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Article: A case report of Mpox (Monkeypox) in male traveler.

AlBahrani, Salma / AlGarzai, Ruba / Aljunaid, Thamir O / Al-Tawfiq, Jaffar A

2023 Volume 53, Page(s) 101132

Language	English
Publishing date	2023-05-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2750179-6
ISSN	2052-2975
ISSN	2052-2975
DOI	10.1016/j.nmni.2023.101132
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Article ; Online: Dynamic Patterns and Predominance of Respiratory Pathogens Post-COVID-19: Insights from a Two-Year Analysis.

AlBahrani, Salma / AlZahrani, Samira Jamaan / Al-Maqati, Thekra N / Almehbash, Atheer / Alshammari, Anfal / Bujlai, Refan / Ba Taweel, Sarah / Almasabi, Fares / AlAmari, Abdullah / Al-Tawfiq, Jaffar A

Journal of epidemiology and global health

2024

Abstract: Introduction: Respiratory tract infections (RTIs) stand out as the most frequent causes leading to visits to the emergency department and hospitalizations. This study aims to assess the types and prevalence of respiratory infections across two years ... ...

Abstract	Introduction: Respiratory tract infections (RTIs) stand out as the most frequent causes leading to visits to the emergency department and hospitalizations. This study aims to assess the types and prevalence of respiratory infections across two years following the end of the COVID-19 pandemic. Methods: Patients presenting with an influenza-like illness (ILI) were tested using multiplex RT-PCR (QIAstat-Dx, Qiagen). The multiplexed RT- PCR test detects 21 respiratory viruses and bacteria. Results: During the study period, PCR test was done on a total of 1,790 samples were tested, and 712 (40%) were positive for a total of 796 pathogens. The mean age (± SD) of the participants was 20.1 ± 28.4 years in 2022 and 21.9 ± 27.6 years in 2023. Among the detected pathogens, the most prevalent were Rhinovirus/Enterovirus 222 (12.4%), followed by RSV A&B (103 cases, 5.7%), and H1N1 Influenza (77 cases, 4.3%). Additionally, Influenza A/B constituted 172 (9.6%) while parainfluenza constituted (58, 3.2%). SARS-CoV-2 was identified in 3.97% of the samples. Over the two-year period, the monthly pattern of the identified pathogens exhibited fluctuations in the prevalence. Furthermore, variations were observed in the detected pathogens across different age groups. Conclusion: In addition to adding significant knowledge to the field of respiratory viral infections, this study emphasizes the necessity of ongoing research and surveillance for the detection and characterization of respiratory viruses, particularly those with the potential for emergence. Such studies would also require setting up a strategy for genotyping and/or sequencing of viruses.
Language	English
Publishing date	2024-04-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2645324-1
ISSN	2210-6014 ; 2210-6014
ISSN (online)	2210-6014
ISSN	2210-6014
DOI	10.1007/s44197-024-00213-9
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Article: The Association of Body Mass Index with COVID-19 Complications and Survival Rate at a Tertiary Hospital.

AlBahrani, Salma / Al-Maqati, Thekra N / Al Naam, Yaser A / Alqahtani, Jaber S / Alqahtani, Abdullah S / AlRabeeah, Saad / Aldhahir, Abdulelah M / Alkhalaf, Faisal / Alzuraiq, Hind R / Alenezi, Maryam Hamad / Alzahrani, Amal / Bakkar, Mohanad / Albahrani, Zainab / Maawadh, Rawan M

Life (Basel, Switzerland)

2023 Volume 13, Issue 7

Abstract: A high body mass index (BMI) is a known risk factor for coronavirus infection in hospitalized patients. Our study examined the association between BMI and complications and the survival rate among COVID-19 patients. This retrospective analysis used data ... ...

Abstract	A high body mass index (BMI) is a known risk factor for coronavirus infection in hospitalized patients. Our study examined the association between BMI and complications and the survival rate among COVID-19 patients. This retrospective analysis used data from a tertiary hospital in the Eastern Region of Saudi Arabia during two waves of the COVID-19 pandemic. The study included 600 participants, with the majority being between 41 and 60 years old (41.3%) and men comprising 63.5% of the sample. Approximately 42.5% of patients were obese, and 31.3% were overweight. The results showed that BMI was significantly linked to respiratory diseases (
Language	English
Publishing date	2023-07-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life13071572
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Article: Outcome of early short-course corticosteroids in hospitalized patients with coronavirus disease-2019 (COVID-19): A report from a Saudi Arabian hospital.

