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  1. Article: Submassive Pulmonary Embolism Treated With Catheter-Directed Thrombolysis in Resource-Limited Setting: A Case Report and Review of Literature.

    Gurjar, Hitesh / Singh, Himani / Gurjar, Barkha

    Cureus

    2022  Volume 14, Issue 1, Page(s) e21760

    Abstract: We describe a case of a young male who presented with acute onset progressively worsening shortness of breath for four days duration. He used to smoke cigarettes, and his profession required prolonged periods of standing. He underwent a two-dimensional ... ...

    Abstract We describe a case of a young male who presented with acute onset progressively worsening shortness of breath for four days duration. He used to smoke cigarettes, and his profession required prolonged periods of standing. He underwent a two-dimensional echocardiogram showing right ventricular (RV) strain and computed tomography (CT) showing thrombus in the left major pulmonary artery. His pulmonary embolism severity index (PESI) score was high, predicting higher short-term mortality. Treatment options including risks and benefits were discussed with the patient, and he underwent catheter-directed thrombolysis (CDT) with rapid resolution of symptoms, oxygen saturation, and pulmonary artery pressures (PAP). He was discharged home safely after successful treatment of his condition.
    Language English
    Publishing date 2022-01-31
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.21760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Tadpole Sign in Filum Terminale Paragangliomas.

    Dharanipathy, Sundarakrishnan / Gurjar, Hitesh / Kumar, Amandeep

    World neurosurgery

    2023  Volume 175, Page(s) 76–77

    Abstract: Two normotensive male patients came with complaints of low back pain. Contrast-enhanced magnetic resonance imaging of the lumbosacral spine revealed an enhancing intradural extramedullary lesion (at the L4-L5 vertebral level in the first patient and at ... ...

    Abstract Two normotensive male patients came with complaints of low back pain. Contrast-enhanced magnetic resonance imaging of the lumbosacral spine revealed an enhancing intradural extramedullary lesion (at the L4-L5 vertebral level in the first patient and at the L2-L3 vertebral level in the second patient). The tumor resembled the head and caudal blood vessels the tail of a tadpole, thereby giving the "tadpole sign." This sign is an important radiologic and histopathologic correlate, which is helpful in preoperative diagnosis of spinal paraganglioma.
    MeSH term(s) Humans ; Male ; Cauda Equina/diagnostic imaging ; Cauda Equina/surgery ; Cauda Equina/pathology ; Spine/pathology ; Magnetic Resonance Imaging ; Low Back Pain/pathology ; Paraganglioma/diagnostic imaging ; Paraganglioma/surgery ; Paraganglioma/pathology
    Language English
    Publishing date 2023-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.03.133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Complete resolution of syrinx after circumferential adhesiolysis without deformity correction in a case of 6 year old neglected cervical facet dislocation.

    Gurjar, Hitesh / Abhilash Reddy, D / Tungish, Bansal

    Journal of clinical orthopaedics and trauma

    2023  Volume 38, Page(s) 102126

    Abstract: Neglected traumatic cervical dislocation can be difficult to treat as such and more so if they are accompanied by an associated post traumatic syringomyelia (PTS). We present the case of a 55 year old gentleman who had a traumatic C6-C7 grade 2 listhesis ...

    Abstract Neglected traumatic cervical dislocation can be difficult to treat as such and more so if they are accompanied by an associated post traumatic syringomyelia (PTS). We present the case of a 55 year old gentleman who had a traumatic C6-C7 grade 2 listhesis which was neglected and presented 6 year later with 6 months history of neck pain, spastic quadriparesis and bowel bladder involvement. The patient was diagnosed with a PTS extending from C4 to D5. The possible aetiology and management of such cases has been discussed. The patient was successfully treated with decompression, adhesiolysis of arachnoid bands and syringotomy without the correction of deformity. The patient improved neurologically and had complete resolution of syrinx at final followup.
    Language English
    Publishing date 2023-02-12
    Publishing country India
    Document type Case Reports
    ZDB-ID 2596956-0
    ISSN 2213-3445 ; 0976-5662
    ISSN (online) 2213-3445
    ISSN 0976-5662
    DOI 10.1016/j.jcot.2023.102126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A Reversible Cause of Cutaneous Rash in a Patient With Alcohol Consumption.

