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  1. Article ; Online: Anti-Photoaging Effects of Upcycled

    Ko, Hyun-Ju / Sim, Su-An / Park, Mi-Hee / Ryu, Hwa-Sun / Choi, Won-Yeong / Park, Sung-Min / Lee, Jung-No / Hyun, Chang-Gu

    International journal of molecular sciences

    2024  Volume 25, Issue 3

    Abstract: Side streams and byproducts of food are established sources of natural ingredients in cosmetics. In the present study, we obtained upcycled low-molecular-weight anionic peptides (LMAPs) using byproducts of the post-yuzu-juicing process by employing an ... ...

    Abstract Side streams and byproducts of food are established sources of natural ingredients in cosmetics. In the present study, we obtained upcycled low-molecular-weight anionic peptides (LMAPs) using byproducts of the post-yuzu-juicing process by employing an enzyme derived from
    MeSH term(s) Skin Aging ; Citrus ; Skin/metabolism ; Cytokines/metabolism ; Skin Diseases/metabolism ; Ultraviolet Rays/adverse effects ; Fibroblasts/metabolism
    Chemical Substances Cytokines
    Language English
    Publishing date 2024-01-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25031711
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  2. Article ; Online: Sewage sludge steam gasification over bimetallic mesoporous Al-MCM48 catalysts for efficient hydrogen generation.

    Farooq, Abid / Ko, Chang Hyun / Park, Y-K

    Environmental research

    2023  Volume 224, Page(s) 115553

    Abstract: This study explored the potential of steam gasification of sewage sludge over different temperatures (non-catalytic) and bimetallic (Ni-Fe and Ni-Co) mesoporous Al-MCM48 (3-5% Al basis). The higher temperature (800 °C) resulted in higher gas yield (36.74  ...

    Abstract This study explored the potential of steam gasification of sewage sludge over different temperatures (non-catalytic) and bimetallic (Ni-Fe and Ni-Co) mesoporous Al-MCM48 (3-5% Al basis). The higher temperature (800 °C) resulted in higher gas yield (36.74 wt%) and syngas (H
    MeSH term(s) Steam ; Sewage ; Carbon Dioxide ; Alloys ; Hydrogen
    Chemical Substances Steam ; Sewage ; Carbon Dioxide (142M471B3J) ; Alloys ; Hydrogen (7YNJ3PO35Z)
    Language English
    Publishing date 2023-02-22
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.115553
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  3. Article: Characteristics of Early Pancreatic Cancer: Comparison between Stage 1A and Stage 1B Pancreatic Cancer in Multicenter Clinical Data Warehouse Study.

    Kim, Hyo Suk / Choi, Young Hoon / Lee, Jae Sin / Jo, Ik Hyun / Ko, Sung Woo / Paik, Kyu Hyun / Choi, Hyun Ho / Lee, Han Hee / Lim, Yeon Soo / Paik, Chang Nyol / Lee, In Seok / Chang, Jae Hyuck

    Cancers

    2024  Volume 16, Issue 5

    Abstract: Background: Little is known about the characteristics of early pancreatic cancer. We aimed to identify the characteristics, clues for early detection, and prognostic factors for early pancreatic cancer by analyzing a large number of patients with stage ... ...

    Abstract Background: Little is known about the characteristics of early pancreatic cancer. We aimed to identify the characteristics, clues for early detection, and prognostic factors for early pancreatic cancer by analyzing a large number of patients with stage 1 pancreatic cancer.
    Methods: A clinical data warehouse that includes databases of all the medical records of eight academic institutions was used to select and analyze patients with pancreatic cancer that had been diagnosed from January 2010 to May 2023.
    Results: In total, 257 stage 1 pancreatic cancer patients were included. There were 134 men (52%), and the average age was 67.2 ± 9.9 years. Compared to patients with stage 1B pancreatic cancer (2-4 cm), patients with stage 1A pancreatic cancer (≤2 cm) had more tumors in the body and tail than in the head (
    Conclusions: IPMN is closely associated with early pancreatic cancer and may provide an opportunity for early detection. The presence of perineural invasion was a crucial prognostic factor for both overall and disease-free survival in patients with stage 1 pancreatic cancer.
    Language English
    Publishing date 2024-02-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16050944
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  4. Article ; Online: Effect of dipeptidyl peptidase-4 inhibitor on the progression of coronary artery disease evaluated by computed tomography in patients receiving insulin therapy for type 2 diabetes mellitus.

    Choi, Young / Ko, Seung-Hyun / Chang, Kiyuk / Yoo, Ki Dong / Ihm, Sang-Hyun

    Journal of diabetes

    2023  Volume 15, Issue 11, Page(s) 944–954

    Abstract: ... rates, and changes in the coronary calcium score (CCS) were analyzed.: Results: A total of 623 ... group. The change in CCS per year did not differ significantly between the two groups (9.1 [0.1-56.8] vs ...

