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  1. Article: The long and winding road to computerized physician order entry. Massive, 8-year project to bring CPOE to Thomas Jefferson University Hospital is nearly complete.

    Gottlieb, Jonathan

    Physician executive

    2004  Volume 30, Issue 2, Page(s) 30–35

    MeSH term(s) Attitude of Health Personnel ; Hospitals, University/organization & administration ; Humans ; Organizational Innovation ; Pennsylvania
    Language English
    Publishing date 2004-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1404480-8
    ISSN 0898-2759
    ISSN 0898-2759
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4837: Show issues Location:
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  2. Article ; Online: Oxygen Therapy in Right Heart Failure.

    Gottlieb, Jens / Fühner, Thomas

    Deutsches Arzteblatt international

    2023  Volume 120, Issue 11, Page(s) 191

    MeSH term(s) Humans ; Heart Failure ; Oxygen Inhalation Therapy ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2023-05-23
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2022.0374
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Teaching when time is short: Applying the one-minute preceptor model to the emergency department setting.

    Yang, Thomas / Natesan, Sreeja / Corbo, Samuel / Gottlieb, Michael

    AEM education and training

    2024  Volume 8, Issue 1, Page(s) e10927

    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ISSN 2472-5390
    ISSN (online) 2472-5390
    DOI 10.1002/aet2.10927
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Incomplete Guideline Search.

    Gottlieb, Jens / Worth, Heinrich / Volk, Thomas / Fühner, Thomas

    Deutsches Arzteblatt international

    2022  Volume 119, Issue 25, Page(s) 438

    Language English
    Publishing date 2022-09-30
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2022.0141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: CME. Empfehlungen und Leitlinien. Sauerstoff in der Akuttherapie

    Fühner, Thomas / Gottlieb, Jens

    Hausarzt-Praxis

    2023  Volume 18, Issue 8, Page(s) 7

    Language German
    Document type Article
    ZDB-ID 2229849-6
    ISSN 1661-6197
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6266: Show issues Location:
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  6. Article ; Online: Generalizable pipeline for constructing HIV risk prediction models across electronic health record systems.

    May, Sarah B / Giordano, Thomas P / Gottlieb, Assaf

    Journal of the American Medical Informatics Association : JAMIA

    2023  Volume 31, Issue 3, Page(s) 666–673

    Abstract: Objective: The HIV epidemic remains a significant public health issue in the United States. HIV risk prediction models could be beneficial for reducing HIV transmission by helping clinicians identify patients at high risk for infection and refer them ... ...

    Abstract Objective: The HIV epidemic remains a significant public health issue in the United States. HIV risk prediction models could be beneficial for reducing HIV transmission by helping clinicians identify patients at high risk for infection and refer them for testing. This would facilitate initiation on treatment for those unaware of their status and pre-exposure prophylaxis for those uninfected but at high risk. Existing HIV risk prediction algorithms rely on manual construction of features and are limited in their application across diverse electronic health record systems. Furthermore, the accuracy of these models in predicting HIV in females has thus far been limited.
    Materials and methods: We devised a pipeline for automatic construction of prediction models based on automatic feature engineering to predict HIV risk and tested our pipeline on a local electronic health records system and a national claims data. We also compared the performance of general models to female-specific models.
    Results: Our models obtain similarly good performance on both health record datasets despite difference in represented populations and data availability (AUC = 0.87). Furthermore, our general models obtain good performance on females but are also improved by constructing female-specific models (AUC between 0.81 and 0.86 across datasets).
    Discussion and conclusions: We demonstrated that flexible construction of prediction models performs well on HIV risk prediction across diverse health records systems and perform as well in predicting HIV risk in females, making deployment of such models into existing health care systems tangible.
    MeSH term(s) Humans ; Female ; United States ; Electronic Health Records ; Software ; Algorithms ; Machine Learning ; HIV Infections/prevention & control
    Language English
    Publishing date 2023-11-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1205156-1
    ISSN 1527-974X ; 1067-5027
    ISSN (online) 1527-974X
    ISSN 1067-5027
    DOI 10.1093/jamia/ocad217
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    Zs.A 4128: Show issues Location:
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    Zs.MO 312: Show issues

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  7. Article ; Online: Management and outcome of obstructive airway complications after lung transplantation - a 12-year retrospective cohort study.

    Gottlieb, Jens / Fuehner, Thomas / Zardo, Patrick

    Therapeutic advances in respiratory disease

    2023  Volume 17, Page(s) 17534666231181541

    Abstract: Background: Obstructive airway complications (OACs) represent a significant problem after lung transplantation (LTx). Bilateral OACs after double lung transplantation are infrequently reported.: Objectives: The aim of this study was to investigate ... ...

    Abstract Background: Obstructive airway complications (OACs) represent a significant problem after lung transplantation (LTx). Bilateral OACs after double lung transplantation are infrequently reported.
    Objectives: The aim of this study was to investigate management and outcome of OAC.
    Design: Retrospective single-center cohort study.
    Methods: Adult patients with bilateral LTx performed between 2010 and 2021 were included. Patients with follow-ups of less than 3 months and after heart-lung transplantation were excluded. OAC was defined either as the need for stenting, surgical revision, or balloon dilatation. Outcome parameters included graft survival, graft function, quality of life, and management.
    Results: During the study period, 1,170 patients were included. Hundred thirty-five (11.5%) patients developed OAC. Forty-six (4.4%) patients had significant bilateral OAC. Thirty-seven (80%) bilateral OAC patients were treated by stent insertion; in 34 patients, biodegradable stents were used. The median number of bronchoscopies in bilateral OAC was 26 during the first postoperative year compared with nine in controls (
    Conclusion: Bilateral OACs impose a high burden of disease on patients after lung transplantation and were associated with early and late graft loss. Affected patients' OAC demonstrated reduced graft function and impaired quality of life. Most OACs were managed by bronchoscopy preferably by non-permanent stenting. Surgery including re-do transplantation was used in selected cases.
    MeSH term(s) Adult ; Humans ; Retrospective Studies ; Quality of Life ; Cohort Studies ; Lung Transplantation/adverse effects ; Airway Obstruction/etiology ; Treatment Outcome ; Postoperative Complications/etiology ; Postoperative Complications/therapy
    Language English
    Publishing date 2023-08-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2476459-0
    ISSN 1753-4666 ; 1753-4658
    ISSN (online) 1753-4666
    ISSN 1753-4658
    DOI 10.1177/17534666231181541
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6753: Show issues Location:
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  8. Article ; Online: Oxygen Treatment In Covid-19.

