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  1. Article ; Online: Recreational Runners Gain Physiological and Biomechanical Benefits From Super Shoes at Marathon Paces.

    Paradisis, Giorgos P / Zacharogiannis, Elias / Bissas, Athanassios / Hanley, Brian

    International journal of sports physiology and performance

    2023  Volume 18, Issue 12, Page(s) 1420–1426

    Abstract: ... with an interaction between shoes and speed (P = .020) meaning an increased difference of 5.0% at 80% vVO2peak. There ... were small increases in vertical and leg stiffnesses in the Endorphin shoes (P < .001); the Endorphin ... flight time (P < .001).: Conclusions: There was a physiological benefit to running in the super shoes ...

    Abstract Purpose: Advanced footwear technology is prevalent in distance running, with research focusing on these "super shoes" in competitive athletes, with less understanding of their value for slower runners. The aim of this study was to compare physiological and biomechanical variables between a model of super shoes (Saucony Endorphin Speed 2) and regular running shoes (Saucony Cohesion 13) in recreational athletes.
    Methods: We measured peak oxygen uptake (VO2peak) in 10 runners before testing each subject 4 times in a randomly ordered crossover design (ie, Endorphin shoe or Cohesion shoe, running at 65% or 80% of velocity at VO2peak [vVO2peak]). We recorded video data using a high-speed camera (300 Hz) to calculate vertical and leg stiffnesses.
    Results: 65% vVO2peak was equivalent to a speed of 9.4 km·h-1 (0.4), whereas 80% vVO2peak was equivalent to 11.5 km·h-1 (0.5). Two-way mixed-design analysis of variance showed that oxygen consumption in the Endorphin shoe was 3.9% lower than in the Cohesion shoe at 65% vVO2peak, with an interaction between shoes and speed (P = .020) meaning an increased difference of 5.0% at 80% vVO2peak. There were small increases in vertical and leg stiffnesses in the Endorphin shoes (P < .001); the Endorphin shoe condition also showed trivial to moderate differences in step length, step rate, contact time, and flight time (P < .001).
    Conclusions: There was a physiological benefit to running in the super shoes even at the slower speed. There were also spatiotemporal and global stiffness improvements indicating that recreational runners benefit from wearing super shoes.
    MeSH term(s) Humans ; Biomechanical Phenomena ; Endorphins ; Marathon Running ; Running/physiology ; Shoes ; Cross-Over Studies
    Chemical Substances Endorphins
    Language English
    Publishing date 2023-09-21
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ISSN 1555-0273
    ISSN (online) 1555-0273
    DOI 10.1123/ijspp.2023-0115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Exploring the Irish general practice training community's perceptions on how an entrustable professional activities dashboard implementation could facilitate general practice training in Ireland.

    McEllistrem, Brian / Hennus, Marije P / Fawns, Tim / Hanley, Karena

    Education for primary care : an official publication of the Association of Course Organisers, National Association of GP Tutors, World Organisation of Family Doctors

    2023  Volume 34, Issue 2, Page(s) 91–99

    Abstract: Background: The Irish General Practitioner Training (GP) Programme is currently moving to Competency-Based Medical Education (CBME), facilitated by Programmatic Assessment (PA) and Entrustable Professional Activities (EPAs). These new assessment and ... ...

