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Article ; Online: A 5-year-old boy with miliary and osteoarticular tuberculosis.

Washington, Charles Henry / Oberdorfer, Peninnah

BMJ case reports

2014 Volume 2014

Abstract: Osteoarticular involvement is one manifestation of extrapulmonary tuberculosis (TB). We present a 5-year-old Burmese boy with 10 months of right hip pain and decreased range of motion. The patient also had low-grade fever, cough and decreased appetite. ... ...

Abstract	Osteoarticular involvement is one manifestation of extrapulmonary tuberculosis (TB). We present a 5-year-old Burmese boy with 10 months of right hip pain and decreased range of motion. The patient also had low-grade fever, cough and decreased appetite. The patient was undocumented and had recently moved from Myanmar. He was thin, in moderate distress with bilateral lung rhonchi, mild subcostal retractions, low back pain, right hip tenderness and painful and limited right range of motion. The patient's chest and pelvis radiographs showed a miliary pattern and right acetabulum osteolytic lesions, respectively. He was started on anti-TB medication and cefotaxime. Ofloxacin was added because of the concern of drug-resistant TB. The patient underwent a right hip debridement. His symptoms improved markedly, with improved mobility. TB is a challenging infection to diagnose, which can cause significant delays in management.
MeSH term(s)	Anti-Inflammatory Agents/therapeutic use ; Antitubercular Agents/therapeutic use ; Arthralgia/etiology ; Child, Preschool ; Debridement ; Hip Joint/diagnostic imaging ; Hip Joint/physiopathology ; Hip Joint/surgery ; Humans ; Male ; Prednisolone/therapeutic use ; Radiography ; Range of Motion, Articular ; Tuberculosis, Miliary/diagnostic imaging ; Tuberculosis, Miliary/drug therapy ; Tuberculosis, Multidrug-Resistant/diagnostic imaging ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Osteoarticular/diagnostic imaging ; Tuberculosis, Osteoarticular/drug therapy ; Tuberculosis, Osteoarticular/surgery ; Tuberculosis, Pulmonary/diagnostic imaging ; Tuberculosis, Pulmonary/drug therapy
Chemical Substances	Anti-Inflammatory Agents ; Antitubercular Agents ; Prednisolone (9PHQ9Y1OLM)
Language	English
Publishing date	2014-05-28
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2014-204217
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A 6-year-old boy with fever, rash and severe pneumonia.

Kongthavonsakul, Kritsana / Washington, Charles Henry / Oberdorfer, Peninnah

BMJ case reports

2012 Volume 2012

Abstract: The authors report a 6-year-old boy with fever, rash and cough. He was diagnosed with severe measles pneumonia and admitted to the paediatric intensive care unit with severe dyspnoea 8 days after symptom onset. He received intravenous antibiotics and ... ...

Abstract	The authors report a 6-year-old boy with fever, rash and cough. He was diagnosed with severe measles pneumonia and admitted to the paediatric intensive care unit with severe dyspnoea 8 days after symptom onset. He received intravenous antibiotics and high dose vitamin A. Three days later, he had recovered and was discharged home. He had not been vaccinated for measles, mumps and rubella according to the schedule. This case highlights the need for rapid diagnosis, appropriate treatment and determination of vaccination status of children with measles in order to prevent complications.
MeSH term(s)	Amikacin/therapeutic use ; Amoxicillin-Potassium Clavulanate Combination/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Cefotaxime/therapeutic use ; Child ; Diagnosis, Differential ; Drug Therapy, Combination ; Fever/diagnosis ; Humans ; Male ; Measles/diagnosis ; Measles/drug therapy ; Pneumonia/diagnosis ; Pneumonia/drug therapy ; Pneumonia/microbiology ; Vitamin A/therapeutic use
Chemical Substances	Anti-Bacterial Agents ; Vitamin A (11103-57-4) ; Amoxicillin-Potassium Clavulanate Combination (74469-00-4) ; Amikacin (84319SGC3C) ; Cefotaxime (N2GI8B1GK7)
Language	English
Publishing date	2012-05-11
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr.12.2011.5411
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A 12-day-old male newborn with extensive vesicles and fever.

Kongthavonsakul, Kritsana / Washington, Charles Henry / Pruksachatkun, Chulabhorn / Oberdorfer, Peninnah

BMJ case reports

2012 Volume 2012

Abstract: Neonatal varicella infection is a rare condition since vaccine introduction. The authors report the case of a 12-day-old male who presented with a fever and generalised vesicular eruption. The patient's mother had varicella infection 1 day before ... ...

Abstract	Neonatal varicella infection is a rare condition since vaccine introduction. The authors report the case of a 12-day-old male who presented with a fever and generalised vesicular eruption. The patient's mother had varicella infection 1 day before delivery without treatment. The neonate initially did not receive prophylaxis or treatment. He subsequently was started on intravenous acyclovir and recovered without further complications or sequelae. Prompt diagnosis and treatment for maternal prenatal varicella infection is necessary to prevent infection in the newborn, and healthcare provider awareness to avoid nosocomial transmission.
MeSH term(s)	Acyclovir/therapeutic use ; Adolescent ; Antiviral Agents/therapeutic use ; Chickenpox/diagnosis ; Chickenpox/drug therapy ; Chickenpox/pathology ; Female ; Fever/etiology ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases/diagnosis ; Infant, Newborn, Diseases/drug therapy ; Infant, Newborn, Diseases/pathology ; Infectious Disease Transmission, Vertical ; Male ; Pregnancy ; Pregnancy Complications, Infectious/virology
Chemical Substances	Antiviral Agents ; Acyclovir (X4HES1O11F)
Language	English
Publishing date	2012-01-18
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr.11.2011.5211
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A 9-year-old boy with severe diphtherial infection and cardiac complications.

