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  1. Article: Neuroma Treatment With the Acellular Nerve Allograft Reconstruction Technique.

    Bell, Jennifer A / Trotter, Collean / Gittings, Daniel / Schur, Mathew / Mohty, Kurt M / Lefebvre, Rachel / Stevanovic, Milan

    Cureus

    2023  Volume 15, Issue 5, Page(s) e39567

    Abstract: Treatment of a painful neuroma is a challenging problem for both the patient and the providers. Current surgical treatment options typically include excision of the neuroma and stump relation. However, with both treatment options, patients have high ... ...

    Abstract Treatment of a painful neuroma is a challenging problem for both the patient and the providers. Current surgical treatment options typically include excision of the neuroma and stump relation. However, with both treatment options, patients have high rates of persistent pain and rates of neuroma recurrence. We describe two patients with neuromas treated with our acellular nerve allograft reconstruction technique. This technique involves the excision of the neuroma and bridging the proximal nerve end to the surrounding tissue with an acellular nerve allograft. Both patients had immediate resolution of their neuropathic pain that was maintained at their final follow-up. Acellular nerve allograft reconstruction is a promising treatment option for the treatment of painful neuromas.
    Language English
    Publishing date 2023-05-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.39567
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Utilizing Google Trends to Track Online Interest in Elective Hand Surgery During the COVID-19 Pandemic.

    Mohty, Kurt M / Lashkari, Nassim / Gittings, Daniel J / Bell, Jennifer A / Stevanovic, Milan / Nicholson, Luke T

    Cureus

    2021  Volume 13, Issue 8, Page(s) e17313

    Abstract: Introduction Elective hand surgery encompasses a large volume of orthopaedic cases annually. Carpal tunnel syndrome, ganglion cysts, and trigger digits are some of the most common pathologies treated by hand surgeons. In the midst of the COVID-19 ... ...

    Abstract Introduction Elective hand surgery encompasses a large volume of orthopaedic cases annually. Carpal tunnel syndrome, ganglion cysts, and trigger digits are some of the most common pathologies treated by hand surgeons. In the midst of the COVID-19 pandemic, patient's interest in elective hand surgery for these conditions is uncertain. The objective of this study is to use Google Trends to track online interest in elective hand surgery in the United States during the COVID-19 pandemic. Methods Online search trends regarding elective orthopaedic hand surgery were obtained via Google Trends from November 2019 to November 2020. Three common hand pathologies in lay terms ("carpal tunnel," "'ganglion cyst' + 'wrist cyst,'" and "trigger finger") and three hand surgery-specific keywords ("hand surgery," "carpal tunnel surgery," and "trigger finger surgery") were used as search terms. The search volume index (SVI) graphs for the United States for both sets of search terms were then generated from the Google Trends data and compared to the seven-day average of new COVID-19 cases per day as reported by the CDC. A separate SVI graph was then created for the search term "coronavirus" and was compared against both sets of search terms as above. Results Search trends for all elective hand pathologies and surgery-specific keywords remained constant from November 2019 to the beginning of March 2020 and then decreased significantly within a one-month period following the peak in COVID-19 cases the week of March 15, 2020. Search trends for these keywords increased to baseline levels over the next few months. The search trend for "coronavirus" demonstrated a small search volume index peak of 13 during January 2020 followed by the maximum peak of 100 during the week of March 15, 2020, corresponding to the decrease in search trends of elective hand surgery at that time. Conclusions Online interest in elective hand surgery remained constant prior to the COVID-19 pandemic; however, there was a marked decrease in search trends of elective hand surgery with the rise in daily reported COVID-19 cases, suggesting that patient's interest in elective hand surgery decreased with the onset of the pandemic.
    Language English
    Publishing date 2021-08-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.17313
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Shoulder Surgery Google Search Trends during the COVID-19 Pandemic.

