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  1. Article: Clot-in-transit: A ticking time bomb in the heart with serious consequences.

    Igwilo, Rita / Pinsino, Alberto / Aksan, Feyzullah / Kapoor, Sumit

    SAGE open medical case reports

    2023  Volume 11, Page(s) 2050313X231151504

    Abstract: Clot-in-transit is associated with severe pulmonary embolism and higher mortality than acute pulmonary embolism without clot-in-transit. The optimal treatment of clot-in-transit is not established. Multiple treatment options have been described, ... ...

    Abstract Clot-in-transit is associated with severe pulmonary embolism and higher mortality than acute pulmonary embolism without clot-in-transit. The optimal treatment of clot-in-transit is not established. Multiple treatment options have been described, including anticoagulation alone, systemic thrombolysis, surgical embolectomy and endovascular catheter-based therapies. Clot-in-transit can embolize to the pulmonary circulation in a matter of seconds and be immediately fatal. We describe two cases of clot-in-transit which embolized quickly upon Intensivist's evaluation and were associated with serious consequences. Management decisions for clot-in-transit should be emergent and based on multidisciplinary discussion of the pulmonary embolism response team.
    Language English
    Publishing date 2023-02-07
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X231151504
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clot-in-transit

    Rita Igwilo / Alberto Pinsino / Feyzullah Aksan / Sumit Kapoor

    SAGE Open Medical Case Reports, Vol

    A ticking time bomb in the heart with serious consequences

    2023  Volume 11

    Abstract: Clot-in-transit is associated with severe pulmonary embolism and higher mortality than acute pulmonary embolism without clot-in-transit. The optimal treatment of clot-in-transit is not established. Multiple treatment options have been described, ... ...

    Abstract Clot-in-transit is associated with severe pulmonary embolism and higher mortality than acute pulmonary embolism without clot-in-transit. The optimal treatment of clot-in-transit is not established. Multiple treatment options have been described, including anticoagulation alone, systemic thrombolysis, surgical embolectomy and endovascular catheter-based therapies. Clot-in-transit can embolize to the pulmonary circulation in a matter of seconds and be immediately fatal. We describe two cases of clot-in-transit which embolized quickly upon Intensivist’s evaluation and were associated with serious consequences. Management decisions for clot-in-transit should be emergent and based on multidisciplinary discussion of the pulmonary embolism response team.
    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The impact of smartphone applications on bowel preparation, compliance with appointments, cost-effectiveness, and patients' quality of life for the colonoscopy process: A scoping review.

    Aksan, Feyzullah / Tanriverdi, Lokman H / Figueredo, Carlos Jose / Barrera, Layla C / Hasham, Alia / Jariwala, Sunit P

    Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

    2022  Volume 29, Issue 2, Page(s) 71–87

    Abstract: The aim of this scoping review is to evaluate the impact of smartphone application (SPA) technology in patients undergoing elective colonoscopy to measure compliance with appointments, cost-effectiveness, bowel preparation, and quality of life. The ... ...

    Abstract The aim of this scoping review is to evaluate the impact of smartphone application (SPA) technology in patients undergoing elective colonoscopy to measure compliance with appointments, cost-effectiveness, bowel preparation, and quality of life. The scoping review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. Ovid Medline, Web of Science, Science Direct, Scopus, Cochrane Library, and PubMed were screened up to Oct 14, 2020, and bibliographies of the retrieved articles were included. Based on pre-specified inclusion and exclusion criteria, 8 primary studies were included in the final analysis from a total of 3,979 non-duplicate articles. Seven out of eight studies measured the bowel preparation quality. In six of these studies, patients in the smartphone group had a successful bowel preparation when compared with the control arm; on the other hand, one study did not find any differences between groups. Adherence to colonoscopy screening was assessed by one study. Patients in the digital intervention arm were significantly more likely to complete a screening test. Patient satisfaction during the periprocedural period of colonoscopy was assessed by five studies which reported significantly higher patient satisfaction in the intervention arm compared to the control arm. None of the studies measured cost-effectiveness. We came to the conclusion that a well-designed, user-friendly SPA can help and guide patients undergoing colonoscopy through the process of following up on their appointments, adhering to bowel preparation, and better understanding their disease condition. Future trials investigating SPAs should include cost-effectiveness and adherence to appointments as an endpoint.
    MeSH term(s) Humans ; Smartphone ; Cost-Benefit Analysis ; Quality of Life ; Mobile Applications ; Colonoscopy
    Language English
    Publishing date 2022-09-01
    Publishing country India
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2299174-8
    ISSN 1998-4049 ; 1319-3767
    ISSN (online) 1998-4049
    ISSN 1319-3767
    DOI 10.4103/sjg.sjg_207_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A COVID-19 patient with intense burning pain.

