is characterized by hormonal imbalance related to the alteration of parameters involved in lipid metabolism. In addition, menopause increases the risk of deficiencies of key vitamins and minerals such as vitamin D and zinc in such women. The present study investigates the influence of zinc supplementation on the status of vitamin D
    Methods: Fifty-one healthy postmenopausal women aged 44-76 years from the province of Granada (Spain) were divided into two groups (placebo and zinc) of 25 and 26 women, respectively. The zinc group was supplemented with 50 mg/day of zinc for 8 weeks. Nutrient intake assessment was performed by means of a 24 -h reminder. Zinc was determined by flame atomic absorption spectrophotometry. Vitamin D was analyzed by liquid chromatography - tandem mass spectrometry. Leptin was determined by enzyme immunoassay.
    Results: Zinc supplementation improved the initial vitamin D
    Conclusion: Zinc supplementation improved vitamin D
    MeSH term(s) Adult ; Aged ; Cholecalciferol/blood ; Dietary Supplements ; Double-Blind Method ; Female ; Humans ; Leptin/blood ; Middle Aged ; Nutrition Assessment ; Postmenopause/blood ; Spain ; Time Factors ; Zinc/administration & dosage ; Zinc/blood ; Zinc/pharmacology
    Chemical Substances Leptin ; Cholecalciferol (1C6V77QF41) ; Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2021-02-12
    Publishing country Germany
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1236267-0
    ISSN 1878-3252 ; 1611-602X ; 0946-672X
    ISSN (online) 1878-3252 ; 1611-602X
    ISSN 0946-672X
    DOI 10.1016/j.jtemb.2021.126730
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    Zs.A 2279: Show issues Location:
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  7. Article: UHPLC-Q/Orbitrap/MS/MS Fingerprinting, Free Radical Scavenging, and Antimicrobial Activity of

    Gómez, Jessica / Simirgiotis, Mario J / Lima, Beatriz / Gamarra-Luques, Carlos / Bórquez, Jorge / Caballero, Duilio / Feresin, Gabriela Egly / Tapia, Alejandro

    Antioxidants (Basel, Switzerland)

    2019  Volume 8, Issue 12

    Abstract: The decoction ... ...

    Abstract The decoction of
    Language English
    Publishing date 2019-11-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox8120593
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  8. Article: El Derecho frente a la pandemia por COVID-19

    Garat, María Paula Risso Ferrand / Martín, Ramos Cabanellas / Beatriz, Valentín Gabriel / Slinger, Leonardo / Costa, Leonardo / Herdt, Cristina / Gamarra, Diego / Guerra, Walter

    Revista de Derecho (Universidad Católica Dámaso A. Larrañaga, Facultad de Derecho)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #819463
    Database COVID19

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  9. Article ; Online: Response of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain.

    Vázquez-Lorente, Héctor / Herrera-Quintana, Lourdes / Molina-López, Jorge / Gamarra-Morales, Yenifer / López-González, Beatriz / Miralles-Adell, Claudia / Planells, Elena

    Nutrients

    2020  Volume 12, Issue 8

    Abstract: Menopause is a stage of hormonal imbalance in women which, in addition to other physiopathological consequences, poses a risk of deficiency of key micronutrients such as magnesium and vitamin D. A study was made of the influence of a magnesium ... ...

    Abstract Menopause is a stage of hormonal imbalance in women which, in addition to other physiopathological consequences, poses a risk of deficiency of key micronutrients such as magnesium and vitamin D. A study was made of the influence of a magnesium intervention upon vitamin D status in a postmenopausal population from the province of Granada (Spain). Fifty-two healthy postmenopausal women between 44-76 years of age were included. Two randomized groups-placebo and magnesium (500 mg/day)-were treated during eight weeks. Nutrient intake was assessed using questionnaires based on 72-h recall. Vitamin D was analyzed by liquid chromatography-tandem mass spectrometry. Baseline vitamin D proved deficient in over 80% of the subjects. The administration of magnesium resulted in significantly increased vitamin D levels in the intervention group versus the controls (
    MeSH term(s) Adult ; Aged ; Diet Surveys ; Dietary Supplements ; Female ; Humans ; Magnesium/administration & dosage ; Middle Aged ; Nutritional Status/drug effects ; Postmenopause ; Spain ; Vitamin D/blood
    Chemical Substances Vitamin D (1406-16-2) ; Magnesium (I38ZP9992A)
    Language English
    Publishing date 2020-07-30
    Publishing country Switzerland
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu12082283
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  10. Article ; Online: Ionic coupling of hyaluronic acid with ethyl N-lauroyl l-arginate (LAE): Structure, properties and biocide activity of complexes.

    Gamarra, Ana / Missagia, Beatriz / Urpí, Lourdes / Morató, Jordi / Muñoz-Guerra, Sebastián

    Carbohydrate polymers

    2018  Volume 197, Page(s) 109–116

    Abstract: ... ...

    Abstract Ethyl
    MeSH term(s) Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Arginine/analogs & derivatives ; Arginine/chemistry ; Arginine/pharmacology ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Hyaluronic Acid/chemistry ; Hyaluronic Acid/pharmacology ; Ions/chemistry ; Ions/pharmacology ; Microbial Sensitivity Tests ; Molecular Structure ; Particle Size
    Chemical Substances Anti-Bacterial Agents ; Ions ; ethyl-N(alpha)-dodecanoyl-L-arginate ; Hyaluronic Acid (9004-61-9) ; Arginine (94ZLA3W45F)
    Language English
    Publishing date 2018-05-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2018.05.057
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