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  1. Article: Rituximab Not Effective for Hearing Loss in Cogan's Syndrome.

    Bunker, Daniel R / Kerr, Leslie Dubin

    Case reports in rheumatology

    2016  Volume 2016, Page(s) 8352893

    Abstract: ... ...

    Abstract Importance
    Language English
    Publishing date 2016-10-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2666708-3
    ISSN 2090-6897 ; 2090-6889
    ISSN (online) 2090-6897
    ISSN 2090-6889
    DOI 10.1155/2016/8352893
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  2. Article: A Case of Leukocytoclastic Vasculitis Caused by Listeria monocytogenes Bacteremia.

    Bunker, Daniel R / Sullivan, Timothy

    Case reports in infectious diseases

    2016  Volume 2016, Page(s) 1093453

    Abstract: Importance. Infections can cause leukocytoclastic vasculitis. Observations. We report the case of a patient with a left ventricular assist device who presented with acute kidney injury and biopsy proven leukocytoclastic vasculitis. Blood cultures grew ... ...

    Abstract Importance. Infections can cause leukocytoclastic vasculitis. Observations. We report the case of a patient with a left ventricular assist device who presented with acute kidney injury and biopsy proven leukocytoclastic vasculitis. Blood cultures grew Listeria monocytogenes. The patient's rash improved with treatment of the underlying Listeria infection. Conclusion. Clinicians should be aware that there are a number of broad categories of disease associated with the histologic finding of vasculitis, including infection. It is important to keep in mind the risk factors of a particular patient when formulating a differential diagnosis. This is the first reported case of Listeria bacteremia causing leukocytoclastic vasculitis.
    Language English
    Publishing date 2016-05-29
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2627642-2
    ISSN 2090-6633 ; 2090-6625
    ISSN (online) 2090-6633
    ISSN 2090-6625
    DOI 10.1155/2016/1093453
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  3. Article: Polycystic Ovary Syndrome Phenotype D Versus Functional Hypothalamic Amenorrhea With Polycystic Ovarian Morphology: A Retrospective Study About a Frequent Differential Diagnosis.

    Beitl, Klara / Dewailly, Didier / Seemann, Rudolf / Hager, Marlene / Bünker, Jakob / Mayrhofer, Daniel / Holzer, Iris / Ott, Johannes

    Frontiers in endocrinology

    2022  Volume 13, Page(s) 904706

    Abstract: The two most frequent causes of secondary amenorrhea are polycystic ovary syndrome (PCOS) and functional hypothalamic amenorrhea (FHA). Despite several studies showing differences in hormonal profile between these groups, the differential diagnosis ... ...

    Abstract The two most frequent causes of secondary amenorrhea are polycystic ovary syndrome (PCOS) and functional hypothalamic amenorrhea (FHA). Despite several studies showing differences in hormonal profile between these groups, the differential diagnosis remains challenging, in particular between FHA women with polycystic ovarian morphology (FHA-PCOM) and PCOS patients without hyperandrogenism (phenotype D, PCOS-D). In a retrospective case-control study, 58 clearly defined patients with FHA-PCOM were compared to 58 PCOS-D patients, matched 1:1 for age and BMI. Significantly higher levels of LH, estradiol, testosterone, and a higher luteinizing hormone (LH): follicle stimulating hormone (FSH) ratio as well as lower sexual hormone binding globulin (SHBG) levels were found in PCOS-D patients (
    MeSH term(s) Amenorrhea/diagnosis ; Amenorrhea/etiology ; Case-Control Studies ; Diagnosis, Differential ; Estradiol ; Female ; Follicle Stimulating Hormone ; Humans ; Luteinizing Hormone ; Phenotype ; Polycystic Ovary Syndrome/complications ; Polycystic Ovary Syndrome/diagnosis ; Retrospective Studies ; Testosterone
    Chemical Substances Testosterone (3XMK78S47O) ; Estradiol (4TI98Z838E) ; Luteinizing Hormone (9002-67-9) ; Follicle Stimulating Hormone (9002-68-0)
    Language English
    Publishing date 2022-06-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2022.904706
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  4. Article ; Online: Ixekizumab-Induced Serum Sickness (Like Reaction): An Unusual Adverse Effect.

    Lindberg, Michael R / Todd, Sarah P / Bunker, Daniel R / DeKlotz, Cynthia M C

    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

    2019  Volume 27, Issue 8S, Page(s) S469–S470

    MeSH term(s) Antibodies, Monoclonal, Humanized/adverse effects ; Dermatologic Agents ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Psoriasis/chemically induced ; Psoriasis/diagnosis ; Psoriasis/drug therapy ; Serum Sickness/chemically induced ; Serum Sickness/diagnosis ; Treatment Outcome
    Chemical Substances Antibodies, Monoclonal, Humanized ; Dermatologic Agents ; ixekizumab (BTY153760O)
    Language English
    Publishing date 2019-12-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1283266-2
    ISSN 1536-7355 ; 1076-1608
    ISSN (online) 1536-7355
    ISSN 1076-1608
    DOI 10.1097/RHU.0000000000001222
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4815: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Seamless EMR data access: Integrated governance, digital health and the OMOP-CDM.