    Haider, Asim / Gurjar, Hitesh / Ghazanfar, Haider / Singh, Himani / Siddiqa, Ayesha

    Cureus

    2023  Volume 15, Issue 2, Page(s) e35011

    Abstract: The most common cutaneous manifestations of alcoholism include urticarial reaction, flushing, porphyria cutanea tarda, psoriasis, rosacea, seborrheic dermatitis, and pruritus. Here, we present a case of a young male with a history of alcohol abuse who ... ...

    Abstract The most common cutaneous manifestations of alcoholism include urticarial reaction, flushing, porphyria cutanea tarda, psoriasis, rosacea, seborrheic dermatitis, and pruritus. Here, we present a case of a young male with a history of alcohol abuse who presented with non-blanching, petechial, and perifollicular macular rash secondary to vitamin C deficiency in view of poor oral intake. The rash improved significantly with vitamin C supplementation. Although rare in developed countries, clinicians should keep vitamin C deficiency as a differential diagnosis for skin rash in alcohol consumers.
    Language English
    Publishing date 2023-02-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.35011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Necrotizing Fasciitis In A Patient with Metastatic Clear Cell Ovarian Carcinoma Treated with Bevacizumab.

    Haider, Asim / Gurjar, Hitesh / Ghazanfar, Haider / Chilimuri, Sridhar

    The American journal of case reports

    2022  Volume 23, Page(s) e935584

    Abstract: BACKGROUND Necrotizing fasciitis is a life-threatening infection of the deep soft tissues that leads to progressive destruction of the fascia and subcutaneous fat. It typically spreads along the muscle fascia planes because of the relatively poor blood ... ...

    Abstract BACKGROUND Necrotizing fasciitis is a life-threatening infection of the deep soft tissues that leads to progressive destruction of the fascia and subcutaneous fat. It typically spreads along the muscle fascia planes because of the relatively poor blood supply. Muscle tissue is usually spared because of its better blood supply. The usual risk factors for necrotizing fasciitis include trauma, malnutrition, obesity, uncontrolled diabetes mellitus, alcoholism, cirrhosis, neutropenia, and recent surgery. CASE REPORT We present a case of a middle-aged female who presented with necrotizing fasciitis of the right gluteal region. Her medical history was significant for well-controlled diabetes mellitus (hemoglobin A1c: 6.6), and clear cell carcinoma of ovaries (stage IV). She was on active chemotherapy with bevacizumab, paclitaxel, and carboplatin. She underwent incision and debridement of right gluteal abscess with drainage of 200 ml of foul-smelling pus and was started on intravenous antibiotics. Her blood cultures were negative, but the cultures taken from the right gluteal abscess showed moderate growth of Escherichia coli. The antibiotics were de-escalated and the patient was discharged with outpatient follow-up. CONCLUSIONS Bevacizumab, a humanized monoclonal IgG antibody, is a novel treatment for metastatic ovarian cancer. It is associated with necrotizing fasciitis due to anti-angiogenic, pro-thrombotic, and poor wound healing properties. It should be stopped in the patients presenting with necrotizing fasciitis.
    MeSH term(s) Abscess/drug therapy ; Anti-Bacterial Agents/therapeutic use ; Antibodies, Monoclonal, Humanized ; Bevacizumab/therapeutic use ; Fasciitis, Necrotizing/drug therapy ; Female ; Humans ; Middle Aged ; Ovarian Neoplasms/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Antibodies, Monoclonal, Humanized ; Bevacizumab (2S9ZZM9Q9V)
    Language English
    Publishing date 2022-06-25
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.935584
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Technical Considerations in Surgical Fixation of Jefferson Fracture

    Gurjar, Hitesh Kumar / Rai, Hitesh Inder Singh / Mishra, Shashwat / Garg, Kanwaljeet

    Indian Journal of Neurotrauma

    2022  Volume 20, Issue 02, Page(s) 140–147

    Abstract: Jefferson fracture is defined as the simultaneous disruption of the continuity of the anterior and posterior arches of the atlas vertebra. It generally results from an axial impact to the head. Most of these fractures are amenable to nonoperative ... ...