    Abstract Background: We evaluated the effect of a dipeptidyl peptidase-4 inhibitor (DPP-4i) on the progression of obstructive coronary artery disease (OCAD) in patients with type 2 diabetes mellitus (T2DM) receiving insulin therapy.
    Methods: Using a multicenter clinical data warehouse, we analyzed the patients receiving insulin therapy for T2DM who underwent coronary computed tomography angiography (CCTA) for ≥2 times. The patients were divided into two groups according to the presence of DPP-4i prescription between the two CCTA examinations. The prevalence of OCAD (>50% stenosis on CCTA), new revascularization rates, and changes in the coronary calcium score (CCS) were analyzed.
    Results: A total of 623 patients were included, and a DPP-4i was prescribed to 380 (60.9%) patients. The median time difference between the two CCTAs was 39.0 (17.0-61.4) months. Newly developed OCAD at the follow-up CCTA was detected in 62 (16.3%) patients in the DPP-4i group and 76 (31.3%) patients in the no DPP-4i group (p < 0.001). The risk of new OCAD or new revascularization was lower in the DPP-4i group (19.7% vs. 38.7%; p < 0.001). After propensity score matching, the prevalence of new OCAD (15.9% vs. 29.5%; p = 0.001) and the composite rate of new OCAD or new revascularization (18.7% vs. 37.3%; p < 0.001) were lower in the DPP-4i group. The change in CCS per year did not differ significantly between the two groups (9.1 [0.1-56.8] vs. 13.5 [0.0-78.6]; p = 0.715).
    Conclusions: Add-on DPP-4i therapy would be beneficial in preventing coronary artery disease progression in patients with T2DM receiving insulin therapy.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/epidemiology ; Dipeptidyl-Peptidase IV Inhibitors/therapeutic use ; Insulin/therapeutic use ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/drug therapy ; Hypoglycemic Agents/therapeutic use ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/therapeutic use ; Tomography
    Chemical Substances Dipeptidyl-Peptidase IV Inhibitors ; Insulin ; Hypoglycemic Agents ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases (EC 3.4.14.-)
    Language English
    Publishing date 2023-08-01
    Publishing country Australia
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2503337-2
    ISSN 1753-0407 ; 1753-0393
    ISSN (online) 1753-0407
    ISSN 1753-0393
    DOI 10.1111/1753-0407.13449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Alternative position of cannulae in veno-venous extracorporeal membrane oxygenation for maintaining sufficient flow support.

    Ko, Ui Won / Choi, Chang Hyu / Park, Chul-Hyun / Lee, Seok In

    General thoracic and cardiovascular surgery

    2023  Volume 71, Issue 6, Page(s) 369–372

    Abstract: Blood flow disturbance of veno-venous extracorporeal membrane oxygenation (VV-ECMO) can be a risk factor of weaning failure. We report an alternative position of cannulae of VV-ECMO which can maintain blood flow. The recirculation rate could be ... ...

    Abstract Blood flow disturbance of veno-venous extracorporeal membrane oxygenation (VV-ECMO) can be a risk factor of weaning failure. We report an alternative position of cannulae of VV-ECMO which can maintain blood flow. The recirculation rate could be controlled by adjusting a position of return cannula using dilutional ultrasound monitoring.
    MeSH term(s) Humans ; Cannula ; Extracorporeal Membrane Oxygenation ; Hemodynamics
    Language English
    Publishing date 2023-03-10
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2376888-5
    ISSN 1863-6713 ; 1863-6705
    ISSN (online) 1863-6713
    ISSN 1863-6705
    DOI 10.1007/s11748-023-01924-9
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  6. Article ; Online: Enhancing microbial CO

    Su Kim, Hui / Lee, Sangmin / Moon, Myounghoon / Jong Jung, Hwi / Lee, Jiye / Chu, Young-Hwan / Rae Kim, Jung / Kim, Danbee / Woo Park, Gwon / Hyun Ko, Chang / Youn Lee, Soo

    ChemSusChem

    2024  , Page(s) e202301342

    Abstract: Microbial ... ...

    Abstract Microbial CO
    Language English
    Publishing date 2024-01-29
    Publishing country Germany
    Document type Journal Article
    ISSN 1864-564X
    ISSN (online) 1864-564X
    DOI 10.1002/cssc.202301342
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  7. Article ; Online: Comparative Study of Efficacy Between Cyclosporine and Alitretinoin in Patients With Chronic Hand Eczema.

    Jang, Jin Hyun / Joh, Hae Chang / Song, Chang Hwa / Kim, Ki Yeon / Jue, Mihn Sook / Ro, Young Suck / Ko, Joo Yeon

    Dermatitis : contact, atopic, occupational, drug

    2023  

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-10-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1089/derm.2023.0113
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  8. Article ; Online: Association between prurigo nodularis and behavioural patterns of attention-deficit/hyperactivity disorder in children with atopic dermatitis: A cross-sectional study.

    Kim, Youngbeom / Lee, Jungsoo / Shin, Kihyuk / Kim, Hoon-Soo / Kim, Byungsoo / Kim, Moon-Bum / Ko, Hyun-Chang

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2024  

    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.19967
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  9. Article ; Online: Predictive Factors of Recurrence after Endovascular Treatment of Unruptured Vertebrobasilar Fusiform Aneurysms.