    Hallinan, Christine Mary / Ward, Roger / Hart, Graeme K / Sullivan, Clair / Pratt, Nicole / Ng, Ashley P / Capurro, Daniel / Van Der Vegt, Anton / Liaw, Siaw-Teng / Daly, Oliver / Luxan, Blanca Gallego / Bunker, David / Boyle, Douglas

    BMJ health & care informatics

    2024  Volume 31, Issue 1

    Abstract: ... ...

    Abstract Objectives
    MeSH term(s) Humans ; Digital Health ; Electronic Health Records ; Delivery of Health Care ; Databases, Factual ; Data Management
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2632-1009
    ISSN (online) 2632-1009
    DOI 10.1136/bmjhci-2023-100953
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  6. Article ; Online: Rituximab Not Effective for Hearing Loss in Cogan’s Syndrome

    Daniel R. Bunker / Leslie Dubin Kerr

    Case Reports in Rheumatology, Vol

    2016  Volume 2016

    Abstract: Importance. Rituximab was not effective in ameliorating the hearing loss in a patient with atypical Cogan’s syndrome. Observations. We report the case of a patient who developed acute bilateral uveitis and sensorineural hearing loss. A diagnosis of ... ...

    Abstract Importance. Rituximab was not effective in ameliorating the hearing loss in a patient with atypical Cogan’s syndrome. Observations. We report the case of a patient who developed acute bilateral uveitis and sensorineural hearing loss. A diagnosis of atypical Cogan’s syndrome was made. The patient’s hearing loss did not improve despite high dose steroids and azathioprine. Rituximab was administered given a recent report of its efficacy in a patient with refractory disease; however, our patient’s hearing loss did not improve. Conclusion. Hearing loss in Cogan’s syndrome is difficult to treat. Though rituximab was ineffective in our case, earlier administration in the disease course could be effective for future patients.
    Keywords Internal medicine ; RC31-1245 ; Diseases of the musculoskeletal system ; RC925-935
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: A snapshot of climate drivers and temporal variation of

    Fan, Xueyang / Ma, Rui / Yue, Changjuan / Liu, Jiabin / Yue, Bisong / Yang, Wanjing / Li, Yunli / Gu, Jiang / Ayala, James E / Bunker, Daniel E / Yan, Xia / Qi, Dunwu / Su, Xiaoyan / Li, Lin / Zhang, Dongsheng / Zhang, Hongwen / Yang, Zhisong / Hou, Rong / Liu, Songrui

    International journal for parasitology. Parasites and wildlife

    2023  Volume 20, Page(s) 162–169

    Abstract: Ticks and tick-borne diseases have negative impacts on the health of wild animals including endangered and vulnerable species. The giant panda ( ...

    Abstract Ticks and tick-borne diseases have negative impacts on the health of wild animals including endangered and vulnerable species. The giant panda (
    Language English
    Publishing date 2023-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2715239-X
    ISSN 2213-2244
    ISSN 2213-2244
    DOI 10.1016/j.ijppaw.2023.02.005
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  8. Article ; Online: A 26-year-old woman with respiratory decompensation in the immediate postpartum period at Mount Sinai Medical Center in New York City.

    Bunker, Daniel R / Meinhof, Klaus T / Hiensch, Robert J / Ghaw, Olivia / Becker, Christian D

    Thorax

    2015  Volume 70, Issue 11, Page(s) 1095–1097

    MeSH term(s) Adult ; Bronchoscopy ; Female ; Humans ; New York City ; Postpartum Period ; Radiography, Thoracic ; Respiratory Insufficiency/diagnosis
    Language English
    Publishing date 2015-11
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 204353-1
    ISSN 1468-3296 ; 0040-6376
    ISSN (online) 1468-3296
    ISSN 0040-6376
    DOI 10.1136/thoraxjnl-2015-207250
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    In stock of ZB MED Cologne/Königswinter

    Ui III Zs.83: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Feasibility, acceptability and validation of wearable devices for climate change and health research in the low-resource contexts of Burkina Faso and Kenya: Study protocol.

    Barteit, Sandra / Boudo, Valentin / Ouedraogo, Aristide / Zabré, Pascal / Ouremi, Lucienne / Sié, Ali / Munga, Stephen / Obor, David / Kwaro, Daniel / Huhn, Sophie / Bunker, Aditi / Sauerborn, Rainer / Gunga, Hanns-Christian / Maggioni, Martina A / Bärnighausen, Till

    PloS one

    2021  Volume 16, Issue 9, Page(s) e0257170

    Abstract: As the epidemiological transition progresses throughout sub-Saharan Africa, life lived with diseases is an increasingly important part of a population's burden of disease. The burden of disease of climate-sensitive health outcomes is projected to ... ...