    Aksan, Feyzullah / Nelson, Eric Andrew / Swedish, Kristin A

    Journal of neurovirology

    2020  Volume 26, Issue 5, Page(s) 800–801

    Abstract: A woman in her forties with asthma and COPD was admitted to a general medical floor with respiratory symptoms, body aches, and anosmia. Reverse transcription polymerase chain reaction detected severe acute respiratory syndrome coronavirus-2. Admission ... ...

    Abstract A woman in her forties with asthma and COPD was admitted to a general medical floor with respiratory symptoms, body aches, and anosmia. Reverse transcription polymerase chain reaction detected severe acute respiratory syndrome coronavirus-2. Admission labs, including biomarkers of the systemic immunological dysfunction seen in many cases of coronavirus disease 2019 (COVID-19), were within normal ranges. On the second day of admission, she developed neck and back pain that was constant, burning in quality, and exacerbated by light touch and heat. Wearing clothing caused pain and interfered with her sleep. The area was tender to light finger stroke. The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain. However, gabapentin was effective. At follow-up 1 month later, her symptoms were improved and still relieved by gabapentin. Neuropathic pain was seen in over 2% of COVID-19 patients in one observational study. The pain seen in our case was bilateral, involved an area innervated by multiple levels of spinal nerves, and was limited to the back. While it is rare, a significant number of COVID-19 patients are afflicted by neuropathic pain, and our case illustrates that gabapentin may be effective.
    MeSH term(s) Acetaminophen/therapeutic use ; Analgesics/therapeutic use ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/complications ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/drug therapy ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/pathology ; Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome/virology ; Back Pain/complications ; Back Pain/drug therapy ; Back Pain/pathology ; Back Pain/virology ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Female ; Gabapentin/therapeutic use ; Humans ; Middle Aged ; Neck Pain/complications ; Neck Pain/drug therapy ; Neck Pain/pathology ; Neck Pain/virology ; Olfaction Disorders/complications ; Olfaction Disorders/drug therapy ; Olfaction Disorders/pathology ; Olfaction Disorders/virology ; Pain/complications ; Pain/drug therapy ; Pain/pathology ; Pain/virology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Treatment Outcome
    Chemical Substances Analgesics ; Acetaminophen (362O9ITL9D) ; Gabapentin (6CW7F3G59X)
    Keywords covid19
    Language English
    Publishing date 2020-08-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1283265-0
    ISSN 1538-2443 ; 1355-0284
    ISSN (online) 1538-2443
    ISSN 1355-0284
    DOI 10.1007/s13365-020-00887-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A COVID-19 patient with intense burning pain

    Aksan, Feyzullah / Nelson, Eric Andrew / Swedish, Kristin A.

    Journal of NeuroVirology ; ISSN 1355-0284 1538-2443

    2020  

    Keywords Cellular and Molecular Neuroscience ; Virology ; Neurology ; Clinical Neurology ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    DOI 10.1007/s13365-020-00887-4
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: A COVID-19 patient with intense burning pain

    Aksan, Feyzullah / Nelson, Eric Andrew / Swedish, Kristin A

    J Neurovirol

    Abstract: A woman in her forties with asthma and COPD was admitted to a general medical floor with respiratory symptoms, body aches, and anosmia. Reverse transcription polymerase chain reaction detected severe acute respiratory syndrome coronavirus-2. Admission ... ...

    Abstract A woman in her forties with asthma and COPD was admitted to a general medical floor with respiratory symptoms, body aches, and anosmia. Reverse transcription polymerase chain reaction detected severe acute respiratory syndrome coronavirus-2. Admission labs, including biomarkers of the systemic immunological dysfunction seen in many cases of coronavirus disease 2019 (COVID-19), were within normal ranges. On the second day of admission, she developed neck and back pain that was constant, burning in quality, and exacerbated by light touch and heat. Wearing clothing caused pain and interfered with her sleep. The area was tender to light finger stroke. The patient was given acetaminophen, NSAIDs, and opioids with no relief of pain. However, gabapentin was effective. At follow-up 1 month later, her symptoms were improved and still relieved by gabapentin. Neuropathic pain was seen in over 2% of COVID-19 patients in one observational study. The pain seen in our case was bilateral, involved an area innervated by multiple levels of spinal nerves, and was limited to the back. While it is rare, a significant number of COVID-19 patients are afflicted by neuropathic pain, and our case illustrates that gabapentin may be effective.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #708986
    Database COVID19

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