Al-Bahrani, Salma Y / Al-Shammari, Amal S / Al-Otaibi, Maha J / Ahmed, Zubair R

Journal of family & community medicine

2021 Volume 28, Issue 2, Page(s) 125–128

Abstract: Background: The efficacy of corticosteroid use in patients with acute respiratory illness due to coronavirus disease-2019 (COVID-19) is unclear. In this study, we describe the clinical course of COVID-19 patients who received early course of ... ...

Abstract	Background: The efficacy of corticosteroid use in patients with acute respiratory illness due to coronavirus disease-2019 (COVID-19) is unclear. In this study, we describe the clinical course of COVID-19 patients who received early course of corticosteroid treatment in patients with severe respiratory distress secondary to COVID-19. Materials and methods: The clinical course of 30 COVID-19 patients admitted to King Fahad Military Medical Complex in Dhahran from the period of late March 2020 till June 2020 was assessed and described. All the 30 patients received steroids. Data on demographics, medical history, laboratory findings, chest radiology, medication use, and clinical outcomes were extracted from patients' records. Data was entered and analyzed with SPSS software. Results: A total of 30 patients admitted with COVID-19 were included. The mean age 52.53 years (SD=16.31) with a range from 22-98 years; 73.3% were males. About two-thirds of the patients at least had comorbidities; most common were diabetes (46.7%) and hypertension (46.7%), and chronic heart disease (16.7%). About 57% patients had fever, cough, and shortness of breath. The median C-reactive protein (CRP) level was 87.5 mg/dL (IQR 45.0 - 165.65); 46.7% had CRP levels >120 mg/dL. The median white blood cell, lymphocytes, and platelet counts were 4.39, 1.05, and 212 K/μL, respectively. All the patients received corticosteroids; 17 (56.7%) patients were given IV methylprednisolone and 13 (43.3%) received dexamethasone tablets. Of the total patients, 13 (43.3%) patients developed acute respiratory distress syndrome (ARDS); 17 (56.7%) required oxygen, 10 (33.3%) were admitted to Intensive Care Unit (ICU), and 7 (23.3%) required mechanical ventilation. All the patients improved and were discharged home well. Conclusion: Early use of oral corticosteroids in patients with higher CRP levels may lead to better outcomes and may lower risk of transfer to ICU and use of mechanical ventilation.
Language	English
Publishing date	2021-05-08
Publishing country	India
Document type	Case Reports
ZDB-ID	2580509-5
ISSN	2229-340X ; 1319-1683
ISSN (online)	2229-340X
ISSN	1319-1683
DOI	10.4103/jfcm.jfcm_69_21
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Article ; Online: Pattern of cephalosporin and carbapenem-resistant

AlBahrani, Salma / Alqazih, Thikrayat Qazih / Aseeri, Ali Ahmad / Al Argan, Reem / Alkhafaji, Dania / Alrqyai, Nora Abdullah / Alanazi, Sami Mohamed / Aldakheel, Dima Saleh / Ghazwani, Qassim Hassan / Jalalah, Salah Saeed / Alshuaibi, Anwar Khalid / Hazzazi, Hanadi Ali / Al-Tawfiq, Jaffar A

IJID regions

2023 Volume 10, Page(s) 31–34

Abstract: Objectives: Despite its financial cost on the world's health care system, : Methods: This retrospective analysis covered the period from January 2019 to December 2022 and included cephalosporin- and carbapenem-resistant : Results: During the time ... ...

Abstract	Objectives: Despite its financial cost on the world's health care system, Methods: This retrospective analysis covered the period from January 2019 to December 2022 and included cephalosporin- and carbapenem-resistant Results: During the time of the study, 1815 clinical isolates of Conclusion: This study emphasizes the alarming patterns of carbapenem and cephalosporin resistance among
Language	English
Publishing date	2023-11-19
Publishing country	England
Document type	Journal Article
ISSN	2772-7076
ISSN (online)	2772-7076
DOI	10.1016/j.ijregi.2023.11.012
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Article: Bilateral adrenal hemorrhage in antiphospholipid syndrome. Anticoagulation for the treatment of hemorrhage.