    Gittings, Daniel / Mohty, Kurt / Kelpin, John / Lashkari, Nassim / Stevanovic, Milan / Nicholson, Luke

    Journal of surgical orthopaedic advances

    2023  Volume 32, Issue 1, Page(s) 14–16

    Abstract: The Coronavirus disease 2019 (COVID-19) pandemic has strained many healthcare systems. Google Trends is a tool that provides information on online interest in selected keywords and topics over time. The purpose of this study is to describe the effect of ... ...

    Abstract The Coronavirus disease 2019 (COVID-19) pandemic has strained many healthcare systems. Google Trends is a tool that provides information on online interest in selected keywords and topics over time. The purpose of this study is to describe the effect of the COVID-19 pandemic on online interest in elective shoulder pathology. Online search pattern data were obtained via Google Trends from November 2019 to November 2020 using the search terms 'orthopedic surgery' and 'shoulder pathology' search terms. Relative search volume index (SVI) graphs were generated from this data and the 7-day average of new COVID-19 cases in the United States. Orthopaedic surgery and shoulder pathology search trends decreased during March 2020 with a sudden rise in the 7-day average of new COVID-19 cases. After March 2020, orthopaedic surgery and shoulder pathology search terms approached pre-COVID-19 pandemic values despite continued increases in the 7-day average of new COVID-19 cases. (Journal of Surgical Orthopaedic Advances 32(1):014-016, 2023).
    MeSH term(s) Humans ; United States/epidemiology ; COVID-19/epidemiology ; Pandemics ; Search Engine ; Shoulder ; Orthopedics
    Language English
    Publishing date 2023-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2189157-6
    ISSN 2158-3811 ; 1548-825X ; 1059-1052
    ISSN (online) 2158-3811
    ISSN 1548-825X ; 1059-1052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ultrasound Evaluation of Radial Nerve Palsy Associated with Humeral Shaft Fractures to Guide Operative Versus Non-Operative Treatment.

    Esparza, Melissa / Wild, Jason R / Minnock, Christopher / Mohty, Kurt M / Truchan, Lisa M / Taljanovic, Mihra S

    Acta medica academica

    2019  Volume 48, Issue 2, Page(s) 183–192

    Abstract: Objective: To determine the effectiveness of diagnostic ultrasound (US) at evaluating the condition of the radial nerve in the setting of humeral shaft fractures.: Materials and methods: An observational study was performed of 18 patients with radial ...

    Abstract Objective: To determine the effectiveness of diagnostic ultrasound (US) at evaluating the condition of the radial nerve in the setting of humeral shaft fractures.
    Materials and methods: An observational study was performed of 18 patients with radial nerve palsy associated with humeral shaft fractures who underwent US examination to assess the condition of the radial nerve.
    Results: Six patients with humeral shaft fractures treated nonoperatively in a functional brace had US findings consistent with contusion or stretch radial nerve injury. Twelve patients ultimately underwent surgery either because US showed an entrapped or lacerated radial nerve, or for other operative indications. There was a 92% concordance (11/12 patients) between US and intraoperative findings with regards to the condition and location of the radial nerve, with the remaining case being complicated by delayed surgical treatment secondary to patient factors.
    Conclusion: Our study demonstrates that US is an effective diagnostic tool in evaluating radial nerve injuries in the setting of humeral shaft fractures and can aid in clinical decision making by differentiating between patients with nerve laceration or entrapment who may benefit from surgery from those with neurapraxia managed nonoperatively.
    MeSH term(s) Accidental Falls ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Braces ; Clinical Decision-Making ; Female ; Humans ; Humeral Fractures/diagnostic imaging ; Humeral Fractures/etiology ; Humeral Fractures/surgery ; Lacerations/diagnostic imaging ; Lacerations/surgery ; Male ; Middle Aged ; Radial Nerve/diagnostic imaging ; Radial Nerve/injuries ; Radial Nerve/surgery ; Radial Neuropathy/diagnostic imaging ; Radial Neuropathy/surgery ; Treatment Outcome ; Ultrasonography ; Young Adult
    Language English
    Publishing date 2019-11-11
    Publishing country Bosnia and Herzegovina
    Document type Comparative Study ; Journal Article ; Observational Study
    ZDB-ID 2558604-X
    ISSN 1840-2879 ; 1840-1848
    ISSN (online) 1840-2879
    ISSN 1840-1848
    DOI 10.5644/ama2006-124.257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A Case of Persistent Low Back Pain in a Young Female Caused by a Trauma-Induced Schmorl's Node in the Lumbar Spine Five Vertebra.