    Abstract Jefferson fracture is defined as the simultaneous disruption of the continuity of the anterior and posterior arches of the atlas vertebra. It generally results from an axial impact to the head. Most of these fractures are amenable to nonoperative management. Significant disruption of the transverse atlantal ligament that is the main stabilizing ligament of the atlantoaxial articulation and contiguous spinal injuries often form the indications for operative intervention in these fractures. The outward and caudal displacement of the C1 lateral masses observed in these fractures often requires significant deviation from the standard operative technique of atlantoaxial fixation when the osseous elements are intact. Accordingly, we have described the surgical nuances relevant to the exposure and instrumentation of the atlantoaxial region in the setting of Jefferson fracture, through our experience in two cases.
    Keywords atlantoaxial fractures ; biomechanics ; Jefferson fracture ; lateral displacement ; rule of spence ; transverse atlantal ligament
    Language English
    Publishing date 2022-12-27
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2266738-6
    ISSN 2213-3739 ; 0973-0508 ; 2213-3739
    ISSN (online) 2213-3739
    ISSN 0973-0508 ; 2213-3739
    DOI 10.1055/s-0042-1759854
    Database Thieme publisher's database

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  7. Article ; Online: Transcranial Surgery for Pituitary Tumors: A "Community Neurosurgery Experience".

    Mishra, Shashwat / Mishra, Ramesh C / Gurjar, Hitesh K / Garg, Kanwaljeet

    Neurology India

    2022  Volume 70, Issue 5, Page(s) 2039–2046

    Abstract: Background: Despite the evolution of endoscopic techniques, large pituitary adenomas with unfavorable characteristics and irregular anatomical configurations continue to pose a challenge for the dexterity, skills, and patience of endoscopic surgeons. ... ...

    Abstract Background: Despite the evolution of endoscopic techniques, large pituitary adenomas with unfavorable characteristics and irregular anatomical configurations continue to pose a challenge for the dexterity, skills, and patience of endoscopic surgeons. Transcranial surgery retains a significant role in these situations where the tumor access, hemostasis, and dissection around adjoining neurovascular tissues can be controlled efficaciously.
    Objective: In this report, we describe our experience with transcranial surgery for pituitary adenomas highlighting its safety and versatility in peripheral centers.
    Methods: We accessed the case files and imaging records of pituitary tumors operated between 2001 and 2019 at a private hospital in a major Indian city. The records were analyzed with emphasis on postoperative clinical course, visual, and endocrinological outcomes. The data was analyzed with respect to differences between transcranial and transsphenoidal procedures. Categorical variables were compared with Chi-square test/Fischer's exact test and difference in means evaluated with Welch's t-test.
    Results: A total of 178 procedures were performed in 173 patients with pituitary adenoma, who were the subjects of this study. Ninety-eight (56.7%) patients were treated by transsphenoidal excision whereas 80 (46.2%) underwent transcranial procedures (75 primary and five secondary). In the patients operated transcranially, we observed three deaths and nine patients suffered from significant morbidity. Visual outcomes were similar to the group operated transsphenoidally. However, incidence of panhypopituitarism was significantly higher in transcranial procedures; the extent of resection was poorer than transsphenoidal surgeries owing to more extensive nature of tumors.
    Conclusions: In low-volume centers, the endoscopic skills required for transsphenoidal resection of large and complex pituitary adenomas may be scarce. Transcranial surgery, dependent on familiar microsurgical techniques and equipment, may still be viable, safe, and an effective option.
    MeSH term(s) Humans ; Pituitary Neoplasms/surgery ; Pituitary Neoplasms/pathology ; Neurosurgery ; Sphenoid Bone/surgery ; Microsurgery/methods ; Treatment Outcome ; Retrospective Studies ; Adenoma/surgery ; Adenoma/pathology
    Language English
    Publishing date 2022-11-09
    Publishing country India
    Document type Journal Article
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.359173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Rare Case of Coronavirus Disease 2019 Vaccine-Associated Cerebral Venous Sinus Thrombosis Treated with Mechanical Thrombectomy.