Aldaajani, Hana / Albahrani, Salma / Saleh, Khalid / Alghanim, Khawla

Saudi medical journal

2018 Volume 39, Issue 8, Page(s) 829–833

Abstract: A 43-year-old man with Hashimoto's thyroiditis and previous thromboembolic events treated with warfarin for 6 months, presented with right flank pain accompanied with vomiting, dizziness, and altered mental status 2 weeks after discontinuation of ... ...

Abstract	A 43-year-old man with Hashimoto's thyroiditis and previous thromboembolic events treated with warfarin for 6 months, presented with right flank pain accompanied with vomiting, dizziness, and altered mental status 2 weeks after discontinuation of warfarin. His clinical examination findings were unremarkable. Routine blood work showed lymphopenia, thrombocytopenia, and hypoosmolar hyponatremia. Random serum cortisol level was low (14 nmol/L). Computed tomography scan of the abdomen revealed bilateral bulky heterogeneous suprarenal gland surrounded by fat stranding representing adrenal hemorrhage. He was treated for acute adrenal crisis and subsequently started on hydrocortisone and fludrocortisone, with significant clinical improvement. His diagnosis was secondary antiphospholipid syndrome (APS) to systemic lupus erythematosus (SLE). Bilateral adrenal thrombosis lead to hemorrhage in the adrenals as a paradoxical effect after warfarin cessation and primarily caused by APS. Bilateral adrenal bleeding should lead to the suspicion of thrombophilic disorders, such as APS, with cautious anticoagulation as the treatment of choice.
MeSH term(s)	Adrenal Gland Diseases/diagnostic imaging ; Adrenal Gland Diseases/drug therapy ; Adrenal Gland Diseases/etiology ; Adult ; Anticoagulants/therapeutic use ; Antiphospholipid Syndrome/complications ; Hashimoto Disease/complications ; Hemorrhage/diagnostic imaging ; Hemorrhage/drug therapy ; Hemorrhage/etiology ; Humans ; Lupus Erythematosus, Systemic/complications ; Male ; Tomography, X-Ray Computed
Chemical Substances	Anticoagulants
Language	English
Publishing date	2018-09-23
Publishing country	Saudi Arabia
Document type	Case Reports ; Journal Article
ZDB-ID	392302-2
ISSN	1658-3175 ; 0379-5284
ISSN (online)	1658-3175
ISSN	0379-5284
DOI	10.15537/smj.2018.8.22437
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Article ; Online: Clinical Features and Outcome of Low and High Corticosteroids in Admitted COVID-19 Patients.

AlBahrani, Salma / Al-Tawfiq, Jaffar A / Jebakumar, Arulanantham Zachariah / Alghamdi, Mohammed / Zakary, Nawaf / Seria, Mariam / Alrowis, Abdulrahman

Journal of epidemiology and global health

2021 Volume 11, Issue 3, Page(s) 316–319

Abstract: Introduction: There is no specific anti-viral therapies for 2019 Coronavirus Diseases (COVID-19) infection. Here, we compared patients receiving steroids at different dosages versus no steroids in severe and critical COVID-19 patients.: Methods: We ... ...

Abstract	Introduction: There is no specific anti-viral therapies for 2019 Coronavirus Diseases (COVID-19) infection. Here, we compared patients receiving steroids at different dosages versus no steroids in severe and critical COVID-19 patients. Methods: We retrospectively studied COVID-19 patients who received low-dose or high-dose corticosteroid therapy compared to no steroid. Results: The study period, June-August 2020, included 169 patients with COVID-19 were included and there were 39.1% female and 60.9% male with an average age of 53.1 years. The distribution of cases was as follows: high-dose 39 (23.1%), low-dose 54 (32.0%), and no steroid 76 (45.5%). Of all the patients, Intensive Care Unit (ICU) admission was for 31 (18.3%), nine (5.3%) required intubation, and 52 (30.8%) had no comorbidities. There is no difference in the mean age between the different groups. However, those being treated with steroid were more likely to have a high sequential organ failure assessment (SOFA) score (0.37 ± 0.68, 0.36 ± 0.67 and 0.04 ± 0.34, for low-dose, high-dose steroid and no steroid groups, respectively ( Conclusion: Cox regression was not possible as the mortality rate was very low (1.78%) and none of the multivariate methods would be possible as the model will not converge. However, in
MeSH term(s)	Adrenal Cortex Hormones ; COVID-19 ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2
Chemical Substances	Adrenal Cortex Hormones
Language	English
Publishing date	2021-06-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2645324-1
ISSN	2210-6014 ; 2210-6014
ISSN (online)	2210-6014
ISSN	2210-6014
DOI	10.2991/jegh.k.210521.001
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Article: Perinatal sacroiliitis diagnostic challenges.

