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  1. Article: Navigating Early and Late Hematomas in Cochlear Implantation: A Tri-Case Analysis.

    Yazıcı, Zahide Mine / Gülüstan, Filiz / Koç, Recep Haydar / İnan, Burak Kaan / Aşaroğlu, Can Berk / Sayın, İbrahim

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2024  Volume 76, Issue 2, Page(s) 2141–2144

    Abstract: Cochlear implantation is a safe, popular procedure for severe hearing loss in both children and adults. Complications are categorized as major and minor, with hematomas and seromas being minor. This article discusses advanced diagnosis and treatment for ... ...

    Abstract Cochlear implantation is a safe, popular procedure for severe hearing loss in both children and adults. Complications are categorized as major and minor, with hematomas and seromas being minor. This article discusses advanced diagnosis and treatment for three patients with post-implantation hematomas (two early, one late).
    Language English
    Publishing date 2024-01-12
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-023-04471-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5300: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Screening for preclinical Alzheimer's disease: Deriving optimal policies using a partially observable Markov model.

    Önen Dumlu, Zehra / Sayın, Serpil / Gürvit, İbrahim Hakan

    Health care management science

    2022  Volume 26, Issue 1, Page(s) 1–20

    Abstract: Alzheimer's Disease (AD) is believed to be the most common type of dementia. Even though screening for AD has been discussed widely, there is no screening program implemented as part of a policy in any country. Current medical research motivates focusing ...

    Abstract Alzheimer's Disease (AD) is believed to be the most common type of dementia. Even though screening for AD has been discussed widely, there is no screening program implemented as part of a policy in any country. Current medical research motivates focusing on the preclinical stages of the disease in a modeling initiative. We develop a partially observable Markov decision process model to determine optimal screening programs. The model contains disease free and preclinical AD partially observable states and the screening decision is taken while an individual is in one of those states. An observable diagnosed preclinical AD state is integrated along with observable mild cognitive impairment, AD and death states. Transition probabilities among states are estimated using data from Knight Alzheimer's Disease Research Center (KADRC) and relevant literature. With an objective of maximizing expected total quality-adjusted life years (QALYs), the output of the model is an optimal screening program that specifies at what points in time an individual over 50 years of age with a given risk of AD will be directed to undergo screening. The screening test used to diagnose preclinical AD has a positive disutility, is imperfect and its sensitivity and specificity are estimated using the KADRC data set. We study the impact of a potential intervention with a parameterized effectiveness and disutility on model outcomes for three different risk profiles (low, medium and high). When intervention effectiveness and disutility are at their best, the optimal screening policy is to screen every year between ages 50 and 95, with an overall QALY gain of 0.94, 1.9 and 2.9 for low, medium and high risk profiles, respectively. As intervention effectiveness diminishes and/or its disutility increases, the optimal policy changes to sporadic screening and then to never screening. Under several scenarios, some screening within the time horizon is optimal from a QALY perspective. Moreover, an in-depth analysis of costs reveals that implementing these policies are either cost-saving or cost-effective.
    MeSH term(s) Humans ; Middle Aged ; Aged ; Aged, 80 and over ; Alzheimer Disease/diagnosis ; Sensitivity and Specificity ; Cost-Benefit Analysis ; Quality-Adjusted Life Years ; Markov Chains
    Language English
    Publishing date 2022-08-31
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1469148-6
    ISSN 1572-9389 ; 1386-9620
    ISSN (online) 1572-9389
    ISSN 1386-9620
    DOI 10.1007/s10729-022-09608-1
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    Zs.A 5158: Show issues Location:
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  3. Article: Association Between Plasma Asprosin Levels and Gestational Diabetes Mellitus.

    Boz, İbrahim Bekir / Aytürk Salt, Semra / Salt, Ömer / Sayın, Niyazi Cenk / Dibirdik, İlker

    Diabetes, metabolic syndrome and obesity : targets and therapy

    2023  Volume 16, Page(s) 2515–2521

    Abstract: Purpose: This study sought to investigate whether asprosin can be used in the diagnosis of GDM or for diagnostic purposes in high-risk pregnancies, along with a review of other parameters that may be associated with serum asprosin levels.: Patients ... ...

    Abstract Purpose: This study sought to investigate whether asprosin can be used in the diagnosis of GDM or for diagnostic purposes in high-risk pregnancies, along with a review of other parameters that may be associated with serum asprosin levels.
    Patients and methods: The study investigated the association between gestational diabetes mellitus (GDM) and asprosin levels. A total of 93 participants; 30 patients with GDM, 33 healthy pregnant women with normal glucose tolerance (NGT), and 30 healthy non-diabetic women (control group) at the Endocrinology and Metabolic Diseases outpatient clinic of a tertiary care university hospital were enrolled in the study. Patients with GDM and NGT were examined in terms of GDM between the 24th and 28th week of pregnancy (2nd trimester). Patient data were collected during routine examinations, and asprosin levels were measured using the ELISA method. All participants underwent testing for measurements of serum hemoglobin, insulin, C-peptide, fasting plasma glucose, and glycated hemoglobin (HbA1c) levels following a fasting period of at least eight hours.
    Results: Asprosin levels were higher in pregnant women with NGT and with GDM versus controls (Control-NGT asprosin,
    Conclusion: Serum asprosin levels can potentially be used as a marker in the diagnosis of GDM.
    Language English
    Publishing date 2023-08-23
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494854-8
    ISSN 1178-7007
    ISSN 1178-7007
    DOI 10.2147/DMSO.S424651
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  4. Article ; Online: Taste and Smell Impairment in SARS-CoV-2 Recovers Early and Spontaneously: Experimental Data Strongly Linked to Clinical Data.

