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  1. Article ; Online: A Low-cost Solution for Retro-fitment of HEPA Filter in Healthcare Facilities Providing Care to COVID-19 Patients.

    Malhotra, Vikas

    Indian pediatrics

    2020  Volume 57, Issue 5, Page(s) 477

    MeSH term(s) Air Conditioning/economics ; Air Conditioning/instrumentation ; Air Conditioning/methods ; Air Filters/economics ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Cost-Benefit Analysis ; Developing Countries ; Health Facilities ; Health Personnel ; Humans ; India ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Occupational Health ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-11
    Publishing country India
    Document type Letter
    ZDB-ID 402594-5
    ISSN 0974-7559 ; 0019-6061
    ISSN (online) 0974-7559
    ISSN 0019-6061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Low-cost Solution for Retrofitment of HEPA Filter in Healthcare Facilities Providing Care to COVID-19 Patients

    Malhotra, Vikas

    Indian Pediatrics

    2020  Volume 57, Issue 5, Page(s) 477–477

    Keywords Pediatrics, Perinatology, and Child Health ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 402594-5
    ISSN 0019-6061
    ISSN 0019-6061
    DOI 10.1007/s13312-020-1830-x
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Chronic Alcohol Use Associated Encephalopathy With a Nearly Identical Presentation to Normal Pressure Hydrocephalus.

    Patel, Shreya / Malhotra, Vasu / Scwartz, Shani / Smith, Travis / Malhotra, Vikas

    Cureus

    2023  Volume 15, Issue 5, Page(s) e38977

    Abstract: We present the case of a 52-year-old male who arrived at the Emergency Department after several ground-level falls in the past month. He complained of urinary incontinence, mild confusion, headaches, and appetite loss in the past month as well. Brain ... ...

    Abstract We present the case of a 52-year-old male who arrived at the Emergency Department after several ground-level falls in the past month. He complained of urinary incontinence, mild confusion, headaches, and appetite loss in the past month as well. Brain computed tomography (CT) and magnetic resonance imaging (MRI) were performed, which showed enlarged ventricles with moderately prominent cortical atrophy and no acute abnormalities. It was decided to conduct a cisternogram study with serial scans. The study showed a type IIIa cerebrospinal fluid (CSF) flow pattern at 24 hours. At the 48- and 72-hour marks, the study displayed an absence of radiotracer activity within the ventricles, while all the activity was concentrated within the cerebral cortices. These findings successfully ruled out normal pressure hydrocephalus (NPH) due to the highly specific indication of normal CSF circulation pattern. The patient was treated with thiamine and advised to quit drinking, as well as return for follow-up in one month as an outpatient for a repeat brain CT.
    Language English
    Publishing date 2023-05-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.38977
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Electrocardiogram Signals Denoising Using Improved Variational Mode Decomposition.

    Malhotra, Vikas / Sandhu, Mandeep Kaur

    Journal of medical signals and sensors

    2021  Volume 11, Issue 2, Page(s) 100–107

    Abstract: Background: Electrocardiogram (ECG) plays a vital role in the analysis of heart activity. It can be used to analyze the different heart diseases and mental stress assessment also. Various noises, such as baseline wandering, muscle artifacts and power ... ...

    Abstract Background: Electrocardiogram (ECG) plays a vital role in the analysis of heart activity. It can be used to analyze the different heart diseases and mental stress assessment also. Various noises, such as baseline wandering, muscle artifacts and power line interface disturbs the information within the ECG signal. To acquire correct information from ECG signal, these noises should be removed.
    Methods: In the proposed work, the improved variational mode decomposition (IVMD) method for the removal of noise in ECG signals is used. In the proposed method, the weighted signal amplitude integrated over the timeframe of the ECG signal varies the window size during decomposition. Raw ECG data are extracted from 10 subjects and ECG data are also taken from the MIT BIH database for the proposed method.
    Results: The performance comparison of traditional variational mode decomposition (VMD) and the proposed technique is also calculated using mean square error, percentage root mean square difference, signal to noise ratio and correlation coefficient. The extracted highest signal to noise ratio (SNR) value of acquired ECG signals using traditional VMD is 42db whereas highest value of signal to noise ratio (SNR) using improved VMD (IVMD) is 83db.
    Conclusion: The proposed IVMD technique represented better performance than traditional VMD for denoising of ECG signals.
    Language English
    Publishing date 2021-05-24
    Publishing country India
    Document type Journal Article
    ZDB-ID 2651622-6
    ISSN 2228-7477
    ISSN 2228-7477
    DOI 10.4103/jmss.JMSS_17_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Ellis van creveld syndrome: Cardiac anomalies and anesthetic implications.

