LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 269

Search options

  1. Article ; Online: N-Heterocyclic Carbene-Catalyzed [3 + 3] Annulation of 5-Aminopyrazoles with Enals: Enantioselective Synthesis of Pyrazolo[3,4-

    Li, Jiahan / Duan, Xiao-Yong / Ren, Xiaojie / Li, Yanting / Qi, Jing

    The Journal of organic chemistry

    2023  Volume 88, Issue 23, Page(s) 16621–16632

    Abstract: An enantioselective construction of pyrazolo[3,4- ...

    Abstract An enantioselective construction of pyrazolo[3,4-
    Language English
    Publishing date 2023-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.3c00793
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: In situ formation of solidified supramolecular solvent based dispersive liquid-liquid microextraction for the enrichment of phenylurea herbicides in water, fruit juice, and milk.

    Chen, Shurong / Jiang, Yuhao / Li, Junxian / You, Meng / Zhang, Rongxu / Li, Jilong / Fu, Zhuang / Xie, Jiahan / Wang, Zhibing

    Food chemistry

    2024  Volume 450, Page(s) 139298

    Abstract: A convenient, efficient, and green dispersive liquid-liquid microextraction based on the in situ formation of solidified supramolecular solvents combined with high performance liquid chromatography was developed for the determination of four phenylurea ... ...

    Abstract A convenient, efficient, and green dispersive liquid-liquid microextraction based on the in situ formation of solidified supramolecular solvents combined with high performance liquid chromatography was developed for the determination of four phenylurea herbicides in liquid samples, including monuron, monolinuron, isoproturon, and chlortoluron. Herein, a novel supramolecular solvent was prepared by the in situ reaction of [P
    Language English
    Publishing date 2024-04-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2024.139298
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 3634: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Correlation between PD-L1 expression status and efficacy of immunotherapy as second-line or later-line therapy in advanced non-small cell lung cancer patients.

    Liu, Jingya / Man, Yingchun / Gao, Jianing / Wang, Xinxin / Zhang, Lijie / Li, Mingheng / Yu, Jiahan

    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)

    2024  

    Abstract: Objective: The objective of this study is to evaluate the correlation between tumor proportionality scores (TPS) and the effectiveness of immune checkpoint inhibitors (ICIs) as the second or subsequent line therapies for individuals who received ... ...

    Abstract Objective: The objective of this study is to evaluate the correlation between tumor proportionality scores (TPS) and the effectiveness of immune checkpoint inhibitors (ICIs) as the second or subsequent line therapies for individuals who received diagnoses of advanced non-small cell lung cancer (NSCLC).
    Methods: The retrospective analysis was conducted on the medical records of a total of 143 patients who received diagnoses of stage IIIB/IV NSCLC and were admitted to our hospital from the beginning of 2019 to the end of September 2022. The follow-up period ended on 01 January 2023. The study used Kaplan-Meier survival curves to assess the progression-free survival (PFS) and overall survival (OS) of patients. Univariate and multivariate Cox proportional risk models were used to analyze the factors associated with the PFS and OS of advanced-stage NSCLC patients who received ICIs as the second or subsequent lines.
    Results: Patients diagnosed with NSCLC who had a TPS ≥1% and got treatment with ICIs exhibit notably elevated rates of partial response, objective response rate, disease control rate and extended PFS in comparison to NSCLC patients with a TPS of <1% (P < 0.05). NSCLC patients with TPS within 1-49% [hazard ratio (HR) = 0.372; 95% confidence interval (CI), 0.140-0.993; P = 0.048] or ≥50% (HR = 0.276; 95% CI, 0.095-0.796; P = 0.017) were significantly associated with prolonged PFS, which were conducted by multivariate Cox regression analysis.
    Conclusion: Programmed death protein-1 expression status may be predictive markers of the effectiveness of ICIs as the second or subsequent lines of therapies in advanced NSCLC are influenced by TPS.
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1137033-6
    ISSN 1473-5709 ; 0959-8278
    ISSN (online) 1473-5709
    ISSN 0959-8278
    DOI 10.1097/CEJ.0000000000000880
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3621: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: pH Effect on the Structure, Rheology, and Electrospinning of Maize Zein.

