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  1. Book ; Online: Atmospheric Pressure Plasma

    Nikiforov, Anton / Chen, Zhiqiang

    from Diagnostics to Applications

    2019  

    Keywords Plasma physics ; free radicals, microplasma, corona discharge, surface charge, plasma drug delivery, electron paramagnetic resonance
    Language English
    Size 1 electronic resource (144 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030647733
    ISBN 9781839621512 ; 1839621516
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: The Role of Specificity Protein 1 (SP1) in Bladder Cancer Progression through PTEN-Mediated AKT/mTOR Pathway.

    Chen, Zhiqiang

    Urologia internationalis

    2023  Volume 107, Issue 9, Page(s) 848–856

    Abstract: Introduction: The aim of the study was to investigate the potential mechanism of specificity protein 1 (SP1) in bladder cancer progression through the PTEN-mediated AKT/mTOR pathway.: Methods: Human bladder cancer cell lines (HT-1197, HT-1376, and ... ...

    Abstract Introduction: The aim of the study was to investigate the potential mechanism of specificity protein 1 (SP1) in bladder cancer progression through the PTEN-mediated AKT/mTOR pathway.
    Methods: Human bladder cancer cell lines (HT-1197, HT-1376, and T24) and normal ureteral epithelial cell line SV-HUC-1 were used. SP1 expression was detected via quantitative real-time PCR and Western blotting. Cell viability, migration, invasion, and apoptosis were assessed using CCK-8, transwell, and flow cytometry assays, respectively. The involvement of the PTEN-mediated AKT/mTOR pathway was evaluated by Western blot. A mouse xenograft model was built, and immunohistochemical staining was applied to visualize SP1 and Ki67 expression in tumor tissues.
    Results: SP1 was overexpressed in bladder cancer cells. SP1 knockdown inhibited viability, migration, and invasion and promoted apoptosis in bladder cancer cells. PTEN intervention increased cell viability, migration, and invasion and decreased apoptosis, which was reversed by SP1 knockdown. The activation of the AKT/mTOR pathway resulting from PTEN knockdown was attenuated by SP1 knockdown. In vivo results showed that SP1 knockdown suppressed tumor growth, increased PTEN expression, and decreased AKT/mTOR pathway-related protein levels.
    Conclusion: SP1 promotes bladder cancer progression by inhibiting the PTEN-mediated AKT/mTOR pathway. Targeting SP1 may be a potential therapeutic strategy for treating bladder cancer.
    MeSH term(s) Animals ; Humans ; Mice ; Apoptosis ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Proto-Oncogene Proteins c-akt ; PTEN Phosphohydrolase/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/metabolism ; Urinary Bladder Neoplasms/genetics
    Chemical Substances Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; PTEN Phosphohydrolase (EC 3.1.3.67) ; PTEN protein, human (EC 3.1.3.67) ; TOR Serine-Threonine Kinases (EC 2.7.11.1) ; SP1 protein, human
    Language English
    Publishing date 2023-09-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 204045-1
    ISSN 1423-0399 ; 0042-1138
    ISSN (online) 1423-0399
    ISSN 0042-1138
    DOI 10.1159/000532128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui VI Zs.180: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Crystallization of amorphous anodized TiO

    Wang, Zhiqiang / Chen, Kunfeng / Xue, Dongfeng

    RSC advances

    2024  Volume 14, Issue 12, Page(s) 8195–8203

    Abstract: ... Anodized ... ...

    Abstract Anodized TiO
    Language English
    Publishing date 2024-03-11
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d4ra00852a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cognitive Decline After S-Ketamine Use.

    Li, Mingguo / Yang, Yuanyuan / Zhao, Zhiqiang / Chen, Long / Pan, Zhenliang

    American journal of therapeutics

    2024  

    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1280786-2
    ISSN 1536-3686 ; 1075-2765
    ISSN (online) 1536-3686
    ISSN 1075-2765
    DOI 10.1097/MJT.0000000000001624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4351: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Cinematic rendering improves the AO/OTA classification of distal femur fractures compared to volume rendering: a retrospective single-center study.