    Abstract Background: The Irish General Practitioner Training (GP) Programme is currently moving to Competency-Based Medical Education (CBME), facilitated by Programmatic Assessment (PA) and Entrustable Professional Activities (EPAs). These new assessment and feedback mechanisms may provide a rich and much sought-after dataset. However, given the possible number of feedback and assessment events, and the variety of modalities used, aggregating and interpreting these can be costly and difficult. Dashboard implementations (DI) have been purposed as a solution to bridge the gap between the large datasets and the training community at all levels.
    Aims: To explore the Irish GP training community's perceptions on how an EPAs DI could facilitate the delivery of GP training in Ireland.
    Methods: A qualitative approach was taken, using a focus group representative of different groups in the training community. Concurrently, an EPAs DI was developed. Focus group transcripts were analysed in an iterative fashion using Template Analysis to generate themes and subthemes.
    Results: Numerous advantages were seen in relation to the implementation of an EPAs DI around entrustment decisions, constructive alignment and summative decision-making. These advantages, however, need to be tempered with the realisation that the EPAs DI is not and should not be misinterpreted as being the learning analytic panacea for GP training.
    Conclusion: This paper outlines the perceptions from a postgraduate medical education training community on an EPAs DI, which would be applicable to other training communities considering introducing similar mechanisms.
    MeSH term(s) Humans ; Ireland ; Competency-Based Education ; Curriculum ; Focus Groups ; Clinical Competence ; General Practice ; Internship and Residency
    Language English
    Publishing date 2023-03-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2074818-8
    ISSN 1475-990X ; 1473-9879
    ISSN (online) 1475-990X
    ISSN 1473-9879
    DOI 10.1080/14739879.2023.2191340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Results of a 5-Year N-of-1 Growth Hormone Releasing Hormone Gene Therapy Experiment.

    Hanley, Brian P / Brewer, Keith / Church, George

    Rejuvenation research

    2021  Volume 24, Issue 6, Page(s) 424–433

    Abstract: Here presented for the first time are results showing persistence over a 5+ year period in a human who had a hormone gene therapy administered to muscle. This growth hormone releasing hormone (GHRH) therapy was administered in two doses, a year apart, ... ...

    Abstract Here presented for the first time are results showing persistence over a 5+ year period in a human who had a hormone gene therapy administered to muscle. This growth hormone releasing hormone (GHRH) therapy was administered in two doses, a year apart, with a mean after the second dose of 195 ng/mL (13 × normal, σ = 143, σ
    MeSH term(s) Genetic Therapy ; Growth Hormone-Releasing Hormone/administration & dosage ; Humans ; Testosterone
    Chemical Substances Testosterone (3XMK78S47O) ; Growth Hormone-Releasing Hormone (9034-39-3)
    Language English
    Publishing date 2021-11-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2150779-X
    ISSN 1557-8577 ; 1549-1684
    ISSN (online) 1557-8577
    ISSN 1549-1684
    DOI 10.1089/rej.2021.0036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A Call for a Three-Tiered Pandemic Public Health Strategy in Context of SARS-CoV-2.

    Hanley, Brian P / Keen, Steve / Church, George

    Rejuvenation research

    2020  Volume 23, Issue 4, Page(s) 281–283

    MeSH term(s) Betacoronavirus/physiology ; COVID-19 ; COVID-19 Vaccines ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/virology ; Gross Domestic Product ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Pneumonia, Viral/virology ; Public Health ; Risk Assessment ; Risk Factors ; SARS-CoV-2 ; Viral Vaccines/immunology
    Chemical Substances COVID-19 Vaccines ; Viral Vaccines
    Keywords covid19
    Language English
    Publishing date 2020-06-24
    Publishing country United States
    Document type Editorial
    ZDB-ID 2150779-X
    ISSN 1557-8577 ; 1549-1684
    ISSN (online) 1557-8577
    ISSN 1549-1684
    DOI 10.1089/rej.2020.2363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Kinematics of the Final Approach and Take-Off Phases in World-Class Men and Women Pole Vaulters.

    Hanley, Brian / Gravestock, Helen J / Hopkinson, Mike / Paradisis, Giorgos P / Merlino, Stéphane / Bissas, Athanassios

    Frontiers in sports and active living

    2022  Volume 4, Page(s) 835659

    Abstract: The pole vault is a highly technical event where the athletes must successfully convert horizontal velocity during the run-up to vertical velocity at take-off. The aim of this study was to compare the kinematics of men's and women's world-class pole ... ...