    Abstract As the epidemiological transition progresses throughout sub-Saharan Africa, life lived with diseases is an increasingly important part of a population's burden of disease. The burden of disease of climate-sensitive health outcomes is projected to increase considerably within the next decades. Objectively measured, reliable population health data is still limited and is primarily based on perceived illness from recall. Technological advances like non-invasive, consumer-grade wearable devices may play a vital role in alleviating this data gap and in obtaining insights on the disease burden in vulnerable populations, such as heat stress on human cardiovascular response. The overall goal of this study is to investigate whether consumer-grade wearable devices are an acceptable, feasible and valid means to generate data on the individual level in low-resource contexts. Three hundred individuals are recruited from the two study locations in the Nouna health and demographic surveillance system (HDSS), Burkina Faso, and the Siaya HDSS, Kenya. Participants complete a structured questionnaire that comprises question items on acceptability and feasibility under the supervision of trained data collectors. Validity will be evaluated by comparing consumer-grade wearable devices to research-grade devices. Furthermore, we will collect demographic data as well as the data generated by wearable devices. This study will provide insights into the usage of consumer-grade wearable devices to measure individual vital signs in low-resource contexts, such as Burkina Faso and Kenya. Vital signs comprising activity (steps), sleep (duration, quality) and heart rate (hr) are important measures to gain insights on individual behavior and activity patterns in low-resource contexts. These vital signs may be associated with weather variables-as we gather them from weather stations that we have setup as part of this study to cover the whole Nouna and Siaya HDSSs-in order to explore changes in behavior and other variables, such as activity, sleep, hr, during extreme weather events like heat stress exposure. Furthermore, wearable data could be linked to health outcomes and weather events. As a result, consumer-grade wearables may serve as a supporting technology for generating reliable measurements in low-resource contexts and investigating key links between weather occurrences and health outcomes. Thus, wearable devices may provide insights to better inform mitigation and adaptation interventions in these low-resource settings that are direly faced by climate change-induced changes, such as extreme weather events.
    MeSH term(s) Adolescent ; Adult ; Burkina Faso ; Child ; Climate Change ; Feasibility Studies ; Female ; Health ; Health Resources ; Humans ; Kenya ; Male ; Middle Aged ; Research ; Surveys and Questionnaires ; Wearable Electronic Devices ; Young Adult
    Language English
    Publishing date 2021-09-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Validation Study
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0257170
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  10. Article ; Online: Long-term surveillance of SUDEP in drug-resistant epilepsy patients treated with VNS therapy.

    Ryvlin, Philippe / So, Elson L / Gordon, Charles M / Hesdorffer, Dale C / Sperling, Michael R / Devinsky, Orrin / Bunker, Mark T / Olin, Bryan / Friedman, Daniel

    Epilepsia

    2018  Volume 59, Issue 3, Page(s) 562–572

    Abstract: Objective: Limited data are available regarding the evolution over time of the rate of sudden unexpected death in epilepsy patients (SUDEP) in drug-resistant epilepsy. The objective is to analyze a database of 40 443 patients with epilepsy implanted ... ...

    Abstract Objective: Limited data are available regarding the evolution over time of the rate of sudden unexpected death in epilepsy patients (SUDEP) in drug-resistant epilepsy. The objective is to analyze a database of 40 443 patients with epilepsy implanted with vagus nerve stimulation (VNS) therapy in the United States (from 1988 to 2012) and assess whether SUDEP rates decrease during the postimplantation follow-up period.
    Methods: Patient vital status was ascertained using the Centers for Disease Control and Prevention's National Death Index (NDI). An expert panel adjudicated classification of cause of deaths as SUDEP based on NDI data and available narrative descriptions of deaths. We tested the hypothesis that SUDEP rates decrease with time using the Mann-Kendall nonparametric trend test and by comparing SUDEP rates of the first 2 years of follow-up (years 1-2) to longer follow-up (years 3-10).
    Results: Our cohort included 277 661 person-years of follow-up and 3689 deaths, including 632 SUDEP. Primary analysis demonstrated a significant decrease in age-adjusted SUDEP rate during follow-up (S = -27 P = .008), with rates of 2.47/1000 for years 1-2 and 1.68/1000 for years 3-10 (rate ratio 0.68; 95% confidence interval [CI] 0.53-0.87; P = .002). Sensitivity analyses confirm these findings.
    Significance: Our data suggest that SUDEP risk significantly decreases during long-term follow-up of patients with refractory epilepsy receiving VNS Therapy. This finding might reflect several factors, including the natural long-term dynamic of SUDEP rate, attrition, and the impact of VNS Therapy. The role of each of these factors cannot be confirmed due to the limitations of the study.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Death, Sudden/epidemiology ; Death, Sudden/prevention & control ; Drug Resistant Epilepsy/diagnosis ; Drug Resistant Epilepsy/mortality ; Drug Resistant Epilepsy/therapy ; Female ; Follow-Up Studies ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Population Surveillance ; Time Factors ; Treatment Outcome ; United States/epidemiology ; Vagus Nerve Stimulation/trends ; Young Adult
    Language English
    Publishing date 2018-01-16
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 216382-2
    ISSN 1528-1167 ; 0013-9580
    ISSN (online) 1528-1167
    ISSN 0013-9580
    DOI 10.1111/epi.14002
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 517: Show issues Location:
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    Zs.MO 475: Show issues

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