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  1. Article ; Online: A Case of Acute Retinal Necrosis Associated with Reactivation of Varicella Zoster Virus after COVID-19 Vaccination.

    Iwai, Seima / Takayama, Kei / Sora, Daisuke / Takeuchi, Masaru

    Ocular immunology and inflammation

    2021  Volume 31, Issue 1, Page(s) 233–235

    Abstract: Purpose: To report a case of acute retinal necrosis (ARN) after receiving COVID-19 vaccination.: Methods: A case report.: Results: A 78-year-old man complained of blurred vision and floaters in the right eye 2 days after receiving BNT162b2 mRNA- ... ...

    Abstract Purpose: To report a case of acute retinal necrosis (ARN) after receiving COVID-19 vaccination.
    Methods: A case report.
    Results: A 78-year-old man complained of blurred vision and floaters in the right eye 2 days after receiving BNT162b2 mRNA-based COVID-19 vaccine and was referred to our hospital with worsening visual acuity after 7 days. He had no systemic symptoms and no history of systemic diseases. Ophthalmic examination revealed white-yellowish placoid lesions spreading to the entire circumference of the retina, and temporal and upper lesions extending to the posterior pole, although anterior inflammation and vitreous opacity were mild. Diagnostic and therapeutic vitrectomy was performed, and VZV-DNA was detected by comprehensive PCR using a vitreous fluid sample. The ocular inflammation subsided by systemic administration of antivirals and corticosteroids. However, total retinal detachment requiring repeat vitrectomy using silicone oil occurred after the second vaccination.
    Conclusion: ARN associated with VZV reactivation may develop after SARS-CoV-2 mRNA vaccination.
    MeSH term(s) Aged ; Humans ; Male ; BNT162 Vaccine ; COVID-19/diagnosis ; COVID-19/complications ; COVID-19 Vaccines/adverse effects ; Herpes Zoster Ophthalmicus/diagnosis ; Herpes Zoster Ophthalmicus/drug therapy ; Herpes Zoster Ophthalmicus/etiology ; Herpesvirus 3, Human/genetics ; Inflammation/complications ; Retinal Necrosis Syndrome, Acute/diagnosis ; Retinal Necrosis Syndrome, Acute/drug therapy ; Retinal Necrosis Syndrome, Acute/etiology ; SARS-CoV-2
    Chemical Substances BNT162 Vaccine ; COVID-19 Vaccines
    Language English
    Publishing date 2021-11-22
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2021.2001541
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4004: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Epidemiology and characteristics of common forms of anterior uveitis at initial presentation in a tertiary facility in Japan.

    Okazawa, Rina / Iwai, Seima / Nagura, Koichi / Sora, Daisuke / Sato, Tomohito / Takayama, Kei / Harimoto, Kozo / Kanda, Takayuki / Takeuchi, Masaru

    Japanese journal of ophthalmology

    2022  Volume 67, Issue 1, Page(s) 22–31

    Abstract: Purpose: To elucidate detailed epidemiological profile of common types of anterior uveitis (AU) in real-world clinical setting of a tertiary facility in Japan, and to evaluate the characteristic clinical findings at initial presentation.: Study design! ...

    Abstract Purpose: To elucidate detailed epidemiological profile of common types of anterior uveitis (AU) in real-world clinical setting of a tertiary facility in Japan, and to evaluate the characteristic clinical findings at initial presentation.
    Study design: Retrospective cohort study.
    Methods: Clinical charts of 275 patients (335 eyes) aged 52.5 ± 19.1 years were reviewed retrospectively. Herpetic AU was diagnosed by multiplex polymerase chain reaction tests using aqueous humor. Time of uveitis onset, gender, laterality, disease course since the initial onset of AU, visual acuity (VA) and intraocular pressure (IOP) at first visit, and definitive diagnosis were collected from clinical charts.
    Results: Acute AU (AAU) was the most common (21.8%) form of AU; followed by herpetic AU (20.7%) comprising Herpes Simplex Virus (HSV) (8.0%), Varicella Zoster Virus (VZV) (9.1%) and cytomegalo virus (CMV) (3.6%); scleritis (13.5%); diabetic iritis (7.6%), and Posner-Schlossman syndrome (5.5%). Unilateral AU constituted 78.2%, and VA less than 20/30 accounted for 31.2%. Of all the eyes, 16.1% had an IOP higher than 20 mmHg, out of which 37.0% had herpetic AU, followed by scleritis in 25.9%, and Posner-Schlossman syndrome (PSS) in 11.1%. AU patients over 60 years of age were 40.4%, in which 34.2% had herpetic AU, followed by scleritis in 14.4% and AAU in 13.5%. Herpetic AU patients were significantly older and had higher IOP compared with AAU patients.
    Conclusion: The most frequent AU was AAU, followed by herpetic AU. Herpetic AU patients were older and had higher intraocular pressure than AAU patients, although VA was equally impaired in both groups.
    MeSH term(s) Humans ; Middle Aged ; Aged ; Herpes Zoster Ophthalmicus/diagnosis ; Retrospective Studies ; Eye Infections, Viral/diagnosis ; Eye Infections, Viral/epidemiology ; Japan/epidemiology ; Scleritis ; Herpesvirus 3, Human/genetics ; Uveitis, Anterior/diagnosis ; Uveitis, Anterior/epidemiology ; Glaucoma ; Acute Disease ; Glaucoma, Open-Angle ; Aqueous Humor ; DNA, Viral/analysis
    Chemical Substances DNA, Viral
    Language English
    Publishing date 2022-11-08
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 82032-5
    ISSN 1613-2246 ; 0021-5155
    ISSN (online) 1613-2246
    ISSN 0021-5155
    DOI 10.1007/s10384-022-00961-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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