    Mohty, Kurt M / Mandair, Divneet / Munroe, Brent / Baldemor, Deborah

    Cureus

    2017  Volume 9, Issue 7, Page(s) e1502

    Abstract: Physicians are often faced with managing difficult conditions such as chronic lower back pain. Intervertebral disk herniation typically occurs horizontally, leading to impingement of the spinal cord which can potentially cause radicular symptoms or other ...

    Abstract Physicians are often faced with managing difficult conditions such as chronic lower back pain. Intervertebral disk herniation typically occurs horizontally, leading to impingement of the spinal cord which can potentially cause radicular symptoms or other spinal cord pathologies; however, disk herniations can also occur vertically and extend through the endplate of an adjacent cranial or caudal vertebra: a phenomenon known as a Schmorl's node. Although Schmorl's nodes can be seen in many asymptomatic individuals, they can be a cause of degenerative disk disease and low back pain. An 18-year-old female with a history of trauma presented to urgent care with increasing lower back pain for the past six weeks. Four months prior, she was struck by a motor vehicle while riding her bicycle, and she had residual back pain since then. Plain radiography at the time of the accident showed no acute abnormalities. She had no other associated symptoms. On presentation, her vital signs were within normal limits, and her physical examination was largely unremarkable except for point tenderness along the lumbar (L4-L5) region of the spine. A complete blood count showed no leukocytosis and plain radiography of the lumbosacral spine showed a Schmorl's node in the inferior endplate of L5. The patient was diagnosed with a trauma-induced Schmorl's node and was treated with physical therapy, ice packs, and non-steroidal anti-inflammatory drugs. Her symptoms improved over the next several months. For patients with a history of axial load trauma and persistent back pain, clinicians should consider the possibility of a trauma-induced Schmorl's node. Plain radiography or magnetic resonance imaging can help with the diagnosis and guide further management.
    Language English
    Publishing date 2017-07-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.1502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cadaver-based Necrotizing Fasciitis Model for Medical Training.

    Mohty, Kurt M / Cravens, Matthew G / Adamas-Rappaport, William J / Amini-Shervin, Bahareh / Irving, Steven C / Stea, Nicholas / Adhikari, Srikar / Amini, Richard

    Cureus

    2017  Volume 9, Issue 4, Page(s) e1168

    Abstract: Necrotizing fasciitis is a devastating infectious disease process that is characterized by extensive soft tissue necrosis along deep fascial planes, systemic toxicity, and high mortality. Ultrasound imaging is a rapid and non-invasive tool that can be ... ...

    Abstract Necrotizing fasciitis is a devastating infectious disease process that is characterized by extensive soft tissue necrosis along deep fascial planes, systemic toxicity, and high mortality. Ultrasound imaging is a rapid and non-invasive tool that can be used to help make the diagnosis of necrotizing fasciitis by identifying several distinctive sonographic findings. The purpose of this study is to describe the construction of a realistic diagnostic training model for necrotizing fasciitis using fresh frozen cadavers and common, affordable materials. Presently, fresh non-embalmed cadavers have been used at medical institutions for various educational sessions including cadaver-based ultrasound training sessions. Details for the preparation and construction of a necrotizing fasciitis cadaver model are presented here. This paper shows that the images obtained from the cadaver model closely imitate the ultrasound appearance of fluid and gas seen in actual clinical cases of necrotizing fasciitis. Therefore, it can be concluded that this cadaver-based model produces high-quality sonographic images that simulate those found in true cases of necrotizing fasciitis and is ideal for demonstrating the sonographic findings of necrotizing fasciitis.
    Language English
    Publishing date 2017-04-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.1168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Standardizing Definitions of Hematopoietic Recovery, Graft Rejection, Graft Failure, Poor Graft Function, and Donor Chimerism in Allogeneic Hematopoietic Cell Transplantation: A Report on Behalf of the American Society for Transplantation and Cellular Therapy.