    Guha, Amrita / Malhotra, Rohit / Saxena, Rachit / Keshri, Vikas K

    Annals of cardiac anaesthesia

    2023  Volume 26, Issue 3, Page(s) 346–348

    Abstract: Ellis-Van Creveld syndrome (EVC), also known as mesoectodermal dysplasia, is a rare autosomal recessive disorder with a tetrad of clinical features, comprising dwarfism, polydactyly, ectodermal dysplasia with sparse hair, hypoplastic nails and enamel, ... ...

    Abstract Ellis-Van Creveld syndrome (EVC), also known as mesoectodermal dysplasia, is a rare autosomal recessive disorder with a tetrad of clinical features, comprising dwarfism, polydactyly, ectodermal dysplasia with sparse hair, hypoplastic nails and enamel, hypodontia and conical teeth and congenital heart disease (CHD). We report an 18-year-old girl with short stature and polydactyly, who got admitted to our hospital with shortness of breath on exertion for the last 2 years. On echocardiography, a partial atrioventricular canal (AV canal) defect was diagnosed, which was repaired surgically. The patient had an uneventful perioperative period.
    MeSH term(s) Female ; Humans ; Adolescent ; Ellis-Van Creveld Syndrome/complications ; Ellis-Van Creveld Syndrome/diagnostic imaging ; Ellis-Van Creveld Syndrome/surgery ; Heart Defects, Congenital/complications ; Heart Defects, Congenital/diagnostic imaging ; Heart Defects, Congenital/surgery ; Polydactyly ; Anesthetics
    Chemical Substances Anesthetics
    Language English
    Publishing date 2023-07-20
    Publishing country India
    Document type Case Reports
    ZDB-ID 2106866-5
    ISSN 0974-5181 ; 0971-9784
    ISSN (online) 0974-5181
    ISSN 0971-9784
    DOI 10.4103/aca.aca_166_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Sensorineural Hearing Loss in Unilateral Mucosal Type of Chronic Otitis Media.

    Soni, Sanjay / Malhotra, Vikas / Sharma, Raman / Passey, J C

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2023  Volume 75, Issue 3, Page(s) 2149–2154

    Abstract: Sensorineural hearing loss is relatively well established in the squamosal chronic otitis media. However, its association with mucosal COM is still debated. The present study aimed at evaluating the prevalence of sensorineural hearing loss in unilateral ... ...

    Abstract Sensorineural hearing loss is relatively well established in the squamosal chronic otitis media. However, its association with mucosal COM is still debated. The present study aimed at evaluating the prevalence of sensorineural hearing loss in unilateral mucosal COM. The study was conducted at a tertiary care hospital in New Delhi, and 60 patients with unilateral mucosal chronic otitis media were recruited. Pure tone thresholds were ascertained for air and bone conduction in an acoustically treated room and matched against certain patient and disease characteristics. In this study, the combined prevalence of SNHL/Mixed Hearing loss in mucosal COM was found to be 8.3%. A statistically significant association between SNHL/Mixed HL was seen in the 40-50-year age group (
    Language English
    Publishing date 2023-05-03
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-023-03759-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: "Face of a Giant Panda" and "Beating Wings" in a Young Male.

    Arora, Navneet / Wasti, Kushal / Suri, Vikas / Malhotra, Pankaj

    Cureus

    2022  Volume 14, Issue 2, Page(s) e22429

    Abstract: Mutations in the gene coding for ATPase copper transporting beta polypeptide (ATP7B) cause Wilson's disease, located on chromosome 13. It has mainly hepatic and neurological presentations. Movement disorders are a characteristic finding in Wilson's ... ...

