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  1. Article ; Online: Association between sleep apnea and ultrasound-defined liver fibrosis: Results from NHANES 2017 to 2020.

    Zhao, Zhi-Wei / Huang, Wen-Sen / Li, Ling / Chen, Li-Da / Lin, Li / Zeng, Hui-Xue

    Medicine

    2024  Volume 103, Issue 17, Page(s) e37949

    Abstract: Liver fibrosis is a critical factor in the advancement of nonalcoholic fatty liver disease towards cirrhosis. There is limited research exploring the association between obstructive sleep apnea (OSA) and liver fibrosis among community populations. The ... ...

    Abstract Liver fibrosis is a critical factor in the advancement of nonalcoholic fatty liver disease towards cirrhosis. There is limited research exploring the association between obstructive sleep apnea (OSA) and liver fibrosis among community populations. The present study aimed to assess the association between sleep apnea (SA) and liver fibrosis based on the National Health and Nutrition Examination Survey (NHANES). Data were acquired from NHANES survey cycle 2017 to 2020. We assessed liver fibrosis by the median values of liver stiffness measurement (LSM). The diagnosis of SA was based on participants' response to sleep questionnaire. Univariate and multivariate logistic regression were used to validate the association of SA and liver fibrosis. A total of 7615 participants were included in this study. The LSM level of SA group was significantly higher than non-SA group. The proportion of liver fibrosis in SA group was markedly higher than that in non-SA group (14.0% vs 7.3%, P < .001). Univariate logistic analysis showed that SA was positively associated with liver fibrosis (OR = 2.068, 95%CI = 1.715-2.494, P < .001). Further multivariate logistic analysis revealed that SA was independently associated with increased risk of liver fibrosis after adjusting for confounding factors (OR = 1.277, 95%CI = 1.003-1.625, P = .048). The current study demonstrated an independent association between self-reported SA and increased risk of ultrasound-defined liver fibrosis in community-based sample.
    MeSH term(s) Humans ; Male ; Female ; Liver Cirrhosis/epidemiology ; Liver Cirrhosis/diagnostic imaging ; Liver Cirrhosis/complications ; Middle Aged ; Nutrition Surveys ; Ultrasonography ; Adult ; Sleep Apnea Syndromes/epidemiology ; Risk Factors ; Cross-Sectional Studies ; Aged ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/complications
    Language English
    Publishing date 2024-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000037949
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The complete plastome of

    Chen, Li-Da / Wang, Hua-Feng / Hou, De-Jia

    Mitochondrial DNA. Part B, Resources

    2022  Volume 7, Issue 4, Page(s) 705–706

    Abstract: ... Syzygium ... ...

    Abstract Syzygium odoratum
    Language English
    Publishing date 2022-04-25
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2022.2067015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Identification of key genes in chronic intermittent hypoxia-induced lung cancer progression based on transcriptome sequencing.

    Chen, Li-Da / Lin, Li / Chen, Ji-Zhi / Song, Yang / Zhang, Wei-Liang / Li, Huang-Yu / Luo, Jia-Min / Zhang, Xiao-Bin

    BMC cancer

    2024  Volume 24, Issue 1, Page(s) 41

    Abstract: Background: Obstructive sleep apnea (OSA) is associated with increased risk of lung cancer mortality. Nevertheless, little is known about the underlying molecular mechanisms. This research aimed to investigate differentially expressed genes (DEGs) and ... ...