    Wu, Yuehan / Du, Jinhui / Zhang, Jiahan / Li, Yanlei / Gao, Zhiming

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 7

    Abstract: As a simple and convenient technology to fabricate micron-to-nanoscale fibers with controllable structure, electrostatic spinning has produced fiber films with many natural advantages, including a large specific surface area and high porosity. Maize zein, ...

    Abstract As a simple and convenient technology to fabricate micron-to-nanoscale fibers with controllable structure, electrostatic spinning has produced fiber films with many natural advantages, including a large specific surface area and high porosity. Maize zein, as a major storage protein in corn, showed high hydrophobicity and has been successfully applied as a promising carrier for encapsulation and controlled release in the pharmaceutical and food areas. Proteins exhibit different physical and chemical properties at different pH values, and it is worth investigating whether this change in physical and chemical properties affects the properties of electrospun fiber films. We studied the pH effects on zein solution rheology, fiber morphology, and film properties. Rotational rheometers were used to test the rheology of the solutions and establish a correlation between solution concentration and fiber morphology. The critical concentrations calculated by the cross-equation fitting model were 17.6%, 20.1%, 20.1%, 17.1%, and 19.5% (
    Language English
    Publishing date 2023-03-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12071395
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Atroposelective Access to Dihydropyridinones with C-N Axial and Point Chirality via NHC-Catalyzed [3 + 3] Annulation.

    Li, Yanting / Duan, Xiao-Yong / Yang, Chengxian / Wei, Yamei / Li, Jiahan / Ren, Xiaojie / Qi, Jing

    The Journal of organic chemistry

    2023  Volume 88, Issue 15, Page(s) 11299–11309

    Abstract: ... ...

    Abstract An
    Language English
    Publishing date 2023-07-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.3c00854
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4473: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Characteristics and reduction assessment of GHG emissions from crop residue open burning in China under the targets of carbon peak and carbon neutrality.

    Wu, Bobo / Li, Jiahan / Yao, Zhiliang / Li, Xin / Wang, Weijun / Wu, Zichun / Zhou, Qi

    The Science of the total environment

    2023  Volume 905, Page(s) 167235

    Abstract: Driven by the goal of carbon peak and carbon neutrality, greenhouse gas (GHG) emissions from the crop residue open burning (CROB) in China cannot be ignored. In this study, we have established a high-resolution (0.05° × 0.05°) GHG emissions inventory ( ... ...

    Abstract Driven by the goal of carbon peak and carbon neutrality, greenhouse gas (GHG) emissions from the crop residue open burning (CROB) in China cannot be ignored. In this study, we have established a high-resolution (0.05° × 0.05°) GHG emissions inventory (including CO
    Language English
    Publishing date 2023-09-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.167235
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Highly Enantioselective Construction of the Polycyclic Piperazin-2-ones via NHC-Catalyzed [12 + 2] Cycloadditions.

    Ren, Xiaojie / Duan, Xiao-Yong / Li, Yanting / Li, Jiahan / Qi, Jing

    Organic letters

    2023  Volume 25, Issue 43, Page(s) 7917–7922

    Abstract: NHC-catalyzed diastereoselective and enantioselective [12 + 2] higher-order cycloadditions of 5H-benzo[a]-pyrrolizine-3-carbaldehydes with cyclic sulfonic imines are described. Various optically pure polycyclic piperazin-2-ones were successfully ... ...

    Abstract NHC-catalyzed diastereoselective and enantioselective [12 + 2] higher-order cycloadditions of 5H-benzo[a]-pyrrolizine-3-carbaldehydes with cyclic sulfonic imines are described. Various optically pure polycyclic piperazin-2-ones were successfully constructed under mild reaction conditions with excellent diastereoselectivities and enantioselectivities. The generated chiral polycyclic piperazin-2-ones could be transformed to planar-chiral nine-membered cyclic amides via squaramide-catalyzed asymmetric ring-expansion reactions.
    Language English
    Publishing date 2023-10-24
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.3c03171
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Oleic acid triggers burial behavior in a termite population through an odorant binding protein.

    Li, Hongyue / Liu, Jiahan / Wang, Qian / Ma, Yuanfei / Zhao, Weisong / Chen, Bosheng / Price, Jennifer Hackney / Zhang, Dayu

    Insect biochemistry and molecular biology

    2024  Volume 167, Page(s) 104090

    Abstract: Social insects maintain hygienic conditions through their social immunity behaviors. Among these behaviors, burial behavior of termites is central for protecting healthy individuals from corpses. Many factors trigger burial behavior, and it is generally ... ...