Kheder, Emam M / Sharahili, Hussain H / Albahrani, Salma Y / Alfarhan, Abdullah M / Alquraynis, Abdulrahman M / Maitigue, Mahmoud B / Al Wehaibi, Ahmed M

SAGE open medical case reports

2021 Volume 9, Page(s) 2050313X211052442

Abstract: Lumbo-pelvic pain is a common and non-specific problem during pregnancy and postpartum. Although perinatal pyogenic sacroiliitis is uncommon during this time, it might be difficult to distinguish from reactive sacroiliitis in women who are experiencing ... ...

Abstract	Lumbo-pelvic pain is a common and non-specific problem during pregnancy and postpartum. Although perinatal pyogenic sacroiliitis is uncommon during this time, it might be difficult to distinguish from reactive sacroiliitis in women who are experiencing significant lower back and pelvic girdle pain, as the symptoms and signs are not clear and the tests are not definitive. A 34-year-old primigravida went to the emergency department with severe lower back pain radiating to the right gluteal region and down to the back of the right thigh. This pain began 12 days prior to her presentation and eventually worsened to the point that she could not stand or walk. Her vital signs were within normal ranges, and she was experiencing a fever. Apart from a slight widening of the symphysis pubis, her pelvic and lumbo-sacral pain X-rays revealed no important findings. With the clinical impression of right lumbo-pelvic pain, the patient was admitted for pain management and further inquiries. Despite the fact that the antibiotherapy was prescribed to treat a urinary tract infection, the significant recovery of the patient's symptoms, even in the absence of a definitive culture of aspirate from the right sacroiliac joint, supported the diagnosis of pyogenic sacroiliitis.
Language	English
Publishing date	2021-10-12
Publishing country	England
Document type	Case Reports
ZDB-ID	2736953-5
ISSN	2050-313X
ISSN	2050-313X
DOI	10.1177/2050313X211052442
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Article ; Online: A Case Series of Severe Hospitalized COVID-19 Patients Treated with Tocilizumab and Glucocorticoids: A Report from Saudi Arabian Hospital.

AlBahrani, Salma / Al-Tawfiq, Jaffar A / Alshaer, Abdulaziz R / Shilash, Amal / Alswefy, Khalid / Al-Zayer, Razan Salamah / Abouelela, Amr Mohamed

Journal of epidemiology and global health

2021 Volume 11, Issue 2, Page(s) 233–237

Abstract: Background: The clinical spectrum of COVID-19 is variable and ranges from asymptomatic, mildly symptomatic, moderately severe and severe disease. A small proportion might develop severe disease and may have cytokine storm. One of the therapeutic options ...