    Abstract Background: Obstructive sleep apnea (OSA) is associated with increased risk of lung cancer mortality. Nevertheless, little is known about the underlying molecular mechanisms. This research aimed to investigate differentially expressed genes (DEGs) and explore their function in Lewis lung carcinoma (LLC)-bearing mice exposed to chronic intermittent hypoxia (CIH) by transcriptome sequencing.
    Methods: Lung cancer tissues in LLC-bearing mice exposed to CIH or normoxia were subjected for transcriptome sequencing to examine DEGs. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses were employed to explore the function of DEGs. To evaluate the prognostic value of DEGs, the Kaplan-Meier survival analysis in combination with Cox proportional hazard model were applied based on The Cancer Genome Atlas.
    Results: A total of 388 genes with 207 up-regulated and 181 down-regulated genes were differentially expressed between the CIH and normoxia control groups. Bioinformatics analysis revealed that the DEGs were related to various signaling pathways such as chemokine signaling pathway, IL-17 signaling pathway, TGF-β signaling pathway, transcriptional misregulation in cancer, natural killer cell mediated cytotoxicity, PPAR signaling pathway. In addition, the DEGs including APOL1, ETFB, KLK8, PPP1R3G, PRL, SPTA1, PLA2G3, PCP4L1, NINJ2, MIR186, and KLRG1 were proven to be significantly correlated with poorer overall survival in lung adenocarcinoma.
    Conclusions: CIH caused a significant change of gene expression profiling in LLC-bearing mice. The DEGs were found to be involved in various physiological and pathological processes and correlated with poorer prognosis in lung cancer.
    MeSH term(s) Animals ; Mice ; Lung Neoplasms/genetics ; Transcriptome ; Neoplastic Processes ; Hypoxia/genetics ; Adenocarcinoma of Lung ; Carcinoma, Lewis Lung
    Language English
    Publishing date 2024-01-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-023-11785-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Association of different obesity patterns with hypertension in US male adults: a cross-sectional study.

    Chen, Lu / Zhang, Jun / Zhou, Nan / Weng, Jia-Yi / Bao, Zheng-Yang / Wu, Li-Da

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 10551

    Abstract: Obesity is an important risk factor for hypertension. We aimed to investigate the association between different obesity patterns and hypertension risk in a large male population in the US. Male participants from the National Health and Nutrition ... ...

    Abstract Obesity is an important risk factor for hypertension. We aimed to investigate the association between different obesity patterns and hypertension risk in a large male population in the US. Male participants from the National Health and Nutrition Examination Survey (NHANES) (2007-2018) were enrolled in this cross-sectional study. Social demographic information, lifestyle factors, anthropometric measurements and biochemical measurements were collected. Three obesity patterns were classified according to the body mass index (BMI) and waist circumference (WC), including overweight and general obesity, abdominal obesity, and compound obesity. We adopted multivariate logistic regression to investigate the associations between hypertension and different obesity patterns after adjusting for cofounding factors. Subgroup analysis, stratified by age, smoking, drinking and estimated glomerular filtration rate (eGFR), was also conducted to explore the associations between obesity patterns and hypertension risk among different populations. Moreover, the association between WC and hypertension among male individuals was also explored using restricted cubic spline (RCS) analysis. Receiver operating characteristic (ROC) was used to evaluate the discriminatory power of WC for screening hypertension risk. 13,859 male participants from NHANES survey (2007-2018) were enrolled. Comparing with the normal-weight group, the odds ratios (ORs) [95% confidence interval (CI)] for hypertension in individuals with overweight and general obesity, abdominal obesity and compound obesity were 1.41 [1.17-1.70], 1.97 [1.53-2.54] and 3.28 [2.70-3.99], respectively. Subgroup analysis showed that the effect of different obesity patterns on hypertension risk was highly stable among individuals with different clinical conditions. In addition, WC had a positive correlation with the risk of hypertension (OR: 1.43; 95% CI 1.37-1.52; P < 0.001) in fully adjusted multivariate logistic regression model. RCS analysis showed that the association between WC and hypertension risk was in a nonlinear pattern, and WC had a good discriminatory power for hypertension in ROC analysis. Different patterns of obesity have a great impact on the risk of hypertension among male individuals. Increment of WC significantly increased the hypertension risk. More attention should be paid to the prevention of obesity, especially abdominal obesity and compound obesity in male individuals.
    MeSH term(s) Humans ; Adult ; Male ; Overweight ; Cross-Sectional Studies ; Obesity, Abdominal/complications ; Obesity, Abdominal/epidemiology ; Nutrition Surveys ; Obesity/complications ; Obesity/epidemiology ; Hypertension/epidemiology
    Language English
    Publishing date 2023-06-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-37302-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Electrochemical Detection of Electrolytes Using a Solid-State Ion-Selective Electrode of Single-Piece Type Membrane.