    Abstract Mutations in the gene coding for ATPase copper transporting beta polypeptide (ATP7B) cause Wilson's disease, located on chromosome 13. It has mainly hepatic and neurological presentations. Movement disorders are a characteristic finding in Wilson's disease, and "wing-beating tremors" are classical characteristics found on physical examination. We came across and managed a case of Wilson's disease with primarily neurological presentation with classical wing-beating tremors and "face of a giant panda" on radiology. As the patient had very typical findings and he also improved with the treatment, it will be beneficial to the clinicians in their daily practice to identify the disease seeing these clinical findings.
    Language English
    Publishing date 2022-02-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.22429
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Comparison of Obstetric Outcomes Between IVF cycles with Donor Oocyte and Spontaneous Conception Pregnancies: A Retrospective Cohort study.

    Vikas, Yadav / Neena, Malhotra / Reeta, Mahey / Neeta, Singh / Alka, Kriplani

    Journal of reproduction & infertility

    2022  Volume 23, Issue 2, Page(s) 100–106

    Abstract: Background: Oocyte donation has facilitated couples to achieve pregnancy in conditions like diminished ovarian reserve, premature ovarian failure, and inheritable disorders. However, it is unclear whether pregnancy complications are due to oocyte ... ...

    Abstract Background: Oocyte donation has facilitated couples to achieve pregnancy in conditions like diminished ovarian reserve, premature ovarian failure, and inheritable disorders. However, it is unclear whether pregnancy complications are due to oocyte donation per se or due to confounding factors such as maternal age or the allogenic fetus. In this retrospective comparative cohort, an attempt was made to evaluate and compare multiple obstetric and perinatal outcomes.
    Methods: The present study comprised all women in the age range of 20-45 years who conceived from oocyte donation (n=102) between 1/12/2011 to 30/09/2017. Control group consisted of spontaneous conception cases (n=306) in ratio of 1:3 with no previous medical or surgery comorbidity. Obstetric and perinatal outcomes were compared between two groups.
    Results: Mean maternal age was significantly higher in the donor oocyte IVF group (group 1; 35.13 years) as compared to spontaneous conception group (group 2; 31.75 years). Parity between the two groups was comparable. Pregnancy induced hypertension (PIH) was seen in 33.33% of cases in group 1 as compared to 7.18% in group 2. Moreover, gestational diabetes mellitus was seen in 34.31% of cases in group 1 as compared to 9.47% in group 2 (p=0.001). By the same token, there was significant difference in perinatal outcomes between the two groups.
    Conclusion: Oocyte donation should be treated as an independent risk factor for miscarriage, hypertensive disorder, and gestational diabetes mellitus in pregnancy.
    Language English
    Publishing date 2022-07-26
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2548922-7
    ISSN 2251-676X ; 1735-8507 ; 2228-5482 ; 1726-7536
    ISSN (online) 2251-676X ; 1735-8507
    ISSN 2228-5482 ; 1726-7536
    DOI 10.18502/jri.v23i2.8994
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Comparison of Trans-septal Suturing Technique With Polyvinyl Alcohol Sponge-Based Nasal Packing for Hemostasis in Septoplasty.

    Meena, Rukamani / Sharma, Raman / Malhotra, Vikas / Rathore, Praveen K

    Cureus

    2022  Volume 14, Issue 5, Page(s) e25161

    Abstract: Introduction Despite the theoretical advantages of bleeding control, there is increased morbidity in postoperative pain, sleep disturbance, allergy, toxic shock syndrome, and mucosal injury with the nasal packing in septoplasty procedure for deviated ... ...