    Gurjar, Hitesh / Dhallu, Manjeet / Lvovsky, Dmitry / Sadullah, Samiyah / Chilimuri, Sridhar

    The American journal of case reports

    2022  Volume 23, Page(s) e935355

    Abstract: BACKGROUND Vaccine-related thrombosis and thrombocytopenia syndrome (TTS) is a rare life-threatening syndrome reported after vaccination against COVID-19. CASE REPORT We describe a case of 56-year-old postmenopausal, obese woman with hypothyroidism and ... ...

    Abstract BACKGROUND Vaccine-related thrombosis and thrombocytopenia syndrome (TTS) is a rare life-threatening syndrome reported after vaccination against COVID-19. CASE REPORT We describe a case of 56-year-old postmenopausal, obese woman with hypothyroidism and hyperlipidemia, who presented to the Emergency Department (ED) with fluctuating mental status and left-side weakness for 5 days. She received her first and second dose of mRNA-1273 vaccine (Moderna) at 12 and 8 weeks, respectively, prior to presentation. She was found to have multiple hemorrhages and infarcts on a computed tomography (CT) scan of the head. She was intubated in the ED for airway protection and mechanically ventilated. Magnetic resonance angiogram and venogram showed multiple infarcts in right frontal, parietal, and left parietal lobes, along with occlusion of left-side transverse sinus, sagittal sinuses, and left internal jugular vein, suggesting cerebral venous sinus thrombosis (CVST). Despite anticoagulation, her clinical condition continued to worsen, and she was referred for emergent endovascular thrombectomy. Her clinical condition improved after thrombectomy, and she was discharged on warfarin. At 4-month follow-up, she was able to walk with an assistive device and able to carry out activities of daily living with assistance. She is planned for further work-up for hypercoagulable state at follow-up. CONCLUSIONS This case highlights the occurrence of vaccine-related thrombosis 3 months after vaccine administration. Only 2 cases of TTS have been reported so far after mRNA-1273 vaccination (Moderna). To the best of our knowledge, this is the first reported case of CVST presenting 3 months after the first dose of COVID-19 mRNA-1273 vaccine (Moderna).
    MeSH term(s) 2019-nCoV Vaccine mRNA-1273 ; Activities of Daily Living ; COVID-19 ; COVID-19 Vaccines ; Female ; Humans ; Middle Aged ; SARS-CoV-2 ; Sinus Thrombosis, Intracranial/complications ; Sinus Thrombosis, Intracranial/etiology ; Thrombectomy/methods
    Chemical Substances COVID-19 Vaccines ; 2019-nCoV Vaccine mRNA-1273 (EPK39PL4R4)
    Language English
    Publishing date 2022-02-19
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.935355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Atlanto-occipital assimilation: embryological basis and its clinical significance.

    Hanusun N, Hari Hara / Singh, Akanksha / Poddar, Pooja / J P, Jessy / Rani, Neerja / Gurjar, Hitesh / Singh, Seema

    Anatomy & cell biology

    2023  Volume 57, Issue 1, Page(s) 147–151

    Abstract: Atlanto-occipital assimilation is an osseous embryological anomaly of the craniovertebral junction in which the atlas (C1) is fused to the occiput of skull. Embryologically, this assimilation may happen due to failure of the segmentation and separation ... ...

    Abstract Atlanto-occipital assimilation is an osseous embryological anomaly of the craniovertebral junction in which the atlas (C1) is fused to the occiput of skull. Embryologically, this assimilation may happen due to failure of the segmentation and separation of the caudal occipital and the cranial cervical sclerotome. The segmentation clock is maintained by NOTCH and WNT signalling pathways along with
    Language English
    Publishing date 2023-12-20
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 2590173-4
    ISSN 2093-3673 ; 2093-3665
    ISSN (online) 2093-3673
    ISSN 2093-3665
    DOI 10.5115/acb.23.225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Re-Expansion Pulmonary Edema (RPE) in a Neurosurgical Patient.

    Meena, Rajesh Kumar / Gurjar, Hitesh K / Doddamani, Ramesh S / Narula, Dipanshu / Agrawal, Deepak / Chandra, P Sarat

    Neurology India

    2021  Volume 69, Issue 3, Page(s) 755–756

    MeSH term(s) Humans ; Pulmonary Edema/etiology
    Language English
    Publishing date 2021-06-25
    Publishing country India
    Document type Letter
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.319230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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