    Sayin, Ibrahim / Yazici, Zahide Mine

    ACS chemical neuroscience

    2020  Volume 11, Issue 14, Page(s) 2031–2033

    Abstract: A growing body of literature indicates that smell and taste impairment has frequently occurred during the Severe Acute Respiratory Syndrome (SARS)-like Coronavirus (SARS-CoV-2) outbreak. Experimental studies have mostly found that non-neural-type cells ... ...

    Abstract A growing body of literature indicates that smell and taste impairment has frequently occurred during the Severe Acute Respiratory Syndrome (SARS)-like Coronavirus (SARS-CoV-2) outbreak. Experimental studies have mostly found that non-neural-type cells are responsible for SARS-CoV-2-related taste and smell impairment. If this is the case, smell/taste impairment needs to recover early. Literature data from clinical studies indicated a strong correlation between experimental and clinical findings. This article presents clinical studies related to SARS-CoV-2-induced smell/taste impairment that reported recovery rates. Experimental researchers may use these data to observe the dynamics of smell impairment and implement these findings in their research (e.g., correct timing of sampling) to perform further studies.
    MeSH term(s) Betacoronavirus ; Brain ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Severe acute respiratory syndrome-related coronavirus ; SARS-CoV-2 ; Smell ; Taste
    Keywords covid19
    Language English
    Publishing date 2020-07-01
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 1948-7193
    ISSN (online) 1948-7193
    DOI 10.1021/acschemneuro.0c00296
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  5. Article ; Online: A Closed Chamber ENT Examination Unit for Aerosol-Generating Endoscopic Examinations of COVID-19 Patients.

    Sayin, İbrahim / Devecioğlu, İbrahim / Yazıcı, Zahide Mine

    Ear, nose, & throat journal

    2020  Volume 99, Issue 9, Page(s) 594–596

    MeSH term(s) Air Filters ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Endoscopy/instrumentation ; Endoscopy/methods ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Otorhinolaryngologic Surgical Procedures/instrumentation ; Otorhinolaryngologic Surgical Procedures/methods ; Pandemics/prevention & control ; Physical Examination/instrumentation ; Physical Examination/methods ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Ultraviolet Rays ; Ventilation
    Keywords covid19
    Language English
    Publishing date 2020-06-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/0145561320931216
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 107: Show issues Location:
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  6. Article ; Online: A Rare Sinonasal Malignancy: Biphenotypic Sinonasal Sarcoma.

    Aydın Sudabatmaz, Esra / Abakay, M Akif / Koçbıyık, Alper / Sayın, İbrahim / Yazıcı, Zahide Mine

    Turkish archives of otorhinolaryngology

    2022  Volume 60, Issue 1, Page(s) 53–58

    Abstract: Biphenotypic sinonasal sarcoma (BSNS), which has been described in the recent years, is a low-grade spindle cell sinonasal sarcoma characterized by rare neural and myogenic features. It has a slow growth pattern; does not metastasize, but local ... ...

    Abstract Biphenotypic sinonasal sarcoma (BSNS), which has been described in the recent years, is a low-grade spindle cell sinonasal sarcoma characterized by rare neural and myogenic features. It has a slow growth pattern; does not metastasize, but local recurrences are common after surgery. Non-specificity of examination findings and symptoms and similarities of its histopathological features with other spindle cell sarcomas, neural tumors, and skeletal muscle-derived tumors involving the nasal cavity make the diagnosis difficult. Therefore, histopathological features should be evaluated together with immunophenotyping and molecular studies for differential diagnosis. There are very few BSNS cases or case series in the literature. In this report, we reported our clinical approach to a case with BSNS in the right nasal cavity and the histopathological features of the disease in the light of the current literature.
    Language English
    Publishing date 2022-05-12
    Publishing country Turkey
    Document type Case Reports
    ISSN 2667-7474
    ISSN (online) 2667-7474
    DOI 10.4274/tao.2022.2021-11-9
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  7. Article ; Online: Local Nasal Response Against COVID-19: Debate Regarding the Absence of Nasal Inflammatory Symptoms.

    Sayin, Ibrahim / Yazici, Zahide Mine / Akgül, Ahmet

    Ear, nose, & throat journal

    2021  Volume 102, Issue 2, Page(s) NP82–NP83

    MeSH term(s) Humans ; COVID-19 ; Rhinitis, Allergic, Seasonal ; Nasal Mucosa
    Language English
    Publishing date 2021-02-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/0145561321992505
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A Closed Chamber ENT Examination Unit for Aerosol-Generating Endoscopic Examinations of COVID-19 Patients

    Sayin, İbrahim / Devecioğlu, İbrahim / Yazıcı, Zahide Mine

    Ear, Nose & Throat Journal

    2020  Volume 99, Issue 9, Page(s) 594–596

    Keywords Otorhinolaryngology ; covid19
    Language English
    Publisher SAGE Publications
    Publishing country us
    Document type Article ; Online
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/0145561320931216
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 107: Show issues Location:
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  10. Article ; Online: Taste and Smell Impairment in SARS-CoV-2 Recovers Early and Spontaneously

    Sayin, Ibrahim / Yazici, Zahide Mine

    ACS Chemical Neuroscience

    Experimental Data Strongly Linked to Clinical Data

    2020  Volume 11, Issue 14, Page(s) 2031–2033

    Keywords Cell Biology ; Biochemistry ; Physiology ; Cognitive Neuroscience ; General Medicine ; covid19
    Language English
    Publisher American Chemical Society (ACS)
    Publishing country us
    Document type Article ; Online
    ISSN 1948-7193
    DOI 10.1021/acschemneuro.0c00296
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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