    Abstract Introduction Despite the theoretical advantages of bleeding control, there is increased morbidity in postoperative pain, sleep disturbance, allergy, toxic shock syndrome, and mucosal injury with the nasal packing in septoplasty procedure for deviated nasal septum. Trans-septal suturing after septoplasty has been advocated as an effective alternative to conventional nasal packing. The current study aims to compare the frequency of subjective symptoms, such as postoperative nasal pain, nasal bleeding, postnasal drip, sleep disturbance, dysphagia, headache, and epiphora between the trans-septal suturing technique and nasal packing in septoplasty surgery. Methods We prospectively recruited all adult septoplasty patients for a one-year duration. Trans-septal nasal suturing was done for hemostasis after septoplasty in the case group. Anterior nasal packing after septoplasty was performed in the control group. The postoperative subjective symptoms were evaluated, such as postoperative nasal pain, nasal bleeding, postnasal drip, sleep disturbance, dysphagia, headache, and epiphora. Procedure-related complications were compared between the two groups. Results A total of 50 patients were recruited for the study (25 in each group). The postoperative symptoms evaluation suggested that the number of patients with postoperative pain was significantly higher in the control group on both occasions. Besides pain, a significantly higher number of patients in the control group had symptoms of nasal bleeding, postnasal drip, sleep disturbance, dysphagia, headache, and epiphora. Conclusion Trans-septal suture technique is an effective alternative to nasal packing with a low risk of nasal pain, bleeding, postnasal drip, epiphora, headache, dysphagia, and sleep disturbance. In addition, there is a low risk of complications like nasal bleeding, septal hematoma, septal perforation, and synechiae formation. The only disadvantage of trans-septal suturing compared to PVA-coated nasal packing is the increase in the operative time.
    Language English
    Publishing date 2022-05-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.25161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Fine needle aspiration cytology of primary thyroid non-hodgkins lymphoma: Experience from a tertiary care center of North India.

    Singh, Meeta / Nain, Gunjan / Jain, Shyama / Singh, Sarika / Malhotra, Vikas

    Journal of cancer research and therapeutics

    2022  Volume 18, Issue 1, Page(s) 185–189

    Abstract: Presentation: Twelve cases of Primary Thyroid Non-Hodgkin's Lymphoma (PT-NHL) were retrieved from the records suspected or diagnosed as NHL on fine needle aspiration cytology (FNAC) over a period of nine years from 2010-2018. During this period 5236 ... ...

    Abstract Presentation: Twelve cases of Primary Thyroid Non-Hodgkin's Lymphoma (PT-NHL) were retrieved from the records suspected or diagnosed as NHL on fine needle aspiration cytology (FNAC) over a period of nine years from 2010-2018. During this period 5236 patients underwent thyroid FNAC;of these 685 cases were diagnosed under Bethesda Caregory V and VI. Thyroid NHL constituted 0.23 % of all thyroid FNA (12/5236 cases)and 1.7% (12/685) of all thyroid malignancies. Patients ranged in age from 40-61 years with Female:Male 7:5. All patients presented with thyroid enlargement (5-14 cms), and were of two months to five years duration. Patients had history of tobacco intake (smoking/chewing)in nine cases (75%). Thyroid function tests showed hypothyroidism in four (33%), positive antithyroid antibodies in three (25%) and; two cases(16.7%) were known cases of Hashimotos thyroiditis with follow up.
    Cytological findings: Eight cases (66.7%) had monomorphic large cell morphology,other four had mostly intermediate cell types (33.3%). A panel of immunocyto/ histochemistry (ICC/ IHC) showed CD 19 and CD 20 positivity in all cases;sixof these could be correlated on Flow cytometry (FC) with expression of FMC7, CD20, CD19 with kappa light chain restriction (5) and Lambda (1). FC findings corroborated completely with IHC on biopsy sections. The final diagnosis were Diffuse large B cell Lymphoma (DLBCL,8) and MALT- Lymphoma(4). The follow up was available in DLBCL (4) and MALT- Lymphoma (1). CHOP therapy were given in all patients followed by radiotherapy in DLBCL; one patient of DLBCL died following pulmonary complications, rest are well and alive on follow-up.
    Discussion: PT-NHL is rare in India. DLBCL is the commonest histological type reported. In the present study, tobacco exposure has shown strong association. Combined FNAC-FC provide definitive diagnosis and thus can replace histopathology reducing turn around time.
    Conclusion: FNAC -FC provides a definitive diagnosis and thus can reduce turnaround time.
    MeSH term(s) Adult ; Biopsy, Fine-Needle ; Female ; Humans ; Lymphoma, Non-Hodgkin/diagnosis ; Lymphoma, Non-Hodgkin/pathology ; Male ; Middle Aged ; Tertiary Care Centers ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/pathology
    Language English
    Publishing date 2022-04-05
    Publishing country India
    Document type Journal Article
    ZDB-ID 2187633-2
    ISSN 1998-4138 ; 0973-1482
    ISSN (online) 1998-4138
    ISSN 0973-1482
    DOI 10.4103/jcrt.JCRT_234_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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