    Kim, Jae Hyun / Ko, Young San / Kwon, Sae Min / Kim, Chang Hyun / Lee, Chang Young

    Clinical neuroradiology

    2022  Volume 33, Issue 1, Page(s) 73–86

    Abstract: ... diameter and length, preoperative modified Rankin Scale (mRS) score ≥ 2, sole stenting technique, and intra ...

    Abstract Purpose: This study aimed to investigate the predictive factors of recurrence after endovascular treatment (EVT) for unruptured vertebrobasilar fusiform aneurysms (VBFA).
    Methods: This single-center retrospective study evaluated 36 patients who underwent EVT of unruptured VBFA between 2008 and 2020. Variables influencing recurrence, such as size, type, thrombus, preoperative symptoms, and treatment methods, were analyzed. All patients were followed up using vessel imaging.
    Results: In total, 7 of 36 patients (19.4%) developed recurrence. The mean time from EVT to recurrence was 9.2 months (range 2-26.9 months). Maximum aneurysmal diameter on magnetic resonance imaging was decreased, increased, and remained unchanged in 1, 7, and 28 patients, respectively. Transitional type VBFA, brain compression symptoms, large aneurysmal diameter and length, preoperative modified Rankin Scale (mRS) score ≥ 2, sole stenting technique, and intra-aneurysmal thrombus significantly influenced the risk of recurrence. Post-EVT, 7 (19.4%) patients showed complete occlusion of the aneurysm on the immediate postoperative angiogram, and 22 (61.1%) patients showed complete occlusion on the 1‑year follow-up imaging. Good outcomes were observed in 32 patients (88.9%) at the last follow-up, with a mRS score of 0-1 after EVT.
    Conclusion: EVT achieves good outcomes in unruptured VBFA. Transitional type VBFA, brain compression symptoms, large aneurysmal diameter and length, preoperative mRS score ≥ 2, sole stenting technique, and intra-aneurysmal thrombus are risk factors for aneurysm recurrence after EVT.
    MeSH term(s) Humans ; Intracranial Aneurysm/diagnostic imaging ; Intracranial Aneurysm/surgery ; Treatment Outcome ; Retrospective Studies ; Embolization, Therapeutic/methods ; Magnetic Resonance Imaging
    Language English
    Publishing date 2022-06-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2234662-4
    ISSN 1869-1447 ; 0939-7116 ; 1869-1439
    ISSN (online) 1869-1447
    ISSN 0939-7116 ; 1869-1439
    DOI 10.1007/s00062-022-01184-9
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  10. Article: Does the Surgical Approach Matter in Treating Odontoid Fractures? A Comparison of Mechanical Complication Rates Between Anterior Versus Posterior Surgical Approaches: A Meta-Analysis and Systematic Review.

    Jo, Woong Rae / Lee, Chang-Young / Kwon, Sae Min / Kim, Chang-Hyun / Kwon, Min-Yong / Kim, Jae Hyun / Ko, Young San

    Korean journal of neurotrauma

    2023  Volume 19, Issue 4, Page(s) 409–421

    Abstract: Objective: Odontoid fractures are treated surgically through the anterior or posterior approach. Each surgical approach has its advantages and disadvantages, so the preferred approach remains debatable. There are few meta-analyses or systemic reviews on ...

    Abstract Objective: Odontoid fractures are treated surgically through the anterior or posterior approach. Each surgical approach has its advantages and disadvantages, so the preferred approach remains debatable. There are few meta-analyses or systemic reviews on the mechanical complications of surgical treatment for odontoid fractures. This meta-analysis aimed to compare the operation-related morbidity, including mechanical complications, and mortality of patients with odontoid fractures, treated via the anterior or posterior approach.
    Methods: A systematic search was performed on PubMed/Medline, Embase, and the Cochrane Library for the studies up to October 2023 on the complication rate of the surgical treatment of odontoid fractures, related to the surgical approach. The risk ratios (RR) with the 95% confidence intervals (CIs) were pooled to assess the mechanical complication rates, other complications, revision surgery, and mortality, depending on the surgical approach.
    Results: A total of 1,519 studies were retrieved using the search strategy, and 782 patients from 15 articles were included in this meta-analysis. Mechanical complications were significantly more frequent in the anterior surgical group with low heterogeneity. The incidences of fracture nonunion and revision surgery were also higher in the anterior surgery group. However, there was no significant difference in systemic complications and mortality rates between the two groups.
    Conclusion: The posterior approach was more advantageous than the anterior approach in terms of mechanical complications, fusion rates, and incidence of revision surgery. However, further studies, should be performed to strengthen these results.
    Language English
    Publishing date 2023-12-26
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 3028579-3
    ISSN 2288-2243 ; 2234-8999
    ISSN (online) 2288-2243
    ISSN 2234-8999
    DOI 10.13004/kjnt.2023.19.e64
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