    Chen, Song / Wang, Xiong / Zheng, Zhenxin / Fu, Zhiqiang

    Frontiers in bioengineering and biotechnology

    2024  Volume 11, Page(s) 1335759

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1335759
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Deletion of Nox from

    Li, Dezhi / Ma, Wenwen / Chen, Guowei / Huang, Zhiqiang / Liu, Qing

    Foodborne pathogens and disease

    2024  

    Abstract: The foodborne pathogens have a serious threat to human health, ... ...

    Abstract The foodborne pathogens have a serious threat to human health, especially
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2148479-X
    ISSN 1556-7125 ; 1535-3141
    ISSN (online) 1556-7125
    ISSN 1535-3141
    DOI 10.1089/fpd.2023.0125
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7517: Show issues

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  7. Article ; Online: Anti-Aging in

    Zhang, Xue / Chen, Qi / Chen, Linzhen / Chen, Xiaolu / Ma, Zhiqiang

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 6

    Abstract: Polygonatum ... ...

    Abstract Polygonatum cyrtonema
    MeSH term(s) Animals ; Caenorhabditis elegans/metabolism ; Antioxidants/pharmacology ; Antioxidants/metabolism ; Polygonatum ; Aging ; Polysaccharides/pharmacology ; Polysaccharides/metabolism ; Superoxide Dismutase/metabolism
    Chemical Substances Antioxidants ; Polysaccharides ; Superoxide Dismutase (EC 1.15.1.1)
    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29061276
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  8. Article: Polymorphs of Nb

    Pang, Rui / Wang, Zhiqiang / Li, Jinkai / Chen, Kunfeng

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 21

    Abstract: Niobium pentoxide ( ... ...

    Abstract Niobium pentoxide (Nb
    Language English
    Publishing date 2023-10-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16216956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effects of Fe/Fe-Mn oxides loaded biochar on anaerobic degradation of typical phenolic compounds in coal gasification wastewater: Performance and mechanism.

    Li, Da / Wen, Qinxue / Chen, Zhiqiang

    Bioresource technology

    2024  Volume 394, Page(s) 130308

    Abstract: In this study, two kinds of magnetic biochar (BC) were synthesized by loading Fe (FeBC) and Fe-Mn oxides (FMBC) and their effects on anaerobic phenolics degradation were investigated. Compared with BC/FMBC, FeBC addition achieved the superior phenolics ... ...

    Abstract In this study, two kinds of magnetic biochar (BC) were synthesized by loading Fe (FeBC) and Fe-Mn oxides (FMBC) and their effects on anaerobic phenolics degradation were investigated. Compared with BC/FMBC, FeBC addition achieved the superior phenolics biodegradation even for 3,5-xylenol. Compared with control, FeBC addition enhanced CH
    MeSH term(s) Wastewater ; Oxides ; Anaerobiosis ; Coal ; Charcoal ; Phenols
    Chemical Substances Wastewater ; Oxides ; biochar ; Coal ; Charcoal (16291-96-6) ; Phenols
    Language English
    Publishing date 2024-01-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2024.130308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 3258: Show issues

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  10. Book: Männliche und weibliche Unfruchtbarkeit

    Chen, Zhi-Qiang / Li, Li-Yun

    (Die klinische Praxis der Chinesischen Medizin)

    2013  

    Title variant Die klinische Praxis der Chinesischen Medizin - männliche und weibliche Unfruchtbarkeit
    Author's details Zhi-qiang Chen ; Li-yun Li
    Series title Die klinische Praxis der Chinesischen Medizin
    Keywords Infertility, Male ; Infertility, Female ; Medicine, Chinese Traditional / methods ; Sterilität ; Chinesische Medizin
    Subject Traditionelle chinesische Medizin ; TCM ; Infertilität ; Unfruchtbarkeit
    Subject code 616.692060951
    Language German ; Chinese
    Size 439 S., 24 cm
    Edition 1. dt. Aufl.
    Publisher Bacopa-Verl
    Publishing place Schiedlberg
    Publishing country Austria
    Document type Book
    Note Aus dem Engl. übers. ; Literaturangaben
    HBZ-ID HT017753939
    ISBN 978-3-901618-90-1 ; 3-901618-90-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 2122 available for loan (reading room) Lesesaal EG

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