Abstract	Background: The clinical spectrum of COVID-19 is variable and ranges from asymptomatic, mildly symptomatic, moderately severe and severe disease. A small proportion might develop severe disease and may have cytokine storm. One of the therapeutic options to treat such cases is Tocilizumab (TCZ). In this study, we present cases of severe COVID-19 treated with TCZ and glucocorticoids and discuss the treatment responses. Methods: This is a retrospective observational study of severe COVID-19 cases treated with TCZ and glucocorticoids. The case series examined the characteristics and outcome of those patients. Results: This study included 40 Severe Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) confirmed patients who received TCZ and glucocorticoids. The mean age of the included patients was 57.55 (±Standard deviation 12.86) years. There were 34 (85%) males, 19 (47.5%) were obese (BMI >30), 13 (32.5%) over weight, and five (12.5%) normal weight. The mean days from positive SARS-CoV-2 polymerase chain reaction (PCR) test to admission was 1.641 (±3.2) days. Of the patients, 18 (45%) had diabetes mellitus, 14 (35%) had hypertension. The mean days from hospital admission to ICU was 1.8 (±2.6), 20 (50%) required mechanical ventilation, 39 (97.5%) had received prone position, seven (17.5%) had renal replacement therapy, 13 (32.5%) required inotropes, four (10%) had plasmapheresis, one (2.5%) had intravenous immunoglobulin, all patients received steroid therapy, and the majority 31 (77.5%) did not receive any anti-viral therapy. Of all the patients, six (15%) died, 28 (70%) were discharged and six (15%) were still in hospital. Conclusion: The overall mortality rate was lower than those cited in meta-analysis. As our understanding of the COVID-19 continues, the approach and therapeutics are also evolving.
MeSH term(s)	Antibodies, Monoclonal, Humanized/therapeutic use ; COVID-19/drug therapy ; COVID-19/mortality ; Female ; Glucocorticoids/therapeutic use ; Hospitals ; Humans ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2 ; Saudi Arabia/epidemiology ; Treatment Outcome
Chemical Substances	Antibodies, Monoclonal, Humanized ; Glucocorticoids ; tocilizumab (I031V2H011)
Language	English
Publishing date	2021-01-22
Publishing country	France
Document type	Journal Article ; Observational Study
ZDB-ID	2645324-1
ISSN	2210-6014 ; 2210-6014
ISSN (online)	2210-6014
ISSN	2210-6014
DOI	10.2991/jegh.k.210112.001
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Article ; Online: Clinical features and outcome of human Mpox (Monkeypox) in Saudi Arabia: An observational study of travel-related cases.

Assiri, Abdullah M / Al-Tawfiq, Jaffar A / Jokhdar, Hani A / Algwizani, Abdullah R / Albarraq, Ahmed M / Alanazi, Khalid H / Alamri, Ahlam H / Almohammadi, Emad L / Abuhasan, Musallam Y / Alserehi, Haleema A / Rebh, Fatimah Z / Alrossais, Amirah / Alawad, Eman / AlBahrani, Salma

Journal of infection and public health

2023 Volume 16, Issue 3, Page(s) 341–345

Abstract: Background: The 2022 Monkeypox virus (Mpox) outbreak had involved multiple countries around the globe. Here, we report clinical features and outcome of human Mpox of the first cases in Saudi Arabia.: Methods: We obtained records of confirmed Mpox ... ...

Abstract	Background: The 2022 Monkeypox virus (Mpox) outbreak had involved multiple countries around the globe. Here, we report clinical features and outcome of human Mpox of the first cases in Saudi Arabia. Methods: We obtained records of confirmed Mpox cases in Saudi Arabia from the public electronic health information system, Health Electronic Surveillance Network (HESN) and the healthcare providers completed a de-identified structured clinical data collection form. Results: The reported seven cases were travel-related and all were males between 24 and 41 years of age (mean age + SD) was 30.14 (+ 6.69) years. Of the cases, three (43 %) had heterosexual contact and the others had other intimate encounters while traveling abroad. They presented with skin lesions (100 %), fever (86 %), and lymphadenopathy (71 %). The illness was mild to moderate, did not require antiviral medications, and lasted 7-15 days. The mean duration of skin rash (+ SD) was 10 (+ 2.68) days. Routine laboratory tests (CBC, BUN, serum electrolytes, and liver enzymes) were within normal limits, and initial screening for HIV was negative. Expanded contact tracing did not reveal secondary cases of Mpox in the community or the healthcare setting. Conclusion: The current study showed heterosexual transmission of Mpox and the clinical course was mild and non-complicated. Therefore, clinicians and public health professionals should consider Mpox among individuals presenting with skin rash especially in the context of the investigation of HIV and other sexually transmitted diseases.
MeSH term(s)	Male ; Humans ; Young Adult ; Adult ; Female ; Mpox (monkeypox)/epidemiology ; Saudi Arabia/epidemiology ; Travel ; Travel-Related Illness ; Exanthema ; HIV Infections
Language	English
Publishing date	2023-01-13
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	2467587-8
ISSN	1876-035X ; 1876-0341
ISSN (online)	1876-035X
ISSN	1876-0341
DOI	10.1016/j.jiph.2023.01.006
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