Washington, Charles Henry / Issaranggoon na ayuthaya, Satja / Makonkawkeyoon, Krit / Oberdorfer, Peninnah

BMJ case reports

2014 Volume 2014

Abstract: The incidence of diphtheria has decreased since the introduction of an effective vaccine. However, in countries with low vaccination rates it has now become a re-emerging disease. Complications from diphtheria commonly include upper airway obstruction ... ...

Abstract	The incidence of diphtheria has decreased since the introduction of an effective vaccine. However, in countries with low vaccination rates it has now become a re-emerging disease. Complications from diphtheria commonly include upper airway obstruction and cardiac complications. We present a 9-year-old boy who was diagnosed with diphtheria. He presented with fever, tonsilar plaques, respiratory failure and an incomplete vaccination history. He was endotracheal intubated and received diphtheria antitoxin and penicillin on the first day of hospitalisation. He developed progressive arrhythmias and fulminant myocarditis despite early identification and treatment with equine antitoxin and antibiotics. After a temporary transvenous pacemaker insertion due to third-degree atrioventricular block and hypotension for 1 week, he developed myocardial perforation from the pacemaker tip resulting in pericardial effusion. The treatment included emergency pericardiocentesis and pacemaker removal. His electrocardiogram showed a junctional rhythm with occasional premature ventricular complexes. He then developed ventricular tachycardia and cardiac arrest and finally died.
MeSH term(s)	Animals ; Anti-Bacterial Agents/therapeutic use ; Antitoxins/therapeutic use ; Arrhythmias, Cardiac/etiology ; Arrhythmias, Cardiac/microbiology ; Arrhythmias, Cardiac/therapy ; Brugada Syndrome ; Cardiac Conduction System Disease ; Child ; Corynebacterium diphtheriae ; Diphtheria/complications ; Diphtheria/drug therapy ; Electrocardiography ; Fatal Outcome ; Heart Arrest/etiology ; Heart Conduction System/abnormalities ; Heart Conduction System/microbiology ; Horses ; Humans ; Hypotension/etiology ; Male ; Myocarditis/etiology ; Myocarditis/microbiology ; Pacemaker, Artificial/adverse effects ; Pericardial Effusion/etiology ; Pericardial Effusion/surgery ; Pericardiocentesis
Chemical Substances	Anti-Bacterial Agents ; Antitoxins
Language	English
Publishing date	2014-11-20
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2014-206085
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Self-Directed Learning

An imperative for education in a complex society

(NWU Self-Directed Learning Series)

2021

Series title	NWU Self-Directed Learning Series
Keywords	Education ; Self-directed learning ; 21st century learning ; technology ; multimodality ; teaching-learning ; curriculum ; education
Language	0\|e
Size	1 electronic resource (352 pages)
Publisher	AOSIS
Publishing place	Durbanville
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021614676
ISBN	9781776341597 ; 1776341597
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

Nepogodiev, Dmitri / C Glasbey, James / Li, Elizabeth / Omar, M Omar / FF Simoes, Joana / EF Abbott, Tom / Alser, Osaid / P Arnaud, Alexis / K Bankhead-Kendall, Brittany / A Breen, Kerry / F Cunha, Miguel / H Davidson, Giana / Di Saverio, Salomone / Gallo, Gaetano / A Griffiths, Ewen / R Gujjuri, Rohan / J Hutchinson, Peter / MA Kaafarani, Haytham / Lederhuber, Hans /

an international cohort study

2020

Abstract: Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and ... ...

Abstract	Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 82·6% (219 of 265) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28-2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65-3·22], p<0·0001), American Society of Anesthesiologists grades 3-5 versus grades 1-2 (2·35 [1·57-3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01-2·39], p=0·046), emergency versus elective surgery (1·67 [1·06-2·63], p=0·026), and major versus minor surgery (1·52 [1·01-2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery.
Keywords	covid19
Subject code	616 ; 610
Language	English
Publishing country	it
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: A reply to Sir Henry Clinton's narrative

Themistocles / Clinton, Henry / Cornwallis, Charles Cornwallis / Sackville, George Germain / Washington, George

wherein his numerous errors are pointed out, and the conduct of Lord Cornwallis fully vindicated from all aspersion: including the whole of the public and secret correspondence between Lord George Germain, Sir Henry Clinton, and His Lordship, as also intercepted letters from General Washington. ; [Two lines of Latin quotation]

1783

Keywords	United States
Language	English
Size	Online-Ressource, 21 cm. (4to)
Publisher	London printed: New-York: re-printed by Sower, Morton, and Horner, no. 62, Water-Street, facing Beekman-Slip. And sold by Messrs. Berry and Rogers, in Hanover-Square
Publishing place	S.l
Document type	Book ; Online
Note	Evans, 18208 ; Microform version available in the Readex Early American Imprints series ; Signed on p. 22: Themistocles
Database	Former special subject collection: coastal and deep sea fishing

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Article ; Online: A 5-year-old boy with miliary and osteoarticular tuberculosis.

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Article ; Online: A 6-year-old boy with fever, rash and severe pneumonia.

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Article ; Online: A 12-day-old male newborn with extensive vesicles and fever.

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Article ; Online: A 9-year-old boy with severe diphtherial infection and cardiac complications.

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Book ; Online: Self-Directed Learning

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Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

Full text online

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Inter-library loan at ZB MED

Book ; Online: A reply to Sir Henry Clinton's narrative

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Inter-library loan at ZB MED