    Gottlieb, Jens / Volk, Thomas / Fühner, Thomas

    Deutsches Arzteblatt international

    2021  Volume 118, Issue 22, Page(s) 375–376

    MeSH term(s) COVID-19 ; Humans ; Oxygen ; Respiration, Artificial ; SARS-CoV-2
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-07-11
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2021.0179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Outcomes and Functional Deterioration in Hospital Admissions with Acute Hypoxemia.

    Simon, Susanne / Gottlieb, Jens / Burchert, Ina / Abu Isneineh, René / Fuehner, Thomas

    Advances in respiratory medicine

    2024  Volume 92, Issue 2, Page(s) 145–155

    Abstract: Background: Many hospitalized patients decline in functional status after discharge, but functional decline in emergency admissions with hypoxemia is unknown. The primary aim of this study was to study functional outcomes as a clinical endpoint in a ... ...

    Abstract Background: Many hospitalized patients decline in functional status after discharge, but functional decline in emergency admissions with hypoxemia is unknown. The primary aim of this study was to study functional outcomes as a clinical endpoint in a cohort of patients with acute hypoxemia.
    Methods: A multicenter prospective observational study was conducted in patients with new-onset hypoxemia emergently admitted to two respiratory departments at a university hospital and an academic teaching hospital. Using the WHO scale, the patients' functional status 4 weeks before admission and at hospital discharge was assessed. The type and duration of oxygen therapy, hospital length of stay and survival and risk of hypercapnic failure were recorded.
    Results: A total of 151 patients with a median age of 74 were included. Two-thirds declined in functional status by at least one grade at discharge. A good functional status (OR 4.849 (95% CI 2.209-10.647)) and progressive cancer (OR 6.079 (1.197-30.881)) were more associated with functional decline. Most patients were treated with conventional oxygen therapy (n = 95, 62%). The rates of in-hospital mortality and need for intubation were both 8%.
    Conclusions: Patients with acute hypoxemia in the emergency room have a poorer functional status after hospital discharge. This decline may be of multifactorial origin.
    MeSH term(s) Humans ; Hospitalization ; Patient Discharge ; Hypoxia/etiology ; Hypoxia/therapy ; Hospitals ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 2893877-X
    ISSN 2543-6031 ; 2451-4934
    ISSN (online) 2543-6031
    ISSN 2451-4934
    DOI 10.3390/arm92020016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Perinatal photoperiod associations with bipolar disorder and depression: A systematic literature review and cross-sectional analysis of the UK Biobank database.

    Lewis, Philip / Gottlieb, John F / Morfeld, Peter / Hellmich, Martin / Erren, Thomas C

    Psychiatry research

    2024  Volume 335, Page(s) 115878

    Abstract: Season-of-birth associations with psychiatric disorders point to environmental (co-)aetiological factors such as natural photoperiod that, if clarified, may allow interventions toward prevention. We systematically reviewed the literature concerning ... ...

    Abstract Season-of-birth associations with psychiatric disorders point to environmental (co-)aetiological factors such as natural photoperiod that, if clarified, may allow interventions toward prevention. We systematically reviewed the literature concerning season-of-birth and bipolar disorder and depression and explored associations between the perinatal natural photoperiod and these outcomes in a cross-sectional analysis of the UK Biobank database. We used mean daily photoperiod and relative photoperiod range (relative to the mean) in the 3rd trimester and, separately, in the first 3 months post birth as metrics. From review, increased risk of depression with late spring birth is compatible with increased odds of probable single episode-, probable recurrent-, and diagnosed depression (OR 2.85 95 %CI 1.6-5.08, OR 2.20 95 %CI 1.57-3.1, and OR 1.48 95 %CI 1.11-1.97, respectively) with increasing 3rd trimester relative photoperiod range for participants who experienced relatively non-extreme daily photoperiods. Risk of bipolar disorder with winter-spring birth contrasted with no consistent patterns of perinatal photoperiod metric associations with bipolar disorder in the UK Biobank. As natural photoperiod varies by both time-of-year and latitude, perinatal natural photoperiods (and a hypothesized mechanism of action via the circadian timing system and/or serotonergic circuitry associated with the dorsal raphe nucleus) may reconcile inconsistencies in season-of-birth associations. Further studies are warranted.
    MeSH term(s) Pregnancy ; Female ; Humans ; Photoperiod ; Bipolar Disorder/epidemiology ; Bipolar Disorder/diagnosis ; Cross-Sectional Studies ; Depression/epidemiology ; UK Biobank ; Biological Specimen Banks ; Seasons
    Language English
    Publishing date 2024-03-26
    Publishing country Ireland
    Document type Systematic Review ; Journal Article
    ZDB-ID 445361-x
    ISSN 1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
    ISSN (online) 1872-7123 ; 1872-7506
    ISSN 0925-4927 ; 0165-1781
    DOI 10.1016/j.psychres.2024.115878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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