    Chen, Li-Da / Wang, Wei-Jhen / Wang, Gou-Jen

    Biosensors

    2021  Volume 11, Issue 4

    Abstract: This study aimed to develop simple electrochemical electrodes for the fast detection of chloride, sodium and potassium ions in human serum. A flat thin-film gold electrode was used as the detection electrode for chloride ions; a single-piece type ... ...

    Abstract This study aimed to develop simple electrochemical electrodes for the fast detection of chloride, sodium and potassium ions in human serum. A flat thin-film gold electrode was used as the detection electrode for chloride ions; a single-piece type membrane based solid-state ion-selective electrode (ISE), which was formed by covering a flat thin-film gold electrode with a mixture of 7,7,8,8-tetracyanoquinodimethane (TCNQ) and ion-selective membrane (ISM), was developed for sodium and potassium ions detection. Through cyclic voltammetry (CV) and square-wave voltammetry (SWV), the detection data can be obtained within two minutes. The linear detection ranges in the standard samples of chloride, sodium, and potassium ions were 25-200 mM, 50-200 mM, and 2-10 mM, with the average relative standard deviation (RSD) of 0.79%, 1.65%, and 0.47% and the average recovery rates of 101%, 100% and 96%, respectively. Interference experiments with Na
    MeSH term(s) Electrochemical Techniques ; Electrodes ; Electrolytes/analysis ; Gold ; Humans ; Ion-Selective Electrodes ; Ions ; Potassium
    Chemical Substances Electrolytes ; Ions ; Gold (7440-57-5) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2021-04-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios11040109
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Estimated Pulse Wave Velocity Predicts All-Cause and Cardiovascular-Cause Mortality in Individuals With Hypertension - Findings From a National Health and Nutrition Examination Study 1999-2018.

    Shi, Yi / Wu, Li-Da / Feng, Xiao-Hua / Kan, Jun-Yan / Kong, Chao-Hua / Ling, Zhi-Yu / Zhang, Jun-Xia / Chen, Shao-Liang

    Circulation journal : official journal of the Japanese Circulation Society

    2024  Volume 88, Issue 3, Page(s) 417–424

    Abstract: Background: This study aimed to investigate the association between estimated pulse wave velocity (ePWV) and mortality outcomes among individuals with hypertension.Methods and Results: Based on the National Health and Nutrition Examination Survey ( ... ...

    Abstract Background: This study aimed to investigate the association between estimated pulse wave velocity (ePWV) and mortality outcomes among individuals with hypertension.Methods and Results: Based on the National Health and Nutrition Examination Survey (NHANES) 1999-2018, a total of 14,396 eligible participants with hypertension were enrolled. The ePWV was calculated using the equation based on blood pressure and age. The mortality outcomes of included participants were directly acquired from the National Death Index database. The multivariable Cox regression analysis was used to examine the relationship between ePWV and mortality outcomes. Moreover, the restricted cubic spline (RCS) was also used to explore this relationship. Receiver operating characteristics curves (ROC) were adopted to evaluate the prognostic ability of ePWV for predicting mortality outcomes of patients with hypertension. The median follow-up duration was 10.8 years; individuals with higher an ePWV had higher risks of mortality from both all causes (HR: 2.79, 95% CI: 2.43-3.20) and cardiovascular diseases (HR: 3.41, 95% CI: 2.50-4.64). After adjusting for confounding factors, each 1 m/s increase in ePWV was associated with a 43% increase in all-cause mortality risk (HR: 1.43, 95% CI: 1.37-1.48) and a 54% increase in cardiovascular mortality risk (HR: 1.54, 95% CI: 1.43-1.66).
    Conclusions: This study indicates that ePWV is a novel prognostic indicator for predicting the risks of mortality among patients with hypertension.
    MeSH term(s) Humans ; Nutrition Surveys ; Pulse Wave Analysis ; Cardiovascular System ; Hypertension ; Cardiovascular Diseases
    Language English
    Publishing date 2024-01-23
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2068090-9
    ISSN 1347-4820 ; 1346-9843
    ISSN (online) 1347-4820
    ISSN 1346-9843
    DOI 10.1253/circj.CJ-23-0674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: First Report of Leaf Spot on water convolvulus Caused by Stemphylium solani in Yunnan Province, China.

    Chen, Li-Da / Xie, Xuewen / Shi, Yanxia / Chai, A Li / Li, Lei / Li, Baoju

    Plant disease

    2022  

    Abstract: Water convolvulus (Ipomoea aquatica Forsk.), a member of the Convolvulaceae family, is an important tropical vegetable cultivated in China (Liu et al. 2017). From 2016 to 2020, dark-brown leaf spots were observed in major water convolvulus (cv. Large ... ...

    Abstract Water convolvulus (Ipomoea aquatica Forsk.), a member of the Convolvulaceae family, is an important tropical vegetable cultivated in China (Liu et al. 2017). From 2016 to 2020, dark-brown leaf spots were observed in major water convolvulus (cv. Large leaf) growing areas (2 ha) in Honghe City (24°12' N, 103°6' E), Yunnan Province, China. Field investigations showed that a leaf spot disease occurred on water convolvulus in four fields with 15% incidence (50 plants in each field were investigated) and resulted in up to a 10% decrease in its total production. Symptoms on water convolvulus plants appeared as small lesions, yellowish-green and circular on the leaves. Ten plants were selected randomly from the growing area, with three diseased leaves collected from each plant. Symptomatic tissues were excised, surface sterilized with 75% ethanol for 30 s, washed in sterile-distilled water three times, and placed on the Potato Dextrose Agar (PDA) followed by incubation at 25°C in the dark for 7 days. Colonies on PDA were gray to green in color and fuzzy in the middle, with irregular borders. Conidiophore morphology showed single, yellowish-brown or brown structures with 1~6 septa, and long 22~125 µm, wide 3.5~5.5 µm. Conidia were elliptical, black-brow, solitary, with a smooth surface, 1~6 longitudinal septa and 1~3 transverse septa, 20~30 µm in length, and 15~22 µm in width. The morphological characteristics of the fungus were consistent with the description of Stemphylium solani (Chai et al. 2014; Weber, 1930). To further confirm the identity of the 30 isolates, the partial gapdh (glyceraldehyde-3-phosphate dehydrogenase), tef1 (translation elongation factor 1-alpha), cmdA (Calmodulin) and ITS (intemal transcribed spacers) sequences were amplified by PCR with the primer pairs of gpd1/gpd2, EF1-728F/EF1-986R, CALDF1/CALDR2 and ITS1/ITS4, respectively (Berbee et al. 1999; Carbone & Kohn. 1999; Lawrence et al. 2013; White et al. 1990). Multiple sequence alignments were generated using MEGA7, and phylogenetic analysis was conducted with the neighbor-joining (NJ) method (Tamura et al. 2007), the results indicated that all sequences from the 30 isolates were identical. Thus, one representative isolate, KXC11033003 was chosen for further analysis. The ITS, gapdh, cmdA and tef1 sequences of this isolate were submitted to the NCBI GenBank database (accession nos. OL444947~OL444950). The strain KXC11033003 and S. solani (CBS-408.54) formed a clade with 82% bootstrap value (Figure S2). To fulfill Koch's postulates, 30 plants were inoculated for each of the thirty isolates. Conidia were sprayed on leaves of water convolvulus (8-true-leaf stage) in a suspension of 107 conidia/mL or water as a healthy control in a greenhouse at 15~18℃ (night) / 25~28℃ (day) with 95% humidity. Symptoms of dark brown spots appeared on the leaves after 7 days, whereas controls remained healthy The pathogens were reisolated from the lesions and confirmed identical to the original isolate by gene sequences. No pathogens were isolated from the control plants. To our knowledge, this is the first report of leaf spot caused by S. solani on water convolvulus in Yunnan Province, China. Further, Stemphylium leaf spot caused by S. solani has been reported previously on tomato, garlic, pepper (Zheng et al.2008; Nasehi et al.2018). This study stresses the need to identify appropriate management strategies for S. solani that help prevent quality and yield losses in water convolvulus in China.
    Language English
    Publishing date 2022-08-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 754182-x
    ISSN 0191-2917
    ISSN 0191-2917
    DOI 10.1094/PDIS-03-22-0689-PDN
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Analysis of potential genetic biomarkers using machine learning methods and immune infiltration regulatory mechanisms underlying atrial fibrillation.

    Wu, Li-Da / Li, Feng / Chen, Jia-Yi / Zhang, Jie / Qian, Ling-Ling / Wang, Ru-Xing

    BMC medical genomics

    2022  Volume 15, Issue 1, Page(s) 64

    Abstract: Objective: We aimed to screen out biomarkers for atrial fibrillation (AF) based on machine learning methods and evaluate the degree of immune infiltration in AF patients in detail.: Methods: Two datasets (GSE41177 and GSE79768) related to AF were ... ...

    Abstract Objective: We aimed to screen out biomarkers for atrial fibrillation (AF) based on machine learning methods and evaluate the degree of immune infiltration in AF patients in detail.
    Methods: Two datasets (GSE41177 and GSE79768) related to AF were downloaded from Gene expression omnibus (GEO) database and merged for further analysis. Differentially expressed genes (DEGs) were screened out using "limma" package in R software. Candidate biomarkers for AF were identified using machine learning methods of the LASSO regression algorithm and SVM-RFE algorithm. Receiver operating characteristic (ROC) curve was employed to assess the diagnostic effectiveness of biomarkers, which was further validated in another independent validation dataset of GSE14975. Moreover, we used CIBERSORT to study the proportion of infiltrating immune cells in each sample, and the Spearman method was used to explore the correlation between biomarkers and immune cells.
    Results: 129 DEGs were identified, and CYBB, CXCR2, and S100A4 were identified as key biomarkers of AF using LASSO regression and SVM-RFE algorithm. Both in the training dataset and the validation dataset, CYBB, CXCR2, and S100A4 showed favorable diagnostic effectiveness. Immune infiltration analysis indicated that, compared with sinus rhythm (SR), the atrial samples of patients with AF contained a higher T cells gamma delta, neutrophils and mast cells resting, whereas T cells follicular helper were relatively lower. Correlation analysis demonstrated that CYBB, CXCR2, and S100A4 were significantly correlated with the infiltrating immune cells.
    Conclusions: In conclusion, this study suggested that CYBB, CXCR2, and S100A4 are key biomarkers of AF correlated with infiltrating immune cells, and infiltrating immune cells play pivotal roles in AF.
    MeSH term(s) Algorithms ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/genetics ; Atrial Fibrillation/metabolism ; Biomarkers/metabolism ; Genetic Markers ; Heart Atria/metabolism ; Humans ; Machine Learning
    Chemical Substances Biomarkers ; Genetic Markers
    Language English
    Publishing date 2022-03-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2411865-5
    ISSN 1755-8794 ; 1755-8794
    ISSN (online) 1755-8794
    ISSN 1755-8794
    DOI 10.1186/s12920-022-01212-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Association of different obesity patterns with hypertension in US male adults

    Lu Chen / Jun Zhang / Nan Zhou / Jia-Yi Weng / Zheng-Yang Bao / Li-Da Wu

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    a cross-sectional study

    2023  Volume 10

    Abstract: Abstract Obesity is an important risk factor for hypertension. We aimed to investigate the association between different obesity patterns and hypertension risk in a large male population in the US. Male participants from the National Health and Nutrition ...

    Abstract Abstract Obesity is an important risk factor for hypertension. We aimed to investigate the association between different obesity patterns and hypertension risk in a large male population in the US. Male participants from the National Health and Nutrition Examination Survey (NHANES) (2007–2018) were enrolled in this cross-sectional study. Social demographic information, lifestyle factors, anthropometric measurements and biochemical measurements were collected. Three obesity patterns were classified according to the body mass index (BMI) and waist circumference (WC), including overweight and general obesity, abdominal obesity, and compound obesity. We adopted multivariate logistic regression to investigate the associations between hypertension and different obesity patterns after adjusting for cofounding factors. Subgroup analysis, stratified by age, smoking, drinking and estimated glomerular filtration rate (eGFR), was also conducted to explore the associations between obesity patterns and hypertension risk among different populations. Moreover, the association between WC and hypertension among male individuals was also explored using restricted cubic spline (RCS) analysis. Receiver operating characteristic (ROC) was used to evaluate the discriminatory power of WC for screening hypertension risk. 13,859 male participants from NHANES survey (2007–2018) were enrolled. Comparing with the normal-weight group, the odds ratios (ORs) [95% confidence interval (CI)] for hypertension in individuals with overweight and general obesity, abdominal obesity and compound obesity were 1.41 [1.17–1.70], 1.97 [1.53–2.54] and 3.28 [2.70–3.99], respectively. Subgroup analysis showed that the effect of different obesity patterns on hypertension risk was highly stable among individuals with different clinical conditions. In addition, WC had a positive correlation with the risk of hypertension (OR: 1.43; 95% CI 1.37–1.52; P < 0.001) in fully adjusted multivariate logistic regression model. RCS analysis showed that the association ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 796
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Electrochemical Properties of Ti/SnO₂-Sb-Ir Electrodes Doped with a Low Iridium Content for the Oxygen Evolution Reaction in an Acidic Environment

    Wu, Fei / Yang, Zheng-Qing / Sun, Wen / Chen, Xu / Qi, Hui / Wang, Li-Da

    Industrial & engineering chemistry process design and development. 2022 Aug. 09, v. 61, no. 34

    2022  

    Abstract: Ti/SnO₂-Sb-Ir electrodes doped with a low Ir content were prepared, and they were used in acidic water electrolysis for the oxygen evolution reaction (OER). The results showed that an IrO₂–SnO₂ solid solution was formed, and the electrode surface was ... ...

    Abstract Ti/SnO₂-Sb-Ir electrodes doped with a low Ir content were prepared, and they were used in acidic water electrolysis for the oxygen evolution reaction (OER). The results showed that an IrO₂–SnO₂ solid solution was formed, and the electrode surface was relatively compact. The doping of IrO₂ could significantly improve the electrocatalytic activity and stability of Ti/SnO₂-Sb electrode for OER. The electrode modified with only 5 mol % Ir met the needs of acidic water electrolysis. Meanwhile, the performances of the electrode approached that of Ti/IrO₂ when Ir content was only 8 mol %, which resulted from the fact that IrO₂ doping improved the chemical stability as well as the electrocatalytic activity of the electrode. Moreover, the deactivation behavior of the electrode was investigated as well. It was mainly ascribed to the chemical composition and morphology change induced by continuous dissolution of the metal oxides, which eventually led to the passivation of the Ti substrate.
    Keywords chemical composition ; electrochemistry ; electrodes ; electrolysis ; iridium ; oxygen production ; process design
    Language English
    Dates of publication 2022-0809
    Size p. 12349-12358.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 1484436-9
    ISSN 1520-5045 ; 0888-5885
    ISSN (online) 1520-5045
    ISSN 0888-5885
    DOI 10.1021/acs.iecr.2c01012
    Database NAL-Catalogue (AGRICOLA)

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