    Kharfan-Dabaja, Mohamed A / Kumar, Ambuj / Ayala, Ernesto / Aljurf, Mahmoud / Nishihori, Taiga / Marsh, Rebecca / Burroughs, Lauri M / Majhail, Navneet / Al-Homsi, A Samer / Al-Kadhimi, Zaid S / Bar, Merav / Bertaina, Alice / Boelens, Jaap J / Champlin, Richard / Chaudhury, Sonali / DeFilipp, Zachariah / Dholaria, Bhagirathbhai / El-Jawahri, Areej / Fanning, Suzanne /
    Fraint, Ellen / Gergis, Usama / Giralt, Sergio / Hamilton, Betty K / Hashmi, Shahrukh K / Horn, Biljana / Inamoto, Yoshihiro / Jacobsohn, David A / Jain, Tania / Johnston, Laura / Kanate, Abraham S / Kansagra, Ankit / Kassim, Adetola / Kean, Leslie S / Kitko, Carrie L / Knight-Perry, Jessica / Kurtzberg, Joanne / Liu, Hien / MacMillan, Margaret L / Mahmoudjafari, Zahra / Mielcarek, Marco / Mohty, Mohamad / Nagler, Arnon / Nemecek, Eneida / Olson, Timothy S / Oran, Betul / Perales, Miguel-Angel / Prockop, Susan E / Pulsipher, Michael A / Pusic, Iskra / Riches, Marcie L / Rodriguez, Cesar / Romee, Rizwan / Rondon, Gabriela / Saad, Ayman / Shah, Nina / Shaw, Peter J / Shenoy, Shalini / Sierra, Jorge / Talano, Julie / Verneris, Michael R / Veys, Paul / Wagner, John E / Savani, Bipin N / Hamadani, Mehdi / Carpenter, Paul A

    Transplantation and cellular therapy

    2021  Volume 27, Issue 8, Page(s) 642–649

    Abstract: Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for certain hematologic malignancies and nonmalignant diseases. The field of allo-HCT has witnessed significant advances, including broadening indications for ... ...

    Abstract Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for certain hematologic malignancies and nonmalignant diseases. The field of allo-HCT has witnessed significant advances, including broadening indications for transplantation, availability of alternative donor sources, less toxic preparative regimens, new cell manipulation techniques, and novel GVHD prevention methods, all of which have expanded the applicability of the procedure. These advances have led to clinical practice conundrums when applying traditional definitions of hematopoietic recovery, graft rejection, graft failure, poor graft function, and donor chimerism, because these may vary based on donor type, cell source, cell dose, primary disease, graft-versus-host disease (GVHD) prophylaxis, and conditioning intensity, among other variables. To address these contemporary challenges, we surveyed a panel of allo-HCT experts in an attempt to standardize these definitions. We analyzed survey responses from adult and pediatric transplantation physicians separately. Consensus was achieved for definitions of neutrophil and platelet recovery, graft rejection, graft failure, poor graft function, and donor chimerism, but not for delayed engraftment. Here we highlight the complexities associated with the management of mixed donor chimerism in malignant and nonmalignant hematologic diseases, which remains an area for future research. We recognize that there are multiple other specific, and at times complex, clinical scenarios for which clinical management must be individualized.
    MeSH term(s) Adult ; Child ; Chimerism ; Graft Rejection/prevention & control ; Hematopoietic Stem Cell Transplantation/adverse effects ; Humans ; Transplantation Conditioning ; Transplantation, Homologous ; United States
    Language English
    Publishing date 2021-07-19
    Publishing country United States
    Document type Practice Guideline ; Journal Article
    ZDB-ID 3062231-1
    ISSN 2666-6367
    ISSN (online) 2666-6367
    DOI 10.1016/j.jtct.2021.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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