    Abstract Social insects maintain hygienic conditions through their social immunity behaviors. Among these behaviors, burial behavior of termites is central for protecting healthy individuals from corpses. Many factors trigger burial behavior, and it is generally believed that chemicals released by corpses, such as oleic acid, are the most important cues for triggering burial behavior in termites. However, the contribution of the olfactory system to this behavior remains unclear. Here we report an odorant binding protein (OBP) that transports oleic acid and triggers burial behavior in Coptotermes formosanus Shiraki. We demonstrated that CforOBP7 is highly expressed in the antennae of workers. Fluorescent competition binding experiments exhibited that CforOBP7 has a strong affinity for oleic acid. Furthermore, the antennal response to oleic acid was significantly reduced, and oleic acid-triggered burial behavior was also inhibited in CforOBP7-silenced termites. We conclude that CforOBP7 governs the burial behavior of C. formosanus triggered by oleic acid.
    MeSH term(s) Humans ; Animals ; Isoptera ; Oleic Acid ; Odorants ; Cadaver ; Burial
    Chemical Substances Oleic Acid (2UMI9U37CP)
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1483248-3
    ISSN 1879-0240 ; 0965-1748
    ISSN (online) 1879-0240
    ISSN 0965-1748
    DOI 10.1016/j.ibmb.2024.104090
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Cirques of the Southeastern Tibetan Plateau and Their Links to Climatic and Non-Climatic Factors.

    Li, Shengxian / Zhang, Qian / Wang, Jiahan

    International journal of environmental research and public health

    2022  Volume 19, Issue 20

    Abstract: Cirque morphology is used to reflect the patterns of paleoclimate, paleoglaciation, and landscape evolution. Cirque study has been conducted in the Gangdise Mountains of the southern Tibetan Plateau (TP) and the central TP (dominated by a weak Indian ... ...

    Abstract Cirque morphology is used to reflect the patterns of paleoclimate, paleoglaciation, and landscape evolution. Cirque study has been conducted in the Gangdise Mountains of the southern Tibetan Plateau (TP) and the central TP (dominated by a weak Indian summer monsoon (ISM) or a continental climate). This study focused on the cirques in the southeastern TP, which is dominated by a strong ISM, to analyse the controlling factors on cirque morphology. A total of 361 cirques were mapped in the Taniantaweng Range of the southeastern TP, and their metrics were calculated. The results showed that the cirque sizes increased with temperature and decreased with precipitation, which may be due to the development of valley-type glaciers and the effect of non-climatic factors. The cirques tended to face NE, implying that they prefer leeward slopes, and they were under the 'morning-afternoon' effect. With altitude, the tendency of the cirque aspect shifted from N to SE, and the cirque size decreased. The former may indicate the ability of the high altitude to support cirque development on climatically unfavourable slopes; the latter may be due to the development of valley-type glaciers or insufficient space for cirque development. The cirque size and shape did not show statistical differences between aspects. The cirques on soft bedrocks had larger heights than those on hard bedrocks, indicating that soft bedrocks promote subglacial erosion. A comparison with the results of the western, central, and eastern sectors of the Gangdise Mountains and the central TP reveals that the strength of the ISM did not necessarily increase the cirque density but limited the cirque size on a regional scale. The CFA did not show a reverse relationship with precipitation, but it showed a positive correlation with the cirque Z
    MeSH term(s) Tibet ; Ice Cover ; Seasons ; Altitude ; Temperature
    Language English
    Publishing date 2022-10-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph192013104
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: The complete chloroplast genome sequence of

    Liu, Jiahan / Wang, Zhen / Ren, Weichao / Liu, Chi / Li, XiangQuan / Han, Jiayong / Ma, Wei

    Mitochondrial DNA. Part B, Resources

    2022  Volume 7, Issue 6, Page(s) 1030–1031

    Abstract: Dictamnus albus L. ...

    Abstract Dictamnus albus L.
    Language English
    Publishing date 2022-06-14
    Publishing country England
    Document type Journal Article
    ISSN 2380-2359
    ISSN (online) 2380-2359
    DOI 10.1080/23802359.2022.2081097
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top