    Abstract The pole vault is a highly technical event where the athletes must successfully convert horizontal velocity during the run-up to vertical velocity at take-off. The aim of this study was to compare the kinematics of men's and women's world-class pole vaulting. Video data were collected of the best clearances by 14 men and 11 women at the 2018 IAAF World Indoor Championships using three high-speed cameras (200 Hz). Running velocity, step lengths, step times, and pole angles were measured during the run-up; during take-off, distance from the plant box, angle and velocity of take-off, and relative positions of the foot and hands were measured. Men achieved greater clearance heights with faster run-ups, faster take-off velocities and higher hand grip positions (all
    Language English
    Publishing date 2022-04-06
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2022.835659
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Kinematic and Temporal Differences Between World-Class Men's and Women's Hurdling Techniques.

    Bissas, Athanassios / Paradisis, Giorgos P / Hanley, Brian / Merlino, Stéphane / Walker, Josh

    Frontiers in sports and active living

    2022  Volume 4, Page(s) 873547

    Abstract: This study aimed to compare joint kinematics and center of mass parameters throughout hurdle clearance between world-class men and women sprint hurdlers, who were competing in a World Championships final. This was the first study to present time-series ... ...

    Abstract This study aimed to compare joint kinematics and center of mass parameters throughout hurdle clearance between world-class men and women sprint hurdlers, who were competing in a World Championships final. This was the first study to present time-series kinematic data around hurdle clearance, and given the technical ability of the athletes analyzed, it can be used as a template when analyzing the technique of other athletes in similar competitions and training. Video data were collected of the 16 finalists at the 2017 IAAF World Championships using four high-speed cameras (150 Hz). Video files were continuously digitized manually from touchdown before hurdle clearance to toe-off after landing around the sixth hurdle for men and the fifth hurdle for women, and sex-based comparisons were made at key discrete time points using independent
    Language English
    Publishing date 2022-04-29
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2022.873547
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Estimates of economic and environmental damages from tipping points cannot be reconciled with the scientific literature.

    Keen, Steve / Lenton, Timothy M / Garrett, Timothy J / Rae, James W B / Hanley, Brian P / Grasselli, Matheus

    Proceedings of the National Academy of Sciences of the United States of America

    2022  Volume 119, Issue 21, Page(s) e2117308119

    Language English
    Publishing date 2022-05-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2117308119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Call for a Three-Tiered Pandemic Public Health Strategy in Context of SARS-CoV-2

    Hanley, Brian P. / Keen, Steve / Church, George

    Rejuvenation Research

    2020  Volume 23, Issue 4, Page(s) 281–283

    Keywords Ageing ; Geriatrics and Gerontology ; covid19
    Language English
    Publisher Mary Ann Liebert Inc
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2150779-X
    ISSN 1557-8577 ; 1549-1684
    ISSN (online) 1557-8577
    ISSN 1549-1684
    DOI 10.1089/rej.2020.2363
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Biomechanics of World-Class Men and Women Hurdlers.

    Hanley, Brian / Walker, Josh / Paradisis, Giorgos P / Merlino, Stéphane / Bissas, Athanassios

    Frontiers in sports and active living

    2021  Volume 3, Page(s) 704308

    Abstract: The sprint hurdle events require athletes to cross ten hurdles between the start and finish line. The height of the hurdles, and the distances between them, differ for men and women, possibly resulting in technical differences. The aim of this study was ... ...

    Abstract The sprint hurdle events require athletes to cross ten hurdles between the start and finish line. The height of the hurdles, and the distances between them, differ for men and women, possibly resulting in technical differences. The aim of this study was to provide a kinematic comparison of in-competition hurdle technique for world-class men and women hurdlers. Video data were collected for the 16 finalists in the 100 m and 110 m hurdles events at the 2017 IAAF World Championships using four high-speed cameras (150 Hz), focusing on the sixth hurdle for the men and fifth for the women. Center of mass (CM) position, joint angles, step lengths and clearance times were compared between sexes at key events before, during and after hurdle clearance. The hurdle height was ~7% higher for men when calculated as a proportion of stature (
    Language English
    Publishing date 2021-07-08
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2624-9367
    ISSN (online) 2624-9367
    DOI 10.3